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  1. Article ; Online: Analysis of Related Influencing Factors of Portal Vein Thrombosis After Hepatectomy.

    Qi, ShiGuai / Tao, Jie / Wu, Xinhua / Feng, Xu / Feng, Guoying / Shi, Zhengrong

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2024  Volume 34, Issue 3, Page(s) 246–250

    Abstract: Purpose: ...

    Abstract Purpose:
    MeSH term(s) Humans ; Portal Vein/pathology ; Fibrin Fibrinogen Degradation Products ; Hepatectomy/adverse effects ; Retrospective Studies ; Ascites/etiology ; Liver Cirrhosis/complications ; Liver Cirrhosis/surgery ; Liver Cirrhosis/pathology ; Risk Factors ; Venous Thrombosis/etiology ; Venous Thrombosis/surgery ; Albumins
    Chemical Substances Fibrin Fibrinogen Degradation Products ; Albumins
    Language English
    Publishing date 2024-01-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2023.0455
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Novel Closed-Loop Control to Solve Light Source Power Fluctuations in the Fiber-Optic Gyroscope.

    Zheng, Shijie / Ren, Mengyu / Luo, Xin / Zhang, Hangyu / Feng, Guoying

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 10

    Abstract: The performance of a gyroscope is directly affected by the fluctuations in the light source power (LSP) in an interferometric fiber-optic gyroscope (IFOG). Therefore, it is important to compensate for fluctuations in the LSP. When the feedback phase ... ...

    Abstract The performance of a gyroscope is directly affected by the fluctuations in the light source power (LSP) in an interferometric fiber-optic gyroscope (IFOG). Therefore, it is important to compensate for fluctuations in the LSP. When the feedback phase generated by the step wave completely cancels the Sagnac phase in real-time, the error signal of the gyroscope is linearly related to the differential signal of the LSP, otherwise, the error signal of the gyroscope is uncertain. Herein, we present two compensation methods to compensate for the error of the gyroscope when the error is uncertain, which are double period modulation (DPM) and triple period modulation (TPM). Compared with the TPM, DPM has better performance, but it increases the requirements for the circuit. TPM has lower requirements for the circuit and is more suitable for small fiber- coil applications. The experimental results show that, when the frequency of the LSP fluctuation is relatively low (1 kHz and 2 kHz), DPM and TPM do not differ significantly in terms of performance; both of them can achieve an improvement of about 95% in bias stability. When the frequency of the LSP fluctuation is relatively high (4 kHz, 8 kHz and 16 kHz), DPM and TPM can achieve about 95% and 88% improvement in bias stability, respectively.
    Language English
    Publishing date 2023-05-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23104590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Real-Time Compensation for SLD Light-Power Fluctuation in an Interferometric Fiber-Optic Gyroscope.

    Zheng, Shijie / Ren, Mengyu / Luo, Xin / Zhang, Hangyu / Feng, Guoying

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 4

    Abstract: An interferometric fiber-optic gyroscope (IFOG) demodulates a rotation signal via interferometric light intensity. However, the working environments of IFOGs typically involve great uncertainty. Fluctuations in temperature, air pressure, electromagnetic ... ...

    Abstract An interferometric fiber-optic gyroscope (IFOG) demodulates a rotation signal via interferometric light intensity. However, the working environments of IFOGs typically involve great uncertainty. Fluctuations in temperature, air pressure, electromagnetic field, and the power system all cause the power of the superluminescent diode (SLD) light source to fluctuate as well. In this invited paper, we studied the effects of SLD power fluctuation on the dynamic and static performance characteristics of a gyro system through the use of a light-power feedback loop. Fluctuations of 0.5 mA, 1 mA, and 5 mA in the SLD source entering the IFOG caused zero-bias stability to be 69, 135, and 679 times worse. We established an effective method to monitor power fluctuations of SLD light sources and to compensate for their effects without increasing hardware complexity or system cost. In brief, we established a real-time power-sensing and -compensating system. Experimental results showed that for every 0.1 mA increase in the fluctuation amplitude of the driving current, the zero-bias stability became 4 to 7 times worse, which could be reduced about 95% through the use of SLD power compensation.
    Language English
    Publishing date 2023-02-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23041925
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tailoring the performance of composite PEI nanofiltration membranes via incorporating activated cyclodextrins.

    Hu, Dujuan / Feng, Guoying / Xu, Man / Wang, Cunwen / Li, Yanbo

    Chemosphere

    2023  Volume 342, Page(s) 140180

    Abstract: Cyclodextrins (CDs) with unique cavity structures have been used as materials for nanofiltration membrane fabrications. In the present work, the activated CD (O-CD), oxidated by ... ...

    Abstract Cyclodextrins (CDs) with unique cavity structures have been used as materials for nanofiltration membrane fabrications. In the present work, the activated CD (O-CD), oxidated by NaIO
    MeSH term(s) Cyclodextrins/chemistry ; Polyethyleneimine/chemistry ; Polymers ; Filtration ; Molecular Weight
    Chemical Substances Cyclodextrins ; Polyethyleneimine (9002-98-6) ; Polymers
    Language English
    Publishing date 2023-09-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2023.140180
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Moving grating-based laser heterodyne digital holographic microscopy system for measuring dynamic phase of living cell attachment.

    Wang, Peng / Wu, Shizhou / Zhang, Xia / Qin, Boquan / Feng, Guoying

    Journal of biophotonics

    2023  Volume 17, Issue 3, Page(s) e202300355

    Abstract: We propose a laser heterodyne digital holography microscopy system based on a moving grating, which uses the Doppler principle between a moving grating and beam to achieve a low-frequency bias between the diffracted beams, abandoning traditional ... ...

    Abstract We propose a laser heterodyne digital holography microscopy system based on a moving grating, which uses the Doppler principle between a moving grating and beam to achieve a low-frequency bias between the diffracted beams, abandoning traditional heterodyne digital holography that requires multiple acousto-optic modulators. The dynamic phase distribution obtained using the laser heterodyne digital holography phase-reconstruction algorithm was more realistic and analyzable than the results of the angular spectrum algorithm. The structure and algorithm were used to capture the shape characteristics of mouse fibroblasts after ~2 h of incubation (37°C, 5% CO
    MeSH term(s) Mice ; Animals ; Holography/methods ; Quantitative Phase Imaging ; Microscopy/methods ; Light ; Eye
    Language English
    Publishing date 2023-12-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2390063-5
    ISSN 1864-0648 ; 1864-063X
    ISSN (online) 1864-0648
    ISSN 1864-063X
    DOI 10.1002/jbio.202300355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Serum response factor promoting axonal regeneration by activating the Ras-Raf-Cofilin signaling pathway after the spinal cord injury.

    Gao, Limin / Zhang, Chen / Zhu, Yonglin / Zhang, Naili / Zhang, Chunlei / Zhou, Shuai / Feng, Guoying / Huang, Fei / Zhang, Luping

    CNS neuroscience & therapeutics

    2024  Volume 30, Issue 2, Page(s) e14585

    Abstract: Introduction: Serum response factor (SRF) is important in muscle development, tissue repair, and neuronal regulation.: Objectives: This research aims to thoroughly examine the effects of SRF on spinal cord injury (SCI) and its ability to ... ...

    Abstract Introduction: Serum response factor (SRF) is important in muscle development, tissue repair, and neuronal regulation.
    Objectives: This research aims to thoroughly examine the effects of SRF on spinal cord injury (SCI) and its ability to significantly impact the recovery and regeneration of neuronal axons.
    Methods: The researchers created rat models of SCI and scratch injury to primary spinal cord neurons to observe the expression of relevant factors after neuronal injury.
    Results: We found that the SRF, Ras, Raf, and cofilin levels increased after injury and gradually returned to normal levels. Afterward, researchers gave rats with SCI an SRF inhibitor (CCG1423) and studied the effects with nuclear magnetic resonance and transmission electron microscopy. The SRF inhibitor rodents had worse spinal cord recovery and axon regrowth than the control group. And the apoptosis of primary neurons after scratch injury was significantly higher in the SRF inhibitor group. Additionally, the researchers utilized lentiviral transfection to modify the SRF expression in neurons. SRF overexpression increased neuron migration while silencing SRF decreased it. Finally, Western blotting and RT-PCR were conducted to examine the expression changes of related factors upon altering SRF expression. The results revealed SRF overexpression increased Ras, Raf, and cofilin expression. Silencing SRF decreased Ras, Raf, and Cofilin expression.
    Conclusion: Based on our research, the SRF promotes axonal regeneration by activating the "Ras-Raf-Cofilin" signaling pathway.
    MeSH term(s) Rats ; Animals ; Actin Depolymerizing Factors/metabolism ; Actin Depolymerizing Factors/pharmacology ; Serum Response Factor/genetics ; Serum Response Factor/metabolism ; Serum Response Factor/pharmacology ; Spinal Cord Injuries/pathology ; Neurons/metabolism ; Axons ; Spinal Cord/metabolism ; Signal Transduction ; Nerve Regeneration ; Recovery of Function/physiology
    Chemical Substances Actin Depolymerizing Factors ; Serum Response Factor
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2423461-8
    ISSN 1755-5949 ; 1755-5930
    ISSN (online) 1755-5949
    ISSN 1755-5930
    DOI 10.1111/cns.14585
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Size Effect of Electrical and Optical Properties in Cr

    Zhang, Yuqin / He, Shi / Yao, Honghong / Zuo, Hao / Liu, Shuang / Yang, Chao / Feng, Guoying

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 2

    Abstract: Previous studies have shown that the nano-crystallization process has an appreciable impact on the luminescence properties of nanocrystals, which determines their defect state composition, size and morphology. This project aims to explore the influence ... ...

    Abstract Previous studies have shown that the nano-crystallization process has an appreciable impact on the luminescence properties of nanocrystals, which determines their defect state composition, size and morphology. This project aims to explore the influence of nanocrystal size on the electrical and optical properties of Cr
    Language English
    Publishing date 2023-01-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13020369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Correlation between Immunohistochemical Markers in Hepatocellular Carcinoma Cells and

    Feng, Guo-Ying / Cheng, Yu / Chen, Kai / Shi, Zheng-Rong

    Canadian journal of gastroenterology & hepatology

    2022  Volume 2022, Page(s) 5969716

    Abstract: Aim: This study analyzed the correlation between immunohistochemical markers in hepatocellular carcinoma cells and the results of : Methods: Seventy-four patients with hepatocellular carcinoma were included in this study from December 2019 to June ... ...

    Abstract Aim: This study analyzed the correlation between immunohistochemical markers in hepatocellular carcinoma cells and the results of
    Methods: Seventy-four patients with hepatocellular carcinoma were included in this study from December 2019 to June 2021, and their liver cancer cells were used for
    Results: Alpha-fetoprotein (AFP)-positive liver cancer cells were significantly more sensitive to gemcitabine than AFP-negative cells (
    Conclusion: Gemcitabine and L-OHP + EPI + irinotecan + 5-FU, L-OHP + EPI, and L-OHP + irinotecan + EPI were more effective against AFP-positive compared with AFP-negative liver cancer cells according to
    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/etiology ; Fluorouracil/pharmacology ; Humans ; Irinotecan/therapeutic use ; Liver Neoplasms/drug therapy ; Liver Neoplasms/etiology ; Oxaliplatin ; alpha-Fetoproteins
    Chemical Substances alpha-Fetoproteins ; Oxaliplatin (04ZR38536J) ; Irinotecan (7673326042) ; Fluorouracil (U3P01618RT)
    Language English
    Publishing date 2022-01-25
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2762182-0
    ISSN 2291-2797 ; 1916-7237 ; 0835-7900
    ISSN (online) 2291-2797 ; 1916-7237
    ISSN 0835-7900
    DOI 10.1155/2022/5969716
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Antisense yycF and BMP-2 co-delivery gelatin methacryloyl and carboxymethyl chitosan hydrogel composite for infective bone defects regeneration.

    Qin, Boquan / Dong, Hongxian / Tang, Xiaofang / Liu, Yunjie / Feng, Guoying / Wu, Shizhou / Zhang, Hui

    International journal of biological macromolecules

    2023  Volume 253, Issue Pt 5, Page(s) 127233

    Abstract: Repairing infected bone defects remains a challenge in clinical work. Intractable bacterial infections and insufficient osseointegration are major concerns for infected bone defects. To address these issues, we developed a gelatin methacryloyl (GelMA) ... ...

    Abstract Repairing infected bone defects remains a challenge in clinical work. Intractable bacterial infections and insufficient osseointegration are major concerns for infected bone defects. To address these issues, we developed a gelatin methacryloyl (GelMA) and carboxymethyl chitosan (CMCS) composite hydrogel with BMP-2 growth factor and GO based antisense technology supported by a PLGA spring. In vitro, photo-crosslinked GelMA composite hydrogels shown excellent biocompatibility and degradability. Relying on the release of BMP-2 from the composite hydrogel provides osteogenic effects. The antisense yycF and BMP-2 were released with the degradation of GelMA and CMCS composite hydrogel. In terms of antimicrobial properties, CMCS, GO and post-transcriptional regulatory antisense yycF from the composite hydrogel synergistically kill S. aureus. In vivo, we implanted the composite hydrogel in a rat model of S. aureus infected femur defect, effectively accelerating bone healing in an infectious microenvironment. This research provides a novel biomaterial that is both antimicrobial and promotes bone regeneration, with the potential to treat infected bone defects.
    MeSH term(s) Rats ; Animals ; Hydrogels/pharmacology ; Chitosan/pharmacology ; Staphylococcus aureus ; Bone Regeneration ; Gelatin/pharmacology ; Anti-Infective Agents/pharmacology
    Chemical Substances Hydrogels ; Chitosan (9012-76-4) ; gelatin methacryloyl ; Gelatin (9000-70-8) ; Anti-Infective Agents
    Language English
    Publishing date 2023-10-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.127233
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Autoimmune regulator (Aire) deficiency results in reduced memory CD8+ T cells after Listeria monocytogenes infection in a murine model

    Feng, Yi / Yao, Shu / Li, Shan / Peng, Zuxiang / Feng, Guoying / Ma, Yan / Guo, Bo / Liu, Hongming

    FEBS Letters. 2023 Sept., v. 597, no. 17 p.2185-2195

    2023  

    Abstract: Homozygous mutations in the autoimmune regulator (AIRE) gene that cripple thymic negative selection of autoreactive T cells result in autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy (APECED). However, how AIRE regulates the T‐cell response ...

    Abstract Homozygous mutations in the autoimmune regulator (AIRE) gene that cripple thymic negative selection of autoreactive T cells result in autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy (APECED). However, how AIRE regulates the T‐cell response against foreign pathogens is not well understood. Here, we observed comparable primary CD8⁺ T cells but a markedly reduced memory T‐cell population and protective function in Aire⁻/⁻ mice compared with wild‐type after infection with a strain of recombinant Listeria monocytogenes. In adoptive transfer models, exogenous congenic CD8⁺ T cells transferred into Aire⁻/⁻ mice also showed a reduction in the memory T‐cell population, indicating an important role for extrathymic Aire‐expressing cells in shaping or sustaining memory T cells. Moreover, using a bone marrow chimeric model, we found that Aire expressed in radioresistant cells plays an important role in maintaining the memory phenotype. These results provide important insights into the role of extrathymic Aire in the T‐cell response to infection.
    Keywords Listeria monocytogenes ; T-lymphocytes ; animal models ; bone marrow ; genes ; homozygosity ; memory ; phenotype ; radiation resistance
    Language English
    Dates of publication 2023-09
    Size p. 2185-2195.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 212746-5
    ISSN 1873-3468 ; 0014-5793
    ISSN (online) 1873-3468
    ISSN 0014-5793
    DOI 10.1002/1873-3468.14696
    Database NAL-Catalogue (AGRICOLA)

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