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  1. Article ; Online: Hipertensión intraabdominal y síndrome compartimental abdominal.

    Piacentini, Enrique / Ferrer Pereto, Carles

    Enfermedades infecciosas y microbiologia clinica

    2010  Volume 28 Suppl 2, Page(s) 2–10

    Abstract: Although intraabdominal pressure (IAP) has been studied for more than 100 years, the concepts of intraabdominal hypertension (IAH) and abdominal compartmental syndrome (ACS) have only been developed as clinical entities of interest in intensive care in ... ...

    Title translation Intraabdominal hypertension and abdominal compartment syndrome.
    Abstract Although intraabdominal pressure (IAP) has been studied for more than 100 years, the concepts of intraabdominal hypertension (IAH) and abdominal compartmental syndrome (ACS) have only been developed as clinical entities of interest in intensive care in the last 5 years. At the first Congress on Abdominal Compartment Syndrome in December 2004, a series of definitions were established, which were published in 2006. IAH is defined as IAP ≥ 12 mmHg and is classified in four severity grades, the maximum grade being ACS, with the development of multiorgan failure. The incidence of IAH in patients in intensive care units is high, around 30% at admission and 64% in those with a length of stay of 7 days. The increase in IAP leads to reduced vascular flow to the splenic organs, increased intrathoracic pressure and decreased venous return, with a substantial reduction in cardiac output. If IAH persists, these physiopathologic episodes are followed by the development of multiorgan failure with renal, cardiocirculatory and respiratory failure and intestinal ischemia. Mortality from untreated ACS is higher than 60%. The only treatment for ACS is surgical decompression. In patients with moderate IAH, medical treatment should be optimized, based on the following measures: a) serial IAP monitoring; b) optimization of systemic perfusion and the function of the distinct systems in patients with high IAP; c) instauration of specific measures to decrease IAP; and d) early surgical decompression for refractory IAH. The application of the medical measures that can reduce IAP and early abdominal decompression in ACS improve survival in critically ill patients with IAH.
    MeSH term(s) Abdomen ; Algorithms ; Animals ; Ascites/complications ; Central Nervous System/physiopathology ; Compartment Syndromes/drug therapy ; Compartment Syndromes/epidemiology ; Compartment Syndromes/etiology ; Compartment Syndromes/physiopathology ; Compartment Syndromes/surgery ; Critical Care ; Decompression, Surgical ; Diuretics/therapeutic use ; Fluid Therapy ; Gastrointestinal Tract/physiopathology ; Glomerular Filtration Rate ; Hemodynamics ; Humans ; Hypnotics and Sedatives/therapeutic use ; Incidence ; Intubation, Gastrointestinal ; Manometry/methods ; Neuromuscular Blocking Agents/therapeutic use ; Pressure ; Renal Insufficiency/etiology ; Renal Insufficiency/physiopathology
    Chemical Substances Diuretics ; Hypnotics and Sedatives ; Neuromuscular Blocking Agents
    Language Spanish
    Publishing date 2010-09
    Publishing country Spain
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 1070941-1
    ISSN 1578-1852 ; 0213-005X
    ISSN (online) 1578-1852
    ISSN 0213-005X
    DOI 10.1016/S0213-005X(10)70024-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Evaluation of Nutritional Practices in the Critical Care patient (The ENPIC study): Does nutrition really affect ICU mortality?

    Servia-Goixart, Lluís / Lopez-Delgado, Juan C. / Grau-Carmona, Teodoro / Trujillano-Cabello, Javier / Bordeje-Laguna, M Luisa / Mor-Marco, Esther / Portugal-Rodriguez, Esther / Lorencio-Cardenas, Carol / Montejo-Gonzalez, Juan C. / Vera-Artazcoz, Paula / Macaya-Redin, Laura / Martinez-Carmona, Juan Francisco / Iglesias-Rodriguez, Rayden / Monge-Donaire, Diana / Flordelis-Lasierra, José L. / Llorente-Ruiz, Beatriz / Menor-Fernández, Eva M. / Martínez de Lagrán, Itziar / Yebenes-Reyes, Juan C. /
    Escobar-Ortiz, Joan / Montserrat-Ortiz, Neus / Zapata-Rojas, Amalia / Bautista-Redondo, Iris / Cruz-Ramos, Ana / Diaz-Castellanos, Laura / Morales-Cifuentes, Miriam / Bono, Montserrat Plaza- / Montejo-Gonzalez, Juan Carlos / Temprano-Vazquez, Susana / Arjona-Diaz, Veronica / Garcia-Fuentes, Carlos / Mudarra-Reche, Carolina / Orejana-Martin, Maria / Lopez-Delgado, Juan Carlos / Lores-Obradors, Africa / Anguela-Calvet, Laura / Muñoz-Del Río, Gloria / Revelo-Esquibel, Pamela Alejandra / Alanez-Saavedra, Henry / Serra-Paya, Pau / Luna-Solis, Stephani Maria / Salinas-Canovas, Alvaro / De Frutos-Seminario, Fernando / Rodriguez-Queralto, Oriol / Gonzalez-Iglesias, Carlos / Zamora-Elson, Monica / Fuente-O'Connor, Eugenia de la / Arbeloa, Carlos Seron- / Bueno-Vidales, Nestor / Martin-Luengo, Ana / Sanchez-Miralles, Angel / Marmol-Peis, Enrique / Ruiz-Miralles, Miriam / Gonzalez-Sanz, Maria / Server-Martinez, Arantzazu / Vila-Garcia, Belen / Flecha-Viguera, Raquel / Aldunate-Calvo, Sara / Flordelis-Lasierra, Jose Luis / Rio, Irene Jimenez-del / Mampaso-Recio, Jose Ramon / Rodriguez-Roldan, Jose Manuel / Gastaldo-Simeon, Rosa / Gimenez-Castellanos, Josefina / Fernandez-Ortega, Juan Francisco / Martinez-Carmona, Juan F. / Lopez-Luque, Esther / Ortega-Ordiales, Ane / Crespo-Gomez, Monica / Ramirez-Montero, Victor / Lopez-García, Esther / Navarro-Lacalle, Arturo / Martinez-Garcia, Pilar / Dominguez-Fernandez, Maria Inmaculada / Izura-Gomez, Marta / Hernandez-Duran, Susana / Bordeje-Laguna, Ma Luisa / Rovira-Valles, Yaiza / Philibert, Viridiana / Alcazar-Espin, Maravillas de las Nieves / Higon-Cañigral, Aurea / Calvo-Herranz, Enrique / Manzano-Moratinos, Diego / Andaluz-Ojeda, David / Parra-Morais, Laura / Citores-Gonzalez, Rafael / Garcia-Gonzalez, Maria Teresa / Sanchez-Giron, Gloria Renedo / Navas-Moya, Elisabeth / Ferrer-Pereto, Carles / Lluch-Candal, Cristina / Ruiz-Izquierdo, Jessica / Castor-Bekari, Silvia / Leon-Cinto, Cristina / Martinez de Lagran, Itziar / Yebenes-Reyes, Juan Carlos / Nieto-Martino, Beatriz / Vaquerizo-Alonso, Clara / Almanza-Lopez, Susana / Perez-Quesada, Sonia / Anton-Pascual, Jose Luis / Marin-Corral, Judith / Sistachs-Baquedano, Maite / Hacer-Puig, Maria / Picornell-Noguera, Marina / Mateu-Campos, Lidon / Martinez-Valero, Clara / Ortiz-Suñer, Andrea / Martinez-Diaz, María Cristina / Muñoz De La Peña, Maria Trascasa- / Rodriguez-Serrano, Diego Anibal / Fernandez-Salvatierra, Leticia / Barcelo-Castello, Mireia / Millan-Taratiel, Paula / Tejada-Artigas, Antonio / Martinez-Arroyo, Ines / Araujo-Aguilar, Pilar / Fuster-Cabre, Maria / Andres-Gines, Laura / Soldado-Olmo, Sonia / Menor-Fernandez, Eva Mª / Lage-Cendon, Lucas / Touceda-Bravo, Alberto / Sanchez-Ales, Laura / Almorin-Gonzalvez, Laura / Gero-Escapa, Maria / Martinez-Barrio, Esther / Ossa-Echeverri, Sergio

    Clinical nutrition ESPEN. 2022 Feb., v. 47

    2022  

    Abstract: The importance of artificial nutritional therapy is underrecognized, typically being considered an adjunctive rather than a primary therapy. We aimed to evaluate the influence of nutritional therapy on mortality in critically ill patients.This ... ...

    Institution ENPIC Study Investigators
    Abstract The importance of artificial nutritional therapy is underrecognized, typically being considered an adjunctive rather than a primary therapy. We aimed to evaluate the influence of nutritional therapy on mortality in critically ill patients.This multicenter prospective observational study included adult patients needing artificial nutritional therapy for >48 h if they stayed in one of 38 participating intensive care units for ≥72 h between April and July 2018. Demographic data, comorbidities, diagnoses, nutritional status and therapy (type and details for ≤14 days), and outcomes were registered in a database. Confounders such as disease severity, patient type (e.g., medical, surgical or trauma), and type and duration of nutritional therapy were also included in a multivariate analysis, and hazard ratios (HRs) and 95% confidence intervals (95%CIs) were reported.We included 639 patients among whom 448 (70.1%) and 191 (29.9%) received enteral and parenteral nutrition, respectively. Mortality was 25.6%, with non-survivors having the following characteristics: older age; more comorbidities; higher Sequential Organ Failure Assessment (SOFA) scores (6.6 ± 3.3 vs 8.4 ± 3.7; P < 0.001); greater nutritional risk (Nutrition Risk in the Critically Ill [NUTRIC] score: 3.8 ± 2.1 vs 5.2 ± 1.7; P < 0.001); more vasopressor requirements (70.4% vs 83.5%; P=0.001); and more renal replacement therapy (12.2% vs 23.2%; P=0.001). Multivariate analysis showed that older age (HR: 1.023; 95% CI: 1.008–1.038; P=0.003), higher SOFA score (HR: 1.096; 95% CI: 1.036–1.160; P=0.001), higher NUTRIC score (HR: 1.136; 95% CI: 1.025–1.259; P=0.015), requiring parenteral nutrition after starting enteral nutrition (HR: 2.368; 95% CI: 1.168–4.798; P=0.017), and a higher mean Kcal/Kg/day intake (HR: 1.057; 95% CI: 1.015–1.101; P=0.008) were associated with mortality. By contrast, a higher mean protein intake protected against mortality (HR: 0.507; 95% CI: 0.263–0.977; P=0.042).Old age, higher organ failure scores, and greater nutritional risk appear to be associated with higher mortality. Patients who need parenteral nutrition after starting enteral nutrition may represent a high-risk subgroup for mortality due to illness severity and problems receiving appropriate nutritional therapy. Mean calorie and protein delivery also appeared to influence outcomes.ClinicaTrials.gov NCT: 03634943.
    Keywords adults ; clinical nutrition ; databases ; disease severity ; enteral feeding ; hemodialysis ; mortality ; multivariate analysis ; nutrition risk assessment ; nutritional status ; observational studies ; parenteral feeding ; patients ; protein intake ; risk
    Language English
    Dates of publication 2022-02
    Size p. 325-332.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 2405-4577
    DOI 10.1016/j.clnesp.2021.11.018
    Database NAL-Catalogue (AGRICOLA)

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