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  1. Book: Blood feuds

    Feldman, Eric A.

    AIDS, blood, and the politics of medical disaster

    1999  

    Author's details ed. by Eric A. Feldman
    Language English
    Size XIII, 375 S.
    Publisher Oxford Univ. Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT010915984
    ISBN 0-19-512929-6 ; 0-19-513160-6 ; 978-0-19-512929-8 ; 978-0-19-513160-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1999 A 5180 order for loan Magazin

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  2. Article: Baby M Turns 30: The Law and Policy of Surrogate Motherhood.

    Feldman, Eric A

    American journal of law & medicine

    2018  Volume 44, Issue 1, Page(s) 7–22

    Abstract: This article marks the ... ...

    Abstract This article marks the 30
    MeSH term(s) Birth Certificates/legislation & jurisprudence ; Contracts/legislation & jurisprudence ; Female ; Humans ; Mothers/legislation & jurisprudence ; Pregnancy ; Reproductive Techniques, Assisted/legislation & jurisprudence ; Surrogate Mothers/legislation & jurisprudence ; United States ; Women's Rights/legislation & jurisprudence
    Language English
    Publishing date 2018-05-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 753043-2
    ISSN 0098-8588
    ISSN 0098-8588
    DOI 10.1177/0098858818763811
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1334: Show issues Location:
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  3. Article ; Online: Novel Therapeutics for Therapy-Related Acute Myeloid Leukemia: 2014.

    Feldman, Eric J

    Clinical lymphoma, myeloma & leukemia

    2015  Volume 15 Suppl, Page(s) S91–3

    Abstract: Effective treatment options for adults with therapy-related AML continues to be an area of unmet need. Genetic and molecular changes within these leukemias confer resistance to standard chemotherapy regimens. Emerging developmental therapeutics in this ... ...

    Abstract Effective treatment options for adults with therapy-related AML continues to be an area of unmet need. Genetic and molecular changes within these leukemias confer resistance to standard chemotherapy regimens. Emerging developmental therapeutics in this area has focused on several approaches. These include; novel delivery of chemotherapy as well as newer DNA-damaging agents delivered through antibody-drug conjugates, increased use of hypomethylating agents, and molecularly-directed small molecules against specific mutations commonly occurring in secondary AML. Results of this efforts are encouraging, but to date, no clear improvements have been demonstrated in this most difficult to treat population.
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/etiology ; Treatment Outcome
    Language English
    Publishing date 2015-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2540992-X
    ISSN 2152-2669 ; 2152-2650
    ISSN (online) 2152-2669
    ISSN 2152-2650
    DOI 10.1016/j.clml.2015.02.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Curbside Consults in Clinical Medicine: Empirical and Liability Challenges.

    Zacharias, Rachel L / Feldman, Eric A / Joffe, Steven / Lynch, Holly Fernandez

    The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics

    2022  Volume 49, Issue 4, Page(s) 599–610

    Abstract: In most U.S. jurisdictions, clinicians providing informal "curbside" consults are protected from medical malpractice liability due to the absence of a doctor-patient relationship. A recent Minnesota Supreme Court case, Warren v. Dinter, offers the ... ...

    Abstract In most U.S. jurisdictions, clinicians providing informal "curbside" consults are protected from medical malpractice liability due to the absence of a doctor-patient relationship. A recent Minnesota Supreme Court case, Warren v. Dinter, offers the opportunity to reassess whether the majority rule is truly serving the best interests of patients.
    MeSH term(s) Clinical Medicine ; Humans ; Liability, Legal ; Malpractice ; Physician-Patient Relations ; Referral and Consultation
    Language English
    Publishing date 2022-01-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 1168812-9
    ISSN 1748-720X ; 1073-1105 ; 0277-8459
    ISSN (online) 1748-720X
    ISSN 1073-1105 ; 0277-8459
    DOI 10.1017/jme.2021.83
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    Zs.A 2075: Show issues Location:
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  5. Article: Shots for tots?

    Feldman, Eric A

    The Hastings Center report

    2013  Volume 43, Issue 3, Page(s) 34–35

    MeSH term(s) Bioethics ; Humans ; Smoking/immunology ; Smoking Cessation/methods ; Smoking Prevention ; Vaccines/immunology
    Chemical Substances Vaccines
    Language English
    Publishing date 2013-05
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 194940-8
    ISSN 1552-146X ; 0093-0334
    ISSN (online) 1552-146X
    ISSN 0093-0334
    DOI 10.1002/hast.175
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  6. Article ; Online: The Genetic Information Nondiscrimination Act (GINA): public policy and medical practice in the age of personalized medicine.

    Feldman, Eric A

    Journal of general internal medicine

    2012  Volume 27, Issue 6, Page(s) 743–746

    Abstract: Survey data suggest that many people fear genetic discrimination by health insurers or employers. In fact, such discrimination has not yet been a significant problem. This article examines the fear and reality of genetic discrimination in the United ... ...

    Abstract Survey data suggest that many people fear genetic discrimination by health insurers or employers. In fact, such discrimination has not yet been a significant problem. This article examines the fear and reality of genetic discrimination in the United States, describes how Congress sought to prohibit such discrimination by passing the Genetic Information Nondiscrimination Act of 2008 (GINA), and explores the implications of GINA for general internists and their institutions. It concludes that medical providers and health care institutions must be familiar with the general intent and specific terms of GINA, and should continue to collect genetic information that can contribute to the high quality provision of medical treatment. Not doing so violates their medical mission and diminishes the quality of care patients deserve.
    MeSH term(s) Genetic Privacy/legislation & jurisprudence ; Genetic Testing/legislation & jurisprudence ; Humans ; Legislation, Medical ; Precision Medicine/methods ; Prejudice ; Public Policy ; United States
    Language English
    Publishing date 2012-02-08
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-012-1988-6
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    Zs.A 2205: Show issues Location:
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  7. Article ; Online: Improving Unrelated Donor Equity: Assessing Mismatched Donor Opportunities with Real-World Data in a Minority-Predominant Cohort.

    Hammami, M Bakri / Verceles, Jhannine Alyssa / Goldfinger, Mendel / Shah, Nishi / Sica, R Alejandro / Mantzaris, Ioannis / Kornblum, Noah / Konopleva, Marina / Shastri, Aditi / Shapiro, Lauren C / Feldman, Eric J / Gritsman, Kira / Verma, Amit / Cooper, Dennis L

    Transplantation and cellular therapy

    2024  

    Abstract: Recent advances in graft-versus-host disease (GVHD) prophylaxis including post-transplant cyclophosphamide (PTCy) and abatacept have significantly improved outcomes following HLA-mismatched allogenic hematopoietic stem cell transplantation (allo-HSCT) ... ...

    Abstract Recent advances in graft-versus-host disease (GVHD) prophylaxis including post-transplant cyclophosphamide (PTCy) and abatacept have significantly improved outcomes following HLA-mismatched allogenic hematopoietic stem cell transplantation (allo-HSCT) and have tremendous potential for reducing racial disparities in donor availability. A recent small study employing bone marrow as the source of stem cells showed similar outcomes after 5/8 versus 7/8 matches and is currently being tested in a larger study using peripheral blood stem cells. In this study, we examine real-world alternative donor HSCT options for a minority-predominant cohort in the Bronx, NY, focusing on the availability of lesser-matched (5/8 to 7/8) donors. Records of patients who underwent HLA typing at Montefiore Medical Center (2019 to 2022) were reviewed. The National Marrow Donor Program registry was queried to evaluate the availability of donors with at least 99% likelihood of HLA match at various levels (5/8, 6/8, 7/8, 8/8). Two hundred forty-one patients were included, 70% were non-White. Although the availability of ≥7/8 donors was less common in non-White patients, 100% of patients from each group had at least one or more 5/8 and 6/8 HLA-matched donors and more than 80% of these patients had >100 potential 5/8 and 6/8 HLA-matched donors. There was no statistical difference by race or ethnicity in the mean number of donors at 5/8 and 6/8 HLA-match levels. We demonstrate through real-world data that patients from diverse ethnic and racial backgrounds have access to 5/8 and 6/8 HLA-matched donors for allo-HSCT, potentially eliminating disparities in donor availability and allowing prioritization of other donor selection characteristics such as donor age, sex, ABO, and B leader matching. Further work is needed to study whether the use of mismatched donors offers a more potent graft-versus malignancy effect and optimal GVHD prophylaxis.
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3062231-1
    ISSN 2666-6367
    ISSN (online) 2666-6367
    DOI 10.1016/j.jtct.2024.02.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5082: Show issues Location:
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  8. Article ; Online: Too much ara-C? Not enough daunorubicin?

    Feldman, Eric J

    Blood

    2011  Volume 117, Issue 8, Page(s) 2299–2300

    Abstract: It seems strange, but after 40 years of experience using cytosine arabinoside (ara-C) and daunorubicin, leukemia doctors are still unsure as to how much of each drug they should use to treat their patients with acute myeloid leukemia (AML). ...

    Abstract It seems strange, but after 40 years of experience using cytosine arabinoside (ara-C) and daunorubicin, leukemia doctors are still unsure as to how much of each drug they should use to treat their patients with acute myeloid leukemia (AML).
    Language English
    Publishing date 2011-02-23
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood-2011-01-328633
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Does therapy-related AML have a poor prognosis, independent of the cytogenetic/molecular determinants?

    Feldman, Eric J

    Best practice & research. Clinical haematology

    2011  Volume 24, Issue 4, Page(s) 523–526

    Abstract: Do patients with therapy-related acute myeloid leukemia (t-AML) have a poor prognosis independent of other predictive variables such as cytogenetics or molecular determinants? Limited data exist to answer this question in part because t-AML is often ... ...

    Abstract Do patients with therapy-related acute myeloid leukemia (t-AML) have a poor prognosis independent of other predictive variables such as cytogenetics or molecular determinants? Limited data exist to answer this question in part because t-AML is often considered together with AML following myelodysplastic syndromes (MDS) in the category of secondary AML. This discussion provides some insight, based primarily on two published retrospective reviews of the German cooperative groups, into the question of whether t-AML is an independent adverse variable.
    MeSH term(s) Anthracyclines/administration & dosage ; Anthracyclines/adverse effects ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Biomarkers, Tumor/genetics ; Cytarabine/administration & dosage ; Cytarabine/adverse effects ; Cytogenetics ; Female ; Germany ; Humans ; Leukemia, Myeloid, Acute/chemically induced ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/etiology ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/mortality ; Middle Aged ; Myelodysplastic Syndromes/complications ; Myelodysplastic Syndromes/diagnosis ; Myelodysplastic Syndromes/drug therapy ; Myelodysplastic Syndromes/genetics ; Myelodysplastic Syndromes/mortality ; Naphthalimides/administration & dosage ; Naphthalimides/therapeutic use ; Naphthyridines/administration & dosage ; Naphthyridines/therapeutic use ; Prognosis ; Remission Induction ; Retrospective Studies ; Survival Rate ; Thiazoles/administration & dosage ; Thiazoles/therapeutic use
    Chemical Substances Anthracyclines ; Antineoplastic Agents ; Biomarkers, Tumor ; Naphthalimides ; Naphthyridines ; Thiazoles ; Cytarabine (04079A1RDZ) ; amonafide (1Q8D39N37L) ; vosaroxin (K6A90IIZ19)
    Language English
    Publishing date 2011-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2048027-1
    ISSN 1532-1924 ; 1521-6926
    ISSN (online) 1532-1924
    ISSN 1521-6926
    DOI 10.1016/j.beha.2011.09.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Antibody-Based Treatment of Acute Myeloid Leukemia.

    Garfin, Phillip M / Feldman, Eric J

    Current hematologic malignancy reports

    2016  Volume 11, Issue 6, Page(s) 545–552

    Abstract: While antibody-based therapies have emerged as clinically effective approaches for several hematologic and solid malignancies, they have not played a significant role to date in the treatment of acute myeloid leukemia (AML). More recently, improvements ... ...

    Abstract While antibody-based therapies have emerged as clinically effective approaches for several hematologic and solid malignancies, they have not played a significant role to date in the treatment of acute myeloid leukemia (AML). More recently, improvements in antibody-drug conjugate technology, bispecific antibodies, as well as identification of novel AML antigens have re-invigorated enthusiasm for antibody-based therapies for AML. This review describes experiences with former and existing antibody-based therapies for AML, including unconjugated antibodies, antibody-drug conjugates (ADCs), radio-labelled antibodies, and immune-engaging antibodies, and discusses the promise and challenges associated with each.
    MeSH term(s) Aminoglycosides/therapeutic use ; Antibodies, Monoclonal/immunology ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal, Humanized/therapeutic use ; Humans ; Immunoconjugates/therapeutic use ; Interleukin-3 Receptor alpha Subunit/immunology ; Leukemia, Myeloid, Acute/drug therapy ; Radioimmunotherapy ; Sialic Acid Binding Ig-like Lectin 3/immunology
    Chemical Substances Aminoglycosides ; Antibodies, Monoclonal ; Antibodies, Monoclonal, Humanized ; Immunoconjugates ; Interleukin-3 Receptor alpha Subunit ; Sialic Acid Binding Ig-like Lectin 3 ; gemtuzumab (93NS566KF7) ; SGN-30 monoclonal antibody (C67ORA155P)
    Language English
    Publishing date 2016-10-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2229765-0
    ISSN 1558-822X ; 1558-8211
    ISSN (online) 1558-822X
    ISSN 1558-8211
    DOI 10.1007/s11899-016-0349-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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