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  1. Article ; Online: Papillary Thyroid Microcarcinoma: Differences between Lesions in Incidental and Nonincidental Settings-Considerations on These Clinical Entities and Personal Experience.

    Lucandri, Giorgio / Fiori, Giulia / Falbo, Francesco / Pende, Vito / Farina, Massimo / Mazzocchi, Paolo / Santonati, Assunta / Bosco, Daniela / Spada, Antonio / Santoro, Emanuele

    Current oncology (Toronto, Ont.)

    2024  Volume 31, Issue 2, Page(s) 941–951

    Abstract: Papillary thyroid microcarcinoma (PTMC) represents 35-40% of all papillary cancers; it is defined as a nodule ≤ 10 mm at the time of histological diagnosis. The clinical significance of PTMC is still controversial, and it may be discovered in two ... ...

    Abstract Papillary thyroid microcarcinoma (PTMC) represents 35-40% of all papillary cancers; it is defined as a nodule ≤ 10 mm at the time of histological diagnosis. The clinical significance of PTMC is still controversial, and it may be discovered in two settings: incidental PTMC (iPTMC), in which it is identified postoperatively upon histological examination of thyroid specimens following thyroid surgery for benign disease, and nonincidental PTMC (niPTMC), in which it is diagnosed before surgery. While iPTMC appears to be related to mild behavior and favorable clinical outcomes, niPTMC may exhibit markers of aggressiveness. We retrospectively review our experience, selecting 54 PTMCs: 28 classified as niPTMC (52%) and 26 classified as iPTMC (48%). Patients with niPTMC showed significant differences, such as younger age at diagnosis (
    MeSH term(s) Humans ; Male ; Female ; Retrospective Studies ; Neoplasm Recurrence, Local ; Incidental Findings ; Thyroid Neoplasms/diagnosis ; Carcinoma, Papillary
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol31020070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: L’approccio e la gestione per processi in Pneumologia

    Negro, Roberto Walter / Bizzarri, Giancarlo / Farina, Massimo / Guarneri, Cristiano / Tognella, Silvia

    2005  

    Author's details edited by Roberto Walter Negro, Giancarlo Bizzarri, Cristiano Guarneri, Silvia Tognella, Massimo Farina
    Keywords Economics ; Pneumology ; Public health ; Public health laws ; System safety
    Publisher Springer-Verlag Italia, Milano
    Publishing place Milano
    Document type Book ; Online
    HBZ-ID TT050387906
    ISBN 978-88-470-0326-2 ; 978-88-470-0338-5 ; 88-470-0326-1 ; 88-470-0338-5
    DOI 10.1007/b137425
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: Extended surgical resection for nonfunctioning duodenal neuroendocrine tumor.

    Lucandri, Giorgio / Fiori, Giulia / Lucchese, Sara / Pende, Vito / Farina, Massimo / Giordano, Marco / Santoro, Emanuele

    Journal of surgical case reports

    2022  Volume 2022, Issue 9, Page(s) rjac391

    Abstract: Duodenal neuroendocrine tumors (NETs) account for <3% of all gastrointestinal NET. Most lesions are small-sized and are located in the first or second duodenal part. Tumoral grading, evaluated by Ki67 index, strongly influences patient's outcome. ... ...

    Abstract Duodenal neuroendocrine tumors (NETs) account for <3% of all gastrointestinal NET. Most lesions are small-sized and are located in the first or second duodenal part. Tumoral grading, evaluated by Ki67 index, strongly influences patient's outcome. Endoscopic resection is recommended for lesions measuring <2 cm, while pancreaticoduodenectomy should be the treatment of choice for large duodenal NET; Whipple procedure should be preferred in case of duodenal origin and contiguity with gastric antrum. Involvement of surrounding structures, as well as the presence of resectable liver metastases, does not contraindicate surgical resection. Herein we report a case of a 68-year-old male, presenting with an extensive mass of the descending pre-ampullary duodenal part, with involvement of the right colon and the presence of a pericholecystic single liver metastasis. In spite of such advanced disease, surgery on the patient was successful, with an uneventful postoperative outcome.
    Language English
    Publishing date 2022-09-06
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjac391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Management of low colorectal anastomotic leakage using negative pressure therapy with Transanal Minimally Invasive Surgery (TAMIS): description of a case and review of the literature.

    Pende, Vito / Fiori, Giulia / Lucandri, Giorgio / Genualdo, Flaminia / Lucchese, Sara / Falbo, Francesco / Biancucci, Andrea / Mazzocchi, Paolo / Farina, Massimo / Santoro, Emanuele

    Journal of surgical case reports

    2023  Volume 2023, Issue 3, Page(s) rjad124

    Abstract: Anastomotic leakage (AL) represents a major post-operative complication after low anterior resection (LAR) for rectal cancer. It is associated with increased morbidity, mortality, length of hospital stay and risk of permanent stoma. Herein we report the ... ...

    Abstract Anastomotic leakage (AL) represents a major post-operative complication after low anterior resection (LAR) for rectal cancer. It is associated with increased morbidity, mortality, length of hospital stay and risk of permanent stoma. Herein we report the case of a 75-year-old male patient submitted to a minimally invasive LAR who developed an AL on the fifth post-operative day. This complication has been successfully managed by placing a Vacuum-Assisted Therapy device (Endo-SPONGE®) with an unusual Transanal Minimally Invasive Surgery (TAMIS) approach; the size of the abscess cavity was measured and the Endo-SPONGE® was cut according to the size of the fistulous defect. This procedure has been performed at regular intervals, achieving quick reduction of anastomotic defect. After the discharge from our department, the patient was addressed to adjuvant treatment. TAMIS may represent an alternative to the endoscopic approach to position an Endo-SPONGE® whenever a conservative management of an AL is required.
    Language English
    Publishing date 2023-03-31
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjad124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Hybrid sequential treatment of a giant serous mesenteric cyst: description of a case and review of the literature.

    Lucandri, Giorgio / Fiori, Giulia / Lucchese, Sara / Genualdo, Flaminia / Pende, Vito / Farina, Massimo / Mazzocchi, Paolo / Santoro, Emanuele

    Journal of surgical case reports

    2022  Volume 2022, Issue 9, Page(s) rjac397

    Abstract: Mesenteric cysts are uncommon benign abdominal tumors that may extend from the root of the mesenteric layers of the gastrointestinal tract into the retroperitoneum or the peritoneal cavity; they are usually asymptomatic and often represent an occasional ... ...

    Abstract Mesenteric cysts are uncommon benign abdominal tumors that may extend from the root of the mesenteric layers of the gastrointestinal tract into the retroperitoneum or the peritoneal cavity; they are usually asymptomatic and often represent an occasional finding. Definitive diagnosis is confirmed by the surgical intraoperative view and by histopathological examination. Surgical excision of the cyst is the treatment of choice. We present a case of a female patient who presented with back pain and a palpable abdominal mass. Due to large size of the mass and its contiguity with midline, patient underwent an hybrid combined surgical technique, with a first open phase followed by a laparoscopic excision. Complete surgical removal of the cyst was successfully performed without bowel resection, intraoperative spillage of cystic content and without morbidity. Histopathology confirmed diagnosis of simple mesenteric cyst. We strongly recommend a combined approach whenever a large intraperitoneal benign cystic lesion has been diagnosed.
    Language English
    Publishing date 2022-09-09
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjac397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Small bowel adenocarcinoma: natural history of recurrence after surgical resection.

    Farina, Massimo / Falbo, Francesco / Biancucci, Andrea / Lucandri, Giorgio / Pende, Vito / Mazzocchi, Paolo / Cascini, Francescopaolo / Lembo, Alessandro / Santoro, Emanuele

    Journal of surgical case reports

    2022  Volume 2022, Issue 10, Page(s) rjac451

    Abstract: Small bowel adenocarcinomas (SBA) are a rare entity associated with a poor prognosis and an advanced stage of disease at diagnosis. Surgical resection is considered the gold standard of treatment for stage I-III, while stage IV disease approach is still ... ...

    Abstract Small bowel adenocarcinomas (SBA) are a rare entity associated with a poor prognosis and an advanced stage of disease at diagnosis. Surgical resection is considered the gold standard of treatment for stage I-III, while stage IV disease approach is still debated. We present a case of a young woman affected by a duodenojejunal junction SBA treated with surgical resection and FOLFOX adjuvant chemotherapy. The patient later underwent a palliative duodenojejunal bypass for peritoneal carcinomatosis.
    Language English
    Publishing date 2022-10-27
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjac451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Virtual User in the IoT: Definition, Technologies and Experiments.

    Girau, Roberto / Cossu, Raimondo / Farina, Massimo / Pilloni, Virginia / Atzori, Luigi

    Sensors (Basel, Switzerland)

    2019  Volume 19, Issue 20

    Abstract: Virtualization technologies are characterizing major advancements in the Internet of Things (IoT) arena, as they allow for achieving a cyber-physical world where everything can be found, activated, probed, interconnected, and updated at both the virtual ... ...

    Abstract Virtualization technologies are characterizing major advancements in the Internet of Things (IoT) arena, as they allow for achieving a cyber-physical world where everything can be found, activated, probed, interconnected, and updated at both the virtual and the physical levels. We believe these technologies should apply to human users other than things, bringing us the concept of the Virtual User (VU). This should represent the virtual counterpart of the IoT users with the ultimate goal of: (i) avoiding the user from having the burden of following the tedious processes of setting, configuring and updating IoT services the user is involved in; (ii) acting on behalf of the user when basic operations are required; (iii) exploiting to the best of its ability the IoT potentialities, always taking always account the user profile and interests. Accordingly, the VU is a complex representation of the user and acts as a proxy in between the virtual objects and IoT services and application; to this, it includes the following major functionalities: user profiling, authorization management, quality of experience modeling and management, social networking and context management. In this respect, the major contributions of this paper are to: provide the definition of VU, present the major functionalities, discuss the legal issues related to its introduction, provide some implementation details, and analyze key performance aspects in terms of the capability of the VU to correctly identify the user profile and context.
    Language English
    Publishing date 2019-10-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s19204489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Application of failure mode and effect analysis in total laparoscopic hysterectomy in benign conditions.

    Lijoi, Davide / Farina, Massimo / Puppo, Andrea / Novelli, Antonia / Ferrero, Simone

    Minerva ginecologica

    2019  Volume 71, Issue 4, Page(s) 272–280

    Abstract: Background: Hysterectomy is the most common major gynecological operation in developed countries. The rate of intraoperative complications related to the laparoscopic approach during hysterectomy is a relevant issue. The failure mode and effect analysis ...

    Abstract Background: Hysterectomy is the most common major gynecological operation in developed countries. The rate of intraoperative complications related to the laparoscopic approach during hysterectomy is a relevant issue. The failure mode and effect analysis (FMEA) method is a prospective approach, which tries to identify possible errors before they occur.
    Methods: In this study we applied the FMEA method to laparoscopic approach to hysterectomy in order to reduce the theorized risk of intraoperative complications. We selected a team who analyzed and deconstructed the total laparoscopic hysterectomy (TLH) process recording on the FMEA worksheet phases and activities of the entire procedure. Each activity-related failure mode and their potential effects were developed. The team also described actions to eliminate or decrease the likelihood of mistakes.
    Results: A numerical value reflecting the risk was assigned to each activity. Five activities were identified as high priority risk, and for each activity actions were then taken to mitigate the identified risk. After introduction of these actions, the risk scores for each activity were recalculated, and we obtained a total risk reduction of 55%.
    Conclusions: It is our opinion that the systematic implementation of the FMEA model can reduce the risk of human error during laparoscopic surgery, improving patient safety.
    MeSH term(s) Female ; Genital Diseases, Female/surgery ; Healthcare Failure Mode and Effect Analysis ; Humans ; Hysterectomy/methods ; Intraoperative Complications/epidemiology ; Laparoscopy/methods ; Medical Errors/prevention & control ; Patient Safety ; Risk Assessment/methods ; Risk Management/methods
    Language English
    Publishing date 2019-03-29
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 80159-8
    ISSN 1827-1650 ; 0026-4784 ; 0325-8793
    ISSN (online) 1827-1650
    ISSN 0026-4784 ; 0325-8793
    DOI 10.23736/S0026-4784.19.04227-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Analysis of the approach to risk management in onco-hematology centers: results of a survey in Italy.

    Farina, Massimo / De Paoli, Gianni / Canciani, Monica

    Tumori

    2016  Volume 102, Issue Suppl 1, Page(s) 7–14

    Abstract: Purpose: Raccomandazione 14 (Recommendation 14), issued by the Italian Ministry of Health, is aimed at providing requirements for preventing medication errors with antineoplastic drugs. Raccomandazione 14 covers all steps of the process, from supply to ... ...

    Abstract Purpose: Raccomandazione 14 (Recommendation 14), issued by the Italian Ministry of Health, is aimed at providing requirements for preventing medication errors with antineoplastic drugs. Raccomandazione 14 covers all steps of the process, from supply to administration of therapies with specific conclusive guidance on tools and methods to be adopted for the assessment and management of clinical risk.
    Methods: A form and a score system were designed and provided to healthcare professionals for self-assessment of adherence to Raccomandazione 14. Data were collected during 2014-2015 and a score was given to each item. Specific gaps were listed for each center.
    Results: A total of 27 healthcare institutions participated in the project, with 447 healthcare personnel (physician, nurses, and pharmacists) involved. The mean overall adherence score for all items covered by Raccomandazione 14 was 2.8 (out of 4). Items with scores <2.8 were considered priority targets for intervention for risk mitigation (general requirements, supply, oral administration, therapy management for injected antineoplastic drugs in home care setting administration, and involvement of patients in care process). The other items of Raccomandazione 14 defined as core processes in the management of anticancer therapies achieved an overall mean score of 3.1 (storage/inventory management, prescription, preparation, distribution, and administration). Following the analysis of the results, the 27 participating institutions activated a range of 3-29 actions/institution for improving adherence to best practice requirements.
    Conclusions: The survey was able to identify specific gaps with Raccomandazione 14 at different institutions throughout Italy so that the healthcare professionals involved were able to prioritize improvement actions that should be able to minimize risk in the management of oncologic drugs in the in-hospital setting.
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280962-x
    ISSN 2038-2529 ; 0300-8916
    ISSN (online) 2038-2529
    ISSN 0300-8916
    DOI 10.5301/tj.5000541
    Database MEDical Literature Analysis and Retrieval System OnLINE

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