Article ; Online: Pseudomonas aeruginosa
The Lancet regional health. Europe
2023 Volume 34, Page(s) 100736
Abstract: Background: Pseudomonas aeruginosa: Methods: A total of 3.180 nonduplicated : Findings: A decrease in resistance to all tested antibiotics, including older and newer antimicrobials, was observed in 2022 vs 2017. Likewise, a major reduction of XDR ( ...
| Abstract | Background: Pseudomonas aeruginosa Methods: A total of 3.180 nonduplicated Findings: A decrease in resistance to all tested antibiotics, including older and newer antimicrobials, was observed in 2022 vs 2017. Likewise, a major reduction of XDR (15.2% vs 5.9%) and DTR (4.2 vs 2.1%) profiles was evidenced, and even more patent among ICU isolates [XDR (26.0% vs 6.0%) and DTR (8.9% vs 2.6%)] (p < 0.001). The prevalence of Extended-spectrum β-lactamase/carbapenemase production was slightly lower in 2022 (2.1%. vs 3.1%, p = 0.064). However, there was a significant increase in the proportion of carbapenemase production among carbapenem-resistant strains (29.4% vs 18.1%, p = 0.0246). While ST175 was still the most frequent clone among XDR, a slight reduction in its prevalence was noted (35.9% vs 45.5%, p = 0.106) as opposed to ST235 which increased significantly (24.3% vs 12.3%, p = 0.0062). Interpretation: While the generalized decrease in Funding: MSD and the Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación and Unión Europea-NextGenerationEU. |
|---|---|
| Language | English |
| Publishing date | 2023-09-19 |
| Publishing country | England |
| Document type | Journal Article |
| ISSN | 2666-7762 |
| ISSN (online) | 2666-7762 |
| DOI | 10.1016/j.lanepe.2023.100736 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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