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  1. Article ; Online: Changes in spinal motor behaviour are associated with reduction in disability in chronic low back pain: A longitudinal cohort study with 1-year follow-up.

    Christe, Guillaume / Benaim, Charles / Jolles, Brigitte M / Favre, Julien

    European journal of pain (London, England)

    2024  

    Abstract: Background: The need to improve spinal motor behaviour in chronic low back pain (CLBP) rehabilitation remains unclear. The objective of this study was to test if changes in spinal motor behaviour were associated with changes in disability after an ... ...

    Abstract Background: The need to improve spinal motor behaviour in chronic low back pain (CLBP) rehabilitation remains unclear. The objective of this study was to test if changes in spinal motor behaviour were associated with changes in disability after an interdisciplinary rehabilitation program (IRP) in patients with CLBP.
    Methods: Seventy-one patients with CLBP participating in an IRP were included. Spinal motor behaviour was assessed with biomechanical (lumbar angular amplitude and velocity, erector spinae muscle activity and duration of the task), cognitive-emotional (task-specific fear [PRF]) and pain-related (movement-evoked pain [MEP]) measures during a lifting task before and after the IRP. Disability was measured before and after the IRP, and at 3-month and 1-year follow-ups.
    Results: After adjusting for confounders, changes in disability were significantly associated with MEP changes (β adj. = 0.49, p < 0.001) and PRF changes (β adj. = 0.36, p = 0.008), but not with changes in any of the biomechanical measures. MEP at the end of IRP was also associated with disability at 3 months (β adj. = 0.37, p = 0.001) and 1 year (β adj. = 0.42, p = 0.01). Biomechanical measures at the end of the IRP were not associated with disability, except for the duration of the task that was significantly associated with reduction of disability at 3 months (β non-adj = 0.5, p < 0.001).
    Conclusions: Pain-related and cognitive-emotional measures of spinal motor behaviour were associated with reduction in disability following an IRP. Future research is needed to further investigate causal relationships between spinal motor behaviour and disability.
    Significance statement: This study supports a multidimensional understanding and analysis of spinal motor behaviour, integrating the cognitive-emotional, pain-related and biomechanical domains. It also supports the consideration of spinal motor behaviour as a potentially important treatment target in chronic low back pain management. Moreover, it suggests that reducing movement-evoked pain and task-specific fear may have more influence on disability than changing lumbar amplitude, lumbar angular velocity or erector muscle activity, which may have important implications for rehabilitation.
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1390424-3
    ISSN 1532-2149 ; 1090-3801
    ISSN (online) 1532-2149
    ISSN 1090-3801
    DOI 10.1002/ejp.2245
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Rehabilitation for Musculoskeletal Disorders: The Emergence of Serious Games and the Promise of Personalized Versions Using Artificial Intelligence.

    Favre, Julien / Cantaloube, Alexis / Jolles, Brigitte M

    Journal of clinical medicine

    2023  Volume 12, Issue 16

    Abstract: According to the World Health Organization (WHO), musculoskeletal conditions are among the most common health problems, affecting approximately 1 [ ... ]. ...

    Abstract According to the World Health Organization (WHO), musculoskeletal conditions are among the most common health problems, affecting approximately 1 [...].
    Language English
    Publishing date 2023-08-15
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12165310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Simultaneous Evaluation of Bone Cut and Implant Placement Accuracy in Robotic-Assisted Total Knee Arthroplasty.

    Cosendey, Killian / Stanovici, Julien / Cadas, Hugues / Omoumi, Patrick / Jolles, Brigitte M / Favre, Julien

    Journal of clinical medicine

    2024  Volume 13, Issue 5

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-02-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13051293
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  4. Article ; Online: Walking with shorter stride length could improve knee kinetics of patients with medial knee osteoarthritis.

    Ulrich, Baptiste / Pereira, Luís C / Jolles, Brigitte M / Favre, Julien

    Journal of biomechanics

    2023  Volume 147, Page(s) 111449

    Abstract: Walking with a shorter stride length (SL) was recently proposed for gait retraining in medial knee osteoarthritis; however it was never assessed in this patient population. This study tested the hypothesis that shortening SL while maintaining walking ... ...

    Abstract Walking with a shorter stride length (SL) was recently proposed for gait retraining in medial knee osteoarthritis; however it was never assessed in this patient population. This study tested the hypothesis that shortening SL while maintaining walking speed reduces knee adduction (KAM) and flexion (KFM) moments in patients with medial knee osteoarthritis. Walking trials with normal SL and SL reduced by 0.10 m and 0.15 m were recorded for 15 patients (10 men, 55.5 ± 8.7 years old, 24.6 ± 3.0 kg/m
    MeSH term(s) Humans ; Male ; Middle Aged ; Analysis of Variance ; Biomechanical Phenomena ; Gait/physiology ; Knee Joint/physiology ; Osteoarthritis, Knee ; Walking/physiology ; Female
    Language English
    Publishing date 2023-01-12
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 218076-5
    ISSN 1873-2380 ; 0021-9290
    ISSN (online) 1873-2380
    ISSN 0021-9290
    DOI 10.1016/j.jbiomech.2023.111449
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Between/within-session reliability of spinal kinematic and lumbar muscle activity measures in patients with chronic low back pain and asymptomatic individuals.

    Christe, Guillaume / Jolles, Brigitte M / Favre, Julien

    Gait & posture

    2022  Volume 95, Page(s) 100–108

    Abstract: Background: Longitudinal research is required to better understand the role of spinal movement alterations in chronic low back pain (CLBP). To this end, it is critical to assess the between-session reliability of spinal movement measures.: Research ... ...

    Abstract Background: Longitudinal research is required to better understand the role of spinal movement alterations in chronic low back pain (CLBP). To this end, it is critical to assess the between-session reliability of spinal movement measures.
    Research question: What is the within/between-session reliability of spinal movement measures in patients with CLBP and asymptomatic controls?
    Methods: Spinal movement was recorded prospectively during two sessions, a week apart, for 20 patients with CLBP (60% male; 40.0 ± 12.3 years old) and 20 asymptomatic individuals (55% male; 38.2 ± 10.9 years old). Sagittal-plane angular amplitude and angular velocity at the lower lumbar, upper lumbar, lower thoracic and upper thoracic joints, as well as maximal erector spinae activity were measured during five daily-activity tasks. In addition, task-independent measures were obtained by averaging the measures across tasks. The Intraclass Correlation Coefficient (ICC 2,1) and the minimal detectable change (MDC) were calculated. Pearson correlation was used to compare task-independent and task-specific measures.
    Results: Between-session ICCs in patients with CLBP were mostly moderate to good for maximal angular amplitude and erector spinae activity measures. Lower ICCs were observed for range of angular motion and angular velocity measures (42% of ICCs < 0.5). Median MDCs were 9.6°, 18.3°/s and 1.0% for angular amplitude, angular velocity and erector spinae activity measures, respectively. The reliability of task-independent and task-specific measures was strongly correlated (r = 0.91, p < 0.001).
    Significance: Sagittal-plane maximal angular amplitude and erector spinae activity measures during various daily-activity tasks demonstrated mostly moderate to good between-session ICCs. However, relatively large MDCs suggested that important changes are needed to be detectable. Task-independent measures reported similarly acceptable ICCs than task-specific measures, supporting their use to describe spinal movement.
    MeSH term(s) Adult ; Biomechanical Phenomena ; Electromyography ; Female ; Humans ; Low Back Pain ; Lumbar Vertebrae/physiology ; Male ; Middle Aged ; Muscle, Skeletal/physiology ; Paraspinal Muscles ; Range of Motion, Articular/physiology ; Reproducibility of Results
    Language English
    Publishing date 2022-04-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1162323-8
    ISSN 1879-2219 ; 0966-6362
    ISSN (online) 1879-2219
    ISSN 0966-6362
    DOI 10.1016/j.gaitpost.2022.04.008
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  6. Article: Machine learning-based model of surface tension of liquid metals: a step in designing multicomponent alloys for additive manufacturing

    Assi, Mariam / Favre, Julien / Fraczkiewicz, Anna / Tancret, Franck

    Journal of materials science. 2022 July, v. 57, no. 28

    2022  

    Abstract: The surface tension (ST) of metallic alloys is a key property in many processing techniques. Notably, the ST value of liquid metals is crucial in additive manufacturing processes as it has a direct effect on the stability of the melt pool. Although ... ...

    Abstract The surface tension (ST) of metallic alloys is a key property in many processing techniques. Notably, the ST value of liquid metals is crucial in additive manufacturing processes as it has a direct effect on the stability of the melt pool. Although several theoretical models have been proposed to describe the ST, mainly in binary systems, both experimental studies and existing theoretical models focus on simple systems. This study presents a machine learning model based on Gaussian process regression to predict the surface tension of multi-component metallic systems. The model is built and tested on available experimental data from the literature. It is shown that the model accurately predicts the ST value of binaries and ternaries with high precision, and that identifying certain trends in the ST values as a function of alloy composition is possible. The ability of the model to extrapolate to higher-order systems, especially novel concentrated alloys (high entropy alloys, HEA), is discussed.
    Keywords alloys ; entropy ; liquids ; normal distribution ; surface tension
    Language English
    Dates of publication 2022-07
    Size p. 13446-13466.
    Publishing place Springer US
    Document type Article
    ZDB-ID 2015305-3
    ISSN 1573-4803 ; 0022-2461
    ISSN (online) 1573-4803
    ISSN 0022-2461
    DOI 10.1007/s10853-022-07441-z
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Accuracy and Reliability of Pelvimetry Measures Obtained by Manual or Automatic Labeling of Three-Dimensional Pelvic Models.

    Hêches, Johann / Marcadent, Sandra / Fernandez, Anna / Adjahou, Stephen / Meuwly, Jean-Yves / Thiran, Jean-Philippe / Desseauve, David / Favre, Julien

    Journal of clinical medicine

    2024  Volume 13, Issue 3

    Abstract: 1) ...

    Abstract (1)
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030689
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  8. Article: Slowing gait during turning: how volition of modifying walking speed affects the gait pattern in healthy adults.

    Madrid, Julian / Benning, Leo / Selig, Mischa / Ulrich, Baptiste / Jolles, Brigitte M / Favre, Julien / Benninger, David H

    Frontiers in human neuroscience

    2024  Volume 18, Page(s) 1269772

    Abstract: Background: Turning during walking and volitionally modulating walking speed introduces complexity to gait and has been minimally explored.: Research question: How do the spatiotemporal parameters vary between young adults walking at a normal speed ... ...

    Abstract Background: Turning during walking and volitionally modulating walking speed introduces complexity to gait and has been minimally explored.
    Research question: How do the spatiotemporal parameters vary between young adults walking at a normal speed and a slower speed while making 90°, 180°, and 360° turns?
    Methods: In a laboratory setting, the spatiotemporal parameters of 10 young adults were documented as they made turns at 90°, 180°, and 360°. A generalized linear model was utilized to determine the effect of both walking speed and turning amplitude.
    Results: Young adults volitionally reducing their walking speed while turning at different turning amplitudes significantly decreased their cadence and spatial parameters while increasing their temporal parameters. In conditions of slower movement, the variability of certain spatial parameters decreased, while the variability of some temporal parameters increased.
    Significance: This research broadens the understanding of turning biomechanics in relation to volitionally reducing walking speed. Cadence might be a pace gait constant synchronizing the rhythmic integration of several inputs to coordinate an ordered gait pattern output. Volition might up-regulate or down-regulate this pace gait constant (i.e., cadence) which creates the feeling of modulating walking speed.
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2425477-0
    ISSN 1662-5161
    ISSN 1662-5161
    DOI 10.3389/fnhum.2024.1269772
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  9. Article: Walking with Different Insoles Changes Lower-Limb Biomechanics Globally in Patients with Medial Knee Osteoarthritis.

    Jaques, Guillaume / Ulrich, Baptiste / Hoffmann, Laurent / Jolles, Brigitte M / Favre, Julien

    Journal of clinical medicine

    2023  Volume 12, Issue 5

    Abstract: Using insoles to modify walking biomechanics is of keen interest for the treatment of medial-compartment knee osteoarthritis. So far, insole interventions have focused on reducing the peak of the knee adduction moment (pKAM) and have led to inconsistent ... ...

    Abstract Using insoles to modify walking biomechanics is of keen interest for the treatment of medial-compartment knee osteoarthritis. So far, insole interventions have focused on reducing the peak of the knee adduction moment (pKAM) and have led to inconsistent clinical outcomes. This study aimed to evaluate the changes in other gait variables related to knee osteoarthritis when patients walk with different insoles to provide insights into the necessity to enlarge the biomechanical analyses to other variables. Walking trials were recorded for 10 patients in four insole conditions. Changes among conditions were computed for six gait variables, including the pKAM. The associations between the changes in pKAM and the changes in the other variables were also assessed individually. Walking with different insoles had noticeable effects on the six gait variables, with high heterogeneity among patients. For all variables, at least 36.67% of the changes were of medium-to-large effect size. The associations with the changes in pKAM varied among variables and patients. In conclusion, this study showed that varying the insole could globally influence ambulatory biomechanics and that limiting measurement to the pKAM could lead to an important loss of information. Beyond the consideration of additional gait variables, this study also encourages personalized interventions to address inter-patient variability.
    Language English
    Publishing date 2023-03-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12052016
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  10. Article: Could Gait Biomechanics Become a Marker of Atypical Neuronal Circuitry in Human Development?-The Example of Autism Spectrum Disorder.

    Jequier Gygax, Marine / Maillard, Anne M / Favre, Julien

    Frontiers in bioengineering and biotechnology

    2021  Volume 9, Page(s) 624522

    Abstract: This perspective paper presents converging recent knowledge in neurosciences (motor neurophysiology, neuroimaging and neuro cognition) and biomechanics to outline the relationships between maturing neuronal network, behavior, and gait in human ... ...

    Abstract This perspective paper presents converging recent knowledge in neurosciences (motor neurophysiology, neuroimaging and neuro cognition) and biomechanics to outline the relationships between maturing neuronal network, behavior, and gait in human development. Autism Spectrum Disorder (ASD) represents a particularly relevant neurodevelopmental disorder (NDD) to study these convergences, as an early life condition presenting with sensorimotor and social behavioral alterations. ASD diagnosis relies solely on behavioral criteria. The absence of biological marker in ASD is a main challenge, and hampers correlations between behavioral development and standardized data such as brain structure alterations, brain connectivity, or genetic profile. Gait, as a way to study motor system development, represents a well-studied, early life ability that can be characterized through standardized biomechanical analysis. Therefore, developmental gait biomechanics might appear as a possible motor phenotype and biomarker, solid enough to be correlated to neuronal network maturation, in normal and atypical developmental trajectories-like in ASD.
    Language English
    Publishing date 2021-03-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2021.624522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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