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  1. Article ; Online: Plasma cell vulvitis: A case report.

    Fisher, Lauren / Alnaggar, Eman

    Case reports in women's health

    2024  Volume 42, Page(s) e00601

    Abstract: Plasma cell vulvitis (PCV) is a rare inflammatory condition characterised by plasma cell infiltration in the vulva. A woman in her 80s was referred to a specialist gynaecology clinic with chronic, painful vulval ulcers that were non-responsive to topical ...

    Abstract Plasma cell vulvitis (PCV) is a rare inflammatory condition characterised by plasma cell infiltration in the vulva. A woman in her 80s was referred to a specialist gynaecology clinic with chronic, painful vulval ulcers that were non-responsive to topical betamethasone. Following a biopsy confirming PCV, combination therapy was initiated. This included non-pharmacological management, such as promoting aeration and using hypoallergenic clothing and washes, combined with the daily application of clobetasone cream 0.05% and clindamycin cream 0.1%. Additionally, topical estriol 1% was applied twice weekly. The patient experienced rapid symptom resolution, with the PCV lesion healing within six weeks of starting treatment. This case documents the rare occurrence of plasma cell vulvitis presenting as chronic vulval ulceration, and proposes a treatment regimen worth considering in instances where monotherapy has been ineffective.
    Language English
    Publishing date 2024-03-26
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2800286-6
    ISSN 2214-9112 ; 2214-9112
    ISSN (online) 2214-9112
    ISSN 2214-9112
    DOI 10.1016/j.crwh.2024.e00601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Management of postpartum preeclampsia complicated by idiopathic pericarditis: A case report.

    Fisher, Lauren / Alnaggar, Eman

    Case reports in women's health

    2024  Volume 42, Page(s) e00599

    Abstract: This case report discusses the rare occurrence of pericarditis with preeclampsia in the antepartum through to postpartum state. A woman in her 30s presented four days postnatally with positional central chest pain, elevated blood pressure and newly ... ...

    Abstract This case report discusses the rare occurrence of pericarditis with preeclampsia in the antepartum through to postpartum state. A woman in her 30s presented four days postnatally with positional central chest pain, elevated blood pressure and newly deranged liver function tests. Echocardiogram demonstrated new pleural effusion and she was diagnosed with preeclampsia and superimposed pericarditis. Her blood pressure was stabilised with a combination treatment regime of labetalol, enalapril and frusemide, whilst her pericarditis responded well to colchicine and ibuprofen. She was eventually discharge on enalapril and colchicine. By her 6-week follow-up she had made a full recovery and she had reported no recurrence of symptoms at the time of writing.
    Language English
    Publishing date 2024-03-31
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2800286-6
    ISSN 2214-9112 ; 2214-9112
    ISSN (online) 2214-9112
    ISSN 2214-9112
    DOI 10.1016/j.crwh.2024.e00599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Uterine perforation associated with gestational trophoblastic disease and arteriovenous malformation: A case report.

    Fisher, Lauren / Bahabri, Amin / Clare, Anna / Shakeri, Babak

    Case reports in women's health

    2023  Volume 41, Page(s) e00579

    Abstract: This case report outlines the clinical course of a young woman who presented as haemodynamically unstable due to uterine perforation. She had undergone suction dilation and curettage three weeks prior and received a diagnosis of complete molar pregnancy. ...

    Abstract This case report outlines the clinical course of a young woman who presented as haemodynamically unstable due to uterine perforation. She had undergone suction dilation and curettage three weeks prior and received a diagnosis of complete molar pregnancy. During her most recent acute presentation, an emergency laparotomy revealed a full-thickness fundal uterine rupture in a region of newly identified arteriovenous malformation. Haemostasis was achieved with the primary repair of the perforation. She was subsequently diagnosed with gestational trophoblastic neoplasm (GTN), a condition characterised by abnormal proliferation of trophoblastic tissue. She received three courses of methotrexate followed by a two-month course of dactinomycin. At one-year surveillance, she had made a complete recovery.
    Language English
    Publishing date 2023-12-19
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2800286-6
    ISSN 2214-9112 ; 2214-9112
    ISSN (online) 2214-9112
    ISSN 2214-9112
    DOI 10.1016/j.crwh.2023.e00579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Detangling the Association Between Traumatic Brain Injury, Mental Health, and Suicide in Active Duty Service Members.

    Zafonte, Ross D / Daneshvar, Daniel Hamed / Fisher, Lauren

    JAMA network open

    2023  Volume 6, Issue 7, Page(s) e2327644

    MeSH term(s) Humans ; Mental Health ; Suicide/psychology ; Mental Disorders ; Brain Injuries, Traumatic/epidemiology
    Language English
    Publishing date 2023-07-03
    Publishing country United States
    Document type Journal Article ; Comment
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2023.27644
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The importance of diverse and accurate descriptions of genital anatomy in textbooks.

    Beni, Rebecca / Fisher, Lauren / Longhurst, Georga J

    Anatomical sciences education

    2022  Volume 15, Issue 5, Page(s) 985–988

    MeSH term(s) Anatomy/education ; Genitalia
    Language English
    Publishing date 2022-06-05
    Publishing country United States
    Document type Letter
    ZDB-ID 2483491-9
    ISSN 1935-9780 ; 1935-9772
    ISSN (online) 1935-9780
    ISSN 1935-9772
    DOI 10.1002/ase.2200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Rich and sparse figurative information in children's memory for colorful places.

    Lange-Küttner, Christiane / Collins, Chenelle L / Ahmed, Rahima K / Fisher, Lauren E

    Developmental psychology

    2022  Volume 59, Issue 2, Page(s) 256–271

    Abstract: The relation between perceptual and conceptual knowledge is a longstanding research question in developmental psychology. Here we tested children's dependence on figurative information with a reaction time/accuracy task. A sample of 151 children from 5 ... ...

    Abstract The relation between perceptual and conceptual knowledge is a longstanding research question in developmental psychology. Here we tested children's dependence on figurative information with a reaction time/accuracy task. A sample of 151 children from 5 to 10 years were assessed from two multicultural and multiracial schools in the London (UK) boroughs City of London and Harrow. A quarter of children in both schools were eligible for free school meals (national average 18.5%). The same 3 × 3 grid with nine individually colored places and a uniform black star as placeholder was tested in three different retrieval conditions: (a) same array as during presentation, (b) one place at a time with placeholder, and (c) one place at a time without placeholder. In a (d) control condition, individual shapes were of the same color as the colorful places. Bayes Factor analyses showed a more unified response toward figurative placeholders in 5- to 6-year-olds. Independently of age, colorful places without a placeholder were hardest to remember. Places were better remembered when a placeholder was added and still better when the spatial context of the entire array was available. Yet unique shapes with distinctive contours and colors as placeholders optimized place memory the most. While place memory accuracy increased with age, reaction times did not become faster. Instead, latencies were longer, the more visual information was available in the retrieval array. A larger perceptual effect was caused by the dynamic where-delay interference task, the sparser the amount of visual information in the retrieval array. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
    MeSH term(s) Humans ; Child ; Bayes Theorem ; Mental Recall ; Reaction Time/physiology ; Form Perception ; London
    Language English
    Publishing date 2022-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2066223-3
    ISSN 1939-0599 ; 0012-1649
    ISSN (online) 1939-0599
    ISSN 0012-1649
    DOI 10.1037/dev0001483
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Beyond the tip of the iceberg: A meta-analysis of the anatomy of the clitoris.

    Longhurst, Georga Jane / Beni, Rebecca / Jeong, Su Ryeon / Pianta, Marina / Soper, Annie Louisa / Leitch, Patricia / De Witte, Gabrielle / Fisher, Lauren

    Clinical anatomy (New York, N.Y.)

    2023  Volume 37, Issue 2, Page(s) 233–252

    Abstract: An understanding of ranges in clitoral anatomy is important for clinicians caring for patients including those who have had female genital mutilation, women seeking genital cosmetic surgery, or trans women seeking reconstructive surgery. The aim of this ... ...

    Abstract An understanding of ranges in clitoral anatomy is important for clinicians caring for patients including those who have had female genital mutilation, women seeking genital cosmetic surgery, or trans women seeking reconstructive surgery. The aim of this meta-analysis is to investigate the ranges in clitoral measurements within the literature. A meta-analysis was performed on Ovid Medline and Embase databases following the PRISMA protocol. Measurements of clitoral structures from magnetic imaging resonance, ultrasound, cadaveric, and living women were extracted and analyzed. Twenty-one studies met the inclusion criteria. The range in addition to the average length and width of the glans (6.40 mm; 5.14 mm), body (25.46 mm; 9.00 mm), crura (52.41 mm; 8.71 mm), bulb (52.00 mm; 10.33 mm), and prepuce (23.19 mm) was calculated. Furthermore, the range and average distance from the clitoris to the external urethral meatus (22.27 mm), vagina (43.14 mm), and anus (76.30 mm) was documented. All erectile and non-erectile structures of the clitoris present with substantial range. It is imperative to expand the literature on clitoral measurements and disseminate the new results to healthcare professionals and the public to reduce the sense of inadequacy and the chances of iatrogenic damage during surgery.
    MeSH term(s) Male ; Female ; Humans ; Clitoris/anatomy & histology ; Vulva/anatomy & histology ; Vagina/anatomy & histology ; Plastic Surgery Procedures ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-09-29
    Publishing country United States
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 1025505-9
    ISSN 1098-2353 ; 0897-3806
    ISSN (online) 1098-2353
    ISSN 0897-3806
    DOI 10.1002/ca.24113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: iCare4Me for FTD: A pilot randomized study to improve self-care in caregivers of persons with frontotemporal degeneration.

    Massimo, Lauren / Hirschman, Karen B / Aryal, Subhash / Quinn, Ryan / Fisher, Lauren / Sharkey, Michelle / Thomas, Gladys / Bowles, Kathryn H / Riegel, Barbara

    Alzheimer's & dementia (New York, N. Y.)

    2023  Volume 9, Issue 2, Page(s) e12381

    Abstract: Introduction: A tremendous burden is placed on frontotemporal degeneration (FTD) caregivers who sacrifice their own self-care to manage the functional impairments of their loved one, contributing to high levels of stress and depression. Health coaching ... ...

    Abstract Introduction: A tremendous burden is placed on frontotemporal degeneration (FTD) caregivers who sacrifice their own self-care to manage the functional impairments of their loved one, contributing to high levels of stress and depression. Health coaching provides support for coping with stress while fostering self-care behaviors. We report on preliminary evidence for efficacy of a virtual health coach intervention aimed at increasing self-care.
    Methods: Thirty-one caregivers of persons with behavioral variant FTD (bvFTD) were assigned randomly to an intervention group, which included 10 coaching sessions over 6 months plus targeted health information or the control group receiving standard care augmented with the health information. Caregiver self-care (primary outcome), stress, depression, coping, and patient behavioral symptoms were collected at enrollment and 3 and 6 months. Change over time was evaluated between the intervention and control groups using linear mixed-effects models.
    Results: There was a significant group-by-time interaction for self-care monitoring (
    Discussion: This randomized controlled trial (RCT) shows promise for health coaching as a way to increase support that is urgently needed to reduce poor outcomes in FTD caregivers.
    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2832891-7
    ISSN 2352-8737 ; 2352-8737
    ISSN (online) 2352-8737
    ISSN 2352-8737
    DOI 10.1002/trc2.12381
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Racial Differences in Clinical Presentation in Individuals Diagnosed With Frontotemporal Dementia.

    Jin, Hannah A / McMillan, Corey T / Yannatos, Isabel / Fisher, Lauren / Rhodes, Emma / Jacoby, Sarah F / Irwin, David J / Massimo, Lauren

    JAMA neurology

    2023  Volume 80, Issue 11, Page(s) 1191–1198

    Abstract: Importance: Prior research suggests there are racial disparities in the presentation of dementia, but this has not been investigated in the context of frontotemporal dementia (FTD).: Objective: To explore racial disparities in dementia severity, ... ...

    Abstract Importance: Prior research suggests there are racial disparities in the presentation of dementia, but this has not been investigated in the context of frontotemporal dementia (FTD).
    Objective: To explore racial disparities in dementia severity, functional impairment, and neuropsychiatric symptoms in individuals with a diagnosis of FTD.
    Design, setting, and participants: This exploratory cross-sectional study of National Alzheimer's Coordinating Center (NACC) data collected between June 2005 to August 2021 evaluated Asian, Black, and White individuals with a diagnosis of FTD (behavioral variant FTD or primary progressive aphasia). Excluded were races with limited data, including American Indian or Alaska Native (n = 4), Native Hawaiian or other Pacific Islander (n = 3), other (n = 13), and unknown (n = 24), and participants with symptom duration more than 4 SDs above the mean.
    Main outcomes and measures: Racial differences at initial NACC visit were examined on Clinical Dementia Rating Dementia Staging Instrument plus NACC Frontotemporal Lobar Degeneration Behavior & Language Domains (FTLD-CDR), Functional Assessment Scale, and Neuropsychiatric Inventory using regression models. Matching was also performed to address the imbalance between racial groups.
    Results: The final sample comprised 2478 individuals, of which 59 (2.4%) were Asian, 63 (2.5%) were Black, and 2356 (95.1%) were White. The mean (SD) age at initial visit was 65.3 (9.4) years and symptom duration at initial visit was 67.5 (35.6) months. Asian and Black individuals were considerably underrepresented, comprising a small percent of the sample. Black individuals had a higher degree of dementia severity on FTLD-CDR (β = 0.64; SE = 0.24; P = .006) and FTLD-CDR sum of boxes (β = 1.21; SE = 0.57; P = .03) and greater functional impairment (β = 3.83; SE = 1.49; P = .01). There were no differences on FTLD-CDR and Functional Assessment Scale between Asian and White individuals. Black individuals were found to exhibit a higher frequency of delusions, agitation, and depression (delusions: odds ratio [OR], 2.18; 95% CI, 1.15-3.93; P = .01; agitation: OR, 1.73; 95% CI, 1.03-2.93; P = .04; depression: OR, 1.75; 95% CI, 1.05-2.92; P = .03). Asian individuals were found to exhibit a higher frequency of apathy (OR, 1.89; 95% CI, 1.09-3.78; P = .03), nighttime behaviors (OR, 1.72; 95% CI, 1.01-2.91; P = .04), and appetite/eating (OR, 1.99; 95% CI, 1.17-3.47; P = .01) compared to White individuals.
    Conclusions and relevance: This exploratory study suggests there are racial disparities in dementia severity, functional impairment, and neuropsychiatric symptoms. Future work must address racial disparities and their underlying determinants as well as the lack of representation of racially minoritized individuals in nationally representative dementia registries.
    MeSH term(s) Humans ; Frontotemporal Dementia/diagnosis ; Cross-Sectional Studies ; Race Factors ; Frontotemporal Lobar Degeneration ; Mental Status and Dementia Tests
    Language English
    Publishing date 2023-09-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2702023-X
    ISSN 2168-6157 ; 2168-6149
    ISSN (online) 2168-6157
    ISSN 2168-6149
    DOI 10.1001/jamaneurol.2023.3093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Time out weekly smile: A pilot test of a virtual respite program.

    Morgan, Brianna / Stites, Shana D / Greenfield, Felicia / Fisher, Lauren / Kalafsky, Megan / Hodgson, Nancy / Massimo, Lauren

    Geriatric nursing (New York, N.Y.)

    2023  Volume 54, Page(s) 178–183

    Abstract: Respite care provides alternative care for persons living with dementia (PLWD) and is intended to alleviate the burden of caregiving. However, the evaluation of respite programs is limited. Time Out Weekly Smile (TOWS) is a virtual intergenerational ... ...

    Abstract Respite care provides alternative care for persons living with dementia (PLWD) and is intended to alleviate the burden of caregiving. However, the evaluation of respite programs is limited. Time Out Weekly Smile (TOWS) is a virtual intergenerational respite care program designed to meet the needs of PLWD and their care partners and provide allied health students opportunities to serve as respite volunteers. This multi-method pilot study aimed to evaluate the experience of TOWS participation for all (i.e., care partners, PLWD, students) and identify outcomes of interest for future efficacy studies. Semi-structured interviews with all participants after experiencing TOWS were analyzed using conventional content analysis methods and student surveys of dementia attitudes were summarized. Results demonstrated lasting mutual benefits for all participants including social connection and creating meaning. Our findings suggest that including all respite care participants in future efficacy studies will elucidate the wide impact of respite care programs.
    MeSH term(s) Humans ; Caregivers ; Dementia ; Pilot Projects
    Language English
    Publishing date 2023-10-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632559-2
    ISSN 1528-3984 ; 0197-4572
    ISSN (online) 1528-3984
    ISSN 0197-4572
    DOI 10.1016/j.gerinurse.2023.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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