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Article ; Online: Biphasic Kinetics of IGF-I and IGFBP-3 in Response to Military Field Training in Brazilian Air Force Recruits.

Talarico Neto, Thomaz / Magraner, José Maurício / Hahns Júnior, Higino Carlos / Ferreira, Leandro / Martinelli Júnior, Carlos Eduardo / Tourinho Filho, Hugo

Military medicine

2024

Abstract: Introduction: Insulin-like growth factor type I (IGF-I) has gained considerable notoriety in military training, primarily because it is responsible for energy deficits and sensitive to an inadequate protein intake, which are situations that are commonly ...

Abstract	Introduction: Insulin-like growth factor type I (IGF-I) has gained considerable notoriety in military training, primarily because it is responsible for energy deficits and sensitive to an inadequate protein intake, which are situations that are commonly experienced in specific military operations. Therefore, this study aimed to assess the kinetics of IGF-I and insulin-like growth factor binding protein type 3 (IGFBP-3) in a 4-day military field training exercise. Materials and methods: The sample comprised 12 male soldiers (21.71 ± 1.64 years). Changes were assessed at 3 times: time 1-basal (control week); time 2-after specific military field training; and time 3-1 week after the specific training (control week). Changes in body composition and serum levels of IGF-I and IGFBP-3 were observed. Results: The main finding of this study was it verified the biphasic kinetics of both IGF-I and IGFBP-3 at the 3 times observed, that is, a significant drop from time 1 (basal-IGF-I: 189 ng/mL and IGFBP-3: 4.71 mg/L) to time 2 (immediately after military training-IGF-I: 162 ng/mL and IGFBP-3: 4.08 mg/L) and a subsequent recovery of these markers, with a significant increase from time 2 (immediately after military training) to time 3 (a week after military training-IGF-I: 199 ng/mL and IGFBP-3: 4.96 mg/L). Conclusions: It can be concluded that IGF-I and IGFBP-3 levels respond quickly to the stimuli caused by military training, especially after specific field training. However, the same markers quickly return to their basal values after this type of training finishes, simply by following the daily routine of the battalion in the control weeks, with no specific intervention being necessary.
Language	English
Publishing date	2024-04-30
Publishing country	England
Document type	Journal Article
ZDB-ID	391061-1
ISSN	1930-613X ; 0026-4075
ISSN (online)	1930-613X
ISSN	0026-4075
DOI	10.1093/milmed/usae097
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Article ; Online: Postoperative Resting Metabolic Rate and Successful Weight Loss After Roux-en-Y Gastric Bypass.

Cardia, Lilian / de Cleva, Roberto / Ferreira, Leandro / Gadducci, Alexandre Vieira / Estabile, Priscila / Santos Silva, Paulo Roberto / Greve, Julia / Santo, Marco Aurelio

Obesity surgery

2023 Volume 33, Issue 4, Page(s) 1178–1183

Abstract: Objective: To analyze whether changes in RMR 6 months after RYGB could be a predictor of weight loss on late follow-up.: Methods: Prospective study of 45 individuals submitted to RYGB in a university tertiary care hospital. Body composition was ... ...

Abstract	Objective: To analyze whether changes in RMR 6 months after RYGB could be a predictor of weight loss on late follow-up. Methods: Prospective study of 45 individuals submitted to RYGB in a university tertiary care hospital. Body composition was evaluated by bioelectrical impedance analysis and RMR by indirect calorimetry before (T0), 6 (T1), and 36 months (T2) after surgery. Results: RMR/day was lower in T1 (1.552 ± 275 kcal/day) than in T0 (1734 ± 372 kcal/day; p < 0.001) with a return to similar values at T2 (1.795 ± 396 kcal/day; p < 0.001). In T0, there was no correlation between RMR/kg and body composition. In T1, there was a negative correlation between RMR and BW, BMI, and % FM, and a positive correlation with % FFM. The results in T2 were similar to T1. There was a significant increase in RMR/kg between T0, T1, and T2 (13.6 ± 2.2 kcal/kg, 16.9 ± 2.7 kcal/kg, and 19.9 ± 3.4 kcal/kg) in the total group and according to gender. Eighty percent of the patients who had increased RMR/kg ≥ 2 kcal at T1 achieved > 50% EWL in T2, particularly in women (odds ratio: 27.09, p < 0.037). Conclusions: The increase in RMR/kg after RYGB is a major factor related to a satisfactory % excess weight loss on late follow-up.
MeSH term(s)	Humans ; Female ; Gastric Bypass/methods ; Basal Metabolism ; Obesity, Morbid/surgery ; Prospective Studies ; Energy Metabolism ; Body Composition ; Weight Loss ; Body Mass Index
Language	English
Publishing date	2023-02-18
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-023-06498-2
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Article ; Online: Induced drought strongly affects richness and composition of ground-dwelling ants in the eastern Amazon.

Almeida, Rony P S / Silva, Rogério R / da Costa, Antonio C Lôla / Ferreira, Leandro V / Meir, Patrick / Ellison, Aaron M

Oecologia

2023 Volume 201, Issue 2, Page(s) 299–309

Abstract: Species loss in tropical regions is forecast to occur under environmental change scenarios of low precipitation. One of the main questions is how drought will affect invertebrates, a key group for ecosystem functioning. We use 1 year of data from a long- ... ...

Abstract	Species loss in tropical regions is forecast to occur under environmental change scenarios of low precipitation. One of the main questions is how drought will affect invertebrates, a key group for ecosystem functioning. We use 1 year of data from a long-term rainwater exclusion experiment in primary Amazonian rainforest to test whether induced water stress and covarying changes in soil moisture, soil respiration, and tree species richness, diversity, size, and total biomass affected species richness and composition (relative abundance) of ground-dwelling ants. Data on ant abundance and environmental variables were collected at two sites (control and experimental) in the Eastern Amazon. Since 2002, drought has been induced in the experimental plot by excluding 50% of normal rainfall. Ant species richness in the experiment plot was reduced and some generalist species responded positively. Ant species richness also increased in the experimental plot with increasing diversity of the plant species of the leaf litter. The relative abundance of ants differed between plots. The experimental plot was characterized by a higher frequency of generalist and other species that appeared to be favored by the reduction in rainfall. Between-plot comparisons suggested loss and changes in ant species composition in tropical forests were affected by increasing dryness. These changes could ultimately lead to cascading effects on ecosystem processes and the services they mediate.
MeSH term(s)	Animals ; Ecosystem ; Ants ; Droughts ; Forests ; Soil
Chemical Substances	Soil
Language	English
Publishing date	2023-01-16
Publishing country	Germany
Document type	Journal Article
ZDB-ID	123369-5
ISSN	1432-1939 ; 0029-8549
ISSN (online)	1432-1939
ISSN	0029-8549
DOI	10.1007/s00442-023-05316-x
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Article ; Online: Challenges encountered by natural repellents: Since obtaining until the final product.

Almeida, Addison Ribeiro / Oliveira, Nicolas Dantas / Pinheiro, Francisco Ayrton Senna Domingos / Morais, Waldenice Alencar de / Ferreira, Leandro De Santis

Pesticide biochemistry and physiology

2023 Volume 195, Page(s) 105538

Abstract: Vector-borne diseases, particularly the arboviruses dengue, Zika, chikungunya, and yellow fever caused by the Aedes aegypti mosquito, have been driving the use of repellents worldwide. The most representative synthetic repellent, DEET stands out as the ... ...

Abstract	Vector-borne diseases, particularly the arboviruses dengue, Zika, chikungunya, and yellow fever caused by the Aedes aegypti mosquito, have been driving the use of repellents worldwide. The most representative synthetic repellent, DEET stands out as the market's oldest and most efficient repellent. It is considered a reference standard but presents considerable toxicity, not recommended for children up to 6 months old and pregnant women. For this reason, alternatives have been sought, and natural repellents derived mainly from essential oils have been studied, highlighting the essential oils of lemon (Corymbia citriodora), citronella (Cympobogon sp.), Andiroba (Carapa guianensis). However, the development and commercialization of products containing natural repellents are significantly lower when compared to DEET and other synthetic repellents. In order to understand the reasons, aspects related to safety, mechanism of action, efficacy as well development and complexity of the products were evaluated. It is concluded that, as for safety, there is lacking information in the literature regarding the effects on non-target organisms and robust toxicity data. The mechanism of action is based on theories, with less information on the exact mode of action, molecular targets, and interaction with the olfactory and taste receptors of insects. Despite being a current trend to search for actives from natural sources highly present in essential oils, however they reduced action time because due to rapid evaporation after application to the skin, thus requiring repellent vehicles. The development and complexity related to these products bring challenging aspects, beginning on the plant cultivation and extraction processes to produce essential oils with a more homogeneous chemical composition towards the formulation stabilization processes due to fast evaporation and short action time, with the use of pharmaceutical technology such as encapsulation techniques.
MeSH term(s)	Female ; Humans ; Pregnancy ; Animals ; DEET ; Mosquito Vectors ; Aedes ; Insect Repellents/pharmacology ; Oils, Volatile/pharmacology ; Zika Virus ; Zika Virus Infection
Chemical Substances	DEET (134-62-3) ; Insect Repellents ; Oils, Volatile
Language	English
Publishing date	2023-07-14
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	184819-7
ISSN	1095-9939 ; 0048-3583 ; 0048-3575
ISSN (online)	1095-9939
ISSN	0048-3583 ; 0048-3575
DOI	10.1016/j.pestbp.2023.105538
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Article ; Online: Induced drought strongly affects richness and composition of ground-dwelling ants in the eastern Amazon

Almeida, Rony P. S. / Silva, Rogério R. / da Costa, Antonio C. Lôla / Ferreira, Leandro V. / Meir, Patrick / Ellison, Aaron M.

Oecologia. 2023 Feb., v. 201, no. 2 p.299-309

2023

Abstract	Species loss in tropical regions is forecast to occur under environmental change scenarios of low precipitation. One of the main questions is how drought will affect invertebrates, a key group for ecosystem functioning. We use 1 year of data from a long-term rainwater exclusion experiment in primary Amazonian rainforest to test whether induced water stress and covarying changes in soil moisture, soil respiration, and tree species richness, diversity, size, and total biomass affected species richness and composition (relative abundance) of ground-dwelling ants. Data on ant abundance and environmental variables were collected at two sites (control and experimental) in the Eastern Amazon. Since 2002, drought has been induced in the experimental plot by excluding 50% of normal rainfall. Ant species richness in the experiment plot was reduced and some generalist species responded positively. Ant species richness also increased in the experimental plot with increasing diversity of the plant species of the leaf litter. The relative abundance of ants differed between plots. The experimental plot was characterized by a higher frequency of generalist and other species that appeared to be favored by the reduction in rainfall. Between-plot comparisons suggested loss and changes in ant species composition in tropical forests were affected by increasing dryness. These changes could ultimately lead to cascading effects on ecosystem processes and the services they mediate.
Keywords	biomass ; drought ; ecosystems ; plant litter ; rain ; rain forests ; soil respiration ; soil water ; species richness ; trees ; water stress ; Amazonia
Language	English
Dates of publication	2023-02
Size	p. 299-309.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	123369-5
ISSN	1432-1939 ; 0029-8549
ISSN (online)	1432-1939
ISSN	0029-8549
DOI	10.1007/s00442-023-05316-x
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Challenges encountered by natural repellents: Since obtaining until the final product

Almeida, Addison Ribeiro / Oliveira, Nicolas Dantas / Pinheiro, Francisco Ayrton Senna Domingos / de Morais, Waldenice Alencar / Ferreira, Leandro De Santis

Pesticide Biochemistry and Physiology. 2023, p.105538-

2023 , Page(s) 105538–

Abstract	Vector-borne diseases, particularly the arboviruses dengue, Zika, chikungunya, and yellow fever caused by the Aedes aegypti mosquito, have been driving the use of repellents worldwide. The most representative synthetic repellent, DEET stands out as the market's oldest and most efficient repellent. It is considered a reference standard but presents considerable toxicity, not recommended for children up to 6 months old and pregnant women. For this reason, alternatives have been sought, and natural repellents derived mainly from essential oils have been studied, highlighting the essential oils of lemon (Corymbia citriodora), citronella (Cympobogon sp.), Andiroba (Carapa guianensis). However, the development and commercialization of products containing natural repellents are significantly lower when compared to DEET and other synthetic repellents. In order to understand the reasons, aspects related to safety, mechanism of action, efficacy as well development and complexity of the products were evaluated. It is concluded that, as for safety, there is lacking information in the literature regarding the effects on non-target organisms and robust toxicity data. The mechanism of action is based on theories, with less information on the exact mode of action, molecular targets, and interaction with the olfactory and taste receptors of insects. Despite being a current trend to search for actives from natural sources highly present in essential oils, however they reduced action time because due to rapid evaporation after application to the skin, thus requiring repellent vehicles. The development and complexity related to these products bring challenging aspects, beginning on the plant cultivation and extraction processes to produce essential oils with a more homogeneous chemical composition towards the formulation stabilization processes due to fast evaporation and short action time, with the use of pharmaceutical technology such as encapsulation techniques.
Keywords	Aedes aegypti ; Carapa guianensis ; Corymbia citriodora ; arboviruses ; chemical composition ; commercialization ; deet ; dengue ; encapsulation ; evaporation ; lemons ; markets ; mechanism of action ; pesticides ; reference standards ; taste ; toxicity ; yellow fever ; Natural products ; Natural repellent ; Synthetic repellent ; Essential oils
Language	English
Publishing place	Elsevier Inc.
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	184819-7
ISSN	1095-9939 ; 0048-3583 ; 0048-3575
ISSN (online)	1095-9939
ISSN	0048-3583 ; 0048-3575
DOI	10.1016/j.pestbp.2023.105538
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Article ; Online: Natural regeneration triggers compositional and functional shifts in soil seed banks.

Medeiros-Sarmento, Priscila Sanjuan de / Ferreira, Leandro Valle / Gastauer, Markus

The Science of the total environment

2020 Volume 753, Page(s) 141934

Abstract: Secondary forests emerging during traditional shifting cultivation practices are increasingly recognized for their fulfillment of ecosystem services and mitigation potential of climate change and biodiversity losses. The soil seed bank as a recruit ... ...

Abstract	Secondary forests emerging during traditional shifting cultivation practices are increasingly recognized for their fulfillment of ecosystem services and mitigation potential of climate change and biodiversity losses. The soil seed bank as a recruit reservoir is a limiting factor for natural forest regeneration of such secondary forests and is decisive for the formation and restitution of the post-disturbance community. The aim of this study was to compare the composition of the soil seed bank along a natural regeneration chronosequence from the Caxiuanã National Forest, eastern Amazon, including old-growth reference sites. We sampled standing vegetation, soil properties and soil seed banks and compared the density and species richness of different life forms among different regeneration stages. Using nonmetric, multiple scaling, we compared the composition of the soil seed bank among different regeneration stages and with standing vegetation composition. Furthermore, we outlined the influence of stand age, vegetation structure and soil properties on the density, richness and functional characterization of the soil seed bank using mixed effect models. The soil seed bank was dominated by herb seeds in all regeneration stages, and the density and richness of tree seeds increased with regeneration time and recovery of vegetation structure. Seed bank composition changed gradually with regeneration advance and differed from standing vegetation, containing a high amount of allochthonous seeds, especially in older stands. This observation highlights the importance of dispersal and habitat connectivity for the natural regeneration of these secondary forests. Shifts in soil seed bank composition towards slow-growing, animal-dispersed, non-pioneer species with larger, recalcitrant seeds in older regeneration stands indicate changes in vegetation composition along succession. Thus, our data indicate the importance of connectivity for forest regeneration and long fallow periods (> 40 years) to increase the performance of ecosystem services, resilience and stability of secondary forests arising during shifting cultivation practices.
MeSH term(s)	Ecosystem ; Forests ; Seed Bank ; Seeds ; Soil ; Trees
Chemical Substances	Soil
Language	English
Publishing date	2020-08-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2020.141934
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Article ; Online: Neural Mobilization Short-Term Dose Effect on the Lower-Limb Flexibility and Performance in Basketball Athletes: A Randomized, Parallel, and Single-Blinded Study.

Pereira, Andreia / Teixeira, Cátia / Pereira, Karla / Ferreira, Leandro / Marques, Maria / Silva, Anabela G

Journal of sport rehabilitation

2021 Volume 30, Issue 7, Page(s) 1060–1066

Abstract: Context: Neural mobilization is commonly used in sports, and previous studies have suggested that it has a positive impact on lower-limb flexibility and performance. However, studies exploring the effect of neural mobilization dosage are almost ... ...

Abstract	Context: Neural mobilization is commonly used in sports, and previous studies have suggested that it has a positive impact on lower-limb flexibility and performance. However, studies exploring the effect of neural mobilization dosage are almost nonexistent. Objectives: This study aimed to assess whether 2 distinct dosages of neural gliding mobilization (4 and 8 sets of 10 repetitions) impact the flexibility and performance of both the mobilized and nonmobilized lower limb in basketball athletes differently. Design: Randomized, parallel, and single-blinded study. Setting: Amateur and professional basketball clubs. Participants: Fifty-two basketball athletes (40 men and 12 women), who were distributed into 2 groups; one received 40 (n = 28) and the other 80 repetitions (n = 24) of neural gliding mobilization. Intervention: Neural gliding mobilization applied to a single limb (the dominant limb). Main outcome measures: Knee extension angle for hamstring flexibility; hop tests and single-leg vertical jump for performance. Results: There was a significant main effect of time (P < .001), a significant interaction between time and limb for flexibility (P = .003), and a significant interaction between time and limb for the single-leg hop test (P = .032). No other significant main effect for any of the remaining variables was found (P > .05). Conclusions: The application of both 40 repetitions and 80 of neural gliding significantly improved lower-limb flexibility, and one was not superior to the other. Neither one dosage nor the other positively or negatively impacted the lower-limb performance of basketball athletes.
MeSH term(s)	Athletes ; Basketball ; Female ; Humans ; Knee Joint ; Lower Extremity ; Male
Language	English
Publishing date	2021-05-25
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	1106769-x
ISSN	1543-3072 ; 1056-6716
ISSN (online)	1543-3072
ISSN	1056-6716
DOI	10.1123/jsr.2020-0389
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Article ; Online: LICENCIATURA EM EDUCAÇÃO DO CAMPO

José Antonio Ferreira Leandro / Keylla Rejane Almeida Melo / Catarina de Bortoli Munhae

Cadernos Cajuína, Vol 5, Iss 3, Pp 77-

O TEMPO COMUNIDADE COMO POTENCIALIZADOR DE UMA FORMAÇÃO DOCENTE CRÍTICA E TRANSFORMADORA

2020 Volume 88

Abstract: A Pedagogia da Alternância tem demonstrado sua viabilidade no atendimento às populações campesinas. A integração entre diferentes tempos e espaços formativos traz uma nova perspectiva para as universidades, no sentido de articular efetivamente ensino, ... ...

Abstract	A Pedagogia da Alternância tem demonstrado sua viabilidade no atendimento às populações campesinas. A integração entre diferentes tempos e espaços formativos traz uma nova perspectiva para as universidades, no sentido de articular efetivamente ensino, pesquisa e extensão e favorecer a relação indissociável entre teoria e prática. O objetivo deste trabalho é apresentar resultados do projeto de intervenção “Horta pedagógica como instrumento de ensino-aprendizagem para uma educação contextualizada”, realizado de 2016 a 2018, na Escola Zenita Pires Ferreira, localizada na comunidade São Joaquim, zona rural de Campo Maior (PI). Participaram do projeto, educandos do 5º, 6º e 9º anos do Ensino Fundamental, além de professores, secretário da escola, como também, algumas famílias da comunidade. Apesar dos inúmeros desafios, o trabalho foi produtivo para a escola, pois a utilização da horta apresentou-se como uma ferramenta instrumental e norteadora para os educadores na forma de ensinar os conteúdos curriculares, tornando suas aulas mais agradáveis e significativas. A horta pedagógica possibilitou aos estudantes trabalharem em grupo e observarem como a natureza age, vivenciando na prática conhecimentos teóricos. A execução do projeto demonstrou que este trabalho atraiu a participação engajada de alunos e professores, além de ter promovido interação entre eles.
Keywords	Education ; L ; Social Sciences ; H
Language	Portuguese
Publishing date	2020-09-01T00:00:00Z
Publisher	Instituto Federal de Educação, Ciência e Tecnologia do Piauí
Document type	Article ; Online
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Article ; Online: Anti-inflammatory, healing and antiophidic potential of Jatropha mollissima (Pohl) Baill. (Euphorbiaceae): From popular use to pharmaceutical formulation in gel.

Passos, Júlia G R / Gomes, Jacyra A S / Xavier-Santos, Jacinthia B / Yamashita, Fabiana O / Cavalcanti-Cruz, Joelly V / Siqueira, Emerson M S / Garcia, Vinícius Barreto / Zucolotto, Silvana M / de Araujo-Junior, Raimundo Fernandes / Ferreira, Leandro S / Silva-Junior, Arnóbio A / Félix-Silva, Juliana / Fernandes-Pedrosa, Matheus F

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2024 Volume 173, Page(s) 116290

Abstract: Jatropha mollissima (Pohl) Baill. (Euphorbiaceae) is widely used in traditional medicine to treat inflammatory disorders. So, a topical gel containing the hydroethanolic extract of its leaves was developed and evaluated for its anti-inflammatory, wound ... ...

Abstract	Jatropha mollissima (Pohl) Baill. (Euphorbiaceae) is widely used in traditional medicine to treat inflammatory disorders. So, a topical gel containing the hydroethanolic extract of its leaves was developed and evaluated for its anti-inflammatory, wound healing, and antiophidic properties in mice. First, the chemical profile of different parts of the plant was characterized by liquid chromatography coupled to mass spectrometry (LC-MS) using molecular networking. In the leaf extract, 11 compounds were characterized, with a particular emphasis on the identification of flavonoids. The gel efficiently inhibited carrageenan-induced paw edema, as well as acute and chronic croton oil-induced ear edema models, thereby reducing inflammatory and oxidative parameters in inflamed tissues. Besides anti-inflammatory activity, the herbal gel showed significant wound healing activity. The edematogenic, hemorrhagic and dermonecrotic activities induced by Bothrops jararaca snake venom were effectively inhibited by the treatment with J. mollissima gel. The association with the herbal gel improved in up to 90% the efficacy of commercial snake antivenom in reduce venom-induced edema. Additionally, while antivenom was not able to inhibit venom-induced dermonecrosis, treatment with herbal gel reduced in 55% the dermonocrotic halo produced. These results demonstrate the pharmacological potential of the herbal gel containing J. mollissima extract, which could be a strong candidate for the development of herbal products that can be used to complement the current antivenom therapy against snake venom local toxicity.
MeSH term(s)	Animals ; Mice ; Euphorbiaceae/chemistry ; Antivenins/pharmacology ; Plant Extracts/pharmacology ; Plant Extracts/therapeutic use ; Plant Extracts/chemistry ; Jatropha/chemistry ; Drug Compounding ; Crotalid Venoms ; Snake Bites/drug therapy ; Edema/chemically induced ; Edema/drug therapy ; Anti-Inflammatory Agents/adverse effects ; Bothrops jararaca Venom ; Wound Healing
Chemical Substances	Antivenins ; Plant Extracts ; Crotalid Venoms ; Anti-Inflammatory Agents ; Bothrops jararaca Venom
Language	English
Publishing date	2024-03-07
Publishing country	France
Document type	Journal Article
ZDB-ID	392415-4
ISSN	1950-6007 ; 0753-3322 ; 0300-0893
ISSN (online)	1950-6007
ISSN	0753-3322 ; 0300-0893
DOI	10.1016/j.biopha.2024.116290
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