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Article: Topoclimate and wine quality: results of research on the Gewürztraminer grape variety in South Tyrol, northern Italy

Ferretti, C.

OENO One

2021 Volume 55, Issue 1, Page(s) 313–335

Abstract: The aim of the study was to identify the ecological indicators that facilitate predictive analysis and to search for patterns in local geographical information to identify risks and opportunities in viticulture. The study focused on environmental factors ...

Institution	GIR - Geo Identity Research, Bolzano, Italy
Abstract	The aim of the study was to identify the ecological indicators that facilitate predictive analysis and to search for patterns in local geographical information to identify risks and opportunities in viticulture. The study focused on environmental factors that significantly affect the ripeness of the Gewürztraminer grape variety cultivated near Tramin, a village in northern Italy. In particular, the reliability of the new Solar Radiation Identity (SRI) topoclimate classification method was tested, along with its predictive capability in terms of the biosynthetic activity of the vine and the quality of its grapes. The SRI index characterises each vineyard in a precise and comparable way and helps to understand the way in which the topoclimate acts as an important abiotic stress factor for vines. A direct relationship between grape must sugar content and the SRI topoclimate index was observed. Our findings indicate an increase in sugar content of approximately 0.8 °KMW for every 10 points of the SRI index. Thus, a novel prediction model of grape ripening based on an SRI curve analysis is proposed. The correct application of the SRI index could be useful for discriminating and predicting geographical charactersitics of a given area, strongly connected to ecological diversity and wine quality. It could support decision making in viticulture in terms of, for example, correctly matching vineyard and grape varieties, reducing wine vulnerability and production risk and predicting optimal ripeness and harvesting days. The use of the SRI prediction curve could help in adopting a more sustainable approach to agriculture and in finding new methods for adapting to climate change, such as by improving the match between the cultivars’ phenological status, vineyard location and growing season average temperature.
Language	English
Document type	Article
ISSN	2494-1271
Database	Viticulture and Oenology Abstracts

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Article ; Online: Pediatric Mandibular Defect Rehabilitation by Human Transforming Growth Factor-β3 with an Implant-Supported Prosthesis.

Ferretti, Carlo / Ripamonti, Ugo

The International journal of oral & maxillofacial implants

2022 Volume 37, Issue 6, Page(s) 1256–1260

Abstract: Large mandibular defects in children are an uncommon but challenging problem for surgeons to solve. The time-honored options of autologous bone grafts are seldom a viable option, as suitable donor sites are unavailable. Osteoinductive morphogens may yet ... ...

Abstract	Large mandibular defects in children are an uncommon but challenging problem for surgeons to solve. The time-honored options of autologous bone grafts are seldom a viable option, as suitable donor sites are unavailable. Osteoinductive morphogens may yet provide a solution in these cases. A large mandibular tumor in a child 10 years of age necessitated the resection of the entire dentate portion of the mandible. The defect was reconstructed at a second stage with a composite graft of human transforming growth factor-β3 (hTGF-β3), human demineralized bone matrix, and 12 g of autologous bone harvested from the posterior iliac crest. A mature ossicle suitable for the placement of osseointegrated implants developed in the erstwhile defect, and an implant-supported dental prosthesis was placed. The patient has been followed up into adulthood. Facial growth has proceeded unhindered, and the patient has maintained full oral and dental function. This case reports the long-term result of an uncommon condition treated with a novel method. The longterm follow-up of this patient provides evidence to dispel some of the concerns for the use of osteoinductive proteins in children. A composite graft of osteogenic morphogens, osteocompetent autologous cells, and mineralized and demineralized matrices-as opposed to osteogenic morphogens used solo-may improve clinical bone regeneration.
MeSH term(s)	Child ; Humans ; Adult ; Dental Implants ; Mandible/surgery ; Bone Transplantation ; Transplantation, Autologous ; Transforming Growth Factors
Chemical Substances	Dental Implants ; Transforming Growth Factors (76057-06-2)
Language	English
Publishing date	2022-10-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	632880-5
ISSN	1942-4434 ; 0882-2786
ISSN (online)	1942-4434
ISSN	0882-2786
DOI	10.11607/jomi.9803
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Zs.A 2179: Show issues

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Article ; Online: Antonio Scarpa (1752-1832): His Contribution to the History of Surgery.

Ferretti, Cecilia / Stroppa, Daniele / Riva, Michele Augusto

Surgical innovation

2023 Volume 30, Issue 5, Page(s) 622–624

Abstract: Background: Antonio Scarpa (1752-1832) is generally remembered for his discoveries in the field of anatomy, but he also provided some important contributions to the history of surgery.: Methods: We analyzed main treatises written by Scarpa, ... ...

Abstract	Background: Antonio Scarpa (1752-1832) is generally remembered for his discoveries in the field of anatomy, but he also provided some important contributions to the history of surgery. Methods: We analyzed main treatises written by Scarpa, highlighting how he contributed to the development of modern surgery. Results: Scarpa made great innovations in three branches of surgery: abdominal surgery (hernia), orthopedics (clubfoot) and vascular surgery (aneurism). Furthermore, he contributed to the birth of modern ophthalmology.
MeSH term(s)	Male ; Humans ; Ophthalmology ; Orthopedic Procedures ; Orthopedics
Language	English
Publishing date	2023-01-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2182571-3
ISSN	1553-3514 ; 1553-3506
ISSN (online)	1553-3514
ISSN	1553-3506
DOI	10.1177/15533506221149774
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Zs.A 4269: Show issues

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Article ; Online: The Conundrum of Human Osteoinduction: Is the Bone Induction Principle Failing Clinical Translation?

Ferretti, Carlo / Ripamonti, Ugo

The Journal of craniofacial surgery

2021 Volume 32, Issue 4, Page(s) 1287–1289

MeSH term(s)	Bone and Bones ; Humans ; Osteogenesis
Language	English
Publishing date	2021-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000007429
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Article: Land suitability of the different cultivars in the South Tyrol wine region (Italy)

Ferretti, C. G.

Agricultural Sciences

2020 Volume 11, Issue 11, Page(s) 983–1006

Abstract: The geology and geomorphology of the territory as well as microclimate are local geographical features that serve as natural ecological resources. These factors influence the biosynthetic activities of plants and their phenology, promoting biodiversity ... ...

Institution	GIR Geo Identity Research, Bolzano, Italy
Abstract	The geology and geomorphology of the territory as well as microclimate are local geographical features that serve as natural ecological resources. These factors influence the biosynthetic activities of plants and their phenology, promoting biodiversity and the qualitative predispositions of grapes and wine. South Tyrol is one of the smallest wine-growing regions in Italy, but owing to its position amid the Alps, it is also one of the most multifaceted, a region of wide geographical diversity and remarkable ecological range, hosting a concentration of many different vine varieties and high quality wines. This applied territorial research investigates the particular environmental circumstances that favour this case. A data set describing approximately 26,000 vineyards and 5450 hectares has been employed to evaluate 18 subzones of wines and vines selected from 86 new geographical units defined within the DOC wine region. A new environmental mapping scheme called VHTG is proposed, based on the ecological indicators of grape variety, altitude, topoclimate and the geopedology of the vineyards. Using the VHTG method analyses, the comparisons between the territories of origin and their vine varieties can be rendered simpler and more direct, and it can distinguish the most suitable ecological conditions of wine production zones. It is now possible to examine more in detail the land suitability of the different cultivars, defined by the use of the ecological indicators summarized in the VHTG method. White grape varieties such as Sylvaner and Veltliner prefer high altitudes between 600 m and 900 m, a very high solar radiation SRI index from 80 to 95, and acidic sandy soils of silicate minerals. The most complete and intense tannic structure of regional Pinot Noir correlates to quite clayey soils with dolomite mineral, slightly alkaline, on vineyards at altitudes between 350 m and 410 m, with rather low SRI index from 60 to 75. Similar geopedological conditions favour Gewürztraminer, which, however, requests SRI from 75 to 85. Merlot and Cabernet vines are best expressed in the hottest regional sub-zones, on moderately clayey subalkaline soils at 250 - 350 m of altitudes and SRI around 80. The indigenous red grape variety Lagrein is mostly localized on alluvial cone at altitudes under 350 m, on soft and ventilated acid sands with volcanic silicate minerals.
Language	English
Document type	Article
ZDB-ID	2591052-8
ISSN	2156-8561 ; 2156-8553
ISSN (online)	2156-8561
ISSN	2156-8553
DOI	10.4236/as.2020.1111064
Database	Viticulture and Oenology Abstracts

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Article: A new geographical classification for vineyards tested in the South Tyrol wine region, northern Italy, on Pinot Noir and Sauvignon Blanc wines

Ferretti, C. G.

Ecological Indicators

2020 Volume 108, Issue Art. 105737, Page(s) 17 pp.

Abstract: Solar Radiation Identity (SRI); topoclimate; Vineyard Geographical Identity (VGI); Pinot Noir/Sauvignon Blanc wine quality; terroir; Alto Adige-Südtirol DOC. ...

Institution	Professional Geologist and Researcher, GIR Geo Identity Research, South Tyrol, Italy
Abstract	Solar Radiation Identity (SRI); topoclimate; Vineyard Geographical Identity (VGI); Pinot Noir/Sauvignon Blanc wine quality; terroir; Alto Adige-Südtirol DOC.
Language	English
Document type	Article
ISSN	1470-160X
Database	Viticulture and Oenology Abstracts

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Article ; Online: Evaluation of two commercial broth microdilution systems for dalbavancin susceptibility testing of methicillin-resistant Staphylococcus aureus and other resistant Gram-positive cocci.

Baccani, Ilaria / Antonelli, Alberto / Cuffari, Sara / Ferretti, Caterina / Giani, Tommaso / Rossolini, Gian Maria

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

2024

Abstract: Objectives: This study aims to evaluate two commercial broth microdilution (BMD) systems, E1-185-100 (Merlin) and FDANDPF (ThermoFisher), for dalbavancin susceptibility testing in comparison with reference BMD assay.: Methods: Study collection was ... ...

Abstract	Objectives: This study aims to evaluate two commercial broth microdilution (BMD) systems, E1-185-100 (Merlin) and FDANDPF (ThermoFisher), for dalbavancin susceptibility testing in comparison with reference BMD assay. Methods: Study collection was composed of 200 non-replicate multidrug-resistant Gram-positive cocci of clinical origin, including 180 methicillin-resistant Staphylococcus aureus, 10 vancomycin-resistant enterococci, seven linezolid-resistant Staphylococcus epidermidis, and three methicillin-resistant coagulase-negative staphylococci. S. aureus ATCC 29213 and Enterococcus faecalis ATCC 29212 reference strains were also included as controls. Testing was performed according to the ISO 20776-1 standard, starting from the same bacterial inoculum, and results were compared according to the ISO 20776-2 standard. Results: Reference BMD showed that 92.6% (187/202) of the strains were susceptible to dalbavancin, whereas few staphylococci and all VanA-producing enterococci showed a resistant phenotype. In comparison with the reference method, Category Agreement and Essential Agreement were 98% (198/202; 95% CI, 95.4-99.3%) and 98% (198/202; 95% CI, 95.4-99.3%) for both Merlin and ThermoFisher panels. A few false susceptibilities were observed, for both commercial systems, with dalbavancin-resistant staphylococci. BIAS values of 11% and 3% were calculated for the Merlin and ThermoFisher systems, respectively. Discussion: This study, reporting the first evaluation of the two commercially available BMD assays for dalbavancin susceptibility testing, revealed an overall good correlation with reference BMD, although with some underestimation tendency of MIC values by both commercial systems. Further studies involving a higher number of resistant isolates will be necessary to better evaluate this issue.
Language	English
Publishing date	2024-03-15
Publishing country	England
Document type	Journal Article
ZDB-ID	1328418-6
ISSN	1469-0691 ; 1470-9465 ; 1198-743X
ISSN (online)	1469-0691
ISSN	1470-9465 ; 1198-743X
DOI	10.1016/j.cmi.2024.03.013
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Zs.A 4541: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 284: Show issues

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Article ; Online: A mass guide for the harvest of cortico-cancellous bone from the posterior iliac crest for mandibular reconstruction.

Ferretti, C / Premviyasa, V / Reyneke, J / Ripamonti, U

The British journal of oral & maxillofacial surgery

2019 Volume 57, Issue 7, Page(s) 627–631

Abstract: This study sought to find the mass of particulate cortico-cancellous bone graft required per 1 cm continuity defect of the mandible. Harvested bone was weighed, milled and maximally compressed in a syringe. The defect length (DL) was measured in ... ...

Abstract	This study sought to find the mass of particulate cortico-cancellous bone graft required per 1 cm continuity defect of the mandible. Harvested bone was weighed, milled and maximally compressed in a syringe. The defect length (DL) was measured in centimetres, and the compressed bone volume (CBV) used was recorded. The wet bone mass (WBM) of bone required per centimetre of mandibular defect, and the mass of bone yielding 1cc of compressed bone was calculated. Results were analysed statistically to determine if clinically meaningful differences exist between male and female iliac crest. Forty three patient records were reviewed (28 female). Thirty patients had bilateral, and 13 patients had unilateral iliac crest harvest. Mean WBM used per centimetre of mandible defect was 6.9 g.WBM required to produce 1cc of CBV was 2.0g. For the bilateral harvest group the mean DL was 10.3 cm, the mean WBM was 66.7 g, and the mean CBV was 33.9cc. There was no significant difference in mean WBM between male (72.8 g) and female (62 g) patients. The mean CBV for males (39.7 g) was significantly higher than females (29.5 g). For patients who had unilateral harvest the mean DL was 7.7 cm, the mean WBM harvested was 59.1 g, and the mean CBV was 29.4cc. The mean wet bone mass of posterior iliac crest required to graft each centimetre of mandibular segmental defect is 6.9 grams. A unilateral posterior iliac crest harvest will yield on average 59.1 grams of bone whilst a bilateral posterior iliac crest harvest will yield on average 66.7 grams.
MeSH term(s)	Bone Transplantation ; Cancellous Bone ; Female ; Humans ; Ilium/diagnostic imaging ; Imaging, Three-Dimensional ; Male ; Mandible ; Mandibular Reconstruction/methods ; Retrospective Studies ; Tomography, X-Ray Computed
Language	English
Publishing date	2019-06-14
Publishing country	Scotland
Document type	Journal Article ; Observational Study
ZDB-ID	605685-4
ISSN	1532-1940 ; 0266-4356
ISSN (online)	1532-1940
ISSN	0266-4356
DOI	10.1016/j.bjoms.2019.04.012
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Article: Le cas clinique du mois. Œdème aigu du poumon et traitement par tocolytiques chez la femme enceinte.

Hardy, P Y / Depierreux, F / Ferretti, C

Revue medicale de Liege

2019 Volume 74, Issue 3, Page(s) 129–133

Abstract: We report the case of a pregnant woman, treated by nifedipine and next by atosiban for premature labour, who develop an acute pulmonary edema. The severity of symptoms and hypoxemia lead the patient to a cesarean and next to the intensive care ... ...

Title translation	Acute pulmonary edema and tocolytic therapy in pregnant women : clinical case and review of literature.
Abstract	We report the case of a pregnant woman, treated by nifedipine and next by atosiban for premature labour, who develop an acute pulmonary edema. The severity of symptoms and hypoxemia lead the patient to a cesarean and next to the intensive care hospitalization. This clinical case allow us to make a review of literature and reminds us the differential diagnosis to look for during an acute dyspnea in a pregnant woman and the treatment of acute pulmonary edema in these circumstances. The pathophysiological mechanisms which are at the origins of this condition and the implication of the tocolytic treatment will also be discussed.
MeSH term(s)	Diagnosis, Differential ; Female ; Humans ; Obstetric Labor, Premature/drug therapy ; Pregnancy ; Pulmonary Edema/chemically induced ; Tocolysis ; Tocolytic Agents/adverse effects ; Tocolytic Agents/therapeutic use
Chemical Substances	Tocolytic Agents
Language	French
Publishing date	2019-03-21
Publishing country	Belgium
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	414001-1
ISSN	0370-629X ; 0035-3663
ISSN	0370-629X ; 0035-3663
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Zs.A 597: Show issues

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Article ; Online: Long Term Follow-Up of Pediatric Mandibular Reconstruction With Human Transforming Growth Factor-β3.

Ferretti, Carlo / Ripamonti, Ugo

The Journal of craniofacial surgery

2020 Volume 31, Issue 5, Page(s) 1424–1429

Abstract: Translating bone regeneration induced by recombinant human bone morphogenetic proteins from animal models to human patients has proven inexplicably inconsistent. This prompted us to test in 5 pediatric patients, an alternative osteoinductive morphogen, ... ...

Abstract	Translating bone regeneration induced by recombinant human bone morphogenetic proteins from animal models to human patients has proven inexplicably inconsistent. This prompted us to test in 5 pediatric patients, an alternative osteoinductive morphogen, recombinant human transforming growth factor β3 (hTGF-β3), to reconstruct mandibular defects of such a size to preclude reconstruction with autologous bone. An osteoinductive implant of human demineralized bone matrix (DBM) loaded with 125 μg hTGF-β3 per gram of DBM was implanted into one defect, and 250 μg hTGF-β3 per gram of DBM in another. Thereafter in 3 patients limited amounts of particulate cortico-cancellous bone graft harvested from the posterior iliac crest were combined with 250 μg hTGF-β3 per gram of DBM. Patients were followed up for 3 to 6 years. Three patients achieved clinically significant osteoinduction, 1 patient with hTGF-β3 only, and 2 by combining hTGF-β3 with a small supplement of autologous bone. One patient with hTGF-β3 only and followed up for 5 years retains a viable reconstruction but has had sub-optimal bone regeneration. One patient had osteoinductive failure due to sepsis although the plate reconstruction remains viable. Recombinant human TGF-β3 initiates osteoinduction in humans and potentiates autologous bone graft activity allowing the reconstruction of large mandibular defects in pediatric patients.
MeSH term(s)	Adolescent ; Bone Regeneration/drug effects ; Child ; Female ; Follow-Up Studies ; Humans ; Male ; Mandibular Reconstruction ; Recombinant Proteins/therapeutic use ; Time Factors ; Transforming Growth Factor beta3/therapeutic use
Chemical Substances	Recombinant Proteins ; TGFB3 protein, human ; Transforming Growth Factor beta3
Language	English
Publishing date	2020-06-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1159501-2
ISSN	1536-3732 ; 1049-2275
ISSN (online)	1536-3732
ISSN	1049-2275
DOI	10.1097/SCS.0000000000006568
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Zs.MO 175: Show issues

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