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Article: Internet-based cognitive behavioral therapy intervention for youth with type 1 diabetes and depressive symptoms: a pilot and feasibility study.

Singh, Puja / Otero, Juan Mejia / Howe, Carol / Feinstein, Rebecca T / Gupta, Kushagra / Gladstone, Tracy R G / Van Voorhees, Benjamin W / Gupta, Olga T

mHealth

2023 Volume 10, Page(s) 6

Abstract: Depression is more common in youth with type 1 diabetes (T1D) compared to youth without diabetes. This study aims to assess the efficacy of Competent Adulthood Transition with Cognitive Humanistic and Interpersonal Teaching (CATCH-IT), an internet-based ... ...

Abstract	Depression is more common in youth with type 1 diabetes (T1D) compared to youth without diabetes. This study aims to assess the efficacy of Competent Adulthood Transition with Cognitive Humanistic and Interpersonal Teaching (CATCH-IT), an internet-based cognitive behavioral therapy (CBT) intervention, in adolescents with T1D and depressive symptoms. Adolescents (13 to 17 years old) with T1D and mild (score 5-9) or moderate (score 10-14) depressive symptoms on Patient Health Questionnaire-Adolescent (PHQ-A) screening assessment were recruited to participate and received online access to the CATCH-IT modules for 6 months (requested to complete in 12 weeks). Statistical analyses included paired
Language	English
Publishing date	2023-12-11
Publishing country	China
Document type	Journal Article
ISSN	2306-9740
ISSN	2306-9740
DOI	10.21037/mhealth-23-33
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Primary care-based screening and recruitment for an adolescent depression prevention trial: Contextual considerations during a youth mental health crisis.

Knepper, Amanda K / Feinstein, Rebecca T / Sanchez-Flack, Jennifer / Fitzgibbon, Marian / Lefaiver, Cheryl / McHugh, Ashley / Gladstone, Tracy R G / Van Voorhees, Benjamin W

Implementation research and practice

2024 Volume 5, Page(s) 26334895241246203

Abstract: Background: Rising rates of adolescent depression in the wake of COVID-19 and a youth mental health crisis highlight the urgent need for accessible mental healthcare and prevention within primary care. Digital mental health interventions (DMHIs) may ... ...

Abstract	Background: Rising rates of adolescent depression in the wake of COVID-19 and a youth mental health crisis highlight the urgent need for accessible mental healthcare and prevention within primary care. Digital mental health interventions (DMHIs) may increase access for underserved populations. However, these interventions are not well studied in adolescents, nor healthcare settings. The purpose of this study was to identify barriers and facilitators to screening and recruitment activities for Method: This qualitative study is a component of a larger Hybrid Type I trial. We conducted semi-structured key informant interviews with clinical and non-clinical implementers involved with screening and recruitment for the P2P trial. Informed by the Consolidated Framework for Implementation Research (CFIR), interviews were conducted at the midpoint of the trial to identify barriers, facilitators, and needed adaptations, and to gather information on determinants that may affect future implementation. Findings: Respondents perceived the P2P trial as valuable, well aligned with the mission of their health systems. However, several barriers were identified, many of which stemmed from influences outside of the healthcare settings. Universal and site-specific outer setting influences (COVID-19 pandemic, youth mental health crisis, local community conditions) interacted with Inner Setting and Innovation domains to create numerous challenges to the implementation of screening and recruitment. Conclusion: Our findings emphasize the need for ongoing, comprehensive assessment of dynamic inner and outer setting contexts prior to and during implementation of clinical trials, as well as flexibility for adaptation to unique clinical contexts. The CFIR is useful for assessing determinants during times of rapid inner and outer setting change, such as those brought on by the COVID-19 pandemic, youth mental health crisis, and the corresponding exacerbation of resource strain within healthcare settings. Clinical trial registration: PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents https://www.clinicaltrials.gov/study/NCT04290754.
Language	English
Publishing date	2024-04-22
Publishing country	United States
Document type	Journal Article
ISSN	2633-4895
ISSN (online)	2633-4895
DOI	10.1177/26334895241246203
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Article ; Online: PATHway: Intervention optimization of a prevention program for adolescents at-risk for depression in the primary care setting.

Gladstone, Tracy R G / Zhong, Cordelia / Lowther, Matthew / Feinstein, Rebecca T / Fitzgibbon, Marian L / Gussin, Hélène A / Schiffer, Linda / Diviak, Kathleen / Berbaum, Michael L / Rusiewski, Calvin / Ramirez, Paula / Lefaiver, Cheryl / Canel, Jason / Mitchell, James / Buchholz, Katherine R / Van Voorhees, Benjamin W

Contemporary clinical trials

2023 Volume 137, Page(s) 107413

Abstract: With as many as 13% of adolescents diagnosed with depressive disorders each year, prevention of depressive disorders has become a key priority for the National Institute of Mental Health (NIMH). Currently, we have no widely available interventions to ... ...

Abstract	With as many as 13% of adolescents diagnosed with depressive disorders each year, prevention of depressive disorders has become a key priority for the National Institute of Mental Health (NIMH). Currently, we have no widely available interventions to prevent these disorders. To address this need, we developed a multi-health system collaboration to develop and evaluate the primary care based technology "behavioral vaccine," Competent Adulthood Transition with Cognitive-Behavioral Humanistic and Interpersonal Therapy (CATCH-IT). The full CATCH-IT program demonstrated evidence of efficacy in prevention of depressive episodes in clinical trials. However, CATCH-IT became larger and more complex across trials, creating issues with adherence and scalability. We will use a multiphase optimization strategy approach to optimize CATCH-IT. The theoretically grounded components of CATCH-IT include: behavioral activation, cognitive-behavioral therapy, interpersonal psychotherapy, and parent program. We will use a 4-factor (2x2x2x2) fully crossed factorial design with N = 16 cells (25 per cell, after allowing 15% dropout) to evaluate the contribution of each component. Eligible at-risk youth will be high school students 13 through 18 years old, with subsyndromal symptoms of depression. The study design will enable us to eliminate non-contributing components while preserving efficacy and to optimize CATCH-IT by strengthening tolerability and scalability by reducing resource use. By reducing resource use, we anticipate satisfaction and acceptability will also increase, preparing the way for an implementation trial.
MeSH term(s)	Adolescent ; Humans ; Cognitive Behavioral Therapy ; Depression/prevention & control ; Primary Health Care ; Research Design ; Students
Language	English
Publishing date	2023-12-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2182176-8
ISSN	1559-2030 ; 1551-7144
ISSN (online)	1559-2030
ISSN	1551-7144
DOI	10.1016/j.cct.2023.107413
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Article ; Online: Adverse Childhood Experiences Are Associated with Unmet Healthcare Needs among Children with Autism Spectrum Disorder.

Berg, Kristin L / Shiu, Cheng-Shi / Feinstein, Rebecca T / Msall, Michael E / Acharya, Kruti

The Journal of pediatrics

2018 Volume 202, Page(s) 258–264.e1

Abstract: Objective: To explore associations between level of adverse childhood experiences (ACEs) and unmet healthcare needs among children with autism spectrum disorder (ASD) using a population-based sample.: Study design: Cross-sectional data from the 2011- ... ...

Abstract	Objective: To explore associations between level of adverse childhood experiences (ACEs) and unmet healthcare needs among children with autism spectrum disorder (ASD) using a population-based sample. Study design: Cross-sectional data from the 2011-2012 National Survey of Child Health were analyzed to estimate prevalence of unmet healthcare needs among children with ASD, aged 2-17 years (ASD = 1624; estimated population = 1 174 871). Multivariate Poisson and logistic regression models were used to estimate the relationship between reported ACEs and unmet healthcare needs among children with ASD. Results: After we adjusted for all other variables, children with ASD who experienced 1-2 ACEs and 3+ ACEs were associated with 1.78 (P < .05) and 2.53 (P < .01) times the incidence rate of unmet healthcare needs in comparison with children without ACEs. Compared with children who experienced 0 ACEs, the adjusted odds of any unmet healthcare need were 2.34 (P < .01) and 2.66 (P < .01) for children with 1-2 ACEs and 3 + ACEs, respectively. Conclusion: Although limited to cross-sectional data, our study provides compelling evidence on the link between ACEs and unmet healthcare needs among children with ASD. It advances understanding of risk factors in the child and community context that contribute to health disparities and negatively impact healthcare access and use in this population.
MeSH term(s)	Adolescent ; Adverse Childhood Experiences/statistics & numerical data ; Autism Spectrum Disorder/diagnosis ; Autism Spectrum Disorder/epidemiology ; Autism Spectrum Disorder/therapy ; Child ; Child Health Services/organization & administration ; Child, Preschool ; Cross-Sectional Studies ; Disabled Children/rehabilitation ; Disabled Children/statistics & numerical data ; Female ; Health Services Accessibility/statistics & numerical data ; Health Services Needs and Demand ; Humans ; Logistic Models ; Male ; Outcome Assessment (Health Care) ; Retrospective Studies ; Risk Assessment ; Socioeconomic Factors ; United States
Language	English
Publishing date	2018-09-14
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3102-1
ISSN	1097-6833 ; 0022-3476
ISSN (online)	1097-6833
ISSN	0022-3476
DOI	10.1016/j.jpeds.2018.07.021
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Article ; Online: PATH 2 Purpose: Design of a comparative effectiveness study of prevention programs for adolescents at-risk for depression in the primary care setting.

Gladstone, Tracy R G / Feinstein, Rebecca T / Fitzgibbon, Marian L / Schiffer, Linda / Berbaum, Michael L / Lefaiver, Cheryl / Pössel, Patrick / Diviak, Kathleen / Wang, Tianxiu / Knepper, Amanda K / Sanchez-Flack, Jennifer / Rusiewski, Calvin / Potts, Diane / Buchholz, Katherine R / Myers, Taylor L / Van Voorhees, Benjamin W

Contemporary clinical trials

2022 Volume 117, Page(s) 106763

Abstract: The majority of mental, emotional, and behavioral (MEB) disorders have an initial onset before age 24, with 20% annual incidence, and with major depressive disorder (MDD) being the most common MEB. Health systems may be able to reduce costs by ... ...

Abstract	The majority of mental, emotional, and behavioral (MEB) disorders have an initial onset before age 24, with 20% annual incidence, and with major depressive disorder (MDD) being the most common MEB. Health systems may be able to reduce costs by transitioning from the current treatment-focused model for MDD to a prevention model. However, evidence is needed for (1) the comparative effectiveness of a "scalable intervention" and (2) an implementation model for such a scalable intervention in the primary care setting. This paper describes a comparative effectiveness trial evaluating the efficacy of two evidence-based cognitive-behavioral prevention (CBP) programs: Teens Achieving Mastery over Stress (TEAMS), the "gold standard," group therapy model, and Competent Adulthood Transition with Cognitive Behavioral, Humanistic and Interpersonal Training (CATCH-IT), a scalable, self-directed, technology-based model. Eligible adolescents, age 13-19, are offered one of these two depression prevention programs across five health systems (30 clinics) in urban and suburban Chicago, IL, rural Western IL, and Louisville, KY. We are comprehensively evaluating patient-centered outcomes and stakeholder-valued moderators of effect versus baseline at two, six, 12, and 18-month assessment points. Using a hybrid clinical trial design that simultaneously examines the implementation process, the study is also assessing adolescents', parents', and providers' experiences (e.g., efficacy, time commitment, cultural acceptability) within each intervention approach.
MeSH term(s)	Adolescent ; Adult ; Cognitive Behavioral Therapy ; Depression/prevention & control ; Depressive Disorder, Major/prevention & control ; Humans ; Primary Health Care ; Psychotherapy, Group ; Young Adult
Language	English
Publishing date	2022-04-15
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2182176-8
ISSN	1559-2030 ; 1551-7144
ISSN (online)	1559-2030
ISSN	1551-7144
DOI	10.1016/j.cct.2022.106763
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1581: Show issues

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Article ; Online: Children with developmental disabilities experience higher levels of adversity.

Berg, Kristin L / Shiu, Cheng-Shi / Feinstein, Rebecca T / Acharya, Kruti / MeDrano, Jonathan / Msall, Michael E

Research in developmental disabilities

2019 Volume 89, Page(s) 105–113

Abstract: Objective: Individuals with developmental disabilities (DD) experience significant health disparities. An overlooked risk factor for health disparities in the DD population is adverse childhood experiences (ACEs). The purpose of this study was to ... ...

Abstract	Objective: Individuals with developmental disabilities (DD) experience significant health disparities. An overlooked risk factor for health disparities in the DD population is adverse childhood experiences (ACEs). The purpose of this study was to generate population prevalence data about level of adverse experiences among children with DD in comparison to children without DD and the extent to which potential confounders may influence observed associations between adversity and child DD status. Methods: Data from the 2011-12 National Survey of Child Health (NSCH) were analyzed to estimate prevalence of adversity among families of children with and without DD, age 3-17 years (N = 62,428; DD = 2622). Level of adversity was assessed via parent response to the Adverse Family Experiences questionnaire. Bivariate and multinomial logistic regressions were utilized to investigate the relationship between adverse family experiences (AFEs) and child DD status, adjusting for covariates. Results: Child DD status was significantly and independently associated with higher probability of reporting 1-2 AFEs (RRR = 1.28, 95% CI 1.06, 1.5) and 3+ AFEs (RRR = 1.60, 95% CI 1.16, 2.21). Conclusion: This study documents significant disparities in adversity among children with DD using a population-based sample. These adversities potentially compromise successful transition to adulthood and overall health outcomes.
MeSH term(s)	Adolescent ; Adverse Childhood Experiences/statistics & numerical data ; Child ; Child, Preschool ; Developmental Disabilities/epidemiology ; Developmental Disabilities/psychology ; Family Characteristics ; Family Relations/psychology ; Female ; Humans ; Male ; Prevalence ; Risk Factors ; Social Determinants of Health/statistics & numerical data ; Socioeconomic Factors ; United States/epidemiology
Language	English
Publishing date	2019-04-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	639175-8
ISSN	1873-3379 ; 0891-4222
ISSN (online)	1873-3379
ISSN	0891-4222
DOI	10.1016/j.ridd.2019.03.011
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Article ; Online: BEhavioral Health Stratified Treatment (B.E.S.T.) to optimize transition to adulthood for youth with intellectual and/or developmental disabilities.

Berg, Kristin L / Mihaila, Iulia / Feinstein, Rebecca T / Shiu, Cheng-Shi / Gussin, Helene / Acharya, Kruti / Gladstone, Tracy R G / Bernard, Leah / Best, Megan / Renz, Ellie / Abdallah, Ghada / Weldy, Sarah / Herrman, Deana / Lynch, Emma / Gerges, Michael / Perez, Patricia / Buchholz, Katherine R / Msall, Michael / Aaron, Suzanne /

Mutti, Megan / Arnold, Catherine / Danguilan, Chris / Argueta, Isai / Hunter, Madeline / Pela, Emily / Diviak, Kathleen / Kuhn, Jocelyn / Berbaum, Michael L / Van Voorhees, Benjamin W

Contemporary clinical trials

2023 Volume 136, Page(s) 107374

Abstract: Youth with intellectual and/or developmental disabilities (IDD) often struggle with depression and anxiety, which adversely impacts transition to adulthood. Integrated behavioral health care coordination, wherein care coordinators and behavioral health ... ...

Abstract	Youth with intellectual and/or developmental disabilities (IDD) often struggle with depression and anxiety, which adversely impacts transition to adulthood. Integrated behavioral health care coordination, wherein care coordinators and behavioral health specialists collaborate to provide systematic, cost-effective, patient-centered care, is a promising strategy to improve access to behavioral health services and address factors that impact transition to adulthood, including depression/anxiety symptoms. Current care coordination models (e.g., Title V Maternal and Child Health Bureau [MCHB]) do not include behavioral health services. The CHECK (Coordinated HealthCarE for Complex Kids) mental health model, hereby refined and renamed BEhavioral Health Stratified Treatment (B.E.S.T.), is a behavioral health intervention delivery program designed for integration into care coordination programs. This study aims to determine whether an integrated behavioral health care coordination strategy (i.e., MCHB care coordination plus B.E.S.T.) would be more acceptable and lead to better youth health and transition outcomes, relative to standard care coordination (i.e., MCHB care coordination alone). Results would guide future investment in improving outcomes for youth with IDD. This study is a two-arm randomized clinical trial of 780 transition-aged youth with IDD (13-20 years) to evaluate the comparable efficacy of MCHB Care Coordination alone vs. MCHB Care Coordination plus B.E.S.T. on the following outcomes: 1) decreased symptoms and episodes of depression and anxiety over time; 2) improved health behaviors, adaptive functioning and health related quality of life; 3) increased health care transition (HCT) readiness; and 4) improved engagement and satisfaction with care coordination among stakeholders.
MeSH term(s)	Adolescent ; Humans ; Anxiety Disorders/therapy ; Delivery of Health Care ; Developmental Disabilities ; Intellectual Disability ; Quality of Life ; Transition to Adult Care ; Young Adult
Language	English
Publishing date	2023-10-28
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2182176-8
ISSN	1559-2030 ; 1551-7144
ISSN (online)	1559-2030
ISSN	1551-7144
DOI	10.1016/j.cct.2023.107374
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Zs.A 1581: Show issues

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Article: Internet-based cognitive behavioral therapy intervention for youth with type 1 diabetes and depressive symptoms: a pilot and feasibility study.

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Inter-library loan at ZB MED

Article ; Online: Primary care-based screening and recruitment for an adolescent depression prevention trial: Contextual considerations during a youth mental health crisis.

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Article ; Online: PATHway: Intervention optimization of a prevention program for adolescents at-risk for depression in the primary care setting.

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Article ; Online: Adverse Childhood Experiences Are Associated with Unmet Healthcare Needs among Children with Autism Spectrum Disorder.

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Article ; Online: PATH 2 Purpose: Design of a comparative effectiveness study of prevention programs for adolescents at-risk for depression in the primary care setting.

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Article ; Online: Children with developmental disabilities experience higher levels of adversity.

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Article ; Online: BEhavioral Health Stratified Treatment (B.E.S.T.) to optimize transition to adulthood for youth with intellectual and/or developmental disabilities.

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