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Article ; Online: Life-Threatening Wunderlich Syndrome Associated with Apixaban and the Complexity of Anticoagulation Management in Bleeding Patients

Sérgio Maltês / Cristina Carvalho Gouveia / Filipa Serrazina / Marta Rebelo

Acta Médica Portuguesa, Vol 36, Iss 3, Pp 206-

A Case Report

2022  Volume 209

Abstract: Wunderlich syndrome is a rare and possibly life-threatening haemorrhagic syndrome presenting as spontaneous nontraumatic renal rupture with subcapsular and perinephric haemorrhage. Apixaban, a direct oral anticoagulant recommended in patients with atrial ...

Abstract Wunderlich syndrome is a rare and possibly life-threatening haemorrhagic syndrome presenting as spontaneous nontraumatic renal rupture with subcapsular and perinephric haemorrhage. Apixaban, a direct oral anticoagulant recommended in patients with atrial fibrillation, has previously been associated with atraumatic solid organ rupture but, to date, no case of apixaban-related Wunderlich syndrome has been reported. We report a rare case of Wunderlich syndrome associated with apixaban while addressing the difficulties face by clinicians when managing anticoagulation in bleeding patients.
Keywords acute kidney injury ; anticoagulants/adverse effects ; hemorrage ; kidney diseases/chemically induced ; rupture ; spontaneous ; Medicine ; R ; Medicine (General) ; R5-920
Language English
Publishing date 2022-07-01T00:00:00Z
Publisher Ordem dos Médicos
Document type Article ; Online
Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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