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  1. Article: Letter to the Editor in response to the article: Warshawski, T. and Warf, C. It is time for an ethical, evidence-based approach to youth presenting to the ED with an opioid overdose. Paediatr Child Health 2019;1-3. doi:10.1093/pch/pxz011.

    Farrell, Catherine

    Paediatrics & child health

    2019  Volume 24, Issue 6, Page(s) 418

    Language English
    Publishing date 2019-07-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2106767-3
    ISSN 1918-1485 ; 1205-7088
    ISSN (online) 1918-1485
    ISSN 1205-7088
    DOI 10.1093/pch/pxz065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5774: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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  2. Article: A systematic review of resprouting in woody plants and potential implications for the management of urban plantings.

    Kenefick, Claire / Livesley, Stephen / Farrell, Claire

    Ecology and evolution

    2024  Volume 14, Issue 1, Page(s) e10839

    Abstract: Naturalistic plantings, such as meadow-style plantings, can improve the quality of urban green spaces through aesthetic, biodiversity and low maintenance features. Species selection for, and maintenance of naturalistic plantings are key to their success. ...

    Abstract Naturalistic plantings, such as meadow-style plantings, can improve the quality of urban green spaces through aesthetic, biodiversity and low maintenance features. Species selection for, and maintenance of naturalistic plantings are key to their success. While herbaceous and grassy meadows can be mowed, naturalistic plantings with woody plants require more intense maintenance to remove biomass and promote resprouting. We aim to understand woody plant responses to diverse disturbance regimes to potentially inform the selection and management of woody species in urban plantings. We conducted a quantitative systematic literature review of 72 papers and investigated what main external (climate, disturbance regime) and internal (buds, life stage, storage reserves) factors influence the resprouting response of woody plants. We found resprouting literature is geographically widespread for woody plants, but studies are skewed towards Temperate climates in USA and Australia, with a focus on high severity and high frequency fire disturbance. Resprouting response was mostly defined as a continuous response to disturbance dependent on disturbance regime, climate and plant traits. Maintenance and management of naturalistic woody plantings, through hard pruning techniques such as coppicing, may be informed by analogous high severity and high frequency disturbance studies. However, the literature on woody plant resprouting has several knowledge gaps for lower severity and lower frequency disturbance regimes and in more arid climates. Future research should evaluate the response of naturalistic woody plantings to disturbance in specific urban contexts.
    Language English
    Publishing date 2024-01-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.10839
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  3. Article: Staff supported community outings among forensic mental health patients: patient characteristics, rehabilitative goals, and (the absence of) adverse outcomes.

    Farrell, Christian / Petersen, Karen L / Hanzouli, Peri / Nicholls, Tonia L

    Frontiers in psychiatry

    2024  Volume 15, Page(s) 1382676

    Abstract: Mental health professionals are tasked with making difficult clinical decisions in treatment settings. In the forensic system, decision making regarding staff supervised community outings (SSCOs) provides a significant challenge due to the need to ... ...

    Abstract Mental health professionals are tasked with making difficult clinical decisions in treatment settings. In the forensic system, decision making regarding staff supervised community outings (SSCOs) provides a significant challenge due to the need to balance patient liberties, mental health recovery, and public safety. This study explored the characteristics and rehabilitative nature of SSCOs, characteristics of patients attending SSCOs, and any adverse events that occurred during the outings. Employing a cross-sectional design, 110 patients who participated in SSCOs over a one-year period from a Canadian Forensic Psychiatric Hospital were included. Clinical records were reviewed to capture patient and SSCO variables. Descriptive analyses were used to calculate participant, risk, SSCO, and adverse event characteristics. Qualitative analysis was used to explore the purpose of SSCOs and rehabilitative progress that occurred during the outings. Patients attending SSCOs were comprised of long-stay patients with over half having committed a violent index offence. Almost 75% of patients had a moderate/high risk for violence and 50% of the patients had a moderate/high risk of absconding. During the study period, 463 SSCOs were completed. Most outings focused on developing skills for daily living and staff comments suggested many patients developed skills in these areas. Despite considerable risk profiles and public concern regarding forensic patients having community access, there was a single occurrence of unauthorized leave and no instances of violence or substance use. This research can disrupt stigma, demonstrating that SSCOs support a specific rehabilitative intent, promote community reintegration, and maintain public safety.
    Language English
    Publishing date 2024-04-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2024.1382676
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  4. Article ; Online: Improving Access to Oral Health Care: Integrating dental hygienists into federally qualified health center obstetrics and gynecology clinics in Michigan.

    Battani, Katy / Norrix, Emily / Sailor, Lindsay / Farrell, Christine

    Journal of dental hygiene : JDH

    2023  Volume 97, Issue 3, Page(s) 7–12

    Abstract: Dental hygienists (DHs) are well positioned to be part of primary care teams to increase access to oral health care, particularly for those who encounter barriers to oral care, such as pregnant people. The Michigan Initiative for Maternal and Infant Oral ...

    Abstract Dental hygienists (DHs) are well positioned to be part of primary care teams to increase access to oral health care, particularly for those who encounter barriers to oral care, such as pregnant people. The Michigan Initiative for Maternal and Infant Oral Health (MIMIOH) integrates DHs into obstetrics and gynecology (OB/GYN) clinics in federally qualified health centers (FQHCs) to improve pregnant people's oral health. Evaluation of the MIMIOH program revealed that selecting DHs with personal characteristics desirable for integrated-care delivery was a major factor for successfully integrating DHs into OB/GYN clinics. Additionally, designing appropriate clinical workflows, gaining buy-in from prenatal health care professionals, presenting oral health care as part of prenatal care, having co-located OB/GYN and dental clinics, and maintaining adequate funding were all critical to program success. Analysis of Medicaid data showed that the MIMIOH model increased the percentage of pregnant people receiving oral health care at FQHC dental clinics. Innovative programs like MIMIOH add to the evidence that integrating DHs into primary care settings can increase access to oral health care, especially for those who face difficulties accessing the traditional oral health care system. There is great potential for DHs to leverage collaborative practice agreements and remote supervision to increase access to oral health care for the public. Providing DHs with autonomy to practice to the highest level of their scope of practice and permitting direct Medicaid reimbursement for DHs would make oral health care more accessible for underserved populations.
    MeSH term(s) Female ; Pregnancy ; United States ; Humans ; Oral Health ; Obstetrics ; Michigan ; Dental Hygienists ; Delivery of Health Care
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1035719-1
    ISSN 1553-0205 ; 1043-254X
    ISSN (online) 1553-0205
    ISSN 1043-254X
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  5. Article ; Online: Alveolar soft part sarcoma: Prolonged response to immune checkpoint inhibitors.

    Titapiwatanakun, Ruetima / Farrell, Crystal / Fernandez, Karen S

    Pediatric blood & cancer

    2023  , Page(s) e30414

    Language English
    Publishing date 2023-05-12
    Publishing country United States
    Document type Letter
    ZDB-ID 2131448-2
    ISSN 1545-5017 ; 1545-5009
    ISSN (online) 1545-5017
    ISSN 1545-5009
    DOI 10.1002/pbc.30414
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1131: Show issues Location:
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  6. Article ; Online: Exploring the Overlap Between Sexual Victimization and Offending Among Young Women Across Neighborhoods: Does the Type of Force and Type of Offending Matter?

    Farrell, Chelsea

    Journal of interpersonal violence

    2017  Volume 35, Issue 3-4, Page(s) 571–599

    Abstract: The relationship between victimization and subsequent maladaptive behaviors such as offending is well established. To a lesser degree, a contextual lens has been used to examine how neighborhood characteristics influence the overlap between victimization ...

    Abstract The relationship between victimization and subsequent maladaptive behaviors such as offending is well established. To a lesser degree, a contextual lens has been used to examine how neighborhood characteristics influence the overlap between victimization and offending. The existing literature has yet to explore how the neighborhood context moderates the victim-offender overlap among young women, specifically, or whether the type of force used during sexual victimization or offending matters. This study uses data from The National Longitudinal Study of Adolescent to Adult Health (Add Health) to examine whether concentrated disadvantage moderates the impact of sexual victimization on subsequent offending for women. Results indicate that young women who experience sexual victimization are more likely to engage in general offending regardless of neighborhood type. However, closer examination reveals that, when taking into account the type of force used in sexual victimization (physical or coerced) and the type of offending (violent, property, drug use), the overlap does indeed vary across neighborhoods. Specifically, results indicate that only coerced sexual victimization significantly affects property offending in neighborhoods with high levels of concentrated disadvantage. Related to violent offending, physical sexual victimization has a strong positive impact in less disadvantaged neighborhoods. Finally, coerced sexual victimization is significantly associated with an increased likelihood for drug use, and this relationship is consistent across neighborhoods. The findings suggest that nuances in the nature of victimization and offending need to be taken into account to fully understand the victim-offender overlap across neighborhood context.
    MeSH term(s) Adolescent ; Aggression/psychology ; Bullying/psychology ; Crime Victims/psychology ; Criminals/psychology ; Female ; Humans ; Juvenile Delinquency/psychology ; Longitudinal Studies ; Risk Factors ; Sexual Behavior/psychology ; Young Adult
    Language English
    Publishing date 2017-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2028900-5
    ISSN 1552-6518 ; 0886-2605
    ISSN (online) 1552-6518
    ISSN 0886-2605
    DOI 10.1177/0886260516689778
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  7. Article ; Online: Occluded Portex Epifuse™ epidural connector.

    Farrell, C

    Anaesthesia

    2012  Volume 67, Issue 3, Page(s) 307

    MeSH term(s) Anesthesia, Epidural/instrumentation ; Hospitals, General ; Humans
    Language English
    Publishing date 2012-03
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 80033-8
    ISSN 1365-2044 ; 0003-2409
    ISSN (online) 1365-2044
    ISSN 0003-2409
    DOI 10.1111/j.1365-2044.2012.07079_3.x
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 388: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  8. Article: Fast plants have water-use and drought strategies that balance rainfall retention and drought survival on green roofs.

    Chu, Hsiao-Hsuan / Farrell, Claire

    Ecological applications : a publication of the Ecological Society of America

    2021  Volume 32, Issue 1, Page(s) e02486

    Abstract: Green roofs can improve ecosystem services in cities; however, this depends on appropriate plant selection. For stormwater management, plants should have high water use to maximize retention and also survive dry periods. Plants adapted to wetter habitats ...

    Abstract Green roofs can improve ecosystem services in cities; however, this depends on appropriate plant selection. For stormwater management, plants should have high water use to maximize retention and also survive dry periods. Plants adapted to wetter habitats develop "fast" traits for growth, whereas plants from drier habitats develop "slow" traits to conserve water use and survive drought. Therefore, we hypothesized that (1) plants with fast traits would have greater water use, (2) plants with slow traits would have greater drought tolerance, (3) fast-slow traits would be consistent across the plant, and (4) fast plants with greater water use could avoid drought stress. We evaluated 14 green roof species in a glasshouse experiment under well-watered (WW) and water-deficit (WD) conditions to determine relationships between fast-slow traits, water use, and drought resistance. Traits measured were shoot dry mass, specific leaf area (SLA), root mass fraction (RMF), and specific root length (SRL). Daily evapotranspiration per shoot dry mass was used to describe water use. Drought resistance was represented by (1) days to stomatal closure; (2) cumulative ET before stomatal closure; and (3) degree of iso-anisohydry (difference between midday leaf water potential (Ψ
    MeSH term(s) Droughts ; Ecosystem ; Plant Leaves ; Plants ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2021-12-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1074505-1
    ISSN 1939-5582 ; 1051-0761
    ISSN (online) 1939-5582
    ISSN 1051-0761
    DOI 10.1002/eap.2486
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    Z 5240: Show issues

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  9. Article ; Online: Bioindicators of severe ocean acidification are absent from the end-Permian mass extinction.

    Foster, William J / Hirtz, J A / Farrell, C / Reistroffer, M / Twitchett, R J / Martindale, R C

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 1202

    Abstract: The role of ocean acidification in the end-Permian mass extinction is highly controversial with conflicting hypotheses relating to its timing and extent. Observations and experiments on living molluscs demonstrate that those inhabiting acidic settings ... ...

    Abstract The role of ocean acidification in the end-Permian mass extinction is highly controversial with conflicting hypotheses relating to its timing and extent. Observations and experiments on living molluscs demonstrate that those inhabiting acidic settings exhibit characteristic morphological deformities and disordered shell ultrastructures. These deformities should be recognisable in the fossil record, and provide a robust palaeo-proxy for severe ocean acidification. Here, we use fossils of originally aragonitic invertebrates to test whether ocean acidification occurred during the Permian-Triassic transition. Our results show that we can reject a hypothesised worldwide basal Triassic ocean acidification event owing to the absence of deformities and repair marks on bivalves and gastropods from the Triassic Hindeodus parvus Conodont Zone. We could not, however, utilise this proxy to test the role of a hypothesised acidification event just prior to and/or during the mass extinction event. If ocean acidification did develop during the mass extinction event, then it most likely only occurred in the latest Permian, and was not severe enough to impact calcification.
    Language English
    Publishing date 2022-01-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-04991-9
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  10. Article ; Online: Identifying epigenetic aging moderators using the epigenetic pacemaker.

    Farrell, Colin / Hu, Chanyue / Lapborisuth, Kalsuda / Pu, Kyle / Snir, Sagi / Pellegrini, Matteo

    Frontiers in bioinformatics

    2024  Volume 3, Page(s) 1308680

    Abstract: Epigenetic clocks are DNA methylation-based chronological age prediction models that are commonly employed to study age-related biology. The difference between the predicted and observed age is often interpreted as a form of biological age acceleration, ... ...

    Abstract Epigenetic clocks are DNA methylation-based chronological age prediction models that are commonly employed to study age-related biology. The difference between the predicted and observed age is often interpreted as a form of biological age acceleration, and many studies have measured the impact of environmental and disease-associated factors on epigenetic age. Most epigenetic clocks are fit using approaches that minimize the error between the predicted and observed chronological age, and as a result, they may not accurately model the impact of factors that moderate the relationship between the actual and epigenetic age. Here, we compare epigenetic clocks that are constructed using penalized regression methods to an evolutionary framework of epigenetic aging with the epigenetic pacemaker (EPM), which directly models DNA methylation as a function of a time-dependent epigenetic state. In simulations, we show that the value of the epigenetic state is impacted by factors such as age, sex, and cell-type composition. Next, in a dataset aggregated from previous studies, we show that the epigenetic state is also moderated by sex and the cell type. Finally, we demonstrate that the epigenetic state is also moderated by toxins in a study on polybrominated biphenyl exposure. Thus, we find that the pacemaker provides a robust framework for the study of factors that impact epigenetic age acceleration and that the effect of these factors may be obscured in traditional clocks based on linear regression models.
    Language English
    Publishing date 2024-01-03
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-7647
    ISSN (online) 2673-7647
    DOI 10.3389/fbinf.2023.1308680
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