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  1. Article ; Online: Venipuncture Site Influences Blood-drop Volume in C57BL/6 Mice.

    Lavin, Elizabeth S / Feldman, Erica R / Soprano, Scott M / Moore, Elizabeth S

    Journal of the American Association for Laboratory Animal Science : JAALAS

    2024  

    Abstract: Many experiments require the collection of serial blood samples from mice. However, the size of mice limits the volume of blood that can be safely collected as a survival procedure. In IACUC protocols, investigators may report the amount of blood they ... ...

    Abstract Many experiments require the collection of serial blood samples from mice. However, the size of mice limits the volume of blood that can be safely collected as a survival procedure. In IACUC protocols, investigators may report the amount of blood they collect from mice as a number of drops. Many institutions, including ours, use an anecdotal conversion factor (1 drop of mouse blood = 25 µL) to ensure that blood-collection volumes are compliant with institutional guidelines. To our knowledge, previous work has not experimentally determined the volume of a drop of mouse blood. In this 10-wk crossover experiment, 2 phlebotomists bled 30 C57BL/6J mice from 3 sites (facial, saphenous, and tail) using one or 2 different needle gauge sizes per site. Male and female mice were weighed weekly and divided among 5 groups (
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Journal Article
    ISSN 2769-6677
    ISSN (online) 2769-6677
    DOI 10.30802/AALAS-JAALAS-23-000083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Spontaneous Pituitary Neoplasm in Two Female Geriatric Southern Giant Pouched Rats (

    Voigt, Anna L / Nelissen, Sophie / Percival, Aaron J / Voss, Henning U / Lavin, Elizabeth S / Miller, Andrew D / Feldman, Erica R

    Comparative medicine

    2024  Volume 73, Issue 6, Page(s) 486–493

    Abstract: Southern giant pouched rats ( ...

    Abstract Southern giant pouched rats (
    MeSH term(s) Animals ; Female ; Rats ; Pituitary Neoplasms/diagnostic imaging ; Pituitary Neoplasms/veterinary ; Rodent Diseases/diagnosis
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2006425-1
    ISSN 2769-819X ; 0023-6764 ; 1532-0820
    ISSN (online) 2769-819X
    ISSN 0023-6764 ; 1532-0820
    DOI 10.30802/AALAS-CM-23-000051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Comparison of Effects of Capromorelin and Mirtazapine on Appetite in New Zealand White Rabbits (

    Draper, Janna Mh / Savson, Daniel J / Lavin, Elizabeth S / Feldman, Erica R / Singh, Bhupinder / Martin-Flores, Manuel / Daugherity, Erin K

    Journal of the American Association for Laboratory Animal Science : JAALAS

    2022  Volume 61, Issue 5, Page(s) 495–505

    Abstract: Inappetence is a welfare concern in rabbits ( ...

    Abstract Inappetence is a welfare concern in rabbits (
    MeSH term(s) Animals ; Rabbits ; Appetite ; Appetite Stimulants/pharmacology ; Mirtazapine/pharmacology ; Piperidines ; Pyrazoles
    Chemical Substances Appetite Stimulants ; CP 424391 ; Mirtazapine (A051Q2099Q) ; Piperidines ; Pyrazoles
    Language English
    Publishing date 2022-08-18
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial, Veterinary ; Research Support, Non-U.S. Gov't
    ISSN 2769-6677
    ISSN (online) 2769-6677
    DOI 10.30802/AALAS-JAALAS-22-000003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Effects of Cisapride, Buprenorphine, and Their Combination on Gastrointestinal Transit in New Zealand White Rabbits.

    Feldman, Erica R / Singh, Bhupinder / Mishkin, Noah G / Lachenauer, Erica R / Martin-Flores, Manuel / Daugherity, Erin K

    Journal of the American Association for Laboratory Animal Science : JAALAS

    2021  Volume 60, Issue 2, Page(s) 221–228

    Abstract: Due to their effective analgesic properties, opioids are worthy of consideration for pain management in rabbits. However, this class of drugs causes undesirable effects including reduced gastrointestinal (GI) motility, reduced fecal output, and delays GI ...

    Abstract Due to their effective analgesic properties, opioids are worthy of consideration for pain management in rabbits. However, this class of drugs causes undesirable effects including reduced gastrointestinal (GI) motility, reduced fecal output, and delays GI transit times and thus increases the risk of GI stasis. The risk of stasis discourages the use of opioids in rabbits, which could affect animal welfare. Gastroprokinetic agents such as cisapride are effective in promoting gastric emptying in many species, but whether this effect occurs in rabbits is unknown. This study assessed the efficacy of cisapride when administered as a single agent and in combination with buprenorphine in rabbits; efficacy was assessed by measuring GI transit times, fecal output, body weight, and food and water intake. Female New Zealand White rabbits (
    MeSH term(s) Analgesics, Opioid/administration & dosage ; Analgesics, Opioid/pharmacology ; Animals ; Buprenorphine/administration & dosage ; Buprenorphine/pharmacology ; Cisapride/administration & dosage ; Cisapride/pharmacology ; Cross-Over Studies ; Female ; Gastric Emptying/drug effects ; Gastrointestinal Agents/pharmacology ; Gastrointestinal Motility/drug effects ; Gastrointestinal Transit/drug effects ; Rabbits/physiology ; Random Allocation
    Chemical Substances Analgesics, Opioid ; Gastrointestinal Agents ; Buprenorphine (40D3SCR4GZ) ; Cisapride (UVL329170W)
    Language English
    Publishing date 2021-02-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1559-6109
    ISSN 1559-6109
    DOI 10.30802/AALAS-JAALAS-20-000064
    Database MEDical Literature Analysis and Retrieval System OnLINE

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