Article ; Online: Targeting signaling pathways involved in primordial follicle growth or dormancy: potential application in prevention of follicular loss and infertility.
Expert opinion on biological therapy
2022 Volume 22, Issue 7, Page(s) 871–881
Abstract: Introduction: Premature ovarian failure (POF) is one of the important causes of infertility in females. To date, no efficient preventive pharmacological treatment has been offered to prevent POF. Therefore, it is necessary to focus on strategies that ... ...
| Abstract | Introduction: Premature ovarian failure (POF) is one of the important causes of infertility in females. To date, no efficient preventive pharmacological treatment has been offered to prevent POF. Therefore, it is necessary to focus on strategies that provide a normal reproductive lifespan to females at risk of developing POF. Areas covered: Recently, attention has been drawn to discovering pathways involved in primordial follicle activation, as the inhibition of this process might maintain the stock of primordial follicles and therefore, prevent POF. Expert opinion: Although the findings seem promising, most of the studies were conducted on animals, and the interaction between these factors and the possible outcomes of their administration in the long term are still unknown. Therefore, further investigation is necessary to assess these aspects. |
|||||
|---|---|---|---|---|---|---|
| MeSH term(s) | Animals ; Anti-Mullerian Hormone/metabolism ; Anti-Mullerian Hormone/pharmacology ; Female ; Humans ; Infertility/metabolism ; Ovarian Follicle/metabolism ; Primary Ovarian Insufficiency/metabolism ; Primary Ovarian Insufficiency/prevention & control ; Signal Transduction | |||||
| Chemical Substances | Anti-Mullerian Hormone (80497-65-0) | |||||
| Language | English | |||||
| Publishing date | 2022-06-08 | |||||
| Publishing country | England | |||||
| Document type | Journal Article ; Review | |||||
| ZDB-ID | 2052501-1 | |||||
| ISSN | 1744-7682 ; 1471-2598 | |||||
| ISSN (online) | 1744-7682 | |||||
| ISSN | 1471-2598 | |||||
| DOI | 10.1080/14712598.2022.2086042 | |||||
| Shelf mark |
|
|||||
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
Full text online
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 6094: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.