LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 130

Search options

  1. Book ; Thesis: Die evolutionäre Entwicklung der Psyche in Thure von Uexkülls "Theorie der Humanmedizin - Grundlagen ärztlichen Denkens und Handelns"

    Fischer, Katrin

    2009  

    Author's details vorgelegt von Katrin Fischer
    Subject code 610
    Language German
    Size 105 Bl. : graph. Darst., 21 cm
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis München, Univ., Diss., 2009
    HBZ-ID HT016620740
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2010 D 1141 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes.

    Fischer, Katrin / Bradlerova, Michaela / Decker, Thomas / Supper, Verena

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 18651

    Abstract: Intracellular bacteria produce antigens, which serve as potent activators of γδ T cells. Phosphoantigens are presented via a complex of butyrophilins (BTN) to signal infection to human Vγ9+Vδ2+ T cells. Here, we established an in vitro system allowing ... ...

    Abstract Intracellular bacteria produce antigens, which serve as potent activators of γδ T cells. Phosphoantigens are presented via a complex of butyrophilins (BTN) to signal infection to human Vγ9+Vδ2+ T cells. Here, we established an in vitro system allowing for studies of Vγ9+Vδ2+ T cell activity in coculture with epithelial cells infected with the intracellular bacterial pathogen Listeria monocytogenes. We report that the Vγ9+Vδ2+ T cells efficiently control L. monocytogenes growth in such cultures. This effector function requires the expression of members of the BTN3A family on epithelial cells. Specifically, we observed a BTN3A1-independent BTN3A3 activity to present antigen to Vγ9+Vδ2+ T cells. Since BTN3A1 is the only BTN3A associated with phosphoantigen presentation, our study suggests that BTN3A3 may present different classes of antigens to mediate Vγ9+Vδ2+ T cell effector function against L. monocytogenes-infected epithelia.
    MeSH term(s) Humans ; T-Lymphocytes ; Receptors, Antigen, T-Cell, gamma-delta/metabolism ; Butyrophilins/genetics ; Butyrophilins/metabolism ; Listeria monocytogenes/metabolism ; Antigens ; Epithelial Cells/metabolism ; Lymphocyte Activation ; Antigens, CD/metabolism
    Chemical Substances Receptors, Antigen, T-Cell, gamma-delta ; Butyrophilins ; Antigens ; BTN3A1 protein, human ; Antigens, CD
    Language English
    Publishing date 2023-10-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-45587-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book ; Online: Robot Vulnerability and the Elicitation of User Empathy

    Frederiksen, Morten Roed / Fischer, Katrin / Matarić, Maja

    2024  

    Abstract: This paper describes a between-subjects Amazon Mechanical Turk study (n = 220) that investigated how a robot's affective narrative influences its ability to elicit empathy in human observers. We first conducted a pilot study to develop and validate the ... ...

    Abstract This paper describes a between-subjects Amazon Mechanical Turk study (n = 220) that investigated how a robot's affective narrative influences its ability to elicit empathy in human observers. We first conducted a pilot study to develop and validate the robot's affective narratives. Then, in the full study, the robot used one of three different affective narrative strategies (funny, sad, neutral) while becoming less functional at its shopping task over the course of the interaction. As the functionality of the robot degraded, participants were repeatedly asked if they were willing to help the robot. The results showed that conveying a sad narrative significantly influenced the participants' willingness to help the robot throughout the interaction and determined whether participants felt empathetic toward the robot throughout the interaction. Furthermore, a higher amount of past experience with robots also increased the participants' willingness to help the robot. This work suggests that affective narratives can be useful in short-term interactions that benefit from emotional connections between humans and robots.

    Comment: Published by and copyright protected by IEEE, 8 pages, 4 figures, 31st IEEE International Conference on Robot & Human Interactive Communication (RO-MAN 2022)
    Keywords Computer Science - Robotics ; Computer Science - Human-Computer Interaction
    Subject code 629
    Publishing date 2024-01-05
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Book ; Online: Entwicklung von spezifischen Schutzleitfäden für Tätigkeiten mit Biozidprodukten

    Krause, Monika / Schlüter, Urs / Ludwig-Fischer, Katrin / Rietzscher, Hilian / Roitzsch, Michael / Poppek, Ulrich

    (Holzschutzmittel, Rodentizide, Insektizide) : Forschung Projekt F 2308

    2014  

    Institution Bundesanstalt für Arbeitsschutz und Arbeitsmedizin
    Author's details Autoren: Monika Krause, Dr. Urs Schlüter, Dr. Katrin Ludwig-Fischer, Hielian Rietzscher, Dr. Michael Roitzsch ; Fachliche Unterstützung: Ulrich Poppek ; Bundesanstalt für Arbeitsschutz und Arbeitsmedizin
    Keywords Biozide, Exposition, Schädlingsbekämpfung, Schutzleitfäden, Schutzmaßnahmen, ordnungsgemäße Verwendung, Organisationsregeln, Hygieneregeln, Gestaltung von Arbeitsverfahren
    Language German
    Size 1 Online-Ressource (120 Seiten), Illustrationen
    Publisher Bundesanstalt für Arbeitsschutz und Arbeitsmedizin
    Publishing place Dortmund
    Publishing country Germany
    Document type Book ; Online
    HBZ-ID HT019873903
    ISBN 9783882610314 ; 388261031X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Book ; Online: The Effect of Trust and its Antecedents on Robot Acceptance

    Fischer, Katrin / Kim, Donggyu / Hong, Joo-Wha

    2023  

    Abstract: As social and socially assistive robots are becoming more prevalent in our society, it is beneficial to understand how people form first impressions of them and eventually come to trust and accept them. This paper describes an Amazon Mechanical Turk ... ...

    Abstract As social and socially assistive robots are becoming more prevalent in our society, it is beneficial to understand how people form first impressions of them and eventually come to trust and accept them. This paper describes an Amazon Mechanical Turk study (n = 239) that investigated trust and its antecedents trustworthiness and first impressions. Participants evaluated the social robot Pepper's warmth and competence as well as trustworthiness characteristics ability, benevolence and integrity followed by their trust in and intention to use the robot. Mediation analyses assessed to what degree participants' first impressions affected their willingness to trust and use it. Known constructs from user acceptance and trust research were introduced to explain the pathways in which one perception predicted the next. Results showed that trustworthiness and trust, in serial, mediated the relationship between first impressions and behavioral intention.

    Comment: In SCRITA 2023 Workshop Proceedings (arXiv:2311.05401) held in conjunction with 32nd IEEE International Conference on Robot & Human Interactive Communication, 28/08 - 31/08 2023, Busan (Korea)
    Keywords Computer Science - Robotics ; Computer Science - Human-Computer Interaction
    Subject code 629
    Publishing date 2023-11-11
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Book ; Online ; Thesis: Monotonie in der Zugverkehrsleitung

    Brüngger, Jonas [Verfasser] / Thüring, Manfred [Akademischer Betreuer] / Fischer, Katrin [Akademischer Betreuer] / Thüring, Manfred [Gutachter] / Fischer, Katrin [Gutachter]

    2021  

    Author's details Jonas Brüngger ; Gutachter: Manfred Thüring, Katrin Fischer ; Manfred Thüring, Katrin Fischer
    Keywords Psychologie ; Psychology
    Subject code sg150
    Language German
    Publisher Technische Universität Berlin
    Publishing place Berlin
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article: Integration der Versichertenperspektive in die Qualitätsbewertung der Begutachtung.

    Rosburg, Timm / Lohss, Regine / Bachmann, Monica S / Meyer, Brigitte Walter / Boer, Wout de / Fischer, Katrin / Kunz, Regina

    Therapeutische Umschau. Revue therapeutique

    2023  Volume 80, Issue 2, Page(s) 78–84

    Abstract: Integration of the Insured Person's Perspective in the Quality Assessment of Medical ... ...

    Title translation Integration of the Insured Person's Perspective in the Quality Assessment of Medical Evaluations.
    Abstract Integration of the Insured Person's Perspective in the Quality Assessment of Medical Evaluations
    MeSH term(s) Humans ; Disability Evaluation ; Surveys and Questionnaires ; Switzerland
    Language German
    Publishing date 2023-04-17
    Publishing country Switzerland
    Document type English Abstract ; Journal Article
    ZDB-ID 82044-1
    ISSN 1664-2864 ; 0040-5930
    ISSN (online) 1664-2864
    ISSN 0040-5930
    DOI 10.1024/0040-5930/a001414
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.180: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Dynamic control of gene expression by ISGF3 and IRF1 during IFNβ and IFNγ signaling.

    Ravi Sundar Jose Geetha, Aarathy / Fischer, Katrin / Babadei, Olga / Smesnik, Georg / Vogt, Alex / Platanitis, Ekaterini / Müller, Mathias / Farlik, Matthias / Decker, Thomas

    The EMBO journal

    2024  

    Abstract: Type I interferons (IFN-I, including IFNβ) and IFNγ produce overlapping, yet clearly distinct immunological activities. Recent data show that the distinctness of global transcriptional responses to the two IFN types is not apparent when comparing their ... ...

    Abstract Type I interferons (IFN-I, including IFNβ) and IFNγ produce overlapping, yet clearly distinct immunological activities. Recent data show that the distinctness of global transcriptional responses to the two IFN types is not apparent when comparing their immediate effects. By analyzing nascent transcripts induced by IFN-I or IFNγ over a period of 48 h, we now show that the distinctiveness of the transcriptomes emerges over time and is based on differential employment of the ISGF3 complex as well as of the second-tier transcription factor IRF1. The distinct transcriptional properties of ISGF3 and IRF1 correspond with a largely diverse nuclear protein interactome. Mechanistically, we describe the specific input of ISGF3 and IRF1 into enhancer activation and the regulation of chromatin accessibility at interferon-stimulated genes (ISG). We further report differences between the IFN types in altering RNA polymerase II pausing at ISG 5' ends. Our data provide insight how transcriptional regulators create immunological identities of IFN-I and IFNγ.
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 586044-1
    ISSN 1460-2075 ; 0261-4189
    ISSN (online) 1460-2075
    ISSN 0261-4189
    DOI 10.1038/s44318-024-00092-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1808: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 100: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Book ; Online ; Thesis: Lebenszyklusorientierte Projektentwicklung öffentlicher Immobilien als PPP

    Fischer, Katrin

    ein Value-Management-Ansatz ; Dissertation

    (Schriftenreihe der Professur Betriebswirtschaftslehre im Bauwesen ; 1)

    2008  

    Abstract: Die Arbeit befasst sich mit Anreiz-, Kontroll- und Steuerungsmechanismen bei PPP-Projekten und gibt konkrete Empfehlungen für die Gestaltung des Planungsprozesses sowie der Outputspezifikationen und Vergütungsmechanismen in PPP-Verträgen. Dabei wird die ... ...

    Author's details von Katrin Fischer
    Series title Schriftenreihe der Professur Betriebswirtschaftslehre im Bauwesen ; 1
    Abstract Die Arbeit befasst sich mit Anreiz-, Kontroll- und Steuerungsmechanismen bei PPP-Projekten und gibt konkrete Empfehlungen für die Gestaltung des Planungsprozesses sowie der Outputspezifikationen und Vergütungsmechanismen in PPP-Verträgen. Dabei wird die grundsätzliche Wirkungsweise des in Ansätzen in Literatur und Praxis bereits vorhandenen Instrumentariums zur Entwicklung, Leistungsüberwachung und strategischen Steuerung von PPP-Projekten unter Verwendung der Neuen Institutionenökonomie wissenschaftlich untersucht. Im Ergebnis entsteht der Value- Management-Ansatz, in dem die wesentlichen technischen, funktionalen und transaktionsspezifischen Werttreiber zusammengeführt und verknüpft werden. Auf Basis der theoretischen Erkenntnisse sowie untersuchter Fallstudien im Verwaltungs-, Schul- und Krankenhausbereich im In- und Ausland wird der Value-Management-Ansatz weiterentwickelt und vervollständigt. -- Immobilie

    Lebenszykluskosten

    Outputspezifikation

    Projektentwicklung

    Value Management PPP/PFI

    contract management

    controlling

    output specification

    payment mechanism

    The analysis provides insights into the current application of incentive, monitoring and controlling mechanisms in PPP projects. A different planning process as well as model output specifications and effective payment mechanism for PPP contracts are discussed. The Theory of New Institutional Economics gives insight into the functioning of the different monitoring instruments and controlling mechanisms in PPP projects. As a result, a Value Management Approach for PPP projects is proposed which brings together technical, functional and transactional value drivers. A case study of PPP projects in the administration, education and health sector is used to identify how these different contract mechanisms are used in practice. From that, conclusions were drawn to further develop the Value Management Approach.
    Keywords Öffentlich-private Partnerschaft ; Projektfinanzierung ; Projektmanagement ; Lebenszyklus ; Shareholder Value ; Neue Institutionenökonomik
    Language German
    Size Online-Ressource (PDF-Datei: XV, 196, XXXVI S., 2,26 MB), graph. Darst
    Edition [Online-Ausg.]
    Publisher Univ.-Verl
    Publishing place Weimar
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Zugl.: Weimar, Univ., Fak. BIng., Diss., 2008
    Note IMD-Felder maschinell generiert
    ISBN 9783860683385 ; 3860683381
    Database ECONomics Information System

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Book ; Online ; Thesis: Lebenszyklusorientierte Projektentwicklung öffentlicher Immobilien als PPP

    Fischer, Katrin

    ein Value-Management-Ansatz ; Dissertation

    (Schriftenreihe der Professur Betriebswirtschaftslehre im Bauwesen ; 1)

    2008  

    Abstract: Die Arbeit befasst sich mit Anreiz-, Kontroll- und Steuerungsmechanismen bei PPP-Projekten und gibt konkrete Empfehlungen für die Gestaltung des Planungsprozesses sowie der Outputspezifikationen und Vergütungsmechanismen in PPP-Verträgen. Dabei wird die ... ...

    Author's details von Katrin Fischer
    Series title Schriftenreihe der Professur Betriebswirtschaftslehre im Bauwesen ; 1
    Abstract Die Arbeit befasst sich mit Anreiz-, Kontroll- und Steuerungsmechanismen bei PPP-Projekten und gibt konkrete Empfehlungen für die Gestaltung des Planungsprozesses sowie der Outputspezifikationen und Vergütungsmechanismen in PPP-Verträgen. Dabei wird die grundsätzliche Wirkungsweise des in Ansätzen in Literatur und Praxis bereits vorhandenen Instrumentariums zur Entwicklung, Leistungsüberwachung und strategischen Steuerung von PPP-Projekten unter Verwendung der Neuen Institutionenökonomie wissenschaftlich untersucht. Im Ergebnis entsteht der Value- Management-Ansatz, in dem die wesentlichen technischen, funktionalen und transaktionsspezifischen Werttreiber zusammengeführt und verknüpft werden. Auf Basis der theoretischen Erkenntnisse sowie untersuchter Fallstudien im Verwaltungs-, Schul- und Krankenhausbereich im In- und Ausland wird der Value-Management-Ansatz weiterentwickelt und vervollständigt. -- Immobilie

    Lebenszykluskosten

    Outputspezifikation

    Projektentwicklung

    Value Management PPP/PFI

    contract management

    controlling

    output specification

    payment mechanism

    The analysis provides insights into the current application of incentive, monitoring and controlling mechanisms in PPP projects. A different planning process as well as model output specifications and effective payment mechanism for PPP contracts are discussed. The Theory of New Institutional Economics gives insight into the functioning of the different monitoring instruments and controlling mechanisms in PPP projects. As a result, a Value Management Approach for PPP projects is proposed which brings together technical, functional and transactional value drivers. A case study of PPP projects in the administration, education and health sector is used to identify how these different contract mechanisms are used in practice. From that, conclusions were drawn to further develop the Value Management Approach.
    Language German
    Size Online-Ressource (PDF-Datei: XV, 196, XXXVI S., 2,26 MB), graph. Darst
    Edition [Online-Ausg.]
    Publisher Univ.-Verl
    Publishing place Weimar
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Univ., Fak. BIng., Diss.--Weimar, 2008
    ISBN 9783860683385 ; 3860683381
    Database Former special subject collection: coastal and deep sea fishing

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top