LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 24

Search options

  1. Article: Acute coronary syndrome and renal impairment: a systematic review.

    Di Mauro, Marco / Fiorentini, Vincenzo / Mistrulli, Raffaella / Veneziano, Francesco Antonio / De Luca, Leonardo

    Reviews in cardiovascular medicine

    2022  Volume 23, Issue 2, Page(s) 49

    Abstract: Background: Coronary artery disease (CAD) and chronic kidney disease (CKD) may reciprocally influence each other. Patients with CAD and CKD have an increased risk of both ischemic and hemorrhagic events.: Methods: In the present review, we summarize ... ...

    Abstract Background: Coronary artery disease (CAD) and chronic kidney disease (CKD) may reciprocally influence each other. Patients with CAD and CKD have an increased risk of both ischemic and hemorrhagic events.
    Methods: In the present review, we summarize the existing literature focusing on the relationship between kidney dysfunction and acute coronary syndromes (ACS) in terms of risk factors, complications, and prognosis. We discuss also about the best evidence-based strategies to prevent deterioration of renal function in patients with CAD.
    Results: Patients with CKD less frequently receive an invasive management (percutaneous or surgical revascularization) and potent antithrombotic drugs. Nevertheless, recent evidence suggests they would benefit from a selective invasive management, especially in case of ACS.
    Conclusion: Patients with CKD and CAD represent a challenging population, more randomized controlled trials and meta-analyses are needed to better define the best therapeutic strategy during an ACS episode.
    MeSH term(s) Acute Coronary Syndrome/diagnosis ; Acute Coronary Syndrome/therapy ; Coronary Artery Disease/complications ; Coronary Artery Disease/diagnostic imaging ; Coronary Artery Disease/therapy ; Hemorrhage/chemically induced ; Humans ; Percutaneous Coronary Intervention/adverse effects ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/therapy ; Risk Factors
    Language English
    Publishing date 2022-02-28
    Publishing country Singapore
    Document type Systematic Review
    ZDB-ID 2108910-3
    ISSN 1530-6550
    ISSN 1530-6550
    DOI 10.31083/j.rcm2302049
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Association between Immune Checkpoint Inhibitors and Atherosclerotic Cardiovascular Disease Risk: Another Brick in the Wall.

    Piras, Linda / Zuccanti, Michela / Russo, Paola / Riccio, Francesca / Agresti, Antonio / Lustri, Camilla / Dardani, Domenico / Ferrera, Armando / Fiorentini, Vincenzo / Tocci, Giuliano / Tini Melato, Giacomo / Volpe, Massimo / Barbato, Emanuele / Battistoni, Allegra

    International journal of molecular sciences

    2024  Volume 25, Issue 5

    Abstract: In recent years, immune checkpoint inhibitors have significantly changed the field of oncology, emerging as first-line treatment, either alone or in combination with other regimens, for numerous malignancies, improving overall survival and progression- ... ...

    Abstract In recent years, immune checkpoint inhibitors have significantly changed the field of oncology, emerging as first-line treatment, either alone or in combination with other regimens, for numerous malignancies, improving overall survival and progression-free survival in these patients. However, immune checkpoint inhibitors might also cause severe or fatal immune-related adverse events, including adverse cardiovascular events. Initially, myocarditis was recognized as the main immune checkpoint inhibitor-related cardiac event, but our knowledge of other potential immune-related cardiovascular adverse events continues to broaden. Recently, preclinical and clinical data seem to support an association between immune checkpoint inhibitors and accelerated atherosclerosis as well as atherosclerotic cardiovascular events such as cardiac ischemic disease, stroke, and peripheral artery disease. In this review, by offering a comprehensive overview of the pivotal role of inflammation in atherosclerosis, we focus on the potential molecular pathways underlying the effects of immune checkpoint inhibitors on cardiovascular diseases. Moreover, we provide an overview of therapeutic strategies for cancer patients undergoing immunotherapy to prevent the development of cardiovascular diseases.
    MeSH term(s) Humans ; Immune Checkpoint Inhibitors/therapeutic use ; Cardiovascular Diseases/etiology ; Cardiotoxicity/etiology ; Neoplasms/drug therapy ; Myocarditis/etiology ; Heart Diseases/etiology ; Atherosclerosis/etiology ; Immunotherapy/adverse effects
    Chemical Substances Immune Checkpoint Inhibitors
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25052502
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: A three-order-parameter bistable magnetoelectric multiferroic metal.

    Urru, Andrea / Ricci, Francesco / Filippetti, Alessio / Íñiguez, Jorge / Fiorentini, Vincenzo

    Nature communications

    2020  Volume 11, Issue 1, Page(s) 4922

    Abstract: Using first-principles calculations we predict that the layered-perovskite metal ... ...

    Abstract Using first-principles calculations we predict that the layered-perovskite metal Bi
    Language English
    Publishing date 2020-10-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-020-18664-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Book ; Conference proceedings: Computational materials science

    Fiorentini, Vincenzo

    selected papers of the twelfth international workshop (CMS 2002) ; Villasimius, Sardinia, Italy, 23 - 29 September, 2002 ; [ ... Twelfth International Workshop on Computational Materials Science ...]

    (Computational materials science ; 30.2004,1/2)

    2004  

    Title variant Nebent.:Selected papers of the Twelfth International Workshop on Computational Materials Science ; Selected papers of the Twelfth International Workshop on Computational Materials Science
    Institution International Workshop on Computational Materials Science
    Event/congress CMS (12, 2002.09.23-29, Villasimius) ; International Workshop on Computational Materials Science (12, 2002.09.23-29, Villasimius)
    Author's details ed.: V. Fiorentini
    Series title Computational materials science ; 30.2004,1/2
    Language English
    Size X, 188 S, Ill., graph. Darst
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Document type Book ; Conference proceedings
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

  5. Book ; Online: A three-order-parameter bistable magnetoelectric multiferroic metal

    Urru, Andrea / Ricci, Francesco / Filippetti, Alessio / Iniguez, Jorge / Fiorentini, Vincenzo

    2020  

    Abstract: Using first-principles calculations we predict that the layered-perovskite metal Bi$_5$Mn$_5$O$_{17}$ is a ferromagnet, ferroelectric, and ferrotoroid which may realize the long sought-after goal of a room-temperature ferromagnetic single-phase ... ...

    Abstract Using first-principles calculations we predict that the layered-perovskite metal Bi$_5$Mn$_5$O$_{17}$ is a ferromagnet, ferroelectric, and ferrotoroid which may realize the long sought-after goal of a room-temperature ferromagnetic single-phase multiferroic with large, strongly coupled, primary-order polarization and magnetization. Bi$_5$Mn$_5$O$_{17}$ has two nearly energy-degenerate ground states with mutually orthogonal vector order parameters (polarization, magnetization, ferrotoroidicity), which can be rotated globally by switching between ground states. Giant cross-coupling magnetoelectric and magnetotoroidic effects, as well as optical non-reciprocity, are thus expected. Importantly, Bi$_5$Mn$_5$O$_{17}$ should be thermodynamically stable in O-rich growth conditions, and hence experimentally accessible.

    Comment: 7 pages, 7 figures
    Keywords Condensed Matter - Materials Science ; Condensed Matter - Mesoscale and Nanoscale Physics
    Publishing date 2020-10-01
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  6. Article ; Online: Theory of thermoelectricity in Mg

    Farris, Roberta / Maccioni, Maria Barbara / Filippetti, Alessio / Fiorentini, Vincenzo

    Journal of physics. Condensed matter : an Institute of Physics journal

    2018  Volume 31, Issue 6, Page(s) 65702

    Abstract: We study the electronic transport coefficients and the thermoelectric figure of merit ZT in [Formula: see text]-doped ... ...

    Abstract We study the electronic transport coefficients and the thermoelectric figure of merit ZT in [Formula: see text]-doped Mg
    Language English
    Publishing date 2018-11-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472968-4
    ISSN 1361-648X ; 0953-8984
    ISSN (online) 1361-648X
    ISSN 0953-8984
    DOI 10.1088/1361-648X/aaf364
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Book ; Online: High thermoelectric figure of merit and thermopower in layered perovskite oxides

    Fiorentini, Vincenzo / Farris, Roberta / Argiolas, Edoardo / Maccioni, Maria Barbara

    2019  

    Abstract: We predict high thermoelectric efficiency in the layered perovskite La$_2$Ti$_2$O$_7$, based on calculations (mostly ab-initio) of the electronic structure, transport coefficients, and thermal conductivity in a wide temperature range. The figure of merit ...

    Abstract We predict high thermoelectric efficiency in the layered perovskite La$_2$Ti$_2$O$_7$, based on calculations (mostly ab-initio) of the electronic structure, transport coefficients, and thermal conductivity in a wide temperature range. The figure of merit $ZT$ computed with a temperature-dependent relaxation time increases monotonically from just above 1 at room temperature to over 2.5 at 1200 K, at an optimal carrier density of around 10$^{20}$ cm$^{-3}$. The Seebeck thermopower coefficient is between 200 and 300 $\mu$V/K at optimal doping, but can reach nearly 1 mV/K at low doping. Much of the potential of this material is due to its lattice thermal conductivity of order 1 W/(K m); using a model based on ab initio anharmonic calculations, we interpret this low value as due to effective phonon confinement within the layered-structure blocks.

    Comment: 18 preprint pages, 9 figures, accepted on PR Materials
    Keywords Condensed Matter - Materials Science
    Publishing date 2019-01-15
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  8. Article ; Online: Prediction of a native ferroelectric metal.

    Filippetti, Alessio / Fiorentini, Vincenzo / Ricci, Francesco / Delugas, Pietro / Íñiguez, Jorge

    Nature communications

    2016  Volume 7, Page(s) 11211

    Abstract: Over 50 years ago, Anderson and Blount discussed symmetry-allowed polar distortions in metals, spawning the idea that a material might be simultaneously metallic and ferroelectric. While many studies have ever since considered such or similar situations, ...

    Abstract Over 50 years ago, Anderson and Blount discussed symmetry-allowed polar distortions in metals, spawning the idea that a material might be simultaneously metallic and ferroelectric. While many studies have ever since considered such or similar situations, actual ferroelectricity--that is, the existence of a switchable intrinsic electric polarization--has not yet been attained in a metal, and is in fact generally deemed incompatible with the screening by mobile conduction charges. Here we refute this common wisdom and show, by means of first-principles simulations, that native metallicity and ferroelectricity coexist in the layered perovskite Bi5Ti5O17. We show that, despite being a metal, Bi5Ti5O17 can sustain a sizable potential drop along the polar direction, as needed to reverse its polarization by an external bias. We also reveal striking behaviours, as the self-screening mechanism at work in thin Bi5Ti5O17 layers, emerging from the interplay between polar distortions and carriers in this compound.
    Language English
    Publishing date 2016-04-04
    Publishing country England
    Document type Journal Article
    ISSN 2041-1723
    ISSN (online) 2041-1723
    DOI 10.1038/ncomms11211
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Book ; Conference proceedings: Advances in computational materials science II

    Fiorentini, Vincenzo

    proceedings of the VII Italian-Swiss workshop, S. Margherita di Pula, (Cagliari) 19 - 23 September 1997 ; [papers presented at the Seventh Italian-Swiss Workshop on Computational Materials Science]

    (Conference proceedings / Italian Physical Society ; 61)

    1998  

    Title variant Progresso della scienza dei Materiali computazionale II
    Institution Workshop Italiano-Svizzero Progresso della Scienza dei Materiali Computazionale
    Event/congress Italian Swiss Workshop on Computational Materials Science (7, 1997.09.19-23, S.MargheritadiPulaCagliari) ; Italian-Swiss Workshop (7, 1997.09.19-23, S.MargheritadiPulaCagliari) ; Workshop Italiano-Svizzero (7, 1997.09.19-23, S.MargheritadiPulaCagliari)
    Author's details ed. by V. Fiorentini
    Series title Conference proceedings / Italian Physical Society ; 61
    Language English
    Size IX, 122 S, ill, 25 cm
    Publisher Italian Physical Society
    Publishing place Bologna
    Document type Book ; Conference proceedings
    Note At head of title: Italian physical society ; Centenary 1897-1997 ; Includes bibliographical references
    ISBN 8877941413 ; 9788877941411
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    More links

    Kategorien

  10. Book ; Online: Theory of thermoelectricity in Mg$_3$Sb$_2$ with an energy- and temperature-dependent relaxation time

    Farris, Roberta / Maccioni, Maria Barbara / Filippetti, Alessio / Fiorentini, Vincenzo

    2018  

    Abstract: We study the electronic transport coefficients and the thermoelectric figure of merit ZT in $n$-doped Mg$_3$Sb$_2$ based on density-functional electronic structure and Bloch-Boltzmann transport theory with an energy- and temperature-dependent relaxation ... ...

    Abstract We study the electronic transport coefficients and the thermoelectric figure of merit ZT in $n$-doped Mg$_3$Sb$_2$ based on density-functional electronic structure and Bloch-Boltzmann transport theory with an energy- and temperature-dependent relaxation time. Both the lattice and electronic thermal conductivities affect the final ZT significantly, hence we include the lattice thermal conductivity calculated ab initio. Where applicable, our results are in good agreement with existing experiments, thanks to the treatment of lattice thermal conductivity and the improved description of electronic scattering. ZT increases monotonically in our T range (300 to 700 K), reaching a value of 1.6 at 700 K; it peaks as a function of doping at about 3$\times$10$^{19}$ cm$^{-3}$. At this doping, ZT$>$1 for T$>$500 K.

    Comment: 8 pages, 6 figures, further expanded, now accepted
    Keywords Condensed Matter - Materials Science
    Subject code 541
    Publishing date 2018-07-19
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top