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  1. Article ; Online: Reactivation of

    Feria, Lucia / Torrado, Missia / Anton-Vazquez, Vanesa

    Medicina clinica (English ed.)

    2022  Volume 158, Issue 5, Page(s) 242–243

    Language English
    Publishing date 2022-01-14
    Publishing country Spain
    Document type Journal Article
    ISSN 2387-0206
    ISSN (online) 2387-0206
    DOI 10.1016/j.medcle.2021.05.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reactivación de Strongyloides stercoralis en pacientes con neumonía por SARS-CoV-2 en tratamiento con dexametasona.

    Feria, Lucia / Torrado, Missia / Anton-Vazquez, Vanesa

    Medicina clinica

    2021  Volume 158, Issue 5, Page(s) 242–243

    Title translation Reactivation of Strongyloides stercoralis in patients with SARS-CoV-2 pneumonia receiving dexamethasone.
    MeSH term(s) Animals ; Dexamethasone/adverse effects ; Humans ; Pneumonia ; SARS-CoV-2 ; Strongyloides stercoralis ; Strongyloidiasis/diagnosis ; Strongyloidiasis/drug therapy ; COVID-19 Drug Treatment
    Chemical Substances Dexamethasone (7S5I7G3JQL)
    Language Spanish
    Publishing date 2021-05-27
    Publishing country Spain
    Document type Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2021.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Changing Trends in the Global Consumption of Treatments Used in Hospitalized Patients for COVID-19: A Time Series Multicentre Study.

    Aranda, Judit / Loureiro-Amigo, Jose / Murgadella, Anna / Vàzquez, Núria / Feria, Lucía / Muñoz, Miriam / Padulles, Ariadna / Abelenda, Gabriela / Garcia-Vidal, Carol / Tuset, Montse / Albanell, Marta / Boix-Palop, Lucía / Sanmartí-Martínez, Núria / Gómez-Zorrilla, Sílvia / Echeverria-Esnal, Daniel / Rodriguez-Alarcón, Alicia / Borjabad, Beatriz / Coloma, Ana / Carratalà, Jordi /
    Oriol, Isabel

    Antibiotics (Basel, Switzerland)

    2023  Volume 12, Issue 5

    Abstract: Aim: To analyze trends in the prescription of COVID-19 treatments for hospitalized patients during the pandemic.: Methods: Multicenter, ecological, time-series study of aggregate data for all adult patients with COVID-19 treated in five acute-care ... ...

    Abstract Aim: To analyze trends in the prescription of COVID-19 treatments for hospitalized patients during the pandemic.
    Methods: Multicenter, ecological, time-series study of aggregate data for all adult patients with COVID-19 treated in five acute-care hospitals in Barcelona, Spain, between March 2020 and May 2021. Trends in the monthly prevalence of drugs used against COVID-19 were analyzed by the Mantel-Haenszel test.
    Results: The participating hospitals admitted 22,277 patients with COVID-19 during the study period, reporting an overall mortality of 10.8%. In the first months of the pandemic, lopinavir/ritonavir and hydroxychloroquine were the most frequently used antivirals, but these fell into disuse and were replaced by remdesivir in July 2020. By contrast, the trend in tocilizumab use varied, first peaking in April and May 2020, declining until January 2021, and showing a discrete upward trend thereafter. Regarding corticosteroid use, we observed a notable upward trend in the use of dexamethasone 6 mg per day from July 2020. Finally, there was a high prevalence of antibiotics use, especially azithromycin, in the first three months, but this decreased thereafter.
    Conclusions: Treatment for patients hospitalized with COVID-19 evolved with the changing scientific evidence during the pandemic. Initially, multiple drugs were empirically used that subsequently could not demonstrate clinical benefit. In future pandemics, stakeholders should strive to promote the early implementation of adaptive randomized clinical trials.
    Language English
    Publishing date 2023-04-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics12050809
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  4. Article ; Online: Persistent COVID-19 symptoms 1 year after hospital discharge: A prospective multicenter study.

    Aranda, Judit / Oriol, Isabel / Feria, Lucía / Abelenda, Gabriela / Rombauts, Alexander / Simonetti, Antonella Francesca / Catalano, Clarisa / Pallarès, Natàlia / Martín, Miguel / Vàzquez, Núria / Vall-Llosera, Estel / Rhyman, Nicolás / Suárez, Romina Concepción / Nogué, Marta / Loureiro-Amigo, Jose / Coloma, Ana / Ceresuela, Luis / Carratalà, Jordi

    PloS one

    2022  Volume 17, Issue 10, Page(s) e0275615

    Abstract: Objective: To determine the health status and exercise capacity of COVID-19 survivors one year after hospital discharge.: Methods: This multicenter prospective study included COVID-19 survivors 12 months after hospital discharge. Participants were ... ...

    Abstract Objective: To determine the health status and exercise capacity of COVID-19 survivors one year after hospital discharge.
    Methods: This multicenter prospective study included COVID-19 survivors 12 months after hospital discharge. Participants were randomly selected from a large cohort of COVID-19 patients who had been hospitalized until 15th April 2020. They were interviewed about persistent symptoms, underwent a physical examination, chest X-ray, and a 6-minute walk test (6MWT). A multivariate analysis was performed to determine the risk factors for persistent dyspnea.
    Results: Of the 150 patients included, 58% were male and the median age was 63 (IQR 54-72) years. About 82% reported ≥1 symptoms and 45% had not recovered their physical health. The multivariate regression analysis revealed that the female sex, chronic obstructive pulmonary disease, and smoking were independent risk factors for persistent dyspnea. Approximately 50% completed less than 80% of the theoretical distance on the 6MWT. Only 14% had an abnormal X-ray, showing mainly interstitial infiltrates. A third of them had been followed up in outpatient clinics and 6% had undergone physical rehabilitation.
    Conclusion: Despite the high rate of survivors of the first wave of the COVID-19 pandemic with persistent symptomatology at 12 months, the follow-up and rehabilitation of these patients has been really poor. Studies focusing on the role of smoking in the persistence of COVID-19 symptoms are lacking.
    MeSH term(s) COVID-19/epidemiology ; Dyspnea/epidemiology ; Dyspnea/etiology ; Female ; Hospitals ; Humans ; Male ; Middle Aged ; Pandemics ; Patient Discharge ; Prospective Studies
    Language English
    Publishing date 2022-10-10
    Publishing country United States
    Document type Journal Article ; Multicenter Study
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0275615
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  5. Article ; Online: Long-term impact of COVID-19 associated acute respiratory distress syndrome.

    Aranda, Judit / Oriol, Isabel / Martín, Miguel / Feria, Lucía / Vázquez, Núria / Rhyman, Nicolás / Vall-Llosera, Estel / Pallarés, Natàlia / Coloma, Ana / Pestaña, Melani / Loureiro, Jose / Güell, Elena / Borjabad, Beatriz / León, Elena / Franz, Elena / Domènech, Anna / Pintado, Sara / Contra, Anna / Cortés, María Del Señor /
    Chivite, Iván / Clivillé, Raquel / Vacas, Montserrat / Ceresuela, Luis Miguel / Carratalà, Jordi

    The Journal of infection

    2021  Volume 83, Issue 5, Page(s) 581–588

    Abstract: Objectives: To determine the health status, exercise capacity, and health related quality of life (HRQoL) of COVID-19 associated acute respiratory distress syndrome (ARDS) survivors, 8 months after diagnosis.: Methods: All eligible patients were ... ...

    Abstract Objectives: To determine the health status, exercise capacity, and health related quality of life (HRQoL) of COVID-19 associated acute respiratory distress syndrome (ARDS) survivors, 8 months after diagnosis.
    Methods: All eligible patients were interviewed and underwent a physical examination, chest X-ray, and 6 min walk test (6MWT). Scales to evaluate post-traumatic stress disorder, depression, anxiety, and HRQoL were applied.
    Results: Of 1295 patients, 365 suffered ARDS and 166 survived to hospital discharge. Five died after discharge and 48 were lost to follow-up. Of the 113 remaining patients, 81% had persistent symptoms. More than 50% of patients completed less than 80% of the theoretical distance on the 6MWT, 50% had an abnormal X-ray and 93% of patients developed psychiatric disorders. Mean SF-36 scores were worse than in the general population. After multivariate regression analysis, female sex, non-Caucasian race, and Charlson index>2 were independent risk factors for a worse mental health component summary score on the SF-36, and age was associated with a better prognosis. Female sex and chronic obstructive pulmonary disease were independently associated with a worse physical component summary score.
    Conclusion: COVID-19 associated ARDS survivors have long-term consequences in health status, exercise capacity, and HRQoL. Strategies addressed to prevent these sequelae are needed.
    MeSH term(s) COVID-19 ; Female ; Humans ; Quality of Life ; Respiratory Distress Syndrome/epidemiology ; SARS-CoV-2 ; Survivors
    Language English
    Publishing date 2021-08-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2021.08.018
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