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  1. Article ; Online: Rapid progression after ibrutinib discontinuation in a patient with mantle cell lymphoma who has severe coronavirus disease 2019 infection

    Fehmi Hindilerden / İpek Yönal Hindilerden / Reyhan Diz Küçükkaya

    Balkan Medical Journal, Vol 38, Iss 2, Pp 141-

    2021  Volume 142

    Keywords Medicine ; R
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Galenos Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Immune Thrombocytopenia in a Very Elderly Patient With Covid-19

    Fehmi Hindilerden / Ipek Yonal-Hindilerden / Senoglu Sevtap / Kadriye Kart-Yasar

    Frontiers in Medicine, Vol

    2020  Volume 7

    Abstract: Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a decreased number of platelets and mucocutaneous bleeding. Many viruses have been identified as triggers of the autoimmune process, including human immunodeficiency virus (HIV), ... ...

    Abstract Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by a decreased number of platelets and mucocutaneous bleeding. Many viruses have been identified as triggers of the autoimmune process, including human immunodeficiency virus (HIV), hepatitis C virus (HCV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), parvovirus, rubella, and measles. Association with the new severe acute respiratory syndrome coronavirus, SARS-CoV-2 infection (Covid-19 infection) has been rarely reported. Here, we report the oldest case of ITP patient triggered by the novel coronavirus infection. He showed inadequate response to IVIG but responded to corticosteroids with no severe adverse events. Further studies are warranted to determine the optimal therapeutic strategies for ITP with the Covid-19 infection.
    Keywords immune thrombocytopenia ; Covid-19 ; very old age ; intravenous immunoglobulin ; corticosteroids ; Medicine (General) ; R5-920 ; covid19
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Severe autoimmune hemolytic anemia in Covid-19 infection

    Fehmi Hindilerden / Ipek Yonal-Hindilerden / Emre Akar / Zuhal Yesilbag / Kadriye Kart-Yasar

    Mediterranean Journal of Hematology and Infectious Diseases, Vol 12, Iss

    2020  Volume 1

    Abstract: ... ...

    Abstract xx
    Keywords Autoimmune hemolytic anemia ; Covid-19 ; corticosteroids ; Diseases of the blood and blood-forming organs ; RC633-647.5 ; covid19
    Language English
    Publishing date 2020-06-01T00:00:00Z
    Publisher PAGEPress Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Primary Mediastinal Large B-Cell Lymphoma As an Incidental Finding

    İpek Yönal Hindilerden / Fehmi Hindilerden / Serkan Arslan / Öner İbrahim Doğan / Meliha Nalçacı

    Turkish Journal of Hematology, Vol 35, Iss 2, Pp 141-

    Report of a Case

    2018  Volume 142

    Keywords Mediastinal neoplasm ; B-cell lymphoma ; PMBCL ; Internal medicine ; RC31-1245 ; Diseases of the blood and blood-forming organs ; RC633-647.5
    Language English
    Publishing date 2018-05-01T00:00:00Z
    Publisher Galenos Yayinevi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Hairy cell leukemia followed by polycythemia vera: report of the first case.

    Ipek, Yonal-Hindilerden / Fehmi, Hindilerden / Meliha, Nalcaci

    Oxford medical case reports

    2016  Volume 2016, Issue 3, Page(s) 28–30

    Language English
    Publishing date 2016-03-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2766251-2
    ISSN 2053-8855
    ISSN 2053-8855
    DOI 10.1093/omcr/omw005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Rituximab Therapy in Adults with Refractory Symptomatic Immune Thrombocytopenia

    Fehmi Hindilerden / Ipek Yönal Hindilerden / Mustafa Nuri Yenerel / Meliha Nalçacı / Reyhan Diz Küçükkaya

    Turkish Journal of Hematology, Vol 34, Iss 1, Pp 72-

    Long-Term Follow-Up of 15 Cases

    2017  Volume 80

    Abstract: Objective: This paper prospectively evaluates the long-term followup [mean ± standard deviation (SD) duration: 89.7±19.4 months] data of 15 patients (13 females and 2 males) with refractory symptomatic immune thrombocytopenia (ITP) treated with rituximab. ...

    Abstract Objective: This paper prospectively evaluates the long-term followup [mean ± standard deviation (SD) duration: 89.7±19.4 months] data of 15 patients (13 females and 2 males) with refractory symptomatic immune thrombocytopenia (ITP) treated with rituximab. Materials and Methods: Rituximab was administered at 375 mg/m2 weekly for a total of 4 doses. Complete response (CR) was defined as a platelet count of ≥100,000/mm3 and partial response (PR) as a platelet count of ≥30,000/mm3 but less than 100,000/mm3. Early response (ER) and late response (LR) were defined as response within 42 days and after 42 days of initiation of rituximab therapy, respectively. Sustained response (SR) was defined as response lasting for at least 6 months. Results: Mean age (±SD) at the start of rituximab was 46.6±11.3 years. Mean platelet count (±SD) prior to rituximab treatment was 17,400±8878/mm3. The mean time (±SD) between rituximab therapy and response to rituximab in early responders and late responders was 1.8±1.3 weeks and 10±2.8 weeks, respectively. Mean durations (±SD) of ER and LR were 51±47.2 months and 6±4.2 months, respectively. Seven of the 15 patients (46.7%) showed an initial response to rituximab (5 ER and 2 LR). The rate of SR over 6 months was 26.7% (4/15). Among the responders to rituximab, 3 (3/7, 42.9%) maintained their response 1 year after rituximab treatment and 2 (2/7, 28.6%) had ongoing response 5 years after initiation of rituximab. Two of the 7 patients (28.6%) still maintained their response 98 months after initiation of rituximab. All 5 initial responders with subsequent relapse achieved response from subsequent treatment modalities (3 CR, 2 PR). Conclusion: Our data confirm, over a long period of observation, that rituximab is safe and effective in the management of patients with chronic refractory primary ITP.
    Keywords Immune thrombocytopenia ; Rituximab ; Early response ; Late response ; Sustained response ; Internal medicine ; RC31-1245 ; Diseases of the blood and blood-forming organs ; RC633-647.5
    Subject code 610
    Language English
    Publishing date 2017-03-01T00:00:00Z
    Publisher Galenos Yayinevi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: A Rare Cause of Unexplained Refractory Iron Deficiency Anemia

    Sevgi Kalayoğlu Beşışık / İpek Yönal Hindilerden / Fehmi Hindilerden / İbrahim Öner Doğan / Fatih Beşışık

    Turkish Journal of Hematology, Vol 33, Iss 3, Pp 257-

    Unicentric Plasma-Cell Type Castleman’s Disease

    2016  Volume 258

    Keywords Iron deficiency anemia ; Unicentric plasma-cell type ; Castleman’s disease ; Internal medicine ; RC31-1245 ; Diseases of the blood and blood-forming organs ; RC633-647.5
    Language English
    Publishing date 2016-08-01T00:00:00Z
    Publisher Galenos Yayinevi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Effects of Mutational Combinations on Philadelphia-Negative Myeloproliferative Neoplasms.

    Ipek, Yonal-Hindilerden / Aynur, Daglar-Aday / Fehmi, Hindilerden / Meliha, Nalcaci / Selim, Yavuz Akif / Deniz, Sargin

    Iranian journal of medical sciences

    2017  Volume 42, Issue 2, Page(s) 219–220

    Language English
    Publishing date 2017-03-30
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 603872-4
    ISSN 1735-3688 ; 0253-0716
    ISSN (online) 1735-3688
    ISSN 0253-0716
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1634: Show issues Location:
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  9. Article ; Online: Thrombotic complications in multiple myeloma: a report of three cases and review of the literature.

    Ipek, Yonal / Fehmi, Hindilerden / Sevgi, Besisik-Kalayoglu / Deniz, Sargin

    Journal of thrombosis and thrombolysis

    2011  Volume 33, Issue 2, Page(s) 197–201

    Abstract: The risk of venous thromboembolism (VTE) increases in the presence of plasma cell dyscrasias. Monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) share an intrinsic increased risk of VTE. Treatment with thalidomide and ... ...

    Abstract The risk of venous thromboembolism (VTE) increases in the presence of plasma cell dyscrasias. Monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) share an intrinsic increased risk of VTE. Treatment with thalidomide and lenalidomide further increases the incidence of VTE in certain MM patient subsets. The pathogenesis remains unclear, but probably involves several factors such as activation of procoagulant factors, acquired activated protein C resistance, and inflammation. In addition to general risk factors for VTE, such as older age, immobility, surgery, and inherited thrombophilia, there are some MM-specific and treatment-related factors that contribute to the increased risk. The risk for VTE is high under treatment with thalidomide or lenalidomide in combination with dexamethasone or multi-agent chemotherapy. We report 3 cases of MM with VTE with review of the literature. This review highlights the risk factors for VTE in MM and general, disease-specific and treatment-related mechanisms for thrombosis.
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Humans ; Male ; Middle Aged ; Multiple Myeloma/complications ; Multiple Myeloma/diagnosis ; Multiple Myeloma/drug therapy ; Venous Thrombosis/chemically induced ; Venous Thrombosis/diagnosis ; Venous Thrombosis/etiology
    Language English
    Publishing date 2011-09-09
    Publishing country Netherlands
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1230645-9
    ISSN 1573-742X ; 0929-5305
    ISSN (online) 1573-742X
    ISSN 0929-5305
    DOI 10.1007/s11239-011-0636-z
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4352: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: The Causes of Acute Fever Requiring Hospitalization in Geriatric Patients

    A. Atahan Cagatay / Fatih Tufan / Fehmi Hindilerden / Sibel Aydin / Omer Celal Elcioglu / Asli Karadeniz / Nilufer Alpay / Suut Gokturk / Ozer Taranoglu

    Journal of Aging Research, Vol

    Comparison of Infectious and NoninfectiousEtiology

    2010  Volume 2010

    Abstract: Introduction. Infectious diseases may present with atypical presentations in the geriatric patients. While fever is an important finding of infections, it may also be a sign of noninfectious etiology. Methods. Geriatric patients who were hospitalized for ...

    Abstract Introduction. Infectious diseases may present with atypical presentations in the geriatric patients. While fever is an important finding of infections, it may also be a sign of noninfectious etiology. Methods. Geriatric patients who were hospitalized for acute fever in our infectious diseases unit were included. Acute fever was defined as presentation within the first week of fever above 37.3∘C. Results. 185 patients were included (82 males and 103 females). Mean age was 69.7±7.5 years. The cause of fever was an infectious disease in 135 and noninfectious disease in 32 and unknown in 18 of the patients. The most common infectious etiologies were respiratory tract infections (n=46), urinary tract infections (n=26), and skin and soft tissue infections (n=23). Noninfectious causes of fever were rheumatic diseases (n=8), solid tumors (n=7), hematological diseases (n=10), and vasculitis (n=7). A noninfectious cause of fever was present in one patient with no underlying diseases and in 31 of 130 patients with underlying diseases. Conclusion. Geriatric patients with no underlying diseases generally had infectious causes of fever while noninfectious causes were responsible from fever in an important proportion of patients with underlying diseases.
    Keywords Geriatrics ; RC952-954.6 ; Special situations and conditions ; RC952-1245 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Internal medicine ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2010-01-01T00:00:00Z
    Publisher SAGE-Hindawi Access to Research
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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