LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Zurück zur letzten Suche Suchhistorie
Erweiterte Suche

Ihre letzten Suchen

  1. AU="Fathimathu, Zuhara"
  2. AU="Barbara I Kazmierczak"
  3. AU=Gendron Joshua M
  4. AU="Klaaßen-Mielke, Renate"
  5. AU=Rao Saieesh A AU=Rao Saieesh A
  6. AU="Md. Arifur Rahman Munshi"
  7. AU=Gorbunova Vera
  8. AU="Mathias Uhlen"
  9. AU="Torrens, Alexa"
  10. AU="Moloney, E"
  11. AU="Pulawski, S."
  12. AU="Ustuner, Mehmet Cengiz"
  13. AU="Solozhentseva, Kristina"
  14. AU="Sitar, Cristian"
  15. AU="Ahmed, Md Firoz"
  16. AU=Goldberg Elad
  17. AU="Moskowitz, Jeremy D"
  18. AU="Mugunthan, Susithra Priyadarshni"
  19. AU="Matini, Lawrence"
  20. AU="Pourova, Radka"
  21. AU="Saxena, Shweta"
  22. AU="McGovern, Sophie"
  23. AU="Shuai An"
  24. AU="Kirill S. Golokhvast"
  25. AU="Cho, Kwang-Hwi"
  26. AU="Davitoiu, Dragos"
  27. AU=Templeman Charles
  28. AU="Attaluri, Anilchandra"
  29. AU="Cox, Ryan M"
  30. AU="Barua, Melissa"
  31. AU=Wong Ngai-Sze
  32. AU="Salgotra, Romesh Kumar"
  33. AU="Rossano, Adam J"
  34. AU="Pfeiffer, Christian"
  35. AU="Klostermann, Cynthia E."
  36. AU="Ivory, Joannie M"
  37. AU="Sooltangos, Aisha"
  38. AU="Marcia Adriana Poll"
  39. AU="Wenzel, Ross"
  40. AU="Wang, Ruihan"
  41. AU=Qing Enya AU=Qing Enya
  42. AU=Xu Jian AU=Xu Jian

Suchergebnis

Treffer 1 - 3 von insgesamt 3

Suchoptionen

  1. Artikel ; Online: Response surface methodological optimization of L-asparaginase production from the medicinal plant endophyte Acinetobacter baumannii ZAS1.

    Abhini, K N / Rajan, Akhila B / Fathimathu Zuhara, K / Sebastian, Denoj

    Journal, genetic engineering & biotechnology

    2022  Band 20, Heft 1, Seite(n) 22

    Abstract: Background: This study targets the enhanced production of L-asparaginase, an antitumor enzyme by Acinetobacter baumannii ZAS1. This organism is an endophyte isolated from the medicinal plant Annona muricata. Plackett-Burman design (PBD) and central ... ...

    Abstract Background: This study targets the enhanced production of L-asparaginase, an antitumor enzyme by Acinetobacter baumannii ZAS1. This organism is an endophyte isolated from the medicinal plant Annona muricata. Plackett-Burman design (PBD) and central composite design (CCD) were used for statistical optimization of media components.
    Results: The organism exhibited 18.85 ± 0.2 U/mL enzyme activities in unoptimized media. Eight variables: L-asparagine, peptone, glucose, lactose, yeast extract, NaCl, MgSO
    Conclusion: The findings of this study indicated that an endophyte, Acinetobacter baumannii ZAS1 that produces L-asparaginase could be used to increase enzyme output. However, using the statistical methods Plackett-Burman design and central composite design of response surface methodology is a handy tool for optimizing media components for increased L-asparaginase synthesis.
    Sprache Englisch
    Erscheinungsdatum 2022-02-09
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2637420-1
    ISSN 2090-5920 ; 1687-157X ; 2090-5920
    ISSN (online) 2090-5920
    ISSN 1687-157X ; 2090-5920
    DOI 10.1186/s43141-022-00309-4
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  2. Artikel ; Online: Anticancer Activity of the Bioactive Extract of the Morel Mushroom (Morchella elata, Ascomycetes) from Kashmir Himalaya (India) and Identification of Major Bioactive Compounds.

    Ramya, Haridas / Ravikumar, Korattuvalappil S / Ajith, Thekkuttparambil A / Fathimathu, Zuhara / Janardhanan, Kainoor Krishnankutty

    International journal of medicinal mushrooms

    2023  Band 25, Heft 11, Seite(n) 41–52

    Abstract: Morel mushrooms, Morchella species are highly nutritional, excellently edible and medicinal. Anticancer activity of M. elata, growing in forests of Kashmir Himalaya was studied. Ethyl acetate extract of fruiting bodies of M. elata (MEAE) was evaluated ... ...

    Abstract Morel mushrooms, Morchella species are highly nutritional, excellently edible and medicinal. Anticancer activity of M. elata, growing in forests of Kashmir Himalaya was studied. Ethyl acetate extract of fruiting bodies of M. elata (MEAE) was evaluated for cytotoxicity by MTT assay using Daltons lymphoma ascites (DLA), human colon cancer (HCT-116) and normal cell lines. Anti-carcinogenic and antiangiogenic activities of MEAE were tested using mouse models. Proapoptotic activity was detected by double staining of acridine orange-ethidium bromide assay. MEAE was partially purified by column chromatography and the bioactive compounds were identified by LC-MS analysis. The bioactive extract of M. elata showed significant cytotoxicic activity against DLA (P < 0.05), HCT-116 cell lines (P < 0.05) and did not possess appreciable adverse effect on the viability of normal cells. At a concentration of 100 µg/mL, 60% cell death was observed in HCT-116 cell line while 80% cell death was found in DLA cell line. The extract also possessed profound anticarcinogenic, antiangiogenic and proapoptotic activities. LC-MS analysis showed celastrol (RT 9.504, C29H38O4, MW 450.27), convallatoxin (RT 9.60, C29H42O10, MW 550.27), cucurbitacin A (RT 11.97, C32H46O9, MW 574.71) and madecassic acid (RT 14.35, C30H48O6, MW 504.70) as the major bioactive components. Current experimental studies indicated that bioactive extract of M. elata possessed significant anticancer activity. Being an excellently edible mushroom, the potential therapeutic use of M. elata and its bioactive extract in complementary therapy of cancer is envisaged.
    Mesh-Begriff(e) Animals ; Mice ; Humans ; Agaricales ; Ascomycota/chemistry ; HCT116 Cells ; India
    Sprache Englisch
    Erscheinungsdatum 2023-10-13
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2108803-2
    ISSN 1940-4344 ; 1521-9437
    ISSN (online) 1940-4344
    ISSN 1521-9437
    DOI 10.1615/IntJMedMushrooms.2023050169
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Bonn

    Z 7482: Hefte anzeigen

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  3. Artikel ; Online: Morel mushroom,

    Ramya, Haridas / Ravikumar, Korattuvalappil S / Fathimathu, Zuhara / Janardhanan, Kainoor K / Ajith, Thekkuttuparambil A / Shah, Manzoor Ahmad / Farooq, Ramona / Reshi, Zafar A

    Drug and chemical toxicology

    2021  Band 45, Heft 5, Seite(n) 2014–2023

    Abstract: Morel mushrooms, ...

    Abstract Morel mushrooms,
    Mesh-Begriff(e) Agaricales ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Arthritis/chemically induced ; Arthritis/drug therapy ; Edema/chemically induced ; Edema/drug therapy ; Free Radicals/therapeutic use ; NF-kappa B ; Plant Extracts/chemistry
    Chemische Substanzen Anti-Inflammatory Agents ; Free Radicals ; NF-kappa B ; Plant Extracts
    Sprache Englisch
    Erscheinungsdatum 2021-03-07
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 548368-2
    ISSN 1525-6014 ; 0148-0545
    ISSN (online) 1525-6014
    ISSN 0148-0545
    DOI 10.1080/01480545.2021.1894750
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 1380: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

Zum Seitenanfang