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  1. Article: The genome sequence of common fleabane,

    Christenhusz, Maarten J M / Fay, Michael F

    Wellcome open research

    2023  Volume 8, Page(s) 447

    Abstract: We present a genome assembly from an ... ...

    Abstract We present a genome assembly from an individual
    Language English
    Publishing date 2023-10-12
    Publishing country England
    Document type Journal Article
    ISSN 2398-502X
    ISSN 2398-502X
    DOI 10.12688/wellcomeopenres.20003.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Orchid conservation: how can we meet the challenges in the twenty-first century?

    Fay, Michael F

    Botanical studies

    2018  Volume 59, Issue 1, Page(s) 16

    Abstract: With c. 28,000 species, orchids are one of the largest families of flowering plants, and they are also one of the most threatened, in part due to their complex life history strategies. Threats include habitat destruction and climate change, but many ... ...

    Abstract With c. 28,000 species, orchids are one of the largest families of flowering plants, and they are also one of the most threatened, in part due to their complex life history strategies. Threats include habitat destruction and climate change, but many orchids are also threatened by unsustainable (often illegal and/or undocumented) harvest for horticulture, food or medicine. The level of these threats now outstrips our abilities to combat them at a species-by-species basis for all species in such a large group as Orchidaceae; if we are to be successful in conserving orchids for the future, we will need to develop approaches that allow us to address the threats on a broader scale to complement focused approaches for the species that are identified as being at the highest risk.
    Language English
    Publishing date 2018-06-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2432110-2
    ISSN 1999-3110 ; 1817-406X
    ISSN (online) 1999-3110
    ISSN 1817-406X
    DOI 10.1186/s40529-018-0232-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: 1042. SORBUS ARIA: Rosaceae

    Fay, Michael F. / Rich, Tim C. G.

    Curtis's Botanical Magazine. 2022 Dec., v. 39, no. 4 p.655-668

    2022  

    Abstract: Sorbus aria, COMMON WHITEBEAM, is described and illustrated. It is morphologically and genetically variable, and numerous selected forms are planted. Notes on its role as a parent of hybridogenous species and its historical and potential use are provided. ...

    Abstract Sorbus aria, COMMON WHITEBEAM, is described and illustrated. It is morphologically and genetically variable, and numerous selected forms are planted. Notes on its role as a parent of hybridogenous species and its historical and potential use are provided.
    Keywords Sorbus aria ; parenting ; parents ; plant architecture
    Language English
    Dates of publication 2022-12
    Size p. 655-668.
    Publishing place Blackwell Publishing Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2006494-9
    ISSN 1467-8748 ; 1355-4905
    ISSN (online) 1467-8748
    ISSN 1355-4905
    DOI 10.1111/curt.12476
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Orchid conservation: further links.

    Fay, Michael F

    Annals of botany

    2016  Volume 118, Issue 1, Page(s) 89–91

    Abstract: Background: Due in great part to their often complex interactions with mycorrhizal fungi, pollinators and host trees, Orchidaceae present particular challenges for conservation. Furthermore, orchids, as potentially the largest family of angiosperms with ...

    Abstract Background: Due in great part to their often complex interactions with mycorrhizal fungi, pollinators and host trees, Orchidaceae present particular challenges for conservation. Furthermore, orchids, as potentially the largest family of angiosperms with >26000 species, species complexes and frequent hybrid formation, are complex to catalogue. Following a highlight in 2015, a further seven papers focusing on orchids, their interactions with beneficial organisms, pollinators and mycorrhiza, and other factors relating to their conservation, including threats from human utilization and changing land use, are presented here.
    Conclusions: The production of an online flora of all known plants and an assessment of the conservation status of all known plant species as far as possible, to guide conservation action are the first two targets of the Global Strategy for Plant Conservation Without knowing how many species there are and how they should be circumscribed, neither of these targets is achievable. Orchids are a fascinating subject for fundamental research with rapid species evolution, specific organ structure and development, but they also suffer from high levels of threat. Effective orchid conservation must take account of the beneficial interactions with fungi and pollinators and the potentially detrimental effects of over-collection and changes in land use.
    MeSH term(s) Mycorrhizae ; Orchidaceae ; Trees
    Language English
    Publishing date 2016-07-07
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 1461328-1
    ISSN 1095-8290 ; 0305-7364
    ISSN (online) 1095-8290
    ISSN 0305-7364
    DOI 10.1093/aob/mcw147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effective double-digest RAD sequencing and genotyping despite large genome size.

    Gargiulo, Roberta / Kull, Tiiu / Fay, Michael F

    Molecular ecology resources

    2021  Volume 21, Issue 4, Page(s) 1037–1055

    Abstract: Obtaining informative data is the ambition of any genomic project, but in nonmodel species with very large genomes, pursuing such a goal requires surmounting a series of analytical challenges. Double-digest RAD sequencing is routinely used in nonmodel ... ...

    Abstract Obtaining informative data is the ambition of any genomic project, but in nonmodel species with very large genomes, pursuing such a goal requires surmounting a series of analytical challenges. Double-digest RAD sequencing is routinely used in nonmodel organisms and offers some control over the volume of data obtained. However, the volume of data recovered is not always an indication of the reliability of data sets, and quality checks are necessary to ensure that true and artefactual information is set apart. In the present study, we aim to fill the gap existing between the known applicability of RAD sequencing methods in plants with large genomes and the use of the retrieved loci for population genetic inference. By analysing two populations of Cypripedium calceolus, a nonmodel orchid species with a large genome size (1C ~ 31.6 Gbp), we provide a complete workflow from library preparation to bioinformatic filtering and inference of genetic diversity and differentiation. We show how filtering strategies to dismiss potentially misleading data need to be explored and adapted to data set-specific features. Moreover, we suggest that the occurrence of organellar sequences in libraries should not be neglected when planning the experiment and analysing the results. Finally, we explain how, in the absence of prior information about the genome of the species, seeking high standards of quality during library preparation and sequencing can provide an insurance against unpredicted technical or biological constraints.
    MeSH term(s) Computational Biology ; Genome Size ; Genotype ; Orchidaceae/genetics ; Reproducibility of Results ; Sequence Analysis ; Sequence Analysis, DNA ; Workflow
    Language English
    Publishing date 2021-01-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2406833-0
    ISSN 1755-0998 ; 1755-098X
    ISSN (online) 1755-0998
    ISSN 1755-098X
    DOI 10.1111/1755-0998.13314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Upregulation of the Renin-Angiotensin System Is Associated with Patient Survival and the Tumour Microenvironment in Glioblastoma.

    Lozinski, Mathew / Lumbers, Eugenie R / Bowden, Nikola A / Martin, Jennifer H / Fay, Michael F / Pringle, Kirsty G / Tooney, Paul A

    Cells

    2024  Volume 13, Issue 7

    Abstract: Glioblastoma is a highly aggressive disease with poor survival outcomes. An emerging body of literature links the role of the renin-angiotensin system (RAS), well-known for its function in the cardiovascular system, to the progression of cancers. We ... ...

    Abstract Glioblastoma is a highly aggressive disease with poor survival outcomes. An emerging body of literature links the role of the renin-angiotensin system (RAS), well-known for its function in the cardiovascular system, to the progression of cancers. We studied the expression of RAS-related genes (
    MeSH term(s) Humans ; Renin-Angiotensin System/genetics ; Up-Regulation/genetics ; Glioblastoma/genetics ; Tumor Microenvironment ; Receptors, Cell Surface/metabolism ; Prorenin Receptor
    Chemical Substances Receptors, Cell Surface ; ATP6AP2 protein, human ; Prorenin Receptor
    Language English
    Publishing date 2024-04-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells13070634
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Orchid conservation: how can we meet the challenges in the twenty-first century?

    Fay, Michael F

    Botanical studies. 2018 Dec., v. 59, no. 1

    2018  

    Abstract: With c. 28,000 species, orchids are one of the largest families of flowering plants, and they are also one of the most threatened, in part due to their complex life history strategies. Threats include habitat destruction and climate change, but many ... ...

    Abstract With c. 28,000 species, orchids are one of the largest families of flowering plants, and they are also one of the most threatened, in part due to their complex life history strategies. Threats include habitat destruction and climate change, but many orchids are also threatened by unsustainable (often illegal and/or undocumented) harvest for horticulture, food or medicine. The level of these threats now outstrips our abilities to combat them at a species-by-species basis for all species in such a large group as Orchidaceae; if we are to be successful in conserving orchids for the future, we will need to develop approaches that allow us to address the threats on a broader scale to complement focused approaches for the species that are identified as being at the highest risk.
    Keywords Orchidaceae ; climate change ; habitat destruction ; horticulture ; life history ; medicine ; risk
    Language English
    Dates of publication 2018-12
    Size p. 16.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note Review
    ZDB-ID 2432110-2
    ISSN 1999-3110 ; 1817-406X
    ISSN (online) 1999-3110
    ISSN 1817-406X
    DOI 10.1186/s40529-018-0232-z
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  8. Article ; Online: 1045. SORBUS AVONENSIS: Rosaceae

    Houston, Libby / Rich, Tim C. G. / Barlow, Gillian / Brown, Andrew P. / Fay, Michael F.

    Curtis's Botanical Magazine. 2022 Dec., v. 39, no. 4 p.693-703

    2022  

    Abstract: Sorbus avonensis, AVON WHITEBEAM, is described and illustrated. It was originally treated as a triploid hybrid to cover plants of S. aria (diploid) × S. porrigentiformis (tetraploid) parentage, but after the discovery of more identical trees in 2014–2016, ...

    Abstract Sorbus avonensis, AVON WHITEBEAM, is described and illustrated. It was originally treated as a triploid hybrid to cover plants of S. aria (diploid) × S. porrigentiformis (tetraploid) parentage, but after the discovery of more identical trees in 2014–2016, it is now treated as a species. It is endemic to the Avon Gorge, England where a population of c. 47 trees is known.
    Keywords Sorbus ; diploidy ; hybrids ; parentage ; tetraploidy ; triploidy ; England
    Language English
    Dates of publication 2022-12
    Size p. 693-703.
    Publishing place Blackwell Publishing Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2006494-9
    ISSN 1467-8748 ; 1355-4905
    ISSN (online) 1467-8748
    ISSN 1355-4905
    DOI 10.1111/curt.12479
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  9. Article ; Online: 1044. SORBUS PORRIGENTIFORMIS: Rosaceae

    Rich, Tim C. G. / Barlow, Gillian / Brown, Andrew P. / Fay, Michael F.

    Curtis's Botanical Magazine. 2022 Dec., v. 39, no. 4 p.681-691

    2022  

    Abstract: Sorbus porrigentiformis, GREY‐LEAVED WHITEBEAM, is described and illustrated. It is a neoendemic with obovate leaves and fruits wider than long, and it is widespread in south‐west England and South Wales. It was originally broadly circumscribed, but it ... ...

    Abstract Sorbus porrigentiformis, GREY‐LEAVED WHITEBEAM, is described and illustrated. It is a neoendemic with obovate leaves and fruits wider than long, and it is widespread in south‐west England and South Wales. It was originally broadly circumscribed, but it has now been split into at least 11 constituent parts. It is a cornerstone species for Sorbus speciation in Britain. It may have originated from S. aria × S. rupicola or from an ancestral taxon in Central Europe.
    Keywords Sorbus ; Central European region ; England
    Language English
    Dates of publication 2022-12
    Size p. 681-691.
    Publishing place Blackwell Publishing Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2006494-9
    ISSN 1467-8748 ; 1355-4905
    ISSN (online) 1467-8748
    ISSN 1355-4905
    DOI 10.1111/curt.12478
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  10. Article ; Online: 1040. SORBUS AUCUPARIA: Rosaceae

    Fay, Michael F. / Barlow, Gillian / Brown, Andrew P. / Rich, Tim C. G.

    Curtis's Botanical Magazine. 2022 Dec., v. 39, no. 4 p.631-643

    2022  

    Abstract: Sorbus aucuparia subsp. aucuparia, ROWAN or MOUNTAIN ASH, is described and illustrated. Details of its distribution, genetic variability, cultural history and use by humans and animals are provided. ...

    Abstract Sorbus aucuparia subsp. aucuparia, ROWAN or MOUNTAIN ASH, is described and illustrated. Details of its distribution, genetic variability, cultural history and use by humans and animals are provided.
    Keywords Sorbus aucuparia ; genetic variation ; humans
    Language English
    Dates of publication 2022-12
    Size p. 631-643.
    Publishing place Blackwell Publishing Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 2006494-9
    ISSN 1467-8748 ; 1355-4905
    ISSN (online) 1467-8748
    ISSN 1355-4905
    DOI 10.1111/curt.12474
    Database NAL-Catalogue (AGRICOLA)

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