Article: [Disorders in lipid composition and properties of plasma membrane in epithelial cells of the placental villous chorion in chlamydial infection].
Ukrains'kyi biokhimichnyi zhurnal (1999 )
2008 Volume 80, Issue 2, Page(s) 135–140
Abstract: Lipid composition of plasma membranes of placental epithelial cells of villous chorion of healthy women and those with chlamydiosis has been studied. Lipid composition of plasma membranes of ill women differs from that of healthy women by reduction of ... ...
| Abstract | Lipid composition of plasma membranes of placental epithelial cells of villous chorion of healthy women and those with chlamydiosis has been studied. Lipid composition of plasma membranes of ill women differs from that of healthy women by reduction of total phospholipids quantity, by the increase of the level of free cholesterol and free fatty acids. A disturbance in the ratio between certain lipid fractions and increasing quantity of lysophospholipids is observed. Two-fold oppression of plasma membranes Na+, K+ -ATPase activity of placental epithelial cells of villous chorion in ill women has been detected but Mg2+, Ca2+ -ATPase activity has not changed. Thus chlamydial infection causes significant disorders in lipid composition and functioning of epithelial cells membranes of chorion. |
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| MeSH term(s) | Ca(2+) Mg(2+)-ATPase/metabolism ; Cell Membrane/enzymology ; Cell Membrane/metabolism ; Chlamydia Infections/metabolism ; Chorionic Villi/metabolism ; Epithelial Cells/enzymology ; Epithelial Cells/metabolism ; Female ; Humans ; Membrane Lipids/metabolism ; Phospholipids/metabolism ; Pregnancy ; Pregnancy Complications, Infectious/metabolism ; Sodium-Potassium-Exchanging ATPase/metabolism |
| Chemical Substances | Membrane Lipids ; Phospholipids ; Ca(2+) Mg(2+)-ATPase (EC 3.6.1.-) ; Sodium-Potassium-Exchanging ATPase (EC 3.6.3.9) |
| Language | Ukrainian |
| Publishing date | 2008-03 |
| Publishing country | Ukraine |
| Document type | English Abstract ; Journal Article |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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