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  1. Article ; Online: Golf cart injuries have similar severity to all-terrain vehicle injuries in children: a multicenter comparison over a 5-year period.

    Chang, Henry L / Yorkgitis, Brian K / Armstrong, Lindsey B / Thatch, Keith A / Plumley, Donald A / Petroze, Robin T / Larson, Shawn D / Fitzwater, John W / Lao, Oliver B / Markley, Michele A / Fischer, Anne / Pedroso, Felipe / Neville, Holly L / Snyder, Christopher W

    Trauma surgery & acute care open

    2024  Volume 9, Issue 1, Page(s) e001286

    Abstract: Background: Golf carts (GCs) and all-terrain vehicles (ATVs) are popular forms of personal transport. Although ATVs are considered adventurous and dangerous, GCs are perceived to be safer. Anecdotal experience suggests increasing numbers of both GC and ... ...

    Abstract Background: Golf carts (GCs) and all-terrain vehicles (ATVs) are popular forms of personal transport. Although ATVs are considered adventurous and dangerous, GCs are perceived to be safer. Anecdotal experience suggests increasing numbers of both GC and ATV injuries, as well as high severity of GC injuries in children. This multicenter study examined GC and ATV injuries and compared their injury patterns, resource utilization, and outcomes.
    Methods: Pediatric trauma centers in Florida submitted trauma registry patients age <16 years from January 2016 to June 2021. Patients with GC or ATV mechanisms were identified. Temporal trends were evaluated. Injury patterns, resource utilization, and outcomes for GCs and ATVs were compared. Intensive care unit admission and immediate surgery needs were compared using multivariable logistic regression.
    Results: We identified 179 GC and 496 ATV injuries from 10 trauma centers. GC and ATV injuries both increased during the study period (R
    Conclusions: During the study period, GC and ATV injuries increased. Despite their innocuous perception, GCs had a similar injury burden to ATVs. Heightened safety measures for GCs should be considered.
    Level of evidence: III, prognostic/epidemiological.
    Language English
    Publishing date 2024-05-07
    Publishing country England
    Document type Journal Article
    ISSN 2397-5776
    ISSN (online) 2397-5776
    DOI 10.1136/tsaco-2023-001286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Social determinants of health in pediatric trauma: Associations with injury mechanisms and outcomes in the context of the COVID-19 pandemic.

    Avila, Azalia / Lao, Oliver B / Neville, Holly L / Yorkgitis, Brian K / Chang, Henry L / Thatch, Keith / Plumley, Donald / Larson, Shawn D / Fitzwater, John W / Markley, Michele / Pedroso, Felipe / Fischer, Anne / Armstrong, Lindsey B / Petroze, Robin T / Snyder, Christopher W

    American journal of surgery

    2023  Volume 228, Page(s) 107–112

    Abstract: Background: Relationships between social determinants of health and pediatric trauma mechanisms and outcomes are unclear in context of COVID-19.: Methods: Children <16 years old injured between 2016 and 2021 from ten pediatric trauma centers in ... ...

    Abstract Background: Relationships between social determinants of health and pediatric trauma mechanisms and outcomes are unclear in context of COVID-19.
    Methods: Children <16 years old injured between 2016 and 2021 from ten pediatric trauma centers in Florida were included. Patients were stratified by high vs. low Social Vulnerability Index (SVI). Injury mechanisms studied were child abuse, ATV/golf carts, and firearms. Mechanism incidence trends and mortality were evaluated by interrupted time series and multivariable logistic regression.
    Results: Of 19,319 children, 68% and 32% had high and low SVI, respectively. Child abuse increased across SVI strata and did not change with COVID. ATV/golf cart injuries increased after COVID among children with low SVI. Firearm injuries increased after COVID among children with high SVI. Mortality was predicted by injury mechanism, but was not independently associated with SVI, race, or COVID.
    Conclusion: Social vulnerability influences pediatric trauma mechanisms and COVID effects. Child abuse and firearm injuries should be targeted for prevention.
    MeSH term(s) Child ; Humans ; Adolescent ; Firearms ; Pandemics ; Social Determinants of Health ; Wounds, Gunshot/epidemiology ; COVID-19/epidemiology ; Retrospective Studies
    Language English
    Publishing date 2023-08-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2953-1
    ISSN 1879-1883 ; 0002-9610
    ISSN (online) 1879-1883
    ISSN 0002-9610
    DOI 10.1016/j.amjsurg.2023.08.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Management of spontaneous pneumomediastinum in children.

    Fitzwater, John W / Silva, Naomi N / Knight, Colin G / Malvezzi, Leopoldo / Ramos-Irizarry, Carmen / Burnweit, Cathy A

    Journal of pediatric surgery

    2015  Volume 50, Issue 6, Page(s) 983–986

    Abstract: Purpose: We characterize the outcomes of pediatric spontaneous pneumomediastinum in the largest series to date and propose a management pathway.: Methods: All patients at our institution with ICD-9 code 518.1 confirmed to have isolated radiographic ... ...

    Abstract Purpose: We characterize the outcomes of pediatric spontaneous pneumomediastinum in the largest series to date and propose a management pathway.
    Methods: All patients at our institution with ICD-9 code 518.1 confirmed to have isolated radiographic findings of spontaneous pneumomediastinum between January 2003 and February 2014 were retrospectively reviewed for admission, intensive care unit (ICU) stay, complications, and outcome.
    Results: We identified 96 children with 99 episodes, median age 14.1 years (IQR: 8.7-16.4). Primary symptoms were chest pain, cough, and dyspnea. Most were hospitalized (n=91, 91.9%), with 20 (20.2%) admitted to ICU. Median lengths of stay (LOS) were 1 day (IQR: 1-2) for non-ICU admissions and 3 days (IQR: 2-3) for ICU admissions. The surgical service discharged non-ICU patients 0.94 days earlier than medical services (95% CI 0.38-1.50, p=0.0014). Asthma affected neither LOS nor ICU admission rates. Follow-up imaging, when obtained (n=81, 81.8%), did not alter management. Recurrences occurred in three asthmatics, all after one year. Each was rehospitalized and discharged uneventfully. No patient developed pneumomediastinum-related complications (e.g., pneumothorax, pneumopericardium, or mediastinitis).
    Conclusion: Spontaneous pneumomediastinum without associated comorbidities can be managed with expectant outpatient observation without further imaging. Children with asthma should be treated independent of spontaneous pneumomediastinum.
    MeSH term(s) Adolescent ; Asthma/complications ; Chest Pain/etiology ; Child ; Cough/etiology ; Dyspnea/etiology ; Female ; Humans ; Intensive Care Units ; Length of Stay ; Male ; Mediastinal Emphysema/complications ; Mediastinal Emphysema/diagnostic imaging ; Mediastinal Emphysema/therapy ; Radiography ; Recurrence ; Retrospective Studies ; Watchful Waiting
    Language English
    Publishing date 2015-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2015.03.024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Stents as sole therapy for oesophageal cancer: a prospective analysis of outcomes after placement.

    White, Russell E / Parker, Robert K / Fitzwater, John W / Kasepoi, Zachariah / Topazian, Mark

    The Lancet. Oncology

    2009  Volume 10, Issue 3, Page(s) 240–246

    Abstract: Background: Therapies for inoperable oesophageal cancer include chemoradiotherapy and placement of a self-expanding metal stent (SEMS). Few data are available regarding SEMS as sole therapy for patients with inoperable disease who have not already ... ...

    Abstract Background: Therapies for inoperable oesophageal cancer include chemoradiotherapy and placement of a self-expanding metal stent (SEMS). Few data are available regarding SEMS as sole therapy for patients with inoperable disease who have not already received, or are unfit for, chemoradiotherapy. The aim of this study was to determine survival, adequacy of palliation, and complications after SEMS placement as sole therapy for inoperable oesophageal cancer in a resource-limited setting.
    Methods: Data were prospectively gathered on all patients with oesophageal cancer treated with SEMS between Jan 1, 1999, and May 20, 2008, at a hospital in Kenya where chemoradiotherapy is unavailable. Dysphagia scores, morbidity, mortality, and survival were assessed. Follow-up was done during clinic visits, home visits, and by mobile phone.
    Findings: 1000 stents were placed in 951 patients. Long-term follow-up was obtained for 334 patients (35%) with a median survival of 250 days (IQR 130-431, 95%CI 217-301). Mean dysphagia scores improved from 3.3 (SD 0.6) pre-SEMS (n=697) to 1.0 (SD 1.3) for patients (n=78) still alive and 1.8 (SD 1.2) at time of death (n=165). Survival of 17 patients with follow-up who had perforation during tumour dilation (treated with SEMS) was 283 days (IQR 227-538) similar to the 317 patients with follow-up data who did not have a perforation (245 days, 124-430). 20 patients with a tracheo-oesophageal fistula lived a median of 142 days (IQR 73-329). Early complications occurred in 6% (54 of 951 patients) and late complications occurred in 19% (62 of 334 patients). SEMS-related mortality was 0.3% (three of 951).
    Interpretation: SEMS effectively palliate inoperable oesophageal cancer. Survival may be longer than previously reported when SEMS are placed in all patients with inoperable oesophageal cancer, as in our study, rather than those failing or unfit for chemoradiotherapy. SEMS seem to be an appropriate technology for palliation of oesophageal cancer in resource-limited settings. Given the proportion of patients lost to follow up, these findings merit further confirmation.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Cohort Studies ; Esophageal Neoplasms/mortality ; Esophageal Neoplasms/therapy ; Female ; Humans ; Male ; Metals ; Middle Aged ; Prospective Studies ; Stents ; Treatment Outcome
    Chemical Substances Metals
    Language English
    Publishing date 2009-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2049730-1
    ISSN 1474-5488 ; 1470-2045
    ISSN (online) 1474-5488
    ISSN 1470-2045
    DOI 10.1016/S1470-2045(09)70004-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Esophageal cancer in young people: a case series of 109 cases and review of the literature.

    Dawsey, Sonja P / Tonui, Stanley / Parker, Robert K / Fitzwater, John W / Dawsey, Sanford M / White, Russell E / Abnet, Christian C

    PloS one

    2010  Volume 5, Issue 11, Page(s) e14080

    Abstract: Certain geographically distinct areas of the world have very high rates of esophageal cancer (EC). Previous studies have identified western Kenya as a high risk area for EC with an unusual percentage of cases in subjects 30 years of age or younger. To ... ...

    Abstract Certain geographically distinct areas of the world have very high rates of esophageal cancer (EC). Previous studies have identified western Kenya as a high risk area for EC with an unusual percentage of cases in subjects 30 years of age or younger. To better understand EC in these young patients, we abstracted available data on all 109 young patients diagnosed with EC at Tenwek Hospital, Bomet District, Kenya from January 1996 through June 2009, including age at diagnosis, sex, ethnicity, tumor histology, residence location, and medical interventions. We also attempted to contact all patients or a family member and obtained information on ethnicity, tobacco and alcohol use, family history of cancer, and survival. Sixty (55%) representatives of the 109 young patients were successfully interviewed. The median survival time of these 60 patients was 6.4 months, the most common tumor histology was esophageal squamous cell carcinoma (ESCC) (98%), the M:F ratio was 1.4∶1, and only a few subjects used tobacco (15%) or alcohol (15%). Seventy-nine percent reported a family history of cancer and 43% reported having a family history of EC. In summary, this case series describes the largest number of young EC patients reported to date, and it highlights the uniqueness of the EC experience in western Kenya.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Alcohol Drinking/adverse effects ; Esophageal Neoplasms/etiology ; Esophageal Neoplasms/genetics ; Family Health ; Female ; Humans ; Kenya ; Male ; Risk Factors ; Smoking/adverse effects ; Survival Analysis ; Young Adult
    Language English
    Publishing date 2010-11-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Review
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0014080
    Database MEDical Literature Analysis and Retrieval System OnLINE

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