Article ; Online: An Investigation of the Effects of
Biomedical and environmental sciences : BES
2023 Volume 36, Issue 9, Page(s) 814–825
Abstract: Objective: To investigate the effects of the : Methods: A total of 1,490 cancer patients (lung/gastric/liver/: 550/460/480) and 800 controls were recruited in this case-control study. The meta-analysis was performed by pooling the data from previous ... ...
Abstract | Objective: To investigate the effects of the Methods: A total of 1,490 cancer patients (lung/gastric/liver/: 550/460/480) and 800 controls were recruited in this case-control study. The meta-analysis was performed by pooling the data from previous related studies and the present study. Results: The results of this study showed that in the Hubei Han Chinese population, the rs10754339 gene was significantly associated with the risk of lung and gastric cancer but not liver cancer, and the rs12976445 gene was significantly associated with the risk of lung cancer but not liver or gastric cancer. The meta-analysis results indicated that rs10754339 and rs12976445 contributed to cancer susceptibility in the Chinese population and also revealed a significant association between rs10754339 and breast cancer risk, as well as between rs12976445 and lung cancer risk. Conclusion: The |
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MeSH term(s) | Humans ; MicroRNAs/genetics ; Stomach Neoplasms/genetics ; Case-Control Studies ; Lung Neoplasms/genetics ; Risk |
Chemical Substances | MicroRNAs |
Language | English |
Publishing date | 2023-10-06 |
Publishing country | China |
Document type | Meta-Analysis ; Journal Article |
ZDB-ID | 645083-0 |
ISSN | 2214-0190 ; 0895-3988 |
ISSN (online) | 2214-0190 |
ISSN | 0895-3988 |
DOI | 10.3967/bes2023.074 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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