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  1. Article: New staging systems in nonmetastatic prostate cancer.

    Feng, Felix

    Clinical advances in hematology & oncology : H&O

    2023  Volume 21, Issue 2, Page(s) 85–87

    MeSH term(s) Male ; Humans ; Prostatic Neoplasms/pathology ; Prostatectomy ; Neoplasm Staging
    Language English
    Publishing date 2023-02-13
    Publishing country United States
    Document type Interview
    ZDB-ID 2271951-9
    ISSN 1543-0790
    ISSN 1543-0790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A new perspective on the treatment of upper ureteric stones.

    Feng, Fu / Xu, Zhanping

    World journal of urology

    2024  Volume 42, Issue 1, Page(s) 66

    MeSH term(s) Humans ; Ureteroscopy ; Ureteral Calculi/therapy ; Urinary Calculi
    Language English
    Publishing date 2024-02-03
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-024-04782-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Preoperative Non-invasive Risk Stratification of Hepatocellular Carcinoma Based on CT.

    Li, Manman / Feng, Feng

    Academic radiology

    2023  Volume 30, Issue 11, Page(s) 2707–2709

    MeSH term(s) Humans ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/surgery ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/surgery ; Liver Neoplasms/pathology ; Tomography, X-Ray Computed ; Retrospective Studies ; Risk Assessment
    Language English
    Publishing date 2023-08-14
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1355509-1
    ISSN 1878-4046 ; 1076-6332
    ISSN (online) 1878-4046
    ISSN 1076-6332
    DOI 10.1016/j.acra.2023.06.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A new member of the structured light family: optical spatiotemporal vortices.

    Feng, Fu / Yuan, Xiaocong

    Light, science & applications

    2023  Volume 12, Issue 1, Page(s) 236

    Abstract: The burgeoning growth of structured light has opened up new possibilities for harnessing the spatiotemporal coupling effects in light. Optical spatiotemporal vortices, as a subset of spatiotemporal light, have emerged as a focal point of recent research, ...

    Abstract The burgeoning growth of structured light has opened up new possibilities for harnessing the spatiotemporal coupling effects in light. Optical spatiotemporal vortices, as a subset of spatiotemporal light, have emerged as a focal point of recent research, owing to their distinctive characteristics and vast range for application. This unique structured light will endow photons with a new degree of freedom, promising to revolutionize researchers' understanding of photonics. Conducting thorough research on optical spatiotemporal vortices will establish a solid foundation for the development of innovative physical mechanisms and advanced applications in photonics.
    Language English
    Publishing date 2023-09-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2662628-7
    ISSN 2047-7538 ; 2047-7538
    ISSN (online) 2047-7538
    ISSN 2047-7538
    DOI 10.1038/s41377-023-01281-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Safety Warning Model Based on IAHA-SVM for Coal Mine Environment.

    Li, Zhen / Feng, Feng

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 14

    Abstract: Coal is an important resource that is closely related to people's lives and plays an irreplaceable role. However, coal mine safety accidents occur from time to time in the process of working underground. Therefore, this paper proposes a coal mine ... ...

    Abstract Coal is an important resource that is closely related to people's lives and plays an irreplaceable role. However, coal mine safety accidents occur from time to time in the process of working underground. Therefore, this paper proposes a coal mine environmental safety early warning model to detect abnormalities and ensure worker safety in a timely manner by assessing the underground climate environment. In this paper, support vector machine (SVM) parameters are optimized using an improved artificial hummingbird algorithm (IAHA), and its safety level is classified by combining various environmental parameters. To address the problems of insufficient global exploration capability and slow convergence of the artificial hummingbird algorithm during iterations, a strategy incorporating Tent chaos mapping and backward learning is used to initialize the population, a Levy flight strategy is introduced to improve the search capability during the guided foraging phase, and a simplex method is introduced to replace the worst value before the end of each iteration of the algorithm. The IAHA-SVM safety warning model is established using the improved algorithm to classify and predict the safety of the coal mine environment as one of four classes. Finally, the performance of the IAHA algorithm and the IAHA-SVM model are simulated separately. The simulation results show that the convergence speed and the search accuracy of the IAHA algorithm are improved and that the performance of the IAHA-SVM model is significantly improved.
    Language English
    Publishing date 2023-07-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23146614
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Reactive Reductive Species Participating Photodynamic Therapy for Cancer Treatment.

    Peng, Jinlei / Feng, Fude

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2023  Volume 30, Issue 1, Page(s) e202302842

    Abstract: Although the development of oxidative photodynamic therapy (O-PDT) based on reactive oxygen species (ROS) has led to great progress in cancer treatment, tumor hypoxia, cellular adaptation and intrinsic antioxidant defenses are still obstacles at this ... ...

    Abstract Although the development of oxidative photodynamic therapy (O-PDT) based on reactive oxygen species (ROS) has led to great progress in cancer treatment, tumor hypoxia, cellular adaptation and intrinsic antioxidant defenses are still obstacles at this stage. Fortunately, with the discovery and development of reactive reductive species (RRS) in the PDT process, reductive PDT (R-PDT) is receiving increasing research interest. R-PDT with oxygen-independence is an effective reduction therapy that promises excellent therapeutic efficacy in extremely hypoxic or even anaerobic environments. In the concept, we introduce representative strategies to boost the type-I photosensitizing pathway, and then focus on the most recent R-PDT involving hydrogen radical (H⋅) and the single electron transfer (SET) process.
    MeSH term(s) Humans ; Photochemotherapy ; Photosensitizing Agents/pharmacology ; Photosensitizing Agents/therapeutic use ; Reactive Oxygen Species/metabolism ; Oxygen ; Hypoxia ; Cell Line, Tumor ; Neoplasms/drug therapy
    Chemical Substances Photosensitizing Agents ; Reactive Oxygen Species ; Oxygen (S88TT14065)
    Language English
    Publishing date 2023-11-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-X
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.202302842
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Structural Description of Chiral E-Tiling DNA Nanotubes with the Chiral Indices (n,m) and Handedness Defined by Microscopic Imaging.

    Feng, Feiyang / Xiao, Shou-Jun

    Chembiochem : a European journal of chemical biology

    2023  Volume 24, Issue 22, Page(s) e202300460

    Abstract: In structural DNA nanotechnology, E-tiling DNA nanotubes are evidenced to be homogeneous in diameter and thus have great potential in biomedical applications such as cellular transport and communication, transmembrane ion/molecule channeling, and drug ... ...

    Abstract In structural DNA nanotechnology, E-tiling DNA nanotubes are evidenced to be homogeneous in diameter and thus have great potential in biomedical applications such as cellular transport and communication, transmembrane ion/molecule channeling, and drug delivery. However, a precise structural description of chiral DNA nanotubes with chiral parameters was lacking, thus greatly hindering their application breadth and depth, until we recently raised and partly solved this problem. In this perspective, we summarize recent progress in defining the chiral indices and handedness of E-tiling DNA nanotubes by microscopic imaging, especially atomic force microscopy (AFM) imaging. Such a detailed understanding of the chiral structures of E-tiling DNA nanotubes will be very helpful in the future, on the one hand for engineering DNA nanostructures precisely, and, on the other, for realizing specific physicochemical properties and biological functions successfully.
    MeSH term(s) Functional Laterality ; Nanotubes/chemistry ; Nanotechnology/methods ; Nanostructures/chemistry ; DNA/chemistry ; Microscopy, Atomic Force/methods
    Chemical Substances DNA (9007-49-2)
    Language English
    Publishing date 2023-09-07
    Publishing country Germany
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2020469-3
    ISSN 1439-7633 ; 1439-4227
    ISSN (online) 1439-7633
    ISSN 1439-4227
    DOI 10.1002/cbic.202300460
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  8. Article ; Online: Ferroptosis and Pyroptosis in Epilepsy.

    Feng, Fan / Luo, Rong / Mu, Dezhi / Cai, Qianyun

    Molecular neurobiology

    2024  

    Abstract: Epilepsy is sudden, recurrent, and transient central nervous system dysfunction caused by abnormal discharge of neurons in the brain. Ferroptosis and pyroptosis are newly discovered ways of programmed cell death. One of the characteristics of ferroptosis ...

    Abstract Epilepsy is sudden, recurrent, and transient central nervous system dysfunction caused by abnormal discharge of neurons in the brain. Ferroptosis and pyroptosis are newly discovered ways of programmed cell death. One of the characteristics of ferroptosis is the oxidative stress generated by lipid peroxides. Similarly, pyroptosis has unique pro-inflammatory properties. As both oxidative stress and neuroinflammation are significant contributors to the pathogenesis of epilepsy, increasing evidence shows that ferroptosis and pyroptosis are closely related to epilepsy. This article reviews the current comprehension of ferroptosis and pyroptosis and elucidates potential mechanisms by which ferroptosis and pyroptosis may contribute to epilepsy. In addition, we also highlight the possible interactions between ferroptosis and pyroptosis because they reportedly coexist in many diseases, and increasing studies have demonstrated the convergence of pathways between the two. This is of great significance for explaining the occurrence and development of epilepsy and provides a new therapeutic perspective for the treatment of epilepsy.
    Language English
    Publishing date 2024-02-21
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645020-9
    ISSN 1559-1182 ; 0893-7648
    ISSN (online) 1559-1182
    ISSN 0893-7648
    DOI 10.1007/s12035-024-04018-6
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  9. Article ; Online: Polymer-Drug Conjugates Codeliver a Temozolomide Intermediate and Nitric Oxide for Enhanced Chemotherapy against Glioblastoma Multiforme.

    Du, Ke / Li, Xiao / Feng, Fude

    ACS applied bio materials

    2024  Volume 7, Issue 3, Page(s) 1810–1819

    Abstract: Polymer-drug conjugates (PDCs) provide possibilities for the development of multiresponsive drug delivery and release platforms utilized in cancer therapy. The delivery of Temozolomide (TMZ, a DNA methylation agent) by PDCs has been developed to improve ... ...

    Abstract Polymer-drug conjugates (PDCs) provide possibilities for the development of multiresponsive drug delivery and release platforms utilized in cancer therapy. The delivery of Temozolomide (TMZ, a DNA methylation agent) by PDCs has been developed to improve TMZ stability under physiological conditions for the treatment of glioblastoma multiforme (GBM); however, with inefficient chemotherapeutic efficacy. In this work, we synthesized an amphiphilic triblock copolymer (P1-SNO) with four pendant functionalities, including (1) a TMZ intermediate (named MTIC) as a prodrug moiety, (2) a disulfide bond as a redox-responsive trigger to cage MTIC, (3) S-nitrosothiol as a light/heat-responsive donor of nitric oxide (NO), and (4) a poly(ethylene glycol) chain to enable self-assembly in aqueous media. P1-SNO was demonstrated to liberate MTIC in the presence of reduced glutathione and release gaseous NO upon exposure to light or heat. The in vitro results revealed a synergistic effect of released MTIC and NO on both TMZ-sensitive and TMZ-resistant GBM cells. The environment-responsive PDC system for codelivery of MTIC and NO is promising to overcome the efficacy issue in TMZ-based cancer therapy.
    MeSH term(s) Humans ; Temozolomide/pharmacology ; Temozolomide/chemistry ; Glioblastoma/drug therapy ; Nitric Oxide ; Polymers ; Antineoplastic Agents, Alkylating/pharmacology ; Antineoplastic Agents, Alkylating/therapeutic use ; Prodrugs/pharmacology ; Prodrugs/therapeutic use ; Dacarbazine/analogs & derivatives
    Chemical Substances Temozolomide (YF1K15M17Y) ; Nitric Oxide (31C4KY9ESH) ; 5-(3-methyl-1-triazeno)imidazole-4-carboxamide (PYY6H17XIV) ; Polymers ; Antineoplastic Agents, Alkylating ; Prodrugs ; Dacarbazine (7GR28W0FJI)
    Language English
    Publishing date 2024-02-25
    Publishing country United States
    Document type Journal Article
    ISSN 2576-6422
    ISSN (online) 2576-6422
    DOI 10.1021/acsabm.3c01219
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  10. Article: Root morphology and physiological of their relationship with nitrogen uptake in wheat (

    Qu, Bo / Feng, Fujie / Di, Jun / Noor, Hafeez

    Heliyon

    2024  Volume 10, Issue 8, Page(s) e29283

    Abstract: Nitrogen (N) application is believed to improve photosynthesis in flag leaf ultimately increase final yield. The main results at 20-30 days after anthesis, the activities of superoxide dismutase (SOD) and peroxidase (POD) and soluble protein in flag ... ...

    Abstract Nitrogen (N) application is believed to improve photosynthesis in flag leaf ultimately increase final yield. The main results at 20-30 days after anthesis, the activities of superoxide dismutase (SOD) and peroxidase (POD) and soluble protein in flag leaves of N150 were found to be the most effective. Increased root weight density, root length density and root volume density at flowering stage, up to 10.6 %, 15.0 %, respectively. The root weight density, root length density and root bulk density at flowering and mature stages were the highest at the N180. Delaying the senescence physiology of post flowering leaves in the middle, and late stage, photosynthesis of leaves in the middle and late stage, improving the light energy interception of wheat, and then improving the light energy utilization efficiency. The stomatal conductance of flag leaves 15-30 days after anthesis, the maximum potential photochemical efficiency 20-30 days after anthesis, and the photochemical quenching of flag leaves 25-30 days after anthesis, and improved the light energy utilization efficiency by 9.6%-11.1 %. Yunhan-20410 the gene expressions of
    Language English
    Publishing date 2024-04-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e29283
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