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  1. Article: Monitoring thyroid function during amiodarone use.

    Sharma, Priya / Sheikh, Riyad / Siribaddana, Nipuna / Sathyanarayanan, Abilash / Fernando, Devaka / Muraleedharan, Vakkat

    British journal of hospital medicine (London, England : 2005)

    2024  Volume 85, Issue 1, Page(s) 1–5

    Abstract: Amiodarone is an antiarrhythmic drug used to treat cardiac tachyarrhythmias. It has many adverse effects, with thyroid dysfunction one of the most notable. Through various mechanisms, both thyrotoxicosis and hypothyroidism can occur secondary to ... ...

    Abstract Amiodarone is an antiarrhythmic drug used to treat cardiac tachyarrhythmias. It has many adverse effects, with thyroid dysfunction one of the most notable. Through various mechanisms, both thyrotoxicosis and hypothyroidism can occur secondary to amiodarone therapy. There are two types of amiodarone-induced thyrotoxicosis: type 1 occurs in those with pre-existing thyroid disease and is treated with thionamide, whereas type 2 occurs in those without and is treated with glucocorticoids. Patients with amiodarone-induced hypothyroidism may be given levothyroxine to replace thyroid hormone, but in some cases, the appropriate management may be cessation of amiodarone.
    MeSH term(s) Humans ; Amiodarone/adverse effects ; Anti-Arrhythmia Agents/adverse effects ; Hypothyroidism/chemically induced ; Hypothyroidism/drug therapy ; Thyrotoxicosis/chemically induced ; Thyrotoxicosis/drug therapy
    Chemical Substances Amiodarone (N3RQ532IUT) ; Anti-Arrhythmia Agents
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Journal Article
    ISSN 1750-8460
    ISSN 1750-8460
    DOI 10.12968/hmed.2023.0214
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Tumour-induced osteomalacia.

    Nuam, Cing San / Tun, Thein Zaw / Fernando, Devaka

    Clinical medicine (London, England)

    2022  Volume 22, Issue Suppl 4, Page(s) 24

    MeSH term(s) Humans ; Osteomalacia/etiology ; Paraneoplastic Syndromes/diagnosis ; Paraneoplastic Syndromes/etiology
    Language English
    Publishing date 2022-10-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.22-4-s24
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5439: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Amlodipine induced hyponatraemia.

    Tun, Thein Zaw / Nuam, Cing San / Fernando, Devaka

    Clinical medicine (London, England)

    2022  Volume 22, Issue Suppl 4, Page(s) 41

    MeSH term(s) Amlodipine/adverse effects ; Humans ; Hyponatremia/chemically induced ; Risk Factors
    Chemical Substances Amlodipine (1J444QC288)
    Language English
    Publishing date 2022-10-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2048646-7
    ISSN 1473-4893 ; 1470-2118
    ISSN (online) 1473-4893
    ISSN 1470-2118
    DOI 10.7861/clinmed.22-4-s41
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5439: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: The Effect of Salacia Reticulata Extract Biscuits on Blood Sugar Control of Type 2 Diabetes Mellitus Patients: A Two-Period, Two-Sequence, Crossover, Randomized, Triple-Blind, Placebo-Controlled, Clinical Trial.

    Siribaddana, Sisira / Medagama, Arjuna / Wickramasinghe, Nadeesha / Siribaddana, Nipuna M / Agampodi, Suneth / Fernando, Devaka

    Cureus

    2023  Volume 15, Issue 9, Page(s) e45921

    Abstract: Background Traditional physicians in Sri Lanka and India use extracts from the ... ...

    Abstract Background Traditional physicians in Sri Lanka and India use extracts from the plant
    Language English
    Publishing date 2023-09-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.45921
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  5. Article: Non-training clinical fellowships.

    Fernando, Devaka / Dharmarajan, Venoden / Smith, Daniel / Cox, Giles / Noor, Muhammed / Haynes, Andrew

    Future healthcare journal

    2019  Volume 6, Issue 2, Page(s) 147–148

    Language English
    Publishing date 2019-07-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 3016427-8
    ISSN 2514-6653 ; 2514-6645
    ISSN (online) 2514-6653
    ISSN 2514-6645
    DOI 10.7861/futurehosp.6-2-147a
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  6. Article ; Online: Energy and nutrient intakes of Sri Lankan patients with type 2 diabetes mellitus: a cross-sectional survey.

    Medagama, Arjuna / Fernando, Devaka / Widanapathirana, Heshan

    BMC research notes

    2015  Volume 8, Page(s) 753

    Abstract: Background: Sri Lanka has a high prevalence of type 2 diabetes mellitus. Energy and macronutrient intakes of diabetic patients have not been previously studied in this population. We aimed to clarify the energy and nutrient intakes among a group of type ...

    Abstract Background: Sri Lanka has a high prevalence of type 2 diabetes mellitus. Energy and macronutrient intakes of diabetic patients have not been previously studied in this population. We aimed to clarify the energy and nutrient intakes among a group of type 2 diabetic patients attending a tertiary care diabetes facility in Sri Lanka.
    Methods: Nutritional and energy intake of 123 randomly selected patients with type 2 diabetes, aged 30-74 years was assessed using a 24-h dietary recall.
    Results: The mean energy intake for all participants was 1438 (SD 412) Kcal/day. The mean proportions of total carbohydrate, protein and fat comprising total energy intake were 68.1, 11.5 and 20.2 % respectively. The mean carbohydrate intake of 249.7 g/day comprised 50 % of rice. The mean daily protein, fat and dietary fibre intake was 42.5, 33 and 18.1 g respectively with a major contribution from plant sources. There was no significant difference in energy and nutrient intakes among the male and female participants.
    Conclusion: The present study provides the first pilot data on the energy and macronutrient intakes of diabetes patients in Sri Lanka. We clarified that these patients consumed an energy restricted, high-carbohydrate low fat diet compared to western diabetic patients. A larger nationwide dietary survey is recommended to confirm our findings.
    MeSH term(s) Adult ; Aged ; Cross-Sectional Studies ; Diabetes Mellitus, Type 2 ; Eating ; Energy Intake ; Female ; Humans ; Male ; Middle Aged ; Pilot Projects ; Sri Lanka
    Language English
    Publishing date 2015-12-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2413336-X
    ISSN 1756-0500 ; 1756-0500
    ISSN (online) 1756-0500
    ISSN 1756-0500
    DOI 10.1186/s13104-015-1732-5
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  7. Article: Rising HbA1c in the presence of optimal glycaemic control as assessed by self-monitoring - iron deficiency anaemia.

    Mudenha, Emily T / Aarella, Vikram G / Chandrasekaram, Senthil / Fernando, Devaka Js

    JRSM open

    2016  Volume 7, Issue 2, Page(s) 2054270415619321

    Abstract: HbA1c can be affected by determinants other than glucose and an awareness of this is important to avoid unnecessary hypoglycaemia. ...

    Abstract HbA1c can be affected by determinants other than glucose and an awareness of this is important to avoid unnecessary hypoglycaemia.
    Language English
    Publishing date 2016-01-18
    Publishing country England
    Document type Case Reports
    ZDB-ID 2762955-7
    ISSN 2054-2704
    ISSN 2054-2704
    DOI 10.1177/2054270415619321
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  8. Article ; Online: Acute Transient Stress Induced Adrenal Hypertrophy and Adrenal Medullary Hyperactivity.

    Aarella, Vikram G / Mudenha, Emily T / Okpe, Andrew / Fernando, Devaka Js

    European journal of case reports in internal medicine

    2015  Volume 3, Issue 1, Page(s) 257

    Abstract: Objectives: A: Material and methods: An acute presentation of adrenal gland hypertrophy following an abdominal emergency, with subsequent hypoadrenalism was investigated.: Results: Adrenal medullary and cortical function fully recovered without ... ...

    Abstract Objectives: A
    Material and methods: An acute presentation of adrenal gland hypertrophy following an abdominal emergency, with subsequent hypoadrenalism was investigated.
    Results: Adrenal medullary and cortical function fully recovered without treatment.
    Conclusions: We postulate that the adrenal glands became enlarged and hypertrophied during an acute stress event, possibly caused by acute adrenal medullary hypersecretion and subsequent cortical hyposecretion. A wait and watch policy should be followed if no other clinical symptoms and signs of adrenal disease are present. CT scan remains an important diagnostic tool.
    Learning points: Abnormal adrenocortical function tests and hypertrophy can occur in an acutely ill patient as a stress response.It is possible to have both hypersecretion and hyposecretion of adrenal hormones.A wait and watch policy should be followed if no other clinical symptoms and signs of adrenal disease are present in an acutely ill patient.
    Language English
    Publishing date 2015-11-17
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2015_000257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dysautonomia: an Explanation for the Medically Unexplained?

    Chandrasekaram, Senthil / Fernando, Ranga H / Aarella, Vikram / Mudenha, Emily T / Fernando, Devaka Js

    European journal of case reports in internal medicine

    2016  Volume 3, Issue 5, Page(s) 430

    Abstract: Objective: To identify dysautonomia as a collection of conditions with variable presentation that may be mistaken for medically unexplained symptoms.: Methods: Case series.: Results: Tilt table testing and 24 h electrocardiographic monitoring ... ...

    Abstract Objective: To identify dysautonomia as a collection of conditions with variable presentation that may be mistaken for medically unexplained symptoms.
    Methods: Case series.
    Results: Tilt table testing and 24 h electrocardiographic monitoring provided useful diagnostic tools to confirm the diagnosis.
    Conclusion: A greater awareness and recognition of the disorders that result from dysautonomia and recognition of the disability that results from these disorders will improve patients' quality of life.
    Learning points: Dysautonomia is protean in presentation and clinicians need to have a high degree of suspicion as, if diagnosed, symptomatic improvement is possible leading to improved quality of life.Tilt table testing and 24 h electrocardiographic monitoring are useful diagnostic tools.Greater awareness and recognition of the disorders that result from dysautonomia with appropriate use of these tests by medical professionals is necessary.
    Language English
    Publishing date 2016-06-01
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2016_000430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Hypoglyceamia in a Patient with a Solitary Fibrous Tumour.

    Okpe, Andrew / Ramsay, Kerri / Fernando, Isuru P / Mudenha, Emily / Fernando, Devaka Js

    European journal of case reports in internal medicine

    2016  Volume 3, Issue 3, Page(s) 353

    Abstract: Objective: To illustrate an unusual mechanism causing hypoglycaemia.: Material and methods: A 76-year-old man presented with episodes of agitation and confusion and was resuscitated with oral glucose gel when found to be hypoglycaemic.: Results: A ...

    Abstract Objective: To illustrate an unusual mechanism causing hypoglycaemia.
    Material and methods: A 76-year-old man presented with episodes of agitation and confusion and was resuscitated with oral glucose gel when found to be hypoglycaemic.
    Results: A CT scan for an abdominal mass confirmed a solitary fibrous tumour (SFT). The sarcoma multidisciplinary team suggested conservative management. The patient's episodic hypoglycaemia was managed with diet modification including corn-based starch, scheduled snacks and dexamethasone. Glucose levels were within normal range at discharge from hospital. The patient was referred to the palliative care team for follow-up.
    Conclusion: SFTs causing non-islet cell tumour hypoglycaemia are difficult to treat.
    Learning points: To be aware of rarer causes of hypoglycaemia and to consider unusual causes in acute presentations of hypoglycaemia, especially in patients who do not have diabetes.This case illustrates the importance of a thorough general physical and systemic examination, as identifying the abdominal mass is essential to the early diagnosis of this rare condition.Solitary fibrous tumours causing non-islet cell tumour hypoglycaemia are difficult to treat, and even when surgical resections are applicable, recurrence rates are high.
    Language English
    Publishing date 2016-03-07
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2016_000353
    Database MEDical Literature Analysis and Retrieval System OnLINE

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