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  1. Article ; Online: Inequidades sociales en madres adolescentes y la relación con resultados perinatales adversos en poblaciones sudamericanas

    Julia Ratowiecki / María Rita Santos / Fernando Poletta / Silvina Heisecke / Dario Elias / Juan Gili / Lucas Gimenez / Mariela Pawluk / Rocio Uranga / Viviana Cosentino / Hebe Campaña / Mónica Rittler / Jorge S. López Camelo

    Cadernos de Saúde Pública, Vol 36, Iss

    2021  Volume 12

    Abstract: Resumen: El objetivo fue explicar las diferencias en la frecuencia de eventos perinatales adversos entre madres adolescentes con baja y alta escolaridad. La muestra poblacional se recogió en la base de datos del Estudio Colaborativo Latinoamericano de ... ...

    Abstract Resumen: El objetivo fue explicar las diferencias en la frecuencia de eventos perinatales adversos entre madres adolescentes con baja y alta escolaridad. La muestra poblacional se recogió en la base de datos del Estudio Colaborativo Latinoamericano de Malformaciones Congénitas (ECLAMC). Entre 2.443.747 nacimientos ocurridos en 93 hospitales, se reclutaron 66.755 recién nacidos vivos, sin defectos congénitos, durante el período 2000-2017. Las madres adolescentes se clasificaron según su escolaridad en: baja, media y alta. Se utilizó un modelo multivariado, que incluyó efectos reproductivos, acceso a servicios de salud, variables demográficas-socioeconómicas, así como de grupo étnico. El modelo de descomposición de Fairlie se aplicó para cuantificar la contribución de variables explicativas en las frecuencias de eventos perinatales adversos. De los 66.755 recién nacidos investigados, el 21,1% (n = 14.078) fue primigrávida de madres adolescentes. La distribución por escolaridad materna fue de 24,2%, 59,8% y 16% para baja, media y alta escolaridad, respectivamente. Las mayores frecuencias de eventos perinatales adversos se observaron en madres adolescentes con baja escolaridad. La variable “acceso a servicios de salud” explicó un 35%, 37% y 23% de las disparidades en el bajo peso al nacimiento, prematuridad y retardo de crecimiento intrauterino, respectivamente, entre madres adolescentes con baja y alta escolaridad. El bajo número de consultas prenatales fue el único factor de riesgo para los dos niveles de escolaridad y la variable que mejor explica las diferencias entre las frecuencias de eventos perinatales adversos. Desde el punto de vista de la salud pública, ellos representan una intervención de bajo coste, con posibilidad de que se incrementen mediante información adecuada para la población y medidas sistemáticas en los niveles de atención primaria.
    Keywords Nacimiento Prematuro ; Peso al Nacer ; Embarazo en Adolescencia ; Escolaridad ; Inequidad Social ; Medicine ; R ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: A graph theory approach to analyze birth defect associations.

    Dario Elias / Hebe Campaña / Fernando Poletta / Silvina Heisecke / Juan Gili / Julia Ratowiecki / Lucas Gimenez / Mariela Pawluk / Maria Rita Santos / Viviana Cosentino / Rocio Uranga / Monica Rittler / Jorge Lopez Camelo

    PLoS ONE, Vol 15, Iss 5, p e

    2020  Volume 0233529

    Abstract: Birth defects are prenatal morphological or functional anomalies. Associations among them are studied to identify their etiopathogenesis. The graph theory methods allow analyzing relationships among a complete set of anomalies. A graph consists of nodes ... ...

    Abstract Birth defects are prenatal morphological or functional anomalies. Associations among them are studied to identify their etiopathogenesis. The graph theory methods allow analyzing relationships among a complete set of anomalies. A graph consists of nodes which represent the entities (birth defects in the present work), and edges that join nodes indicating the relationships among them. The aim of the present study was to validate the graph theory methods to study birth defect associations. All birth defects monitoring records from the Estudio Colaborativo Latino Americano de Malformaciones Congénitas gathered between 1967 and 2017 were used. From around 5 million live and stillborn infants, 170,430 had one or more birth defects. Volume-adjusted Chi-Square was used to determine the association strength between two birth defects and to weight the graph edges. The complete birth defect graph showed a Log-Normal degree distribution and its characteristics differed from random, scale-free and small-world graphs. The graph comprised 118 nodes and 550 edges. Birth defects with the highest centrality values were nonspecific codes such as Other upper limb anomalies. After partition, the graph yielded 12 groups; most of them were recognizable and included conditions such as VATER and OEIS associations, and Patau syndrome. Our findings validate the graph theory methods to study birth defect associations. This method may contribute to identify underlying etiopathogeneses as well as to improve coding systems.
    Keywords Medicine ; R ; Science ; Q
    Subject code 511
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Hemoglobin concentration variations over time in general medical inpatients.

    Languasco, Agustin / Agustin, Languasco / Cazap, Nicolas / Nicolas, Cazap / Marciano, Sebastian / Sebastian, Marciano / Huber, Marina / Marina, Huber / Novillo, Abel / Abel, Novillo / Poletta, Fernando / Fernando, Poletta / Milberg, Matias / Matias, Milberg / Riveros, Dardo / Dardo, Riveros

    Journal of hospital medicine

    2010  Volume 5, Issue 5, Page(s) 283–288

    Abstract: Background: A decrease in hemoglobin concentration [Hb] with no apparent cause is frequently observed in critically ill patients. Scarce information is available about this situation in general ward-admitted patients (GWAP).: Objectives: To describe [ ...

    Abstract Background: A decrease in hemoglobin concentration [Hb] with no apparent cause is frequently observed in critically ill patients. Scarce information is available about this situation in general ward-admitted patients (GWAP).
    Objectives: To describe [Hb] variation with no obvious cause in GWAP, and to estimate the prevalence and predictors of patients with [Hb] decreases > or =1.5 g/dL.
    Design, setting and patients: Prospective, observational study in internal medicine GWAP, carried out at two teaching hospitals in Buenos Aires, Argentina. Patients with a history of, or admitted for diseases associated with decreases in [Hb], as well as those with length of stay less than three days, were excluded.
    Measurements: Upon hospitalization, complete personal and clinical data were recorded. Furthermore, Katz index, APACHE II acute physiology score (APS) and Charlson score were calculated. [Hb] and hematocrit (HCT) were also assessed during hospitalization.
    Results: A total of 338 patients were evaluated, 131 were included. A mean [Hb] decrease of 0.71 g/dL was observed between admission and discharge (P < 0.001; 95% CI, 0.47-0.97). Forty-five percent of the included patients had decreases in [Hb] > or = 1.5 g/dL. This was associated with a higher APS, a higher [Hb] at admission, and a discharge diagnosis of infectious or gastrointestinal disease. No bleeding episodes were observed.
    Conclusions: An [Hb] decrease was frequently observed during GWAP hospitalization with no evident blood loss. Even though this decrease has multiple causes, the severity of the acute illness seems to play a major role.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Critical Illness/epidemiology ; Erythrocyte Count/trends ; Erythrocyte Indices/physiology ; Female ; Hemoglobins/metabolism ; Hospitalization/trends ; Hospitals, Teaching/trends ; Humans ; Internal Medicine/trends ; Male ; Middle Aged ; Prospective Studies ; Severity of Illness Index ; Time Factors ; Young Adult
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2010-05
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Multicenter Study
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.1002/jhm.650
    Database MEDical Literature Analysis and Retrieval System OnLINE

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