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Article ; Online: Artificial intelligence in renal pathology

Chunyue Feng / Fei Liu

Bosnian Journal of Basic Medical Sciences (2022)

Current status and future

2022

Abstract: Renal biopsy pathology is an essential gold standard for the diagnosis of most kidney diseases. With the increase in the incidence rate of kidney diseases, the lack of renal pathologists, and an imbalance in their distribution, there is an urgent need ... ...

Abstract	Renal biopsy pathology is an essential gold standard for the diagnosis of most kidney diseases. With the increase in the incidence rate of kidney diseases, the lack of renal pathologists, and an imbalance in their distribution, there is an urgent need for a new renal pathological diagnosis model. Advances in artificial intelligence (AI) along with the growing digitization of pathology slides for diagnosis are promising approach to meet the demand for more accurate detection, classification, and prediction of the outcome of renal pathology. AI has contributed substantially to a variety of clinical applications, including renal pathology. Deep learning, a subfield of AI that is highly flexible and supports automatic feature extraction, is increasingly being used in multiple areas of pathology. In this narrative review, we first provide a general description of AI methods, and then discuss the current and prospective applications of AI in the field of renal pathology. Both diagnostic and predictive prognostic applications are covered, emphasizing AI in renal pathology images, predictive models, and 3D in renal pathology. Finally, we outline the challenges associated with the implementation of AI platforms in renal pathology and provide our perspective on how these platforms might change in this field.
Keywords	Artificial intelligence ; deep learning ; digital pathology ; nephropathology ; image analysis ; convolutional neural networks ; Medicine (General) ; R5-920
Subject code	006
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Closed-Form Sum-Rate Analysis of Interference Alignment with Limited Feedback Based on Scalar Quantization and Random Vector Quantization

Long Suo / Fei Liu

Applied Sciences, Vol 12, Iss 6117, p

2022 Volume 6117

Abstract: Interference alignment (IA) is a promising interference management technique to achieve the theoretical optimal degree of freedom (DoF) performance in multi-user cooperation scenarios. However, the effective achievable sum-rate performance of IA is ... ...

Abstract	Interference alignment (IA) is a promising interference management technique to achieve the theoretical optimal degree of freedom (DoF) performance in multi-user cooperation scenarios. However, the effective achievable sum-rate performance of IA is largely affected by the feedback overhead and accuracy of channel state information (CSI) and decoding information (DI). Therefore, it is critical to establish the exact relationship between feedback overhead and the achievable sum-rate of IA to obtain the optimal effective performance. Most existing IA performance analysis approaches focus on the vector quantization (VQ)-based feedback strategy, but the implementation complexity of VQ will be excessive when more quantization bits are required to achieve the expected quantization accuracy for larger-sized matrices or higher signal-to-noise ratio (SNR) regimes. Moreover, the obtained achievable sum-rate formulas are too complicated for quick performance evaluation. In this paper, a new sum-rate performance analysis method for IA under different quantization and feedback strategies is proposed to achieve a trade-off between accuracy and complexity, and the closed-form achievable sum-rate expressions are derived. First, in the IA case with random vector quantization (RVQ)-based CSI feedback, the quantization error of RVQ is transformed into the equivalent VQ error of the Gaussian channel error, based on which the achievable sum-rate formula is obtained. Second, in the IA case with scalar quantization (SQ)-based CSI feedback, the relationship between the effective sum-rate and SQ bits is established. Third, in the IA case with SQ-based CSI feedback and RVQ-based DI feedback, the achievable sum-rate formula is derived by combining these two kinds of quantization errors. Finally, the simulation results confirm that the theoretical results are accurate enough, which can help to determine the optimal CSI feedback overhead in practical channel conditions. Moreover, the theoretical and simulation results demonstrate that RVQ ...
Keywords	interference alignment ; sum-rate ; limited feedback ; random vector quantization ; scalar quantization ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	003
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Non-coding RNAs in skin cancers:Biological roles and molecular mechanisms

Fei Liu / Shenglong Li

Frontiers in Pharmacology, Vol

2022 Volume 13

Abstract: Cutaneous malignancies, including basal cell carcinoma, cutaneous squamous cell carcinoma, and cutaneous melanoma, are common human tumors. The incidence of cutaneous malignancies is increasing worldwide, and the leading cause of death is malignant ... ...

Abstract	Cutaneous malignancies, including basal cell carcinoma, cutaneous squamous cell carcinoma, and cutaneous melanoma, are common human tumors. The incidence of cutaneous malignancies is increasing worldwide, and the leading cause of death is malignant invasion and metastasis. The molecular biology of oncogenes has drawn researchers’ attention because of the potential for targeted therapies. Noncoding RNAs, including microRNAs, long noncoding RNAs, and circular RNAs, have been studied extensively in recent years. This review summarizes the aspects of noncoding RNAs related to the metastasis mechanism of skin malignancies. Continuous research may facilitate the identification of new therapeutic targets and help elucidate the mechanism of tumor metastasis, thus providing new opportunities to improve the survival rate of patients with skin malignancies.
Keywords	skin cancers ; non-coding RNA ; malignant progression ; molecular biology ; metastasis ; Therapeutics. Pharmacology ; RM1-950
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Animal models of pulmonary hypertension due to left heart disease

Shao‐Fei Liu / Yi Yan

Animal Models and Experimental Medicine, Vol 5, Iss 3, Pp 197-

2022 Volume 206

Abstract: Abstract Pulmonary hypertension due to left heart disease (PH‐LHD) is regarded as the most prevalent form of pulmonary hypertension (PH). Indeed, PH is an independent risk factor and predicts adverse prognosis for patients with left heart disease (LHD). ... ...

Abstract	Abstract Pulmonary hypertension due to left heart disease (PH‐LHD) is regarded as the most prevalent form of pulmonary hypertension (PH). Indeed, PH is an independent risk factor and predicts adverse prognosis for patients with left heart disease (LHD). Clinically, there are no drugs or treatments that directly address PH‐LHD, and treatment of LHD alone will not also ameliorate PH. To target the underlying physiopathological alterations of PH‐LHD and to develop novel therapeutic approaches for this population, animal models that simulate the pathophysiology of PH‐LHD are required. There are several available models for PH‐LHD that have been successfully employed in rodents or large animals by artificially provoking an elevated pressure load on the left heart, which by transduction elicits an escalated pressure in pulmonary artery. In addition, metabolic derangement combined with aortic banding or vascular endothelial growth factor receptor antagonist is also currently applied to reproduce the phenotype of PH‐LHD. As of today, none of the animal models exactly recapitulates the condition of patients with PH‐LHD. Nevertheless, the selection of an appropriate animal model is essential in basic and translational studies of PH‐LHD. Therefore, this review will summarize the characteristics of each PH‐LHD animal model and discuss the advantages and limitations of the different models.
Keywords	animal model ; left ventricular failure ; metabolic syndrome ; pulmonary hypertension due to left heart disease ; pulmonary vascular remodeling ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Determinants of international football performance

Mu Fan / Fei Liu / Dong Huang / Hui Zhang

Heliyon, Vol 9, Iss 10, Pp e20252- (2023)

Empirical evidence from the 1994–2022 FIFA World Cup

2023

Abstract: In the past 30 years, the global influence of the FIFA World Cup has continued to grow. According to statistics, the final match of the 2022 World Cup in Qatar attracted an audience of over 3 billion. Nowadays, nations (and regions) emphasize the ... ...

Abstract	In the past 30 years, the global influence of the FIFA World Cup has continued to grow. According to statistics, the final match of the 2022 World Cup in Qatar attracted an audience of over 3 billion. Nowadays, nations (and regions) emphasize the correlation between overall social progress, football tradition, and national sporting prowess. This study aims to comprehend the dynamics of international football development and secure a competitive edge in the global arena. The study collected panel data from 68 countries (regions) participating in the final stage of the World Cup from 1994 to 2022. It modelled them using a generalized linear mixed model (GLMM) to reveal the macro determinants of success and winning patterns in international football performance. The findings show that (1) football tradition's “characteristic values” (e.g. World Cup host, the experience of hosting the World Cup and the number of all-time World Cup winners) and national comprehensive sporting strength (as represented by the Olympic Games results) have significantly contributed to the national team's World Cup performance; (2) the country's Human Development Index (HDI) has a significant negative impact on World Cup performance; (3) the history of football participation (e.g. the number of years of membership in the Intercontinental Football Association (IFA), history of professional leagues) will have little impact on World Cup performance; (4) two interactive variables: population scale × national comprehensive sporting strength (GPOP × CSOGMedals) and economic level × football tradition (lnGDP × PLHistory), have a negative and positive combined effect on World Cup performance, respectively.
Keywords	World cup ; Football performance ; Macro factors ; Generalized linear mixed model ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	796
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Phase Inversion Mechanism of the pH-Sensitive Reversible Invert Emulsion

Fei Liu / Yongfei Li / Xiaqing Li / Xuewu Wang

Molecules, Vol 28, Iss 21, p

2023 Volume 7407

Abstract: Reversible emulsification drilling fluids can achieve conversion between oil-based drilling fluids and water-based drilling fluids at different stages of drilling and completion, combining the advantages of both to achieve the desired drilling and ... ...

Abstract	Reversible emulsification drilling fluids can achieve conversion between oil-based drilling fluids and water-based drilling fluids at different stages of drilling and completion, combining the advantages of both to achieve the desired drilling and completion effects. The foundation of reversible emulsion drilling fluids lies in reversible emulsions, and the core of a reversible emulsion is the reversible emulsifier. In this study, we prepared a reversible emulsifier, DMOB( N , N -dimethyl- N ′-oleic acid-1,4-butanediamine), and investigated the reversible phase inversion process of reversible emulsions, including the changes in the reversible emulsifier (HLB) and its distribution at the oil–water interface (zeta potential). From the perspective of the acid–alkali response mechanism of reversible emulsifiers, we explored the reversible phase inversion mechanism of reversible emulsions and reversible emulsification drilling fluids. It was revealed that the reversible phase inversion of emulsions could be achieved by adjusting the pH of the emulsion system. Then the proportion of ionic surfactants changed in the oil–water interface and subsequently raised/lowered the HLB value of the composite emulsifier at the oil–water interface, leading to reversible phase inversion of the emulsion. The introduction of organic clays into reversible emulsification drilling fluid can affect the reversible conversion performance of the drilling fluids at the oil–water interface. Thus, we also investigated the influence of organic clays on reversible emulsions. It was demonstrated that a dosage of organic clay of ≤2.50 g/100 mL could maintain the reversible phase inversion performance of reversible emulsions. By analyzing the microstructure of the emulsion and the complex oil–water interface, we revealed the mechanism of the influence of organic clay on the reversible emulsion. Organic clay distributed at the oil–water interface not only formed a complex emulsifier with surfactants, but also affected the microstructure of the ...
Keywords	pH-responsive ; phase inversion ; microstructure ; bentonite clay ; Organic chemistry ; QD241-441
Subject code	550
Language	English
Publishing date	2023-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Simulating wood companies development considering the effect of ethical marketing

Zhenhuan Chen / Hongge Zhu / Fei Liu

Heliyon, Vol 9, Iss 1, Pp e13038- (2023)

2023

Abstract: Dedicating oneself to a greater good is one of the secret ingredients to business success in an evolving and highly interconnected markets environment. For wood companies, this is even more needed to face the overwhelming ongoing environmental crisis ... ...

Abstract	Dedicating oneself to a greater good is one of the secret ingredients to business success in an evolving and highly interconnected markets environment. For wood companies, this is even more needed to face the overwhelming ongoing environmental crisis affecting business practices and customers' behavior in general. To build solid reputation and increase one's presence on competing markets, wood companies should not only care about products competitiveness, but also customers' perception, environmental awareness and ethical marketing. In this article, we simulated the effect of ethical commerce on wood companies' reputation using a modified competitive and cooperative model based on differential equations considering wood type, products categories and companies brand score or reputation as function of their commitment to social and environmental causes. The qualitative analysis and results of numerical experiment show that, focusing on sharing values, and building strong relationship with customers are highly important for long-term development. Moreover, reducing environmental impact by shifting production strategy towards man-made materials could meet today customers' demands for ethically and environmentally aware manufactured wood products.
Keywords	Business success ; Wood companies ; Reputation management ; Consumer perception ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	650
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: “Reading A Book, By A Gain In Your Wit”--How to cultivate high school students' sustainable reading

Rui Wu / Fei Liu / Xiangfu Situ / Wei Huang

Heliyon, Vol 9, Iss 12, Pp e23333- (2023)

A multi-factor analysis

2023

Abstract: Reading cultivation is an important task of education. In order to ensure the sustainable reading behavior of high school students, more and more scholars begin to pay attention to the research of reading psychology. In order to explore the psychological ...

Abstract	Reading cultivation is an important task of education. In order to ensure the sustainable reading behavior of high school students, more and more scholars begin to pay attention to the research of reading psychology. In order to explore the psychological mechanism of high school students' reading, based on the theory of self-efficacy and achievement motivation, this study explores the chain intermediary model of 600 high school students' reading motivation influencing reading satisfaction through reading self-efficacy and social support. The results show that there are significant positive predictors among reading motivation, reading self-efficacy, social support and reading satisfaction. At the same time, reading self-efficacy and social support play an intermediary role between reading motivation and reading satisfaction of high school students respectively, and jointly play a chain intermediary role. The research results are of great theoretical and practical significance for understanding the reading psychology of senior high school students and ensuring their sustainable reading behavior.
Keywords	High school students ; Reading motivation ; Reading self-efficacy ; Social support ; Reading satisfaction ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Encapsulation of Tea Polyphenol in Zein through Complex Coacervation Technique to Control the Release of the Phenolic Compound from Gelatin–Zein Composite Film

Shabbir Ahammed / Md Easdani / Fei Liu / Fang Zhong

Polymers, Vol 15, Iss 2882, p

2023 Volume 2882

Abstract: Green tea polyphenol (TP) was encapsulated in zein and fabricated into a gelatin–zein composite film by complex coacervation. Transglutaminase (TG) crosslinking was employed to obtain a compact structural orientation of the film to prolong the release of ...

Abstract	Green tea polyphenol (TP) was encapsulated in zein and fabricated into a gelatin–zein composite film by complex coacervation. Transglutaminase (TG) crosslinking was employed to obtain a compact structural orientation of the film to prolong the release of bioactive compounds. The encapsulation efficiency of zein and the TP release rate from the composite film were investigated. The retention rate was over 30% and 80% after film fabrication and storage, respectively. Crosslinking decreased the diffusion coefficient by half, thus improving the release of TP from the film. The antioxidant properties were satisfactory after discharge from the film detected by DPPH/ABTS scavenging. The value of crosslinking degree (~60%) and increased molecular weight of the protein were investigated by SDS-PAGE, indicating the compatibility of TP and TG treatment. According to physicomechanical findings, the TG2TP1 film exhibited the best characteristics. Tensile strength and water solubility properties were ameliorated by the TG treatment of TP-encapsulated films compared to the control film. TG and TP-loaded gelatin–zein composite film had better thermal stability than the control film. Moreover, the TP loading reduced the transparency value and improved the light-barrier properties of the film. The films showed significant antimicrobial activities against two food-borne bacteria, including Staphylococcus aureus BCTC13962 and Escherichia coli BCRC10675. The result obtained shows that the encapsulation of TP and TG treatment may be used to fabricate gelatin–zein composite film with controlled release of phenolic compounds for active packaging applications.
Keywords	coacervation ; microencapsulation ; zein ; gelatin ; controlled release ; crosslinking ; Organic chemistry ; QD241-441
Subject code	660
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Study on the Properties Changes of Reversible Invert Emulsion during the Process from O/W to W/O with Alkali

Fei Liu / Yongfei Li / Xiaqing Li / Xuewu Wang

Molecules, Vol 29, Iss 1, p

2023 Volume 62

Abstract: The reversible emulsion drilling fluid system combines the advantages of both oil-based and water-based drilling fluids, which can achieve ideal results in different stages of drilling and completion, and the system can be reused to effectively reduce ... ...

Abstract	The reversible emulsion drilling fluid system combines the advantages of both oil-based and water-based drilling fluids, which can achieve ideal results in different stages of drilling and completion, and the system can be reused to effectively reduce costs. However, the research on reversible emulsions mainly focuses on the development of new reversible emulsifiers, while the specific phase transformation mechanism of reversible emulsion systems is still unclear. In this paper, a stable reversible emulsion was prepared using the reversible emulsifier DMOB as a raw material, and the reversible emulsion performance of the alkali response from the O/W emulsion phase to the W/O emulsion was studied. The microstructure of reversible emulsions was studied by a microscope, a cryogenic transmission electron microscopy, and a laser particle size analyzer. The changes in macroscopic properties of reversible emulsions in the process of alkali conversion were studied by pH, conductivity, demulsification voltage, static stability, viscosity, rheology, and other indicators, and the conversion mechanism of reversible emulsions from O/W emulsion ⟶ bicontinuous structure ⟶ O/W/O emulsion ⟶ W/O emulsion was clarified. The details are as follows: in the first stage, when the amount of NaOH ≤ 0.43 vol.%, the overall particle size of the emulsion decreases first and then increases with the increase in NaOH dosage. In the second stage, when the amount of NaOH was 0.45 vol.%, a double continuous structure was formed inside the emulsion. In the third stage, when the amount of NaOH is 0.48 vol.%, the O/W/O emulsion is formed, and with the increase in stirring time, the internal oil droplets gradually accumulate and are discharged from the water droplets, and finally, the W/O emulsion is formed. In the fourth stage, when the dosage of 0.50 vol.% ≤ NaOH ≤ 5.00 vol.%, the W/O emulsion was formed, and with the increase of NaOH dosage, the structure and compactness between water droplets increased first and then decreased. In the whole ...
Keywords	pH-responsive ; phase inversion ; microstructure ; reversible invert emulsion ; Organic chemistry ; QD241-441
Subject code	660
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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