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  1. Article: Functional profiling of the

    Giuliano, Christopher J / Wei, Kenneth J / Harling, Faye M / Waldman, Benjamin S / Farringer, Madeline A / Boydston, Elizabeth A / Lan, Tammy C T / Thomas, Raina W / Herneisen, Alice L / Sanderlin, Allen G / Coppens, Isabelle / Dvorin, Jeffrey D / Lourido, Sebastian

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Within a host, pathogens encounter a diverse and changing landscape of cell types, nutrients, and immune responses. Examining host-pathogen interactions in animal models can therefore reveal aspects of infection absent from cell culture. We use CRISPR- ... ...

    Abstract Within a host, pathogens encounter a diverse and changing landscape of cell types, nutrients, and immune responses. Examining host-pathogen interactions in animal models can therefore reveal aspects of infection absent from cell culture. We use CRISPR-based screens to functionally profile the entire genome of the model apicomplexan parasite
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.03.05.531216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Artemisinin resistance mutations in

    Ullah, Imran / Farringer, Madeline A / Burkhard, Anna Y / Hathaway, Erica / Willett, Bailey C / Khushu, Malhar / Shin, Sara H / Sharma, Aabha I / Shao, Kairon L / Martin, Morgan C / Dvorin, Jeffrey D / Hartl, Daniel L / Volkman, Sarah K / Bopp, Selina / Absalon, Sabrina / Wirth, Dyann F

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Artemisinin (ART) combination therapies have been critical in reducing malaria morbidity and mortality, but these important drugs are threatened by growing resistance associated with mutations ... ...

    Abstract Artemisinin (ART) combination therapies have been critical in reducing malaria morbidity and mortality, but these important drugs are threatened by growing resistance associated with mutations in
    Language English
    Publishing date 2023-12-22
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.12.22.572193
    Database MEDical Literature Analysis and Retrieval System OnLINE

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