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Article ; Online: Botulinum toxin injection for chronic anal fissure: a prospective controlled study with long follow-up.

Ascanelli, Simona / Rossin, Eleonora / Aisoni, Filippo / Sette, Elisabetta / Chimisso, Laura / Valpiani, Giorgia / Costanzini, Anna / DE Giorgio, Roberto / Feo, Carlo V

Minerva surgery

2024

Abstract: Background: Botulinum toxin is an effective therapeutic option for chronic anal fissure. However, there is no evidence about treatment standardization and long-term follow-up. We aimed to evaluate the short- and long-term efficacy and safety of ... ...

Abstract	Background: Botulinum toxin is an effective therapeutic option for chronic anal fissure. However, there is no evidence about treatment standardization and long-term follow-up. We aimed to evaluate the short- and long-term efficacy and safety of botulinum toxin compared to close lateral internal sphincterotomy, with a 5-year follow-up. Methods: This was a prospective, controlled, single-center study conducted at University Hospital of Ferrara, Ferrara, Italy. The primary outcome was fissure healing at 1 month. Secondary outcomes were Quality-of-Life (QoL) at 1 month and after 5 years, and fissure recurrence at 6 months and 5 years. Results: A total of 59 patients received botulinum toxin injection (Botox), and 32 underwent lateral internal sphincterotomy. At 1 month after treatments, postoperative pain decreased faster and significantly more in the Botox group (30 vs. 60 mm; P<0.001); fissure re-epithelization was observed in 59.4% of the surgical group compared to 25.4% of Botox (P=0.0001). Anal sphincter pressures decreased more in surgical group (P=0.044), although severe anal incontinence was present only in this subset (6.2%; P=0.041). Compared to surgery, patients who received Botox had higher satisfaction rates (P<0.001). Fissure recurrence at 6 months was more common in Botox than surgical group (16.9% vs. 3.2%, respectively; P=0.053). The overall healing rate improved in all patients and persisted at 12 months and 5 years in both groups with overall high patient satisfaction despite mild anal incontinence in 21.8% in the surgery group (P<0.05). Conclusions: Botox, rather than surgery, should be considered the first-line treatment for chronic anal fissure.
Language	English
Publishing date	2024-03-29
Publishing country	Italy
Document type	Journal Article
ZDB-ID	3067899-7
ISSN	2724-5438
ISSN (online)	2724-5438
DOI	10.23736/S2724-5691.24.10228-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Berne-Donovan technique for diverticulization of a severe lateral non-traumatic duodenal fistula.

Pesce, Antonio / Fabbri, Nicolò / Tilli, Massimo / Bertasi, Mario / Feo, Carlo V

Annali italiani di chirurgia

2022 Volume 92, Page(s) 344–348

Abstract: Background: The duodenal «diverticulization» is a surgical technique described by Berne and colleagues in 1968 for the treatment of combined duodenal pancreatic injuries. It consisted of closure of the duodenal injury by suture and tube duodenostomy, ... ...

Abstract	Background: The duodenal «diverticulization» is a surgical technique described by Berne and colleagues in 1968 for the treatment of combined duodenal pancreatic injuries. It consisted of closure of the duodenal injury by suture and tube duodenostomy, gastric antrectomy with end-to-side isoperistaltic Billroth II gastrojejunostomy, and abdominal drainage. As evidenced from the literature in few reports, this technique has also been adopted for lateral duodenal lacerations in non traumatic conditions. Most biliary disease may be responsible for duodenal injury. Case presentation: Herein, we describe the application of this emergency technique for the treatment of a wide lateral duodenal laceration discovered intra-operatively during laparoscopic cholecystectomy for acute cholecystitis. A comprehensive critical review of the different surgical methods proposed for duodenal protection in case of severe duodenal lesions has been performed and discussed. Conclusion: Duodenal injuries represent a challenging condition, especially for surgeons with limited experience in this field. The key-message of this report is to consider emergency surgical techniques in difficult unexpected intra-operative situations which may occur during routine surgical practice. Key words: Duodenal diverticulization, Duodenal fistula, Laparoscopic cholecystectomy, Surgical repair.
MeSH term(s)	Cholecystectomy, Laparoscopic ; Duodenal Diseases/surgery ; Duodenostomy ; Duodenum/surgery ; Humans ; Intestinal Fistula/etiology ; Intestinal Fistula/surgery
Language	English
Publishing date	2022-09-03
Publishing country	Italy
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
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Article: A rare case of jejunal Vanek's tumor causing intussusception in an adult: a case report and comprehensive literature overview.

Fabbri, Nicolò / Rimi, Francesco / Sani, Valentina / Pesce, Antonio / Greco, Salvatore / Gobbo, Stefano / Feo, Carlo V

Journal of surgical case reports

2023 Volume 2023, Issue 12, Page(s) rjad642

Abstract: Inflammatory fibroid polyp, or Vanek's tumor, is an uncommon benign small bowel tumor and a rare cause of intussusception in adults. This case involves a 62-year-old man with persistent abdominal pain, diagnosed with jejunoileal intussusception. A 4 cm ... ...

Abstract	Inflammatory fibroid polyp, or Vanek's tumor, is an uncommon benign small bowel tumor and a rare cause of intussusception in adults. This case involves a 62-year-old man with persistent abdominal pain, diagnosed with jejunoileal intussusception. A 4 cm inflammatory fibroid polyp was discovered during surgery, leading to distal jejunal resection. Despite the rarity of adult intussusceptions, they should be considered in abdominal pain diagnoses. The optimal management approach, whether
Language	English
Publishing date	2023-12-05
Publishing country	England
Document type	Case Reports
ZDB-ID	2580919-2
ISSN	2042-8812
ISSN	2042-8812
DOI	10.1093/jscr/rjad642
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Article ; Online: Predictive Factors of Recurrence After Laparoscopic Incisional Hernia Repair: A Retrospective Multicentre Cohort Study.

Soliani, Giorgio / De Troia, Alessandro / Pesce, Antonio / Portinari, Mattia / Fabbri, Nicolò / Leonardi, Luca / Neri, Silvia / Carcoforo, Paolo / Feo, Carlo V

Journal of laparoendoscopic & advanced surgical techniques. Part A

2023 Volume 33, Issue 5, Page(s) 427–433

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Humans ; Incisional Hernia/surgery ; Cohort Studies ; Retrospective Studies ; Laparoscopy/methods ; Herniorrhaphy/methods ; Surgical Mesh ; Hernia, Ventral/surgery
Language	English
Publishing date	2023-01-20
Publishing country	United States
Document type	Multicenter Study ; Journal Article
ZDB-ID	1381909-4
ISSN	1557-9034 ; 1092-6429
ISSN (online)	1557-9034
ISSN	1092-6429
DOI	10.1089/lap.2022.0465
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Article ; Online: Acute Esophageal Necrosis as a Rare Complication of Metabolic Acidosis in a Diabetic Patient: A Case Report.

Greco, Salvatore / Giovine, Antonio / Rocchi, Cindy / Resca, Riccardo / Bigoni, Renato / Formigaro, Luca / Angeletti, Anna Grazia / Fabbri, Nicolò / Bonazza, Aurora / Feo, Carlo V

The American journal of case reports

2023 Volume 24, Page(s) e939624

Abstract: BACKGROUND Acute esophageal necrosis, or Gurvits syndrome, is a rare clinical process often secondary to a systemic low-flow state. It can be caused by several medical conditions, and it is thought to arise from a combination of impaired mucosal barrier ... ...

Abstract	BACKGROUND Acute esophageal necrosis, or Gurvits syndrome, is a rare clinical process often secondary to a systemic low-flow state. It can be caused by several medical conditions, and it is thought to arise from a combination of impaired mucosal barrier and chemical and ischemic insults to the esophagus. Acute esophageal necrosis usually presents with severe complications due to delayed diagnosis and only rarely has surgical indications. We present a case of Gurvits syndrome, presumably triggered by metabolic acidosis in a diabetic patient. CASE REPORT A 61-year-old man with history of hypertension and type 2 diabetes mellitus treated with metformin, canagliflozin, glimepiride, and pioglitazone came to our attention with persistent vomiting, odynophagia, chest pain after each meal, and progressive weight loss. Arterial blood analysis showed mild metabolic acidosis, while the first esophagogastroduodenoscopy performed revealed a circumferential black appearance of the esophageal mucosa, as in concentric necrosis of the distal esophagus with possible fungal superinfection. Brushing cytology confirmed the infection by Candida spp. and the patient was treated with intravenous fluconazole. The second esophagogastroduodenoscopy, performed after 2 weeks, showed almost complete healing of the esophageal mucosa; in this case, biopsy confirmed mucosal ischemia and necrosis, without showing deep impairment of the mucosa by fungal agents. CONCLUSIONS Due to its high lethality, often caused by the underlying medical diseases, acute esophageal disease should be considered in the differential diagnosis of digestive symptoms, even without upper gastrointestinal bleeding. Prompt diagnosis and treatment of contextual collateral conditions can help clinicians to avoid the worst outcomes of the disease. Among the causative factors of metabolic acidosis leading to esophageal necrosis we recognized metformin and dapagliflozin.
MeSH term(s)	Humans ; Male ; Middle Aged ; Acidosis/complications ; Diabetes Mellitus, Type 2/drug therapy ; Esophageal Diseases/diagnosis ; Esophageal Diseases/etiology ; Necrosis ; Acute Disease
Language	English
Publishing date	2023-08-15
Publishing country	United States
Document type	Case Reports
ZDB-ID	2517183-5
ISSN	1941-5923 ; 1941-5923
ISSN (online)	1941-5923
ISSN	1941-5923
DOI	10.12659/AJCR.939624
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Laparoscopic treatment of colo-colic intussusception secondary to a lipomatous polyp.

Feo, Carlo V / Marcello, Daniele / Feo, Claudio F

Annali italiani di chirurgia

2017 Volume 6

Abstract: Introduction: Colo-colic intussusception is extremely rare in adults and few cases have been described secondary to a lypomatous polyp.: Case report: We present the case of a 50-year old man with chronic abdominal pain who was diagnosed a colo-colic ... ...

Abstract	Introduction: Colo-colic intussusception is extremely rare in adults and few cases have been described secondary to a lypomatous polyp. Case report: We present the case of a 50-year old man with chronic abdominal pain who was diagnosed a colo-colic intussusception secondary to a lipoma of the left colon. The patient underwent laparoscopic resection of the splenic flexure without reduction, which occurred spontaneously after induction of the pneumoperitoneum, and final histology confirmed a submucosal lipoma with no evidence of malignancy. Conclusion: The traditional treatment of choice for adult intussusception is bowel resection without reduction. More recently, however, preoperative reduction of the invaginated bowel segment has been reconsidered in order to: 1) avoid emergency surgery, 2) allow radical surgery for cancer, and 3) reduce the extent of the intestinal resection. To the best of our knowledge, this is the first case of adult colonic intussusception secondary to a lipoma treated by laparoscopy. Key words: Colon, Intussusception, Laparoscopy, Lipoma.
MeSH term(s)	Abdominal Pain/etiology ; Colonic Diseases/diagnostic imaging ; Colonic Diseases/etiology ; Colonic Diseases/surgery ; Colonic Neoplasms/complications ; Colonic Neoplasms/diagnostic imaging ; Colonic Neoplasms/surgery ; Colonic Polyps/complications ; Colonic Polyps/diagnostic imaging ; Colonic Polyps/pathology ; Colonic Polyps/surgery ; Colonoscopy ; Humans ; Intussusception/diagnostic imaging ; Intussusception/etiology ; Intussusception/surgery ; Laparoscopy/methods ; Lipoma/complications ; Lipoma/diagnostic imaging ; Lipoma/surgery ; Male ; Middle Aged ; Tomography, X-Ray Computed
Language	English
Publishing date	2017-06-12
Publishing country	Italy
Document type	Case Reports ; Journal Article
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
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Article: The EUPEMEN (EUropean PErioperative MEdical Networking) Protocol for Bowel Obstruction: Recommendations for Perioperative Care.

Ioannidis, Orestis / Ramirez, Jose M / Ubieto, Javier Martínez / Feo, Carlo V / Arroyo, Antonio / Kocián, Petr / Sánchez-Guillén, Luis / Bellosta, Ana Pascual / Whitley, Adam / Enguita, Alejandro Bona / Teresa, Marta / Anestiadou, Elissavet

Journal of clinical medicine

2023 Volume 12, Issue 13

Abstract: Mechanical bowel obstruction is a common symptom for admission to emergency services, diagnosed annually in more than 300,000 patients in the States, from whom 51% will undergo emergency laparotomy. This condition is associated with serious morbidity and ...

Abstract	Mechanical bowel obstruction is a common symptom for admission to emergency services, diagnosed annually in more than 300,000 patients in the States, from whom 51% will undergo emergency laparotomy. This condition is associated with serious morbidity and mortality, but it also causes a high financial burden due to long hospital stay. The EUPEMEN project aims to incorporate the expertise and clinical experience of national clinical specialists into development of perioperative rehabilitation protocols. Providing special recommendations for all aspects of patient perioperative care and the participation of diverse specialists, the EUPEMEN protocol for bowel obstruction, as presented in the current paper, aims to provide faster postoperative recovery and reduce length of hospital stay, postoperative morbidity and mortality rate.
Language	English
Publishing date	2023-06-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12134185
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Article ; Online: Laparoscopic versus Open Transverse-Incision Approach for Right Hemicolectomy: A Systematic Review and Meta-Analysis.

Feo, Claudio F / Paliogiannis, Panagiotis / Fancellu, Alessandro / Zinellu, Angelo / Ginesu, Giorgio C / Feo, Carlo V / Porcu, Alberto

Medicina (Kaunas, Lithuania)

2021 Volume 57, Issue 1

MeSH term(s)	Colectomy ; Colonic Neoplasms/surgery ; Humans ; Laparoscopy ; Length of Stay ; Operative Time ; Treatment Outcome
Language	English
Publishing date	2021-01-19
Publishing country	Switzerland
Document type	Journal Article ; Meta-Analysis ; Review ; Systematic Review
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina57010080
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Article ; Online: A rare case of ileo-ileal intussusception due to a bleeding lipomatous mass treated by laparoscopic ileal resection.

Feo, Carlo V / Zese, Monica / Tralli, Giulia / Targa, Simone / Galeotti, Roberto / Rizzati, Roberto

Annali italiani di chirurgia

2019 Volume 8

Abstract: Introduction: Adult intussusception is a rare cause of bowel obstruction with atypical presentation. It can be associated with primary or secondary intestinal tumors and, rarely, with lipomatous masses.: Case report: We report the case of a 69-year ... ...

Abstract	Introduction: Adult intussusception is a rare cause of bowel obstruction with atypical presentation. It can be associated with primary or secondary intestinal tumors and, rarely, with lipomatous masses. Case report: We report the case of a 69-year old man presenting with a history of gastrointestinal bleeding and anemia. Upper and lower endoscopies were negative for bleeding. On abdominal contrast enhanced computerized tomography (CT) scan, a trans-omental hernia in the right lower abdominal quadrant was diagnosed with no active bleeding or evidence of tumor. On exploratory laparoscopy we detected an ileo-ileal intussusception caused by a submucosal mass in the distal ileum, which was reduced and we then performed a segmental resection of the involved small bowel tract. The patient fully recovered by postoperative day 3 when he was discharged home. Final pathology confirmed an ileal lipoma. Conclusion: Ileal intussusception caused by lipoma is a rare condition, which can be diagnosed with endoscopy, barium enema, and abdominal ultrasound or CT scanning, but preoperative diagnosis may be difficult. The treatment of choice is the reduction of the intussusception and the resection (laparoscopic or open) of the involved tract. Key words: Intussusception, Lipoma, Ileum, Laparoscopy, Bleeding.
MeSH term(s)	Aged ; Gastrointestinal Hemorrhage/etiology ; Humans ; Ileal Diseases/etiology ; Ileal Diseases/surgery ; Ileal Neoplasms/complications ; Ileal Neoplasms/surgery ; Intussusception/etiology ; Intussusception/surgery ; Laparoscopy ; Lipoma/complications ; Lipoma/surgery ; Male
Language	English
Publishing date	2019-05-02
Publishing country	Italy
Document type	Case Reports ; Journal Article
ZDB-ID	418927-9
ISSN	2239-253X ; 0003-469X
ISSN (online)	2239-253X
ISSN	0003-469X
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Article ; Online: Minimally invasive myotomy for the treatment of esophageal achalasia: evolution of the surgical procedure and the therapeutic algorithm.

Bresadola, Vittorio / Feo, Carlo V

Surgical laparoscopy, endoscopy & percutaneous techniques

2012 Volume 22, Issue 2, Page(s) 83–87

Abstract: Achalasia is a rare disease of the esophagus, characterized by the absence of peristalsis in the esophageal body and incomplete relaxation of the lower esophageal sphincter, which may be hypertensive. The cause of this disease is unknown; therefore, the ... ...

Abstract	Achalasia is a rare disease of the esophagus, characterized by the absence of peristalsis in the esophageal body and incomplete relaxation of the lower esophageal sphincter, which may be hypertensive. The cause of this disease is unknown; therefore, the aim of the therapy is to improve esophageal emptying by eliminating the outflow resistance caused by the lower esophageal sphincter. This goal can be accomplished either by pneumatic dilatation or surgical myotomy, which are the only long-term effective therapies for achalasia. Historically, pneumatic dilatation was preferred over surgical myotomy because of the morbidity associated with a thoracotomy or a laparotomy. However, with the development of minimally invasive techniques, the surgical approach has gained widespread acceptance among patients and gastroenterologists and, consequently, the role of surgery has changed. The aim of this study was to review the changes occurred in the surgical treatment of achalasia over the last 2 decades; specifically, the development of minimally invasive techniques with the evolution from a thoracoscopic approach without an antireflux procedure to a laparoscopic myotomy with a partial fundoplication, the changes in the length of the myotomy, and the modification of the therapeutic algorithm.
MeSH term(s)	Algorithms ; Esophageal Achalasia/surgery ; Esophageal Sphincter, Lower/surgery ; Esophagectomy/methods ; Esophagectomy/trends ; Gastroesophageal Reflux/surgery ; Humans ; Laparoscopy/methods ; Laparoscopy/trends ; Thoracoscopy/methods ; Thoracoscopy/trends
Language	English
Publishing date	2012-04
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1475108-2
ISSN	1534-4908 ; 1530-4515 ; 1051-7200
ISSN (online)	1534-4908
ISSN	1530-4515 ; 1051-7200
DOI	10.1097/SLE.0b013e318243368f
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