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  1. Article ; Online: Preface: Bowel endometriosis.

    Ferrero, Simone

    Best practice & research. Clinical obstetrics & gynaecology

    2021  Volume 71, Page(s) 1

    Language English
    Publishing date 2021-02-11
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2050090-7
    ISSN 1532-1932 ; 1521-6934
    ISSN (online) 1532-1932
    ISSN 1521-6934
    DOI 10.1016/j.bpobgyn.2021.02.001
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  2. Article ; Online: Methotrexate treatment in hand osteoarthritis refractory to usual treatments: A randomised, double-blind, placebo-controlled trial.

    Ferrero, Stephanie / Roux, Christian Hubert

    Seminars in arthritis and rheumatism

    2024  Volume 67, Page(s) 152459

    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Letter
    ZDB-ID 120247-9
    ISSN 1532-866X ; 0049-0172
    ISSN (online) 1532-866X
    ISSN 0049-0172
    DOI 10.1016/j.semarthrit.2024.152459
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    Zs.A 790: Show issues Location:
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  3. Article: Editorial: Endometriosis: pathogenesis, diagnosis and treatment, volume II.

    Ferrero, Simone / Dutta, Mainak

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1334596

    MeSH term(s) Female ; Humans ; Endometriosis/diagnosis ; Endometriosis/therapy ; Endometriosis/genetics ; Epigenesis, Genetic ; Gene Expression Regulation
    Language English
    Publishing date 2023-12-18
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1334596
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  4. Article ; Online: Proteomics in the Diagnosis of Endometriosis: Opportunities and Challenges.

    Ferrero, Simone

    Proteomics. Clinical applications

    2019  Volume 13, Issue 3, Page(s) e1800183

    Abstract: The non-surgical diagnosis of endometriosis is still challenging for the clinician. Ultrasonography and magnetic resonance imaging can be used to diagnose ovarian endometriotic cysts and deep infiltrating endometriosis; but their performance is poor in ... ...

    Abstract The non-surgical diagnosis of endometriosis is still challenging for the clinician. Ultrasonography and magnetic resonance imaging can be used to diagnose ovarian endometriotic cysts and deep infiltrating endometriosis; but their performance is poor in the diagnosis of initial stages of endometriosis. CA-125 and other serum markers (such as CA 19-9, serum protein PP14, interleukins, and angiogenetic factors) have been measured in women with endometriosis but they are not reliable for the diagnosis of the disease. Although several studies used proteomics technologies to identify plasmatic markers of endometriosis, the non-invasive diagnosis of endometriosis is far from being achieved. In this issue, Manousopoulou et al. compare the integrated quantitative proteomic profile of eutopic endometrium and serum of women with endometriosis and controls. 1214 proteins are differentially expressed in the eutopic endometrium and 404 proteins in the serum of the two study groups. 21 proteins are aberrantly expressed in both eutopic endometrium and serum of women with endometriosis. More work is needed to assess if the differentially expressed proteins identified in this study can be used as clinical markers of endometriosis.
    MeSH term(s) Case-Control Studies ; Endometriosis/diagnosis ; Endometriosis/metabolism ; Female ; Humans ; Proteomics
    Language English
    Publishing date 2019-01-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2261788-7
    ISSN 1862-8354 ; 1862-8346
    ISSN (online) 1862-8354
    ISSN 1862-8346
    DOI 10.1002/prca.201800183
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  5. Article ; Online: Looking for a needle in the haystack of CLL.

    Ferrero, Simone / Genuardi, Elisa

    Blood

    2022  Volume 141, Issue 5, Page(s) 445–447

    MeSH term(s) Humans ; Leukemia, Lymphocytic, Chronic, B-Cell ; Prognosis
    Language English
    Publishing date 2022-12-19
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2022018077
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  6. Article: Radiological environmental monitoring of groundwater around NPP: A proposal for its assessment.

    Petisco-Ferrero, S / Idoeta, R / Rozas, S / Olondo, C / Herranz, M

    Heliyon

    2023  Volume 9, Issue 9, Page(s) e19470

    Abstract: Whether a nuclear installation has radiological impact and, in that case, its extension, are the questions behind any environmental analysis of the installation along its operational life. This analysis is based on the detailed establishment of the ... ...

    Abstract Whether a nuclear installation has radiological impact and, in that case, its extension, are the questions behind any environmental analysis of the installation along its operational life. This analysis is based on the detailed establishment of the radiological background of the area. Accordingly, the dismantling and decommissioning process (D&D) of a nuclear power plant starts with a radiological monitoring plan, which includes the radiological characterization of the area and of its surroundings. At the completion of the D&D, unrestricted use for the site will be permitted strictly in accordance with results of the radiological survey within the limits established by the local authorities. Groundwater quality is typically included in any radiological analysis since, among other reasons, a significant part of it is highly likely to end up being extracted for domestic use and hence, human consumption. While there is no regulation containing maximum activity concentration or radionuclide guidance values for water that may be destined for uses other than public consumption, if groundwater is considered a "part" of the land, dose criteria for site release can be applied. Therefore, together with the guidance levels to be established for the different radionuclides expected in the groundwater, the detection limits to be employed when performing routine radio analytical characterization procedures in the laboratory should also be provided. In this paper, we first propose a relation of the potential radionuclides to be analyzed in groundwater, together with their detection limits to be achieved when the determinations are performed in a laboratory, and subsequently, we discuss the most suitable analytical methodologies and resources that would be necessary to undertake radiological characterization plans from a practical point of view.
    Language English
    Publishing date 2023-08-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e19470
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  7. Article ; Online: MYD88 L265P Mutation Detection by ddPCR: Recommendations for Screening and Minimal Residual Disease Monitoring : ddPCR for Highly Sensitive Detection of MYD88 L265P Mutation.

    Drandi, Daniela / Ferrante, Martina / Borriero, Michela / Ferrero, Simone

    Methods in molecular biology (Clifton, N.J.)

    2023  Volume 2621, Page(s) 57–72

    Abstract: ... ...

    Abstract MYD88
    MeSH term(s) Humans ; Myeloid Differentiation Factor 88 ; Neoplasm, Residual ; Prospective Studies ; Mutation ; Polymerase Chain Reaction/methods ; Immunoglobulin M/genetics
    Chemical Substances Myeloid Differentiation Factor 88 ; Immunoglobulin M
    Language English
    Publishing date 2023-04-11
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2950-5_5
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  8. Article ; Online: Endometrial receptivity in women with endometriosis.

    Racca, Annalisa / Bernabeu, Andrea / Bernabeu, Rafael / Ferrero, Simone

    Best practice & research. Clinical obstetrics & gynaecology

    2023  Volume 92, Page(s) 102438

    Abstract: As endometriosis is recognized as a contributing factor to infertility, prompting couples to embark on Assisted Reproductive Technology (ART) treatments, it becomes crucial to comprehend the extent and way this condition can affect success rates. Natural ...

    Abstract As endometriosis is recognized as a contributing factor to infertility, prompting couples to embark on Assisted Reproductive Technology (ART) treatments, it becomes crucial to comprehend the extent and way this condition can affect success rates. Natural conception data reveal lower success rates for women with endometriosis, yet the same cannot be extrapolated to the outcomes of in vitro fertilization (IVF). In recent years, advancements in the ART process, particularly the distinct stages of the IVF pathway and investigations into embryo quality have shown a comparable rate of embryonic quality and chromosomal normalcy (euploidy) between embryos obtained from individuals with or without endometriosis. Thus, the primary question that lingers relates to the functionality of the endometrium. This review addresses whether endometriosis can influence endometrial receptivity and implantation rates.
    MeSH term(s) Humans ; Female ; Pregnancy ; Endometriosis/complications ; Infertility, Female/etiology ; Infertility, Female/therapy ; Embryo Implantation ; Fertilization in Vitro ; Endometrium ; Pregnancy Rate
    Language English
    Publishing date 2023-11-29
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2050090-7
    ISSN 1532-1932 ; 1521-6934
    ISSN (online) 1532-1932
    ISSN 1521-6934
    DOI 10.1016/j.bpobgyn.2023.102438
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  9. Article ; Online: Endometriosis: Modern management of an ancient disease.

    Ferrero, Simone

    European journal of obstetrics, gynecology, and reproductive biology

    2017  Volume 209, Page(s) 1–2

    MeSH term(s) Disease Management ; Endometriosis/therapy ; Female ; Humans ; Pain Management
    Language English
    Publishing date 2017-02
    Publishing country Ireland
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 190605-7
    ISSN 1872-7654 ; 0301-2115 ; 0028-2243
    ISSN (online) 1872-7654
    ISSN 0301-2115 ; 0028-2243
    DOI 10.1016/j.ejogrb.2016.12.036
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  10. Article ; Online: Dichotomic response to interleukin-6 blockade in idiopathic multicentric Castleman disease: two case reports.

    Ferrero, Simone / Ragaini, Simone

    Journal of medical case reports

    2021  Volume 15, Issue 1, Page(s) 105

    Abstract: Background: Human herpervirus-8/human immunodeficiency virus negative Idiopathic multicentric Castleman disease (iMCD) is a lymphoproliferative disorder sustained by a pro-inflammatory condition of hypercytokinemia mostly mediated by Interleukin-6 (IL-6) ...

    Abstract Background: Human herpervirus-8/human immunodeficiency virus negative Idiopathic multicentric Castleman disease (iMCD) is a lymphoproliferative disorder sustained by a pro-inflammatory condition of hypercytokinemia mostly mediated by Interleukin-6 (IL-6). According to iMCD consensus guidelines, anti-IL-6 blockade should be the first-line therapy for iMCD. However, despite the existing therapeutic alternatives, a large proportion of iMCD patients still lacks an effective therapy.
    Case presentation: Here, we report two real-life iMCD cases with a different response to IL-6 blockade. The first presented patient obtained a prompt resolution of symptoms and a complete regression of adenopathies after IL-6 blockade therapy administration. Conversely, the second patient did not respond neither to Rituximab and Etoposide association nor to IL-6 blockade therapy (both Siltuximab and Tocilizumab). Furthermore, Intravenous immunoglobulin, Cyclosporine A, Sirolimus and anti-Interleukin-1 Anakinra were all attempted without any results. Since no treatment was successful, after a further confirmation of iMCD diagnosis by a second lymph node biopsy, patient has been candidate for thalidomide, cyclophosphamide and prednisone association therapy.
    Conclusions: The iMCD cases we reported are coherent with the evidences that IL-6 blockade is a safe and an effective therapy for iMCD. Despite this, more than half of patients do not respond to anti IL-6 drugs. In such cases, therapeutic alternatives could be represented by Sirolimus, targeting PI3K/AKT/mTOR signaling or by associations of conventional drugs such as thalidomide, cyclophosphamide and prednisone. However, the two reported iMCD cases, confirm the need to more deeply investigate iMCD pathogenesis and to better dissect the heterogeneity of the disease in order to develop novel, effective therapeutic strategies.
    MeSH term(s) Castleman Disease/drug therapy ; Humans ; Interleukin 1 Receptor Antagonist Protein ; Interleukin-6 ; Phosphatidylinositol 3-Kinases ; Rituximab
    Chemical Substances Interleukin 1 Receptor Antagonist Protein ; Interleukin-6 ; Rituximab (4F4X42SYQ6)
    Language English
    Publishing date 2021-03-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-021-02726-4
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