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  1. Article ; Online: Endoscopic characterization of rectal neuroendocrine tumors with virtual chromoendoscopy: differences between benign and malignant lesions.

    Veyre, Florian / Lambin, Thomas / Fine, Caroline / Fenouil, Tanguy / Rostain, Florian / Walter, Thomas / Pioche, Mathieu

    Endoscopy

    2020  Volume 53, Issue 6, Page(s) E215–E216

    MeSH term(s) Endoscopy ; Humans ; Neuroendocrine Tumors/diagnostic imaging ; Rectal Neoplasms/diagnostic imaging ; Retrospective Studies
    Language English
    Publishing date 2020-09-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1244-9526
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 162: Show issues

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  2. Article: Post first-line dacarbazine or temozolomide in neuroendocrine carcinoma.

    Couronne, Thomas / Girot, Paul / Hadoux, Julien / Lecomte, Thierry / Durand, Alice / Fine, Caroline / Vandevoorde, Katia / Lombard-Bohas, Catherine / Walter, Thomas

    Endocrine connections

    2020  Volume 9, Issue 6, Page(s) 498–505

    Abstract: Objective: First-line chemotherapy in metastatic neuroendocrine carcinomas (NECs) is based on etoposide and platinum. However, there is no standard concerning second-line treatment. The objective of this study was to evaluate efficacy and tolerance of ... ...

    Abstract Objective: First-line chemotherapy in metastatic neuroendocrine carcinomas (NECs) is based on etoposide and platinum. However, there is no standard concerning second-line treatment. The objective of this study was to evaluate efficacy and tolerance of dacarbazine or temozolomide in metastatic digestive NEC as post first-line treatment.
    Material and methods: This study included patients with a metastatic NEC of digestive or unknown primary site. All patients received platinum-etoposide as first-line chemotherapy. Primary endpoint was progression-free survival (PFS). Secondary endpoints were clinical/morphological responses, toxicity, and overall survival (OS).
    Results: Twenty-seven patients were included: 17 received dacarbazine and 10 temozolomide as post-first line treatments. Median PFS was 3.0 (95%CI (2.2;3.7)) months. There was no significant difference between dacarbazine and temozolomide on PFS. Clinical and morphological responses were found in 12 and 9 patients, respectively. Median OS was 7.2 (95%CI (2.2;12.2)) months. The toxicity profile was that expected with such treatments.
    Conclusion: LV5FU2-dacarbazine or temozolomide-capecitabine chemotherapies allow a temporary clinical response for almost half of patients and/or a morphological response for a third of patients.
    Language English
    Publishing date 2020-03-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2668428-7
    ISSN 2049-3614
    ISSN 2049-3614
    DOI 10.1530/EC-20-0192
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Endoscopic characterization of rectal neuroendocrine tumors with virtual chromoendoscopy: differences between benign and malignant lesions

    Veyre, Florian / Lambin, Thomas / Fine, Caroline / Fenouil, Tanguy / Rostain, Florian / Walter, Thomas / Pioche, Mathieu

    Endoscopy

    2020  Volume 53, Issue 06, Page(s) E215–E216

    Language English
    Publishing date 2020-09-11
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1244-9526
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 162: Show issues

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  4. Article ; Online: Systematic Resection of the Visible Scar After Incomplete Endoscopic Resection of Rectal Neuroendocrine Tumors.

    Cheminel, Loïc / Lupu, Alexandru / Wallenhorst, Timothée / Lepilliez, Vincent / Leblanc, Sarah / Albouys, Jérémie / Abou Ali, Einas / Barret, Maximilien / Lorenzo, Diane / De Mestier, Louis / Burtin, Pascal / Girot, Paul / Le Baleur, Yann / Gerard, Romain / Yzet, Clara / Tchirikhtchian, Karl / Degand, Thibault / Culetto, Adrian / Lemmers, Arnaud /
    Schaefer, Marion / Chevaux, Jean-Baptiste / Zhong, Peng / Hervieu, Valérie / Subtil, Fabien / Rivory, Jérôme / Fine, Caroline / Jacques, Jérémie / Walter, Thomas / Pioche, Mathieu

    The American journal of gastroenterology

    2023  Volume 119, Issue 2, Page(s) 378–381

    Abstract: Introduction: When initial resection of rectal neuroendocrine tumors (r-NETs) is not R0, persistence of local residue could lead to disease recurrence. This study aimed to evaluate the interest of systematic resection of non-R0 r-NET scars.: Methods: ...

    Abstract Introduction: When initial resection of rectal neuroendocrine tumors (r-NETs) is not R0, persistence of local residue could lead to disease recurrence. This study aimed to evaluate the interest of systematic resection of non-R0 r-NET scars.
    Methods: Retrospective analysis of all the consecutive endoscopic revisions and resections of the scar after non-R0 resections of r-NETs.
    Results: A total of 100 patients were included. Salvage endoscopic procedure using endoscopic submucosal dissection or endoscopic full-thickness resection showed an R0 rate of near 100%. Residual r-NET was found in 43% of cases.
    Discussion: In case of non-R0 resected r-NET, systematic scar resection by endoscopic full-thickness resection or endoscopic submucosal dissection seems necessary.
    MeSH term(s) Humans ; Neuroendocrine Tumors/surgery ; Cicatrix/etiology ; Cicatrix/pathology ; Retrospective Studies ; Treatment Outcome ; Neoplasm Recurrence, Local/surgery ; Rectal Neoplasms/surgery ; Rectal Neoplasms/pathology ; Endoscopic Mucosal Resection/methods
    Language English
    Publishing date 2023-10-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000002516
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Endoscopic, transanal, laparoscopic, and transabdominal management of rectal neuroendocrine tumors.

    de Mestier, Louis / Lorenzo, Diane / Fine, Caroline / Cros, Jérôme / Hentic, Olivia / Walter, Thomas / Panis, Yves / Couvelard, Anne / Cadiot, Guillaume / Ruszniewski, Philippe

    Best practice & research. Clinical endocrinology & metabolism

    2019  Volume 33, Issue 5, Page(s) 101293

    Abstract: Rectal neuroendocrine tumors (RNET) are rare tumors but their prevalence is constantly increasing due to a prolonged survival and rising incidence related to a growing number of colonoscopies and improved knowledge. Their main prognostic determinant is ... ...

    Abstract Rectal neuroendocrine tumors (RNET) are rare tumors but their prevalence is constantly increasing due to a prolonged survival and rising incidence related to a growing number of colonoscopies and improved knowledge. Their main prognostic determinant is tumor stage. While most RNET are localized, their management should be tailored depending on the presence or absence of the factors predictive of lymph-node metastases including tumor size, endoscopic aspect, T stage, grade and lymphovascular invasion. Endoscopic ultrasonography is the most relevant technique for locoregional assessment. Low-risk RNET can be treated using advanced endoscopic resection techniques or transanal endoscopic microsurgery, in expert centers because they require technicity and experience. Conversely, radical surgery with lymphadenectomy should be proposed in the presence of any pejorative factor. The long-term evolution of RNET remains to be specified, and prospective studies should be conducted in order to determine the relevance of the current management strategies.
    MeSH term(s) Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Laparoscopy/standards ; Neuroendocrine Tumors/surgery ; Postoperative Complications/epidemiology ; Practice Guidelines as Topic ; Rectal Neoplasms/surgery ; Transanal Endoscopic Surgery/adverse effects ; Transanal Endoscopic Surgery/methods ; Transanal Endoscopic Surgery/standards
    Language English
    Publishing date 2019-07-09
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2052339-7
    ISSN 1878-1594 ; 1532-1908 ; 1521-690X
    ISSN (online) 1878-1594 ; 1532-1908
    ISSN 1521-690X
    DOI 10.1016/j.beem.2019.101293
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Endoscopic management of gastric wall bleeding and stent blood clot occlusion after endoscopic ultrasound-guided hepaticogastrostomy.

    Fine, Caroline / Rivory, Jérome / Forestier, Julien / Saurin, Jean-Christophe / Sosa-Valencia, Leonardo / Ponchon, Thierry / Pioche, Mathieu

    Endoscopy

    2016  Volume 48, Issue S 01, Page(s) E351–E352

    MeSH term(s) Anastomosis, Surgical/adverse effects ; Endosonography ; Gastroscopy ; Gastrostomy/adverse effects ; Hemostasis, Endoscopic/methods ; Hepatic Duct, Common/surgery ; Humans ; Male ; Melena/etiology ; Melena/therapy ; Middle Aged ; Prosthesis Failure/etiology ; Stents/adverse effects ; Stomach/surgery ; Thrombosis/etiology ; Thrombosis/therapy ; Ultrasonography, Interventional
    Language English
    Publishing date 2016
    Publishing country Germany
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0042-118455
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)
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  7. Article: Endoscopic management of gastric wall bleeding and stent blood clot occlusion after endoscopic ultrasound-guided hepaticogastrostomy

    Fine, Caroline / Rivory, Jérome / Forestier, Julien / Saurin, Jean-Christophe / Sosa-Valencia, Leonardo / Ponchon, Thierry / Pioche, Mathieu

    Endoscopy

    2016  Volume 48, Issue S 01, Page(s) E351–E352

    Language English
    Publishing date 2016-01-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0042-118455
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 669: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 162: Show issues

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  8. Article: Endoscopic management of 345 small rectal neuroendocrine tumours: A national study from the French group of endocrine tumours (GTE).

    Fine, Caroline / Roquin, Guillaume / Terrebonne, Eric / Lecomte, Thierry / Coriat, Romain / Do Cao, Christine / de Mestier, Louis / Coffin, Elise / Cadiot, Guillaume / Nicolli, Patricia / Lepiliez, Vincent / Hautefeuille, Vincent / Ramos, Jeanne / Girot, Paul / Dominguez, Sophie / Céphise, Fritz-Line V / Forestier, Julien / Hervieu, Valérie / Pioche, Mathieu /
    Walter, Thomas

    United European gastroenterology journal

    2019  Volume 7, Issue 8, Page(s) 1102–1112

    Abstract: Introduction: Small rectal neuroendocrine tumours are good candidates for endoscopic resection provided that complete pathological resection (R0) is obtained and their risk of metastatic progression is low. We conducted a large multicentre nationwide ... ...

    Abstract Introduction: Small rectal neuroendocrine tumours are good candidates for endoscopic resection provided that complete pathological resection (R0) is obtained and their risk of metastatic progression is low. We conducted a large multicentre nationwide study to evaluate the outcomes of the management of non-metastatic rectal neuroendocrine tumours ≤2 cm diagnosed endoscopically.
    Patients and methods: The medical records, the endoscopic and pathological findings of patients with non-metastatic rectal neuroendocrine tumours ≤2 cm managed from January 2000-June 2018 in 16 French hospitals, were retrospectively analysed. The primary objective was to describe the proportion of R0 endoscopic resections.
    Results: A total of 329 patients with 345 rectal neuroendocrine tumours were included, 330 (96%) tumours were managed by local treatments: 287 by endoscopy only and 43 by endoscopy followed by transanal endoscopic microsurgery. The final endoscopic R0 rate was 134/345 (39%), which improved from the first endoscopy (54/225, 24%), to the second (60/100, 60%) and the third endoscopy (20/26, 77%). R0 was associated with endoscopic technique (90% for advanced techniques, 40% for mucosectomy and 17% for polypectomy), but not with tumour or patient characteristics. Twenty patients had metastatic disease, which was associated with tumour size ≥10 mm (odds ratio: 9.1, 95% confidence interval (3.5-23.5)), tumour grade G2-G3 (odds ratio: 4.2, (1.5-11.7)), the presence of muscular (odds ratio: ∞, (11.9-∞)) and lymphovascular invasion (odds ratio: 57.2, (5.6-578.9)).
    Conclusions: The resection of small rectal neuroendocrine tumours often requires multiple procedures. Training of endoscopists is necessary in order to better recognise these tumours and to perform the appropriate resection technique.
    MeSH term(s) Endoscopy/adverse effects ; Endoscopy/methods ; Endoscopy/trends ; Female ; Follow-Up Studies ; France/epidemiology ; Humans ; Male ; Middle Aged ; Neoplasm Grading/methods ; Neoplasm Invasiveness/pathology ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/pathology ; Neoplasm Staging/methods ; Neuroendocrine Tumors/diagnostic imaging ; Neuroendocrine Tumors/mortality ; Neuroendocrine Tumors/surgery ; Procedures and Techniques Utilization/statistics & numerical data ; Procedures and Techniques Utilization/trends ; Rectal Neoplasms/diagnostic imaging ; Rectal Neoplasms/pathology ; Reoperation/statistics & numerical data ; Retrospective Studies ; Surgeons/education ; Transanal Endoscopic Microsurgery/methods ; Treatment Outcome
    Language English
    Publishing date 2019-07-04
    Publishing country England
    Document type Comparative Study ; Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2728585-6
    ISSN 2050-6414 ; 2050-6406
    ISSN (online) 2050-6414
    ISSN 2050-6406
    DOI 10.1177/2050640619861883
    Database MEDical Literature Analysis and Retrieval System OnLINE

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