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  1. Article ; Online: Gamification as a Tool for Promoting Physical Exercise and Healthy Eating Habits in Healthcare Worker Women: Effects on Cardiometabolic Health and Physical Fitness at Workplace.

    Gimenez, Lucas B / Teixeira do Amaral, Vanessa / Locato, Gabriel / Marçal, Isabela R / Ferron, Artur J T / Ciolac, Emmanuel G

    American journal of health promotion : AJHP

    2024  , Page(s) 8901171241234664

    Abstract: Purpose: To evaluate the effectiveness of gamified versus nongamified health promotion interventions on cardiometabolic health and fitness parameters in healthcare worker women.: Design: Randomized parallel group trial.: Setting: A public ... ...

    Abstract Purpose: To evaluate the effectiveness of gamified versus nongamified health promotion interventions on cardiometabolic health and fitness parameters in healthcare worker women.
    Design: Randomized parallel group trial.
    Setting: A public outpatient health center in Brazil.
    Subjects: Women employees (included: n = 29; lost to follow-up: n = 1; analyzed: n = 28).
    Interventions: 8 weeks of gamified (n = 15) or nongamified (n = 13) interventions, consisting of health lectures, nutritional counseling, and supervised exercise training. The gamified group was divided into teams that received points based on completion of health goals/tasks.
    Measures: Anthropometric, cardiometabolic and physical fitness parameters.
    Analysis: Two-way ANOVA with repeated measures (group vs. time), and Bonferroni
    Results: Body mass (-1.5 ± 1.5 kg), waist circumference (-1.6 ± 3.0 cm), HbA1C (-.2 ± .3%), triglycerides (-21.5 ± 48.2 mg/dl), systolic (-11.1 ± 7.9 mmHg) and diastolic (-7.1 ± 5.8 mmHg) blood pressure, as well as sit and reach (3.9 ± 3.0 cm) and six-minute walking (56 ± 37 m) performance improved (
    Conclusion: The gamified intervention was more effective than the nongamified intervention for improving cardiometabolic and physical fitness parameters, suggesting that gamification may be an effective tool for promoting health in healthcare worker women.
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645160-3
    ISSN 2168-6602 ; 0890-1171
    ISSN (online) 2168-6602
    ISSN 0890-1171
    DOI 10.1177/08901171241234664
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Differentially expressed proteins obtained by label-free quantitative proteomic analysis reveal affected biological processes and functions in Western diet-induced steatohepatitis.

    Moreto, Fernando / Ferron, Artur J T / Francisqueti-Ferron, Fabiane V / D'Amato, Alfonsina / Garcia, Jessica L / Costa, Mariane R / Silva, Carol Cristina V A / Altomare, Alessandra / Correa, Camila Renata / Aldini, Giancarlo / Ferreira, Ana Lucia A

    Journal of biochemical and molecular toxicology

    2021  Volume 35, Issue 6, Page(s) 1–11

    Abstract: Nonalcoholic steatohepatitis (NASH) is a pathological manifestation with a progressive incidence in response to the epidemic of hepatic steatosis caused primarily by excessive energy intake. The present study unravels affected biological processes and ... ...

    Abstract Nonalcoholic steatohepatitis (NASH) is a pathological manifestation with a progressive incidence in response to the epidemic of hepatic steatosis caused primarily by excessive energy intake. The present study unravels affected biological processes and functions by the presence of NASH in rats using a label-free quantitative proteomic strategy. NASH was induced by a Western high-sugar and high-fat diet for 20 weeks. The liver tissue was collected for histology and for a mass spectrometry-based proteomic protocol. The NASH group showed severe lipidosis, hepatocyte ballooning, and the presence of collagen deposition. Among upregulated proteins in NASH perilipin-2 (Plin-2; F6QBA3; difference [diff]: 2.29), ferritin heavy (Fth1; Q66HI5; diff: 2.19) and light (Ftl1; P02793; diff: 1.75) chains, macrophage migration inhibitory factor 1 (Mif; P30904; diff: 1.69), and fibronectin (Fn1; F1LST1; diff: 0.35) were observed, whereas among downregulated proteins, plectin (Q6S399; diff: -3.34), some Cyp2 family proteins of the cytochrome P450 complex, glutathione S-transferases, flavin-containing monooxygenase 1 (Fmo1; P36365; diff: -2.08), acetyl-CoA acetyltransferase 2 (Acat2; Q5XI22; diff: -2.25), acyl-CoA oxidase 2 (Acox2; F1LNW3; diff: -1.59), and acyl-CoA oxidase 3 (Acox3; F1M9A7; diff: -2.41) were observed. Also, biological processes and functions such as LPS/IL-1 inhibition of RXR, fatty acid metabolism, Nrf2-mediated oxidative stress response, xenobiotic metabolism, and PXR/RXR and CAR/RXR activations were predicted to be affected. In conclusion, the liver of rats with NASH induced by Western diet shows a decreased capacity of metabolizing lipids, fatty acids, and xenobiotic compounds that predispose fibrosis development.
    Language English
    Publishing date 2021-03-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1410020-4
    ISSN 1099-0461 ; 1095-6670
    ISSN (online) 1099-0461
    ISSN 1095-6670
    DOI 10.1002/jbt.22751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hydroethanolic Extract of

    Ferraz, Ana Paula C R / Sussulini, Alessandra / Garcia, Jéssica L / Costa, Mariane R / Francisqueti-Ferron, Fabiane V / Ferron, Artur J T / Silva, Carol Cristina V de A / Corrente, José Eduardo / Manfio, Vanessa M / Namba, Vickeline / Lima, Giuseppina P P / Pereira, Bismarque S / Fecchio, Denise / Minatel, Igor O / Dos Santos, Klinsmann C / Corrêa, Camila R

    Oxidative medicine and cellular longevity

    2020  Volume 2020, Page(s) 7240216

    Abstract: ... Solanum ... ...

    Abstract Solanum paniculatum
    MeSH term(s) Carotenoids/analysis ; Cell Line ; Cell Survival/drug effects ; Cytokines/metabolism ; Ethanol/chemistry ; Fruit/chemistry ; Humans ; Plant Extracts/pharmacology ; Reactive Oxygen Species/metabolism ; Solanum/chemistry ; Water/chemistry
    Chemical Substances Cytokines ; Plant Extracts ; Reactive Oxygen Species ; Water (059QF0KO0R) ; Carotenoids (36-88-4) ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2020-01-22
    Publishing country United States
    Document type Journal Article
    ISSN 1942-0994
    ISSN (online) 1942-0994
    DOI 10.1155/2020/7240216
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Moderate exercise training does not prevent the reduction in myocardial L-type Ca

    da Silva, Vitor L / Lima-Leopoldo, Ana P / Ferron, Artur J T / Cordeiro, Jóctan P / Freire, Paula P / de Campos, Dijon H S / Padovani, Carlos R / Sugizaki, Mário M / Cicogna, Antonio C / Leopoldo, André S

    Physiological reports

    2017  Volume 5, Issue 19

    Abstract: Authors have showed that obesity implicates cardiac dysfunction associated with myocardial L-type calcium channels (LTCCs) activity impairments, as well as moderate exercise training (MET) seems to be an important therapeutic tool. We tested the ... ...

    Abstract Authors have showed that obesity implicates cardiac dysfunction associated with myocardial L-type calcium channels (LTCCs) activity impairments, as well as moderate exercise training (MET) seems to be an important therapeutic tool. We tested the hypothesis that MET promotes improvements on LTCCS activity and protein expression at obesity induced by unsaturated high-fat diets, which could represent a protective effects against development of cardiovascular damage. Male
    MeSH term(s) Animals ; Calcium Channels, L-Type/genetics ; Calcium Channels, L-Type/metabolism ; Diet, High-Fat/adverse effects ; Male ; Motor Activity ; Myocardium/metabolism ; Obesity/etiology ; Obesity/metabolism ; Obesity/pathology ; Physical Conditioning, Animal/methods ; Rats ; Rats, Wistar ; Ventricular Remodeling
    Chemical Substances Calcium Channels, L-Type
    Language English
    Publishing date 2017-10-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2724325-4
    ISSN 2051-817X ; 2051-817X
    ISSN (online) 2051-817X
    ISSN 2051-817X
    DOI 10.14814/phy2.13466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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