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  1. Article ; Online: The development and cognitive testing of a patient-reported experience measure for patients with chronic pain of temporomandibular disorders.

    Taimeh, Dina / Ni Riordain, Richeal / Fedele, Stefano / Leeson, Rachel

    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology

    2023  Volume 52, Issue 9, Page(s) 843–848

    Abstract: Introduction: The importance of the patients' clinical experience has been reinforced several times over the last decade by healthcare organisations and policy makers. Routine gathering of experience data can help in enhancing patient-centred care and ... ...

    Abstract Introduction: The importance of the patients' clinical experience has been reinforced several times over the last decade by healthcare organisations and policy makers. Routine gathering of experience data can help in enhancing patient-centred care and provide guidance to quality improvement schemes. Patient-reported experience measures can help to that end. The aim of this study was to develop a patient-reported experience measure to evaluate the experience of patients with temporomandibular disorders while receiving healthcare.
    Methods: Input from several sources was utilised to develop the tool; previous literature, patients with temporomandibular disorders, and experts in the field. A qualitative study was conducted following the COnsensus-based Standards for the selection of health Measurement Instruments guidance to generate the items of the questionnaire, which subsequently underwent cognitive testing.
    Results: Seventeen patients took part in the qualitative study, in addition to six healthcare professionals. The preliminary questionnaire consisted of 28 questions with six response options.
    Conclusions: This patient-reported experience measure is a brief tool to evaluate the clinical experience of patients with temporomandibular disorders. Patients' involvement ensured face and content validity of the questionnaire, in addition to the relevance, comprehensibility and comprehensiveness of the items.
    MeSH term(s) Humans ; Chronic Pain/diagnosis ; Patient Reported Outcome Measures ; Surveys and Questionnaires ; Qualitative Research ; Temporomandibular Joint Disorders/complications ; Temporomandibular Joint Disorders/diagnosis ; Reproducibility of Results
    Language English
    Publishing date 2023-07-05
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1021270-x
    ISSN 1600-0714 ; 0904-2512
    ISSN (online) 1600-0714
    ISSN 0904-2512
    DOI 10.1111/jop.13462
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Meta-Synthesis of the Experience of Chronic Temporomandibular Disorder Patients Within Health Care Services

    Taimeh, Dina / Leeson, Rachel / Fedele, Stefano / Riordain, Richeal Ni

    Journal of oral & facial pain and headache

    2023  Volume 37, Issue 1, Page(s) 55–73

    Abstract: Aims: ...

    Abstract Aims:
    MeSH term(s) Humans ; Delivery of Health Care ; Health Services ; Qualitative Research ; Social Support ; Temporomandibular Joint Disorders/diagnosis ; Temporomandibular Joint Disorders/psychology ; Temporomandibular Joint Disorders/therapy ; Patient Acceptance of Health Care ; Chronic Disease ; Physician-Patient Relations ; Clinical Competence ; Motivation
    Language English
    Publishing date 2023-03-14
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2762048-7
    ISSN 2333-0376 ; 2333-0384
    ISSN (online) 2333-0376
    ISSN 2333-0384
    DOI 10.11607/ofph.3112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Healthcare priorities in patients with chronic facial pain of temporomandibular disorders.

    Taimeh, Dina / Riordain, Richeal Ni / Fedele, Stefano / Leeson, Rachel

    Oral diseases

    2023  Volume 29, Issue 7, Page(s) 2878–2887

    Abstract: Objectives: To explore the experiences of patients with temporomandibular disorders (TMDs) with the National Health Service and to discover their healthcare priorities when seeking treatment.: Methods: Semi-structured interviews were used. They were ... ...

    Abstract Objectives: To explore the experiences of patients with temporomandibular disorders (TMDs) with the National Health Service and to discover their healthcare priorities when seeking treatment.
    Methods: Semi-structured interviews were used. They were directed using a topic guide covering subjects such as initial visits in primary care, referrals to secondary care, and the effect on symptoms. The discussions were audiotaped and transcribed verbatim. Thematic analysis was utilised to analyse the data.
    Results: In total, 15 participants took part in three focus groups. Six themes were identified: "access to appropriate care", "organised and coordinated care", "receiving a diagnosis and enough information", "interaction with the clinical staff", "treatment strategies and having an 'action plan'" and "support and social networks".
    Conclusions: The participants gave accounts of the difficulties encountered in healthcare in general terms and specific to TMD. Most notable was the struggle to access appropriate care, receive a diagnosis and be understood. Our findings suggest that delays in delivering appointments with people of expertise may have caused the worsening of symptoms. However, when a pleasant experience was encountered, access to care was fast, the clinician was understanding and communication with the clinical team was good. These provided positive experiences and were appreciated by the patients.
    MeSH term(s) Humans ; State Medicine ; Delivery of Health Care ; Facial Pain/etiology ; Facial Pain/therapy ; Temporomandibular Joint Disorders/complications ; Temporomandibular Joint Disorders/therapy ; Chronic Pain/therapy
    Language English
    Publishing date 2023-01-13
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14483
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Patient and clinician perspectives of information needs concerning oral epithelial dysplasia.

    Alsoghier, Abdullah / Riordain, Richeal Ni / Fedele, Stefano / Porter, Stephen

    Oral diseases

    2023  

    Abstract: Objectives: Individuals diagnosed with a chronic oral disease that increase the risk of mouth cancer, such as oral epithelial dysplasia (OED), require appropriate knowledge to make informed decisions. The present study aimed to assess whether patient ... ...

    Abstract Objectives: Individuals diagnosed with a chronic oral disease that increase the risk of mouth cancer, such as oral epithelial dysplasia (OED), require appropriate knowledge to make informed decisions. The present study aimed to assess whether patient information needs of a group of patients concerning dysplasia were met and to what degree clinicians agree with patients on 'important' topics.
    Subjects and methods: This represented secondary analyses of a cross-sectional study to assess the information needs of 86 patients diagnosed with dysplasia compared with those of 77 clinicians using the validated OED Information Needs Questionnaire. Descriptive, concordance and regression analyses were performed for the collected data.
    Results: The mean and median total scores for all items in the amount of information received subscale were 2.33 and 2.44, indicating overall unmet needs concerning dysplasia. Clinicians were generally able to predict topics of greatest importance to patients, although their scores were mainly lower than those of patients (k = 0.06). There was a higher agreement between patients (k = 0.25) than clinicians (k = 0.09).
    Conclusion: Clinicians are encouraged to assess a patient's information needs to ensure tailored and patient-centred communication concerning OED during all clinical consultations.
    Language English
    Publishing date 2023-07-16
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14668
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  5. Article ; Online: Patient-Reported Outcome Measures Used in Temporomandibular Disorders: A Review of the Literature.

    Taimeh, Dina / Ni Riordain, Richeal / Fedele, Stefano / Leeson, Rachel

    Journal of oral & facial pain and headache

    2023  Volume 37, Issue 2, Page(s) 113–129

    Abstract: Aims: To identify the range of patient-reported outcome measures (PROMs) used in TMD studies, summarize the available evidence for their psychometric properties, and provide guidance for the selection of such measures.: Methods: A comprehensive ... ...

    Abstract Aims: To identify the range of patient-reported outcome measures (PROMs) used in TMD studies, summarize the available evidence for their psychometric properties, and provide guidance for the selection of such measures.
    Methods: A comprehensive search was conducted to retrieve articles published between 2009 and 2018 containing a patient-reported measure of the effects of TMDs. Three databases were searched: MEDLINE, Embase, and Web of Science.
    Results: A total of 517 articles containing at least one PROM were included in the review, and 57 additional studies were also located describing the psychometric properties of some tools in a TMD population. A total of 106 PROMs were identified and fell into the following categories: PROMs describing the severity of symptoms; PROMs describing psychologic status; and PROMs describing quality of life and general health. The most commonly used PROM was the visual analog scale. However, a wide range of verbal descriptors was employed. The Oral Health Impact Profile-14 and Beck Depression Inventory were the most commonly used PROMs describing the effect of TMDs on quality of life and psychologic status, respectively. Additionally, the Oral Health Impact Profile (various versions) and the Research Diagnostic Criteria Axis ll questionnaires were the instruments most repeatedly tested in a TMD population, and these instruments have undergone cross-cultural validation in several languages.
    Conclusion: A wide range of PROMs have been used to describe the impact of TMDs on patients. Such variability may limit the ability of researchers and clinicians to evaluate the efficacy of different treatments and make meaningful comparisons.
    MeSH term(s) Humans ; Quality of Life ; Temporomandibular Joint Disorders/therapy ; Databases, Factual ; Language ; Patient Reported Outcome Measures
    Language English
    Publishing date 2023-06-27
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 2762048-7
    ISSN 2333-0376 ; 2333-0384
    ISSN (online) 2333-0376
    ISSN 2333-0384
    DOI 10.11607/ofph.3264
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  6. Article ; Online: Audiovisual information of oral epithelial dysplasia: Quality, understandability and actionability.

    Alamoudi, Waleed / Riordain, Richeal Ni / Fedele, Stefano / Porter, Stephen

    Oral diseases

    2023  

    Abstract: Objectives: Online information on oral epithelial dysplasia (OED) is insufficient and of low quality. While only written information has been previously assessed, this study aims to evaluate the content and quality of audiovisual (AV) online information ...

    Abstract Objectives: Online information on oral epithelial dysplasia (OED) is insufficient and of low quality. While only written information has been previously assessed, this study aims to evaluate the content and quality of audiovisual (AV) online information about OED.
    Methods: One hundred and twenty-seven materials were initially considered using six key words across two search engines (YouTube and Google). Ultimately, 29 materials remained for the final assessment. These materials were then analysed for content, quality (DISCERN instrument, JAMA benchmarks), understandability and actionability.
    Results: Most contents were scientific (n = 25), while three videos were educational, and one video was a personal experience with OED. On a scale of 1-5, the overall DISCERN score was (mean ± SD = 2.26 ± 0.79), suggesting poor quality of information. Regarding JAMA benchmarks, there was no single material that fulfilled or lacked all four benchmarks. The overall mean understandability score was 82% and the actionability mean score was significantly low at 29%.
    Conclusion: Although the vast majority of AV materials on OED were primarily produced for scientific purposes, these materials could be helpful as resources for patient education. Keeping in mind, however, that the desired quality and essential patient information about OED available online remains largely poor and missing.
    Language English
    Publishing date 2023-07-30
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14701
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Validity and internal consistency of four scales in patients with TMD: PHQ8, GAD7, PHQ15 and JFLS20.

    Taimeh, Dina / Riordain, Richeal Ni / Fedele, Stefano / Leeson, Rachel

    Oral diseases

    2023  

    Abstract: Objectives: The aim of this cross-sectional study was to explore the structural validity and internal consistency reliability of General Anxiety Disorder-7, Patient Health Questionnaire-8, 15 and Jaw Functional Limitation Scale-20 in patients with ... ...

    Abstract Objectives: The aim of this cross-sectional study was to explore the structural validity and internal consistency reliability of General Anxiety Disorder-7, Patient Health Questionnaire-8, 15 and Jaw Functional Limitation Scale-20 in patients with chronic pain of temporomandibular disorders.
    Materials and methods: Validity and reliability were assessed in 129 patients diagnosed according to the diagnostic criteria for temporomandibular disorders. Structural validity was explored using factor analysis, and internal consistency by calculating Cronbach α.
    Results: Confirmatory factor analysis revealed a suitable 2-factor model for Patient Health Questionnaire-8, with Cronbach α of 0.89, and 0.86. One and 2-factor models were suitable for General Anxiety Disorder-7, with overall Cronbach α of 0.93 for the 1-factor model, and 0.91 and 0.84 for both factors in a 2-factor model. A 4-factor solution was appropriate for Patient Health Questionnaire-15, with Cronbach α of 0.72, 0.57, 0.71 and 0.73 for each factor separately. Exploratory factor analysis was conducted to explore the factor structure of Jaw Functional Limitation Scale 20, and a 3-factor solution was appropriate.
    Conclusions: This study provides positive evidence of structural validity and internal consistency of these questionnaires in patients with pain of temporomandibular disorders. However, additional testing is required to explore further psychometric properties.
    Language English
    Publishing date 2023-10-05
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.14729
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  8. Article ; Online: My tongue hurts.

    Porter, Stephen / Escudier, Michael / Fedele, Stefano

    British dental journal

    2022  Volume 233, Issue 7, Page(s) 547–549

    Abstract: This series of articles comprise of short reviews of clinical problems relevant to oral health care in the twenty-first century. The present article uses a composite of presenting case symptoms to hypothetically illustrate differential diagnoses of pain ... ...

    Abstract This series of articles comprise of short reviews of clinical problems relevant to oral health care in the twenty-first century. The present article uses a composite of presenting case symptoms to hypothetically illustrate differential diagnoses of pain of the tongue and why there may, or may not be, links to aspects of infection of SARS-CoV-2 (COVID-19).
    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Tongue
    Language English
    Publishing date 2022-10-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 218090-x
    ISSN 1476-5373 ; 0007-0610
    ISSN (online) 1476-5373
    ISSN 0007-0610
    DOI 10.1038/s41415-022-5026-8
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  9. Article ; Online: COVID-19 NHS infection control strategy: Errare humanum est, perseverare autem diabolicum.

    Fedele, Stefano / Porter, Stephen

    Oral diseases

    2020  Volume 28 Suppl 1, Page(s) 849–851

    Keywords covid19
    Language English
    Publishing date 2020-11-07
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.13605
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  10. Article: Early-Phase Interventional Trials in Oral Cancer Prevention.

    McCarthy, Caroline / Fedele, Stefano / Ottensmeier, Christian / Shaw, Richard J

    Cancers

    2021  Volume 13, Issue 15

    Abstract: The increasing breadth of molecular targets, promise of immune-targeted therapies and repurposed agents have heightened interest in cancer prevention. While, to date, testing of oral cancer chemoprevention strategies has failed to deliver therapeutic ... ...

    Abstract The increasing breadth of molecular targets, promise of immune-targeted therapies and repurposed agents have heightened interest in cancer prevention. While, to date, testing of oral cancer chemoprevention strategies has failed to deliver therapeutic agents for routine clinical practice, there remains an urgent need for further clinical research to overcome this hurdle. Patients at the greatest risk of disease stand to benefit the most from inclusion in clinical trials; therefore, there is a need to carefully define this population using validated clinical and molecular markers. Safety, tolerability and the efficacy of interventions is assessed through carefully selected endpoints. These endpoints may include pharmacodynamic, clinical, histological and on-target molecular modifications as an individual or as a composite endpoint. Early-phase trials provide an area of opportunity to explore novel and repurposed agents in the setting of oral cancer chemoprevention, eventually leading to phase III trials with clinical endpoints such as transformation and clinical outcome; these studies are large, lengthy and expensive and should be reserved for the most promising of agents. This paper will explore current evidence in oral cancer chemoprevention, drug repurposing, selection of appropriate endpoints for early-phase trials and novel therapeutic angles in oral cancer chemoprevention.
    Language English
    Publishing date 2021-07-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers13153845
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