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  1. AU="Filiponi, Thiago Corsi"
  2. AU="Specht, Rachel"
  3. AU="Cavazza, Christine"
  4. AU="Hoffman, Judy"
  5. AU="Schubert, Dirk"
  6. AU=Jia Xiao-yu
  7. AU="Patra, Dhabaleswar"
  8. AU="Knill, Carly"
  9. AU=Jabbour Elias
  10. AU="Rodríguez-Maresca, Manuel Ángel"
  11. AU="Yang, Chang-Jung"
  12. AU="Atul Kaushik"
  13. AU="Peters, Jaime"
  14. AU="Dorothee von Laer"
  15. AU="Sreeja Attur"
  16. AU=Song Kyung Chul
  17. AU=Klimovich Pavel V.
  18. AU="Jingbo Chen"
  19. AU="Viazlo, Oleksander"
  20. AU="Toshiki Iwabuchi"
  21. AU="Dissanayake, Lakmali"
  22. AU="Michael Denkinger"
  23. AU="Abilio J. F. N. Sobral"
  24. AU="Geller, Alan"
  25. AU=Petrat Sren
  26. AU="Sterling, Shanique"
  27. AU="Qi, Zeqiang"
  28. AU="Thongstisubskul, A"
  29. AU="Daniel C. Schneider, PhD"
  30. AU="Völker, Christoph"
  31. AU="El Aoud, S"
  32. AU="Yi, Tongpei"
  33. AU="Anil K. Mantha"
  34. AU="Artzner, Christoph"
  35. AU=Diana Giovanni
  36. AU="Kinloch, Sabine"
  37. AU="Nuertey, David"
  38. AU="Ojubolamo, Olakunle"

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  1. Artikel ; Online: How to choose the ideal renal replacement therapy in sepsis?

    Filiponi, Thiago Corsi / de Souza Durão, Marcelino

    Shock (Augusta, Ga.)

    2013  Band 39 Suppl 1, Seite(n) 50–53

    Abstract: Sepsis is the main cause of acute kidney injury (AKI) among individuals hospitalized in intensive care units. Acute kidney injury is an independent risk factor for mortality, and its occurrence increases the complexity and cost of treatment. However, the ...

    Abstract Sepsis is the main cause of acute kidney injury (AKI) among individuals hospitalized in intensive care units. Acute kidney injury is an independent risk factor for mortality, and its occurrence increases the complexity and cost of treatment. However, the pathophysiological mechanisms of AKI remain unclear. Hemodynamic, vascular, tubular, cellular, inflammatory, and oxidative processes are involved. Individuals with AKI generally have various comorbidities and are elderly and hypercatabolic and on vasopressors and mechanical ventilation. Dialysis is the main treatment for AKI. Although there is no clear benefit of any specific dialysis modality, these patients are initially instructed to use continuous dialysis methods, especially for the most severe cases with multiple organ system dysfunctions and for those who display signs of hemodynamic instability. Recent studies demonstrate that patients should receive a dialysis dose of at least 25 mL · kg · h.
    Mesh-Begriff(e) Acute Kidney Injury/therapy ; Humans ; Renal Replacement Therapy/methods ; Sepsis/therapy
    Sprache Englisch
    Erscheinungsdatum 2013-05
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1185432-7
    ISSN 1540-0514 ; 1073-2322
    ISSN (online) 1540-0514
    ISSN 1073-2322
    DOI 10.1097/SHK.0b013e31828fafa6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Hospital Admission following Acute Kidney Injury in Kidney Transplant Recipients Is Associated with a Negative Impact on Graft Function after 1-Year.

    Filiponi, Thiago Corsi / Requião-Moura, Lúcio Roberto / Tonato, Eduardo José / Carvalho de Matos, Ana Cristina / E Silva-Filho, Alvaro Pacheco / de Souza Durão Junior, Marcelino

    PloS one

    2015  Band 10, Heft 9, Seite(n) e0138944

    Abstract: The incidence and outcomes of acute kidney injury (AKI) in kidney transplantation are poorly known. Retrospective cohort analysis was performed on the data of all patients (≥3 months after transplantation and ≥16 years of age) admitted to the hospital ... ...

    Abstract The incidence and outcomes of acute kidney injury (AKI) in kidney transplantation are poorly known. Retrospective cohort analysis was performed on the data of all patients (≥3 months after transplantation and ≥16 years of age) admitted to the hospital due to medical or surgical complications from 2007 to 2010. We analyzed 458 kidney transplant recipients, 55.2% men, median age 49 (IQR, 36-58) years, median of 12.5 (IQR, 3-35) months after kidney transplantation; admitted to the hospital due to medical or surgical complications. Most of the patients received a kidney from a deceased donor (62.2%), the primary cause for hospital admission was infection (60.7%) and 57 (12.4%) individuals were diagnosed with acute rejection (AR). The incidence of AKI was 82.3%: 31.9% stage 1, 29.3% stage 2 and 21.2% stage 3. Intensive care unit (ICU) admission (OR 8.90, 95% CI: 1.77-44.56 p = 0.008), infection (OR 5.73, 95% CI: 2.61-12.56, p<0.001) and the use of contrast media (OR 9.34, 95% CI: 2.04-42.70, p = 0.004) were the independent risk factors for AKI development. The mortality rate was 2.1% and all patients who died were diagnosed with AKI. Even after the exclusion of AR cases, at the end of 12 months, the individuals with AKI exhibited higher percent changes in creatinine values when compared with individuals without AKI (9.1% vs. -4.3%; p<0.001). According to KDIGO system, we found a high incidence of AKI among the complications of renal transplantation. As in other scenarios, AKI was associated with renal function loss at 1-year after the hospital discharge.
    Mesh-Begriff(e) Acute Kidney Injury/epidemiology ; Acute Kidney Injury/etiology ; Acute Kidney Injury/mortality ; Adult ; Brazil/epidemiology ; Female ; Graft Rejection/epidemiology ; Graft Rejection/etiology ; Graft Rejection/mortality ; Graft Survival ; Hospitalization/statistics & numerical data ; Humans ; Incidence ; Kidney Transplantation/adverse effects ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Risk Factors ; Survival Rate ; Transplant Recipients/statistics & numerical data
    Sprache Englisch
    Erscheinungsdatum 2015-09-29
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0138944
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Expanding the pool of kidney donors: use of kidneys with acute renal dysfunction.

    Matos, Ana Cristina Carvalho de / Requião-Moura, Lúcio Roberto / Clarizia, Gabriela / Durão Junior, Marcelino de Souza / Tonato, Eduardo José / Chinen, Rogério / Arruda, Érika Ferraz de / Filiponi, Thiago Corsi / Pires, Luciana Mello de Mello Barros / Bertocchi, Ana Paula Fernandes / Pacheco-Silva, Alvaro

    Einstein (Sao Paulo, Brazil)

    2015  Band 13, Heft 2, Seite(n) 319–325

    Abstract: Given the shortage of organs transplantation, some strategies have been adopted by the transplant community to increase the supply of organs. One strategy is the use of expanded criteria for donors, that is, donors aged >60 years or 50 and 59 years, and ... ...

    Abstract Given the shortage of organs transplantation, some strategies have been adopted by the transplant community to increase the supply of organs. One strategy is the use of expanded criteria for donors, that is, donors aged >60 years or 50 and 59 years, and meeting two or more of the following criteria: history of hypertension, terminal serum creatinine >1.5mg/dL, and stroke as the donor´s cause of death. In this review, emphasis was placed on the use of donors with acute renal failure, a condition considered by many as a contraindication for organ acceptance and therefore one of the main causes for kidney discard. Since these are well-selected donors and with no chronic diseases, such as hypertension, renal disease, or diabetes, many studies showed that the use of donors with acute renal failure should be encouraged, because, in general, acute renal dysfunction is reversible. Although most studies demonstrated these grafts have more delayed function, the results of graft and patient survival after transplant are very similar to those with the use of standard donors. Clinical and morphological findings of donors, the use of machine perfusion, and analysis of its parameters, especially intrarenal resistance, are important tools to support decision-making when considering the supply of organs with renal dysfunction.
    Mesh-Begriff(e) Acute Kidney Injury/surgery ; Age Factors ; Aged ; Creatinine/blood ; Delayed Graft Function/mortality ; Donor Selection/organization & administration ; Graft Survival/physiology ; Humans ; Kidney Failure, Chronic/mortality ; Kidney Failure, Chronic/surgery ; Kidney Transplantation/methods ; Kidney Transplantation/mortality ; Length of Stay/statistics & numerical data ; Middle Aged ; Patient Selection ; Survival Rate ; Tissue Donors/supply & distribution
    Chemische Substanzen Creatinine (AYI8EX34EU)
    Sprache Portugiesisch
    Erscheinungsdatum 2015-04
    Erscheinungsland Brazil
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2418293-X
    ISSN 2317-6385 ; 1679-4508
    ISSN (online) 2317-6385
    ISSN 1679-4508
    DOI 10.1590/S1679-45082015RW3147
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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