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  1. AU="Fernández-López, Antonio R"
  2. AU="Urbán, Dániel"
  3. AU="Noor, Norhayati Mohd"
  4. AU="Blake, Kerrigan"
  5. AU="Oikawa, Shoko"
  6. AU="Ebert, Martin"
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  1. Artikel ; Online: Evaluation of health outcomes after the implementation of rotational thromboelastometry in patients undergoing cardiac surgery.

    Rodríguez-Martín, Isabel / Sánchez-Mora, Catalina / Fernández-López, Antonio R / González-Fernández, Francisco J / Téllez-Cantero, Juan Carlos / Blanco-Marquez, Verónica / García de la Borbolla, Mariano / Santos-Jiménez, Juan C / González-Rodríguez, Concepción / Garnacho-Montero, José / Sánchez-Margalet, Víctor

    Scandinavian journal of clinical and laboratory investigation

    2022  Band 82, Heft 2, Seite(n) 143–149

    Abstract: Background: Viscoelastic tests (rotational thromboelastometry, ROTEM: Methods: Retrospective cohort study including 675 patients who underwent cardiac surgery with cardiopulmonary bypass. The incidence of allogeneic blood transfusions and clinical ... ...

    Abstract Background: Viscoelastic tests (rotational thromboelastometry, ROTEM
    Methods: Retrospective cohort study including 675 patients who underwent cardiac surgery with cardiopulmonary bypass. The incidence of allogeneic blood transfusions and clinical postoperative complications were analyzed before and after ROTEM
    Results: Following viscoelastic testing and the implementation of a specific algorithm for coagulation management, the incidence of any allogeneic blood transfusion decreased (41.4% vs 31.9%,
    Conclusions: The monitoring of hemostasis by ROTEM
    Mesh-Begriff(e) Cardiac Surgical Procedures/adverse effects ; Humans ; Outcome Assessment, Health Care ; Postoperative Hemorrhage/prevention & control ; Retrospective Studies ; Thrombelastography/methods
    Sprache Englisch
    Erscheinungsdatum 2022-02-03
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 3150-1
    ISSN 1502-7686 ; 0036-5513
    ISSN (online) 1502-7686
    ISSN 0036-5513
    DOI 10.1080/00365513.2022.2034038
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Postoperative costs associated with outcomes after cardiac surgery with extracorporeal circulation: role of antithrombin levels.

    Muedra, Vicente / Llau, Juan V / Llagunes, José / Paniagua, Pilar / Veiras, Sonia / Fernández-López, Antonio R / Diago, Carmen / Hidalgo, Francisco / Gil, Jesús / Valiño, Cristina / Moret, Enric / Gómez, Laura / Pajares, Azucena / de Prada, Blanca

    Journal of cardiothoracic and vascular anesthesia

    2013  Band 27, Heft 2, Seite(n) 230–237

    Abstract: Objective: To study the impact on postoperative costs of a patient's antithrombin levels associated with outcomes after cardiac surgery with extracorporeal circulation.: Design: An analytic decision model was designed to estimate costs and clinical ... ...

    Abstract Objective: To study the impact on postoperative costs of a patient's antithrombin levels associated with outcomes after cardiac surgery with extracorporeal circulation.
    Design: An analytic decision model was designed to estimate costs and clinical outcomes after cardiac surgery in a typical patient with low antithrombin levels (<63.7%) compared with a patient with normal antithrombin levels (≥63.7%). The data used in the model were obtained from a literature review and subsequently validated by a panel of experts in cardiothoracic anesthesiology.
    Setting: Multi-institutional (14 Spanish hospitals).
    Participants: Consultant anesthesiologists.
    Measurements and main results: A sensitivity analysis of extreme scenarios was carried out to assess the impact of the major variables in the model results. The average cost per patient was €18,772 for a typical patient with low antithrombin levels and €13,881 for a typical patient with normal antithrombin levels. The difference in cost was due mainly to the longer hospital stay of a patient with low antithrombin levels compared with a patient with normal levels (13 v 10 days, respectively, representing a €4,596 higher cost) rather than to costs related to the management of postoperative complications (€215, mostly owing to transfusions). Sensitivity analysis showed a high variability range of approximately ±55% of the base case cost between the minimum and maximum scenarios, with the hospital stay contributing more significantly to the variation.
    Conclusions: Based on this analytic decision model, there could be a marked increase in the postoperative costs of patients with low antithrombin activity levels at the end of cardiac surgery, mainly ascribed to a longer hospitalization.
    Mesh-Begriff(e) Aged ; Antithrombins/blood ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/economics ; Atrial Fibrillation/etiology ; Blood Transfusion/economics ; Cardiac Surgical Procedures/adverse effects ; Cardiac Surgical Procedures/economics ; Cardiotonic Agents/economics ; Cardiotonic Agents/therapeutic use ; Costs and Cost Analysis ; Decision Trees ; Drug Costs ; Drug Therapy/economics ; Extracorporeal Circulation/adverse effects ; Extracorporeal Circulation/economics ; Female ; Health Care Surveys ; Humans ; Intensive Care Units/economics ; Kidney Diseases/diagnosis ; Kidney Diseases/economics ; Kidney Diseases/etiology ; Length of Stay ; Male ; Middle Aged ; Myocardial Infarction/diagnosis ; Myocardial Infarction/economics ; Myocardial Infarction/etiology ; Postoperative Care/economics ; Postoperative Complications/blood ; Postoperative Complications/economics ; Postoperative Complications/epidemiology ; Spain/epidemiology ; Stroke/economics ; Stroke/etiology ; Surveys and Questionnaires ; Thromboembolism/diagnosis ; Thromboembolism/economics ; Thromboembolism/etiology ; Treatment Outcome
    Chemische Substanzen Antithrombins ; Cardiotonic Agents
    Sprache Englisch
    Erscheinungsdatum 2013-04
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1067317-9
    ISSN 1532-8422 ; 1053-0770
    ISSN (online) 1532-8422
    ISSN 1053-0770
    DOI 10.1053/j.jvca.2012.08.017
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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