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Book ; Thesis: Analyse der genetischen Variabilität im Tettnanger Hopfen mit Hilfe von AFLP-Fingerabdrücken

Fleischer, Robert

2003

Author's details	Robert Fleischer
Keywords	Tettnang ; Hopfen ; Genetische Variabilität ; Fingerprint-Verfahren
Subject	Fingerprint-Analyse ; Variabilität ; Genotypische Variabilität ; Genetische Varianz ; Varianz ; Genetische Variation ; Genotypische Heterogenität ; Genetische Variante ; Genetische Diversität ; Gemeiner Hopfen ; Humulus lupulus
Language	German
Size	VII, 101 S. : Ill., graph. Darst., Kt.
Edition	1. Aufl.
Publisher	Cuvillier
Publishing place	Göttingen
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Hohenheim, Univ., Diss., 2002
HBZ-ID	HT013639077
ISBN	3-89873-631-8 ; 978-3-89873-631-2
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

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038/408	available for loan (reading room)	Freihandmagazin (U1)

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Book ; Online: Puzzles in the $B^0_s \rightarrow D_s^{\pm} K^{\mp} $ System

Fleischer, Robert / Malami, Eleftheria

2022

Abstract: Non-leptonic $B^0_s \rightarrow D_s^{\pm} K^{\mp}$ transitions are particularly interesting processes to test the Standard Model. As these decays occur via pure tree diagrams, they allow a theoretically clean determination of the angle $\gamma$ of the ... ...

Abstract	Non-leptonic $B^0_s \rightarrow D_s^{\pm} K^{\mp}$ transitions are particularly interesting processes to test the Standard Model. As these decays occur via pure tree diagrams, they allow a theoretically clean determination of the angle $\gamma$ of the unitarity triangle. Considering recent LHCb results, an intriguing picture arises, showing tension with the Standard Model. Extracting the branching ratios of the underlying $\bar{B}^0_s \rightarrow D_s^{\pm} K^{\mp}$ modes and combining them with information from semileptonic $B_{(s)}$ decays, we arrive at another puzzling situation, in accordance with similar decays. These patterns could be footprints of New Physics. We present a model-independent strategy to include such New-Physics effects and apply it to the data. Interestingly, new contributions of moderate size could accommodate the data. This formalism offers an exciting probe for new sources of CP violation at the future high-precision B physics era. Comment: 6 pages, 3 figures, Contribution to the Proceedings of the 11th International Workshop on the CKM Unitarity Triangle (CKM2021), 22-26 November 2021
Keywords	High Energy Physics - Phenomenology ; High Energy Physics - Experiment
Subject code	612
Publishing date	2022-03-25
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Hawaiian songbird radiations.

Fleischer, Robert C / Campana, Michael G / James, Helen F

Current biology : CB

2022 Volume 32, Issue 20, Page(s) R1070–R1072

Abstract: Robert Fleischer and colleagues introduce the unique songbird fauna of Hawaii and the threats it faces. ...

Abstract	Robert Fleischer and colleagues introduce the unique songbird fauna of Hawaii and the threats it faces.
MeSH term(s)	Animals ; Songbirds ; Hawaii ; Phylogeny
Language	English
Publishing date	2022-10-18
Publishing country	England
Document type	Journal Article
ZDB-ID	1071731-6
ISSN	1879-0445 ; 0960-9822
ISSN (online)	1879-0445
ISSN	0960-9822
DOI	10.1016/j.cub.2022.08.057
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Revealing New Physics in $B^0_s\to D_s^\mp K^\pm$ Decays

Fleischer, Robert / Malami, Eleftheria

2021

Abstract: The $B^0_s\to D_s^\mp K^\pm$ system offers a determination of the Unitarity Triangle angle $\gamma$. Intrigued by an LHCb analysis showing a surprisingly large result in tension with information on the Unitarity Triangle and other $\gamma$ measurements, ... ...

Abstract	The $B^0_s\to D_s^\mp K^\pm$ system offers a determination of the Unitarity Triangle angle $\gamma$. Intrigued by an LHCb analysis showing a surprisingly large result in tension with information on the Unitarity Triangle and other $\gamma$ measurements, we make a transparent study of the measured observables, confirming the LHCb picture. The corresponding $\gamma$ puzzle at the $3\sigma$ level would require CP-violating contributions of New Physics, which should also manifest themselves in the corresponding decay branching ratios. Indeed, we find that the rates of the individual $B^0_s\to D_s^\mp K^\pm$ channels show puzzling patterns, in accordance with similar decays, with tensions up to $4.8\sigma$, thereby making the situation much more exciting. We present a formalism to include New-Physics effects in a model-independent way and apply it to the data to constrain the corresponding parameters. Interestingly, new contributions of moderate size could accommodate the data. Utilising this formalism in the future high-precision $B$ physics era may allow us to finally establish new sources of CP violation. Comment: 16 pages, 4 figures. The current version matches the published one
Keywords	High Energy Physics - Phenomenology ; High Energy Physics - Experiment
Subject code	612
Publishing date	2021-10-08
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Book ; Online: Using $B^0_s\to D_s^\mp K^\pm$ Decays as a Portal to New Physics

Fleischer, Robert / Malami, Eleftheria

2021

Abstract: The system of $B^0_s\to D_s^\mp K^\pm$ decays offers a theoretically clean determination of the angle $\gamma$ of the Unitarity Triangle. A corresponding LHCb analysis resulted in a surprisingly large result, which is in tension with other determinations ...

Abstract	The system of $B^0_s\to D_s^\mp K^\pm$ decays offers a theoretically clean determination of the angle $\gamma$ of the Unitarity Triangle. A corresponding LHCb analysis resulted in a surprisingly large result, which is in tension with other determinations and global analyses of the Unitarity Triangle. Paying special attention to discrete ambiguities, we confirm this picture and resolve a final ambiguity. Moreover, we extract the branching ratios of the underlying $\bar{B}^0_s\to D_s^+K^-$ and $\bar{B}^0_s\to D_s^- K^+$ modes. Combining them with information from semileptonic $B_{(s)}$ decays, we arrive at another puzzling situation, which we obtain also for other decays with similar dynamics. These patterns could be footprints of New Physics in the $b\to c \bar{u} s$ and $b \to u \bar{c} s$ processes which govern the dynamics of the $\bar{B}^0_s\to D_s^\mp K^\pm$ channels. Employing a model-independent parametrisation, we present a strategy to reveal such effects. Applying it to the present data, we obtain strongly correlated New-Physics contributions with potentially large CP-violating phases. We find that new contributions sizeably smaller than the Standard Model amplitudes could actually accommodate the current data. This strategy offers an exciting probe for new sources of CP violation at the future high-precision frontier of $B$ physics. Comment: 36 pages, 5 figures, version to appear in Physical Review D
Keywords	High Energy Physics - Phenomenology ; High Energy Physics - Experiment
Subject code	612
Publishing date	2021-09-10
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comparative Analysis of Annotation Pipelines Using the First Japanese White-Eye (Zosterops japonicus) Genome.

Venkatraman, Madhvi / Fleischer, Robert C / Tsuchiya, Mirian T N

Genome biology and evolution

2021 Volume 13, Issue 5

Abstract: Introduced into Hawaii in the early 1900s, the Japanese white-eye or warbling white-eye (Zosterops japonicus) is now the most abundant land bird in the archipelago. Here, we present the first Z. japonicus genome, sequenced from an individual in its ... ...

Abstract	Introduced into Hawaii in the early 1900s, the Japanese white-eye or warbling white-eye (Zosterops japonicus) is now the most abundant land bird in the archipelago. Here, we present the first Z. japonicus genome, sequenced from an individual in its invasive range. This genome provides an important resource for future studies in invasion genomics. We annotated the genome using two workflows-standalone AUGUSTUS and BRAKER2. We found that AUGUSTUS was more conservative with gene predictions when compared with BRAKER2. The final number of annotated gene models was similar between the two workflows, but standalone AUGUSTUS had over 70% of gene predictions with Blast2GO annotations versus under 30% using BRAKER2. Additionally, we tested whether using RNA-seq data from 47 samples had a significant impact on annotation quality when compared with data from a single sample, as generating RNA-seq data for genome annotation can be expensive and requires well preserved tissue. We found that more data did not significantly change the number of annotated genes using AUGUSTUS but using BRAKER2 the number increased substantially. The results presented here will aid researchers in annotating draft genomes of nonmodel species as well as those studying invasion success.
MeSH term(s)	Animals ; Computational Biology/methods ; Genome ; Male ; Molecular Sequence Annotation/methods ; Passeriformes/classification ; Passeriformes/genetics
Language	English
Publishing date	2021-03-24
Publishing country	England
Document type	Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2495328-3
ISSN	1759-6653 ; 1759-6653
ISSN (online)	1759-6653
ISSN	1759-6653
DOI	10.1093/gbe/evab063
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Article ; Online: Genetic Structure of Endangered Clapper Rail (Rallus longirostris) Populations in Southern California.

Fleischer, Robert C / Fuller, Garth / Ledig, David B

Conservation biology : the journal of the Society for Conservation Biology

2021 Volume 9, Issue 5, Page(s) 1234–1243

Abstract: We assessed the genetic structure of two subspecies of endangered Clapper Rails (Rallus longirostris) in Southern California using DNA fingerprinting to uncover variation in minisatellite DNA. Minisatellite DNA variation in the Salton Sea population of ... ...

Abstract	We assessed the genetic structure of two subspecies of endangered Clapper Rails (Rallus longirostris) in Southern California using DNA fingerprinting to uncover variation in minisatellite DNA. Minisatellite DNA variation in the Salton Sea population of the R. I. yumanensis subspecies was at a level typical of outbred avian species (average proportion of fragments shared, or S, was 0.33). Variation was extremely low (S from 0.63 to 0.77), however, within four coastal, salt-marsh populations of the subspecies R. I. levipes located along a transect extending about 260 km northwest from the Mexican border. Between-population similarity (S
Language	English
Publishing date	2021-06-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	58735-7
ISSN	1523-1739 ; 0888-8892
ISSN (online)	1523-1739
ISSN	0888-8892
DOI	10.1046/j.1523-1739.1995.9051225.x-i1
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Article ; Online: Gene expression reveals immune response strategies of naïve Hawaiian honeycreepers experimentally infected with introduced avian malaria.

Paxton, Kristina L / Cassin-Sackett, Loren / Atkinson, Carter T / Videvall, Elin / Campana, Michael G / Fleischer, Robert C

The Journal of heredity

2023 Volume 114, Issue 4, Page(s) 326–340

Abstract: The unprecedented rise in the number of new and emerging infectious diseases in the last quarter century poses direct threats to human and wildlife health. The introduction to the Hawaiian archipelago of Plasmodium relictum and the mosquito vector that ... ...

Abstract	The unprecedented rise in the number of new and emerging infectious diseases in the last quarter century poses direct threats to human and wildlife health. The introduction to the Hawaiian archipelago of Plasmodium relictum and the mosquito vector that transmits the parasite has led to dramatic losses in endemic Hawaiian forest bird species. Understanding how mechanisms of disease immunity to avian malaria may evolve is critical as climate change facilitates increased disease transmission to high elevation habitats where malaria transmission has historically been low and the majority of the remaining extant Hawaiian forest bird species now reside. Here, we compare the transcriptomic profiles of highly susceptible Hawai'i 'amakihi (Chlorodrepanis virens) experimentally infected with P. relictum to those of uninfected control birds from a naïve high elevation population. We examined changes in gene expression profiles at different stages of infection to provide an in-depth characterization of the molecular pathways contributing to survival or mortality in these birds. We show that the timing and magnitude of the innate and adaptive immune response differed substantially between individuals that survived and those that succumbed to infection, and likely contributed to the observed variation in survival. These results lay the foundation for developing gene-based conservation strategies for Hawaiian honeycreepers by identifying candidate genes and cellular pathways involved in the pathogen response that correlate with a bird's ability to recover from malaria infection.
MeSH term(s)	Animals ; Humans ; Malaria, Avian/genetics ; Malaria, Avian/epidemiology ; Malaria, Avian/parasitology ; Hawaii/epidemiology ; Passeriformes/genetics ; Gene Expression ; Immunity
Language	English
Publishing date	2023-02-27
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	3044-2
ISSN	1465-7333 ; 0022-1503
ISSN (online)	1465-7333
ISSN	0022-1503
DOI	10.1093/jhered/esad017
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Book ; Online: Penguin Effects in $B_d^0\to J/\psi K^0_S$ and $B_s^0\to J/\psi\phi$

Barel, Marten Z. / De Bruyn, Kristof / Fleischer, Robert / Malami, Eleftheria

2022

Abstract: Controlling the contributions from doubly Cabibbo-suppressed penguin topologies in the decays $B_d^0\to J/\psi K^0_S$ and $B_s^0\to J/\psi\phi$ is mandatory to reach the highest possible precision in the measurement of the $B^0_q$--$\bar B^0_q$ ($q=d,s$) ...

Abstract	Controlling the contributions from doubly Cabibbo-suppressed penguin topologies in the decays $B_d^0\to J/\psi K^0_S$ and $B_s^0\to J/\psi\phi$ is mandatory to reach the highest possible precision in the measurement of the $B^0_q$--$\bar B^0_q$ ($q=d,s$) mixing phases $\phi_d$ and $\phi_s$. The penguin contributions can be determined using a strategy based on the $SU(3)$ flavour symmetry of QCD. Using the latest experimental data, we update our combined analysis of the decays $B_d^0\to J/\psi K^0_S$, $B_s^0\to J/\psi\phi$ and their control channels $B_s^0\to J/\psi K^0_S$, $B_d^0\to J/\psi \pi^0$ and $B_d^0\to J/\psi \rho^0$. This allows us to simultaneously determine the penguin parameters and both mixing phases. We discuss how the branching fractions of these decays can be used to probe the size of non-factorisable $SU(3)$-breaking effects, which form the main theoretical uncertainty associated with our $SU(3)$-based strategy, and provide new insights into the factorisation approach. Comment: Contribution to the Proceedings of the 11th International Workshop on the CKM Unitarity Triangle (CKM2021), 22-26 November 2021, The University of Melbourne, Australia
Keywords	High Energy Physics - Phenomenology
Subject code	612
Publishing date	2022-03-28
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Conservation genomics and systematics of a near‐extinct island radiation

Kearns, Anna M. / Campana, Michael G. / Slikas, Beth / Berry, Lainie / Saitoh, Takema / Cibois, Alice / Fleischer, Robert C.

Molecular ecology. 2022 Apr., v. 31, no. 7

2022

Abstract: Conservation benefits from incorporating genomics to explore the impacts of population declines, inbreeding, loss of genetic variation and hybridization. Here we use the near‐extinct Mariana Islands reedwarbler radiation to showcase how ancient DNA ... ...

Abstract	Conservation benefits from incorporating genomics to explore the impacts of population declines, inbreeding, loss of genetic variation and hybridization. Here we use the near‐extinct Mariana Islands reedwarbler radiation to showcase how ancient DNA approaches can allow insights into the population dynamics of extinct species and threatened populations for which historical museum specimens or material with low DNA yield (e.g., scats, feathers) are the only sources for DNA. Despite their having paraphyletic mitochondrial DNA (mtDNA), nuclear single nucleotide polymorphisms (SNPs) support the distinctiveness of critically endangered Acrocephalus hiwae and the other three species in the radiation that went extinct between the 1960s and 1990s. Two extinct species, A. yamashinae and A. luscinius, were deeply divergent from each other and from a third less differentiated lineage containing A. hiwae and extinct A. nijoi. Both mtDNA and SNPs suggest that the two isolated populations of A. hiwae from Saipan and Alamagan Islands are sufficiently distinct to warrant subspecies recognition and separate conservation management. We detected no significant differences in genetic diversity or inbreeding between Saipan and Alamagan, nor strong signatures of geographical structuring within either island. However, the implications of possible signatures of inbreeding in both Saipan and Alamagan, and long‐term population declines in A. hiwae that pre‐date modern anthropogenic threats require further study with denser population sampling. Our study highlights the value that conservation genomics studies of island radiations have as windows onto the possible future for the world's biota as climate change and habitat destruction increasingly fragment their ranges and contribute to rapid declines in population abundances.
Keywords	Acrocephalus ; climate change ; extinct species ; genetic variation ; genomics ; habitat destruction ; hybridization ; mitochondrial DNA ; museums ; paraphyly ; population dynamics
Language	English
Dates of publication	2022-04
Size	p. 1995-2012.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	1126687-9
ISSN	1365-294X ; 0962-1083
ISSN (online)	1365-294X
ISSN	0962-1083
DOI	10.1111/mec.16382
Database	NAL-Catalogue (AGRICOLA)

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