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  1. Article ; Online: Total laryngectomy: A new lateral cervical approach.

    Spriano, G / Mercante, G / Pellini, R / Ferreli, F

    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

    2017  Volume 43, Issue 2, Page(s) 784–785

    MeSH term(s) Humans ; Laryngectomy/methods ; Neck Dissection/methods
    Language English
    Publishing date 2017-07-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2205891-6
    ISSN 1749-4486 ; 1749-4478 ; 0307-7772 ; 1365-2273
    ISSN (online) 1749-4486
    ISSN 1749-4478 ; 0307-7772 ; 1365-2273
    DOI 10.1111/coa.12920
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1309: Show issues Location:
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  2. Article ; Online: The impact of frailty on adjuvant treatment in patients with head and neck free flap reconstruction-A retrospective study using two independent frailty scores: Avoiding the wrong conclusion.

    Festa, Bianca Maria / Costantino, Andrea / Ferreli, Fabio / Spriano, Giuseppe / Mercante, Giuseppe / De Virgilio, Armando

    Oral oncology

    2022  Volume 134, Page(s) 106071

    MeSH term(s) Frailty ; Free Tissue Flaps ; Head and Neck Neoplasms/etiology ; Head and Neck Neoplasms/surgery ; Humans ; Neck ; Postoperative Complications/etiology ; Reconstructive Surgical Procedures/adverse effects ; Retrospective Studies
    Language English
    Publishing date 2022-08-15
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2022.106071
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    Zs.A 4869: Show issues Location:
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  3. Article ; Online: A critical analysis of the classifications of squamous cell carcinoma of the nasal vestibule.

    Ferreli, Fabio / Pirola, Francesca / Di Santo, Davide / De Virgilio, Armando / Spriano, Giuseppe / Mercante, Giuseppe

    Oral oncology

    2022  Volume 129, Page(s) 105880

    MeSH term(s) Carcinoma, Squamous Cell/pathology ; Humans ; Nasal Cavity/pathology ; Nose Neoplasms/pathology
    Language English
    Publishing date 2022-04-28
    Publishing country England
    Document type Letter
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2022.105880
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  4. Article ; Online: High-Definition 3D Exoscope in Thyroid Surgery.

    Mercante, Giuseppe / Costantino, Andrea / De Virgilio, Armando / Ferreli, Fabio / Spriano, Giuseppe

    Surgical innovation

    2022  Volume 30, Issue 2, Page(s) 205–209

    Abstract: Background: The high-definition 3D exoscope is an innovative and promising tool that was recently introduced in the clinical practice. It may be used during open surgical procedures to enhance the ability to perform precise dissection of fine structures. ...

    Abstract Background: The high-definition 3D exoscope is an innovative and promising tool that was recently introduced in the clinical practice. It may be used during open surgical procedures to enhance the ability to perform precise dissection of fine structures. We describe our preliminary experience with the 3D exoscope in thyroid surgery, discussing potential advantages of this system.
    Methods: A high-definition 3D exoscope (3D VITOM
    Results: The 3D exoscope was used in three patients without significant intra-operative delay or complications. Both thyroidectomy and central compartment dissection were performed. The 3D exoscope allows to perform precise dissection in the identification and preservation of the recurrent laryngeal nerve and the parathyroid glands.
    Conclusions: 3D exoscope-assisted thyroid surgery seems to be feasible and safe. Further studies should be encouraged to analyze potential clinical benefit in the post-operative period.
    MeSH term(s) Humans ; Thyroid Gland/surgery ; Parathyroid Glands ; Thyroidectomy/methods ; Dissection ; Germany
    Language English
    Publishing date 2022-05-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2182571-3
    ISSN 1553-3514 ; 1553-3506
    ISSN (online) 1553-3514
    ISSN 1553-3506
    DOI 10.1177/15533506221097553
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    Zs.A 4269: Show issues Location:
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  5. Article ; Online: A new lateral cervical approach for salvage total laryngo-pharyngectomy.

    Spriano, G / Mercante, G / Manciocco, V / Cristalli, G / Sanguineti, G / Ferreli, F

    Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale

    2019  Volume 39, Issue 1, Page(s) 61–64

    MeSH term(s) Aged ; Carcinoma, Squamous Cell/surgery ; Dermatologic Surgical Procedures ; Humans ; Hyoid Bone/surgery ; Hypopharyngeal Neoplasms/surgery ; Hypopharynx/surgery ; Laryngeal Neoplasms/surgery ; Laryngectomy/methods ; Larynx/surgery ; Male ; Myocutaneous Flap ; Neck/surgery ; Neck Dissection/methods ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/surgery ; Pectoralis Muscles/surgery ; Pharyngectomy/methods ; Pharynx/pathology ; Pharynx/surgery ; Reconstructive Surgical Procedures ; Salvage Therapy/methods ; Surgical Flaps
    Language English
    Publishing date 2019-04-01
    Publishing country Italy
    Document type Case Reports
    ZDB-ID 604898-5
    ISSN 1827-675X ; 0392-100X
    ISSN (online) 1827-675X
    ISSN 0392-100X
    DOI 10.14639/0392-100X-1753
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    Zs.B 2608: Show issues Location:
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  6. Article ; Online: Endoscopic Trans-Sphenoidal Resection of a Giant Pituitary Neuroendocrine Tumor with Third Ventricle Invasion and Obstructive Hydrocephalus: Surgical Anatomy and Two-Dimensional Operative Video.

    Bono, Beatrice C / Milani, Davide / Ferreli, Fabio / Olei, Simone / Raspagliesi, Luca / Tropeano, Maria Pia / Lasio, Giovanni B / Pessina, Federico

    World neurosurgery

    2023  Volume 181, Page(s) 107

    MeSH term(s) Humans ; Third Ventricle/diagnostic imaging ; Third Ventricle/surgery ; Third Ventricle/pathology ; Neuroendocrine Tumors ; Endoscopy/methods ; Pituitary Neoplasms/complications ; Pituitary Neoplasms/diagnostic imaging ; Pituitary Neoplasms/surgery ; Hydrocephalus/diagnostic imaging ; Hydrocephalus/etiology ; Hydrocephalus/surgery
    Language English
    Publishing date 2023-10-21
    Publishing country United States
    Document type Video-Audio Media
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2023.10.075
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    Zs.A 1159: Show issues Location:
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  7. Article ; Online: Airways Type-2 Related Disorders: Multiorgan, Systemic or Syndemic Disease?

    Giombi, Francesco / Pace, Gian Marco / Pirola, Francesca / Cerasuolo, Michele / Ferreli, Fabio / Mercante, Giuseppe / Spriano, Giuseppe / Canonica, Giorgio Walter / Heffler, Enrico / Ferri, Sebastian / Puggioni, Francesca / Paoletti, Giovanni / Malvezzi, Luca

    International journal of molecular sciences

    2024  Volume 25, Issue 2

    Abstract: Chronic rhinosinusitis (CRS) has recently undergone a significant paradigm shift, moving from a phenotypical classification towards an "endotype-based" definition that places more emphasis on clinical and therapeutic aspects. Similar to other airway ... ...

    Abstract Chronic rhinosinusitis (CRS) has recently undergone a significant paradigm shift, moving from a phenotypical classification towards an "endotype-based" definition that places more emphasis on clinical and therapeutic aspects. Similar to other airway diseases, like asthma, most cases of CRS in developed countries exhibit a dysregulated type-2 immune response and related cytokines. Consequently, the traditional distinction between upper and lower airways has been replaced by a "united airway" perspective. Additionally, type-2 related disorders extend beyond respiratory boundaries, encompassing conditions beyond the airways, such as atopic dermatitis. This necessitates a multidisciplinary approach. Moreover, consideration of possible systemic implications is crucial, particularly in relation to sleep-related breathing diseases like Obstructive Sleep Apnoea Syndrome (OSAS) and the alteration of systemic inflammatory mediators such as nitric oxide. The trends in epidemiological, economic, and social burden are progressively increasing worldwide, indicating syndemic characteristics. In light of these insights, this narrative review aims to present the latest evidence on respiratory type-2 related disorders, with a specific focus on CRS while promoting a comprehensive perspective on the "united airways". It also introduces a novel concept: viewing these conditions as a multiorgan, systemic, and syndemic disease.
    MeSH term(s) Humans ; Syndemic ; Asthma/epidemiology ; Sleep Apnea, Obstructive/epidemiology ; Sleep Apnea, Obstructive/therapy ; Respiration ; Cytokines ; Sleep Wake Disorders
    Chemical Substances Cytokines
    Language English
    Publishing date 2024-01-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25020730
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  8. Article ; Online: Fatal Iatrogenic Pituitary Apoplexy after Surgery for Neuroophthalmological Disorder.

    Nioi, Matteo / Napoli, Pietro Emanuele / Ferreli, Fabio

    Anesthesiology

    2019  Volume 130, Issue 5, Page(s) 822

    MeSH term(s) Adenoma/surgery ; Fatal Outcome ; Female ; Humans ; Iatrogenic Disease ; Middle Aged ; Pituitary Apoplexy/etiology ; Pituitary Neoplasms/surgery ; Postoperative Complications/etiology ; Vision Disorders/surgery
    Language English
    Publishing date 2019-01-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000002584
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  9. Article: Outcomes of Endoscopic Endonasal Dacryocystorhinostomy in Glaucoma Patients.

    Pace, Gian Marco / Giombi, Francesco / Muci, Giovanna / Giunta, Gianmarco / Pirola, Francesca / Serra, Egidio / Zuppardo, Jessica / Ferreli, Fabio / Vinciguerra, Paolo / Mercante, Giuseppe / Maria, Alessandra Di / Spriano, Giuseppe / Malvezzi, Luca

    Journal of personalized medicine

    2024  Volume 14, Issue 4

    Abstract: Background: Anti-glaucoma eye drops have been investigated due to their production of fibrotic changes on the conjunctival surface, undermining the functioning of the upper lacrimal drainage system. We aimed to assess whether these effects may impair ... ...

    Abstract Background: Anti-glaucoma eye drops have been investigated due to their production of fibrotic changes on the conjunctival surface, undermining the functioning of the upper lacrimal drainage system. We aimed to assess whether these effects may impair the effectiveness of endoscopic endonasal dacryocystorhinostomy (EE-DCR).
    Methods: This is a single-center observational retrospective study on EE-DCR via a posterior approach. Resolution of epiphora and dacryocystitis were analyzed after 1 (T1) and 6-months (T2) from surgery. Surgical success was defined as anatomical (patency at irrigation, no recurring dacryocystitis) or complete (zeroing of Munk score).
    Results: Twenty patients (32 sides) were enrolled. Preoperatively, 93.75% (
    Conclusions: Despite the chronic uptake of anti-glaucoma eye drops, EE-DCR guaranteed high rates of clinical relief from epiphora and remarkable decreases in the rates of recurrent dacryocystitis.
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm14040348
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  10. Article ; Online: Lateral conservative approach for recurrent/persistent hypopharyngeal carcinoma: a case series.

    Cristalli, G / Ferri, E / Di Maio, P / Spriano, G / Mercante, G / Ferreli, F / Pellini, R / Boscolo Nata, F

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2020  Volume 277, Issue 8, Page(s) 2375–2380

    Abstract: Purpose: Early persistent/recurrent hypopharyngeal tumours represent a challenge for surgeons who have to balance the need for oncological radicality and the desire to maintain a functioning larynx with preservation of the patient's quality of life. The ...

    Abstract Purpose: Early persistent/recurrent hypopharyngeal tumours represent a challenge for surgeons who have to balance the need for oncological radicality and the desire to maintain a functioning larynx with preservation of the patient's quality of life. The aim of this study was primarily to understand the technical feasibility, functional outcomes, and the possibility of obtaining oncological radicality using lateral hypopharyngectomy with laryngeal preservation in early recurrent post-radio/(chemo)therapy hypopharyngeal tumours.
    Methods: Patients with recurrent T1 hypopharyngeal squamous cell carcinoma were retrospectively selected from our institutional database. The external lateral approach according to Spriano and a modified lateral hypopharyngectomy with laryngeal preservation were used to resect tumours of the lateral pyriform sinus wall. Reconstruction was obtained by direct approximation of the posterior border of the sectioned thyroid cartilage to the posterior hypopharyngeal wall, and this was reinforced with a second layer of vascularised and non-irradiated tissue that was provided by a microvascular fascial anterobrachial flap. Swallowing was assessed 3 weeks after surgery using videoendoscopic evaluation.
    Results: The surgical procedure was technically feasible, and complete resection was obtained in all patients. None of the patients experienced major post-operative complications (salivary fistula, bleeding, aspiration pneumonia). Mild dysphagia was observed in one patient who underwent swallowing rehabilitation. Tracheostomy was closed in all patients. No recurrence was recorded after a median follow-up of 20 months.
    Conclusion: The reported experience shows that, in selected cases, it is possible to radically remove lateral hypopharyngeal cancer with acceptable functional results.
    MeSH term(s) Head and Neck Neoplasms ; Humans ; Hypopharyngeal Neoplasms/surgery ; Laryngectomy ; Neoplasm Recurrence, Local/surgery ; Pharyngectomy ; Quality of Life ; Retrospective Studies
    Language English
    Publishing date 2020-05-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-020-06009-4
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