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  1. Article ; Online: Opportunities for patient-centered sleep research.

    Feldman, Harold I

    Sleep

    2023  Volume 46, Issue 9

    MeSH term(s) Humans ; Sleep ; Patients ; Patient-Centered Care
    Language English
    Publishing date 2023-06-22
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 424441-2
    ISSN 1550-9109 ; 0161-8105
    ISSN (online) 1550-9109
    ISSN 0161-8105
    DOI 10.1093/sleep/zsad125
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  2. Article ; Online: The discipline of epidemiology: engaging in the full breadth of population health science.

    Feldman, Harold I

    Annals of epidemiology

    2018  Volume 28, Issue 6, Page(s) 347–349

    Abstract: This address was delivered by Harold I. Feldman, MD, MSCE, at the Annual Meeting of the American College of Epidemiology in New Orleans, Louisiana, on September 26, 2017. Dr. Feldman is George S. Pepper Professor of Public Health and Preventive Medicine, ...

    Abstract This address was delivered by Harold I. Feldman, MD, MSCE, at the Annual Meeting of the American College of Epidemiology in New Orleans, Louisiana, on September 26, 2017. Dr. Feldman is George S. Pepper Professor of Public Health and Preventive Medicine, Professor of Epidemiology and Medicine, and Chair, Department of Biostatistics, Epidemiology, and Informatics at the Perelman School of Medicine at the University of Pennsylvania. He is recognized nationally and internationally for his expertise in kidney disease epidemiology. Dr. Feldman pioneered the integration of epidemiology and renal medicine with his first studies of dialyzer reuse and hemodialysis vascular access morbidity. He is internationally renowned in nephrology and clinical epidemiology and an architect of one of the largest and most successful epidemiological research programs in chronic kidney disease. For over 15 years, he has led NIH's Chronic Renal Insufficiency Cohort Study, placing him at the helm of the "Framingham Study of Renal Disease". It has elucidated the chronic kidney disease-specific relationships of mineral dysmetabolism and cardiovascular complications; dietary sodium and heart failure; novel vascular stiffness metrics and renal disease progression; cardiovascular biomarkers and heart failure; and cognitive decline and renal dysfunction, among others. He has also led the nation's largest trials targeting hemodialysis vascular access morbidity, discovered the benefits of transplantation before dialysis dependence, elucidated racial disparities and the role of genetics in kidney failure, and shaped our understanding of the toxicity from unregulated reuse of medical devices. He is the past President of the American College of Epidemiology and directs one of the nation's largest clinical epidemiology and biostatistics programs. Dr. Feldman has an MD from Boston University and an MSCE from the University of Pennsylvania. He is an elected member of the American Society of Clinical Investigation, the Association of American Physicians, and the American Epidemiological Society.
    MeSH term(s) Congresses as Topic ; Epidemiology ; Humans ; Population Health ; Public Health ; Translational Medical Research
    Language English
    Publishing date 2018-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1074355-8
    ISSN 1873-2585 ; 1047-2797
    ISSN (online) 1873-2585
    ISSN 1047-2797
    DOI 10.1016/j.annepidem.2018.03.009
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  3. Article ; Online: Race and the Estimation of GFR: Getting It Right.

    Feldman, Harold I / Briggs, Josephine P

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2021  Volume 78, Issue 1, Page(s) 3–4

    MeSH term(s) Creatinine ; Glomerular Filtration Rate ; Humans
    Chemical Substances Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2021-04-09
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2021.03.009
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  4. Article ; Online: Race and the Estimation of GFR: Getting it Right.

    Feldman, Harold I / Briggs, Josephine P

    Journal of the American Society of Nephrology : JASN

    2021  Volume 32, Issue 6, Page(s) 1269–1270

    MeSH term(s) Creatinine ; Glomerular Filtration Rate
    Chemical Substances Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2021-04-09
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2021020206
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    Zs.A 3344: Show issues Location:
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  5. Article ; Online: AJKD on the Move.

    Feldman, Harold I

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2016  Volume 69, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; Nephrology/education ; Nephrology/methods ; Publishing/standards ; Quality Improvement ; United States
    Language English
    Publishing date 2016-12-22
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2016.10.003
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  6. Article ; Online: Celebrating 4 Decades of AJKD.

    Feldman, Harold I / Berns, Jeffrey S / Dember, Laura M / Dorman, Nijsje M

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2021  Volume 78, Issue 1, Page(s) 1–2

    MeSH term(s) History, 20th Century ; History, 21st Century ; Nephrology ; Periodicals as Topic/history ; United States
    Language English
    Publishing date 2021-06-25
    Publishing country United States
    Document type Editorial ; Historical Article
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2021.05.001
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  7. Article ; Online: Introduction: A Foreword to CKD.

    Feldman, Harold I / Anderson, Amanda Hyre

    Seminars in nephrology

    2016  Volume 36, Issue 4, Page(s) 251

    Language English
    Publishing date 2016-07
    Publishing country United States
    Document type Editorial
    ZDB-ID 604652-6
    ISSN 1558-4488 ; 0270-9295
    ISSN (online) 1558-4488
    ISSN 0270-9295
    DOI 10.1016/j.semnephrol.2016.05.001
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  8. Article ; Online: Analysis of Estimated and Measured Glomerular Filtration Rates and the CKD-EPI Equation Race Coefficient in the Chronic Renal Insufficiency Cohort Study.

    Hsu, Chi-Yuan / Yang, Wei / Go, Alan S / Parikh, Rishi V / Feldman, Harold I

    JAMA network open

    2021  Volume 4, Issue 7, Page(s) e2117080

    MeSH term(s) Cohort Studies ; Contrast Media ; Correlation of Data ; Cross-Sectional Studies ; Female ; Glomerular Filtration Rate ; Humans ; Iothalamic Acid ; Kidney Function Tests/methods ; Male ; Middle Aged ; Prognosis ; Renal Insufficiency, Chronic/diagnosis ; Statistics as Topic/methods
    Chemical Substances Contrast Media ; Iothalamic Acid (16CHD79MIX)
    Language English
    Publishing date 2021-07-01
    Publishing country United States
    Document type Evaluation Study ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2021.17080
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  9. Article ; Online: Heart failure-type symptom scores in chronic kidney disease: The importance of body mass index.

    Walther, Carl P / Benoit, Julia S / Gregg, L Parker / Bansal, Nisha / Nambi, Vijay / Feldman, Harold I / Shlipak, Michael G / Navaneethan, Sankar D

    International journal of obesity (2005)

    2022  Volume 46, Issue 10, Page(s) 1910–1917

    Abstract: Objectives: This analysis sought to determine factors (including adiposity-related factors) most associated with HF-type symptoms (fatigue, shortness of breath, and edema) in adults with chronic kidney disease (CKD).: Background: Symptom burden ... ...

    Abstract Objectives: This analysis sought to determine factors (including adiposity-related factors) most associated with HF-type symptoms (fatigue, shortness of breath, and edema) in adults with chronic kidney disease (CKD).
    Background: Symptom burden impairs quality of life in CKD, especially symptoms that overlap with HF. These symptoms are common regardless of clinical HF diagnosis, and may be affected by subtle cardiac dysfunction, kidney dysfunction, and other factors. We used machine learning to investigate cross-sectional relationships of clinical variables with symptom scores in a CKD cohort.
    Methods: Participants in the Chronic Renal Insufficiency Cohort (CRIC) with a baseline modified Kansas City Cardiomyopathy Questionnaire (KCCQ) score were included, regardless of prior HF diagnosis. The primary outcome was Overall Summary Score as a continuous measure. Predictors were 99 clinical variables representing demographic, cardiac, kidney and other health dimensions. A correlation filter was applied. Random forest regression models were fitted. Variable importance scores and adjusted predicted outcomes are presented.
    Results: The cohort included 3426 individuals, 10.3% with prior HF diagnosis. BMI was the most important factor, with BMI 24.3 kg/m
    Conclusions: In a CKD cohort, BMI was the most important feature for explaining HF-type symptoms regardless of clinical HF diagnosis, identifying an important focus for symptom directed investigations.
    MeSH term(s) Adult ; Body Mass Index ; Cohort Studies ; Heart Failure/complications ; Heart Failure/epidemiology ; Humans ; Quality of Life ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/epidemiology
    Language English
    Publishing date 2022-08-17
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 752409-2
    ISSN 1476-5497 ; 0307-0565
    ISSN (online) 1476-5497
    ISSN 0307-0565
    DOI 10.1038/s41366-022-01208-x
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  10. Article ; Online: Socioeconomic characteristics of those with peripheral artery disease in the chronic renal insufficiency cohort.

    Stoecker, Jordan B / Cohen, Jordana B / Belkin, Nathan / Chen, Jing C / Townsend, Raymond R / Xie, Dawei / Feldman, Harold I / Wang, Grace J

    Vascular

    2022  Volume 31, Issue 1, Page(s) 39–46

    Abstract: Background: The association between socioeconomic factors and peripheral arterial disease (PAD) has not been as well characterized as other cardiovascular conditions. We sought to define how annual income and education level are associated with PAD in a ...

    Abstract Background: The association between socioeconomic factors and peripheral arterial disease (PAD) has not been as well characterized as other cardiovascular conditions. We sought to define how annual income and education level are associated with PAD in a well-characterized diverse set of adults with chronic kidney disease (CKD).
    Methods: The Chronic Renal Insufficiency Cohort Study (CRIC) is a multi-center, prospective cohort study designed to examine risk factors for progression of CKD and cardiovascular disease. Demographic, income, and education-level data, as well as clinical data including ankle-brachial index (ABI) were collected at baseline. Annual income was categorized as < $25,000, $25,000-50,000, $50,000-100,000, or above $100,000; educational level was categorized as some high school, high school graduate, some college, or college graduate. Participants with missing income data or incompressible ABI (>1.4) were excluded from initial analysis. Logistic regression was used to estimate the association of income and/or education level with PAD, defined as an enrollment ABI of <0.90, history of PAD, or history of PAD intervention.
    Results: A total of 4122 were included, mean age of participants was 59.5 years, 56% were male, and 44% were Black. There were 763 CRIC participants with PAD at study enrollment (18.5%). In the final multivariable logistic regression model, Black race (OR = 1.3, 95% CI 1.1-1.6,
    Conclusions: In this prospectively followed CKD cohort, lower annual household income and Black race were significantly associated with increased PAD at study enrollment. In contrast, educational level was not associated with PAD when adjusted for patient income data. Black race, female gender, and low income were independently associated with decreased statin use, populations which could be targets of future public health programs.
    MeSH term(s) Adult ; Humans ; Male ; Female ; Middle Aged ; Cohort Studies ; Prospective Studies ; Hydroxymethylglutaryl-CoA Reductase Inhibitors ; Peripheral Arterial Disease/diagnosis ; Peripheral Arterial Disease/epidemiology ; Peripheral Arterial Disease/therapy ; Risk Factors ; Ankle Brachial Index/adverse effects ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/therapy ; Socioeconomic Factors
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2022-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2137151-9
    ISSN 1708-539X ; 1708-5381
    ISSN (online) 1708-539X
    ISSN 1708-5381
    DOI 10.1177/17085381211053492
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