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  1. Article ; Online: Is There a Role for Vagal Nerve Stimulation in the Treatment of Rheumatoid Arthritis?

    Fleischmann, Roy

    Arthritis & rheumatology (Hoboken, N.J.)

    2023  Volume 75, Issue 12, Page(s) 2103–2105

    MeSH term(s) Humans ; Vagus Nerve Stimulation ; Arthritis, Rheumatoid/therapy
    Language English
    Publishing date 2023-09-21
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.42643
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Recent issues in JAK inhibitor safety: perspective for the clinician.

    Fleischmann, Roy

    Expert review of clinical immunology

    2022  Volume 18, Issue 3, Page(s) 295–307

    Abstract: Introduction: Five jakinibs are approved for the treatment of rheumatic diseases. There has been a question of their relative safety to other medications since their approval.: Areas covered: A literature search was conducted in Pub Med for the ... ...

    Abstract Introduction: Five jakinibs are approved for the treatment of rheumatic diseases. There has been a question of their relative safety to other medications since their approval.
    Areas covered: A literature search was conducted in Pub Med for the integrated safety databases of these molecules in their clinical trial program, registries, and insurance claims data and in a prospective head-to-head study compared to tumor necrosis factor inhibitors in a high-risk population for cardiovascular and malignancy events. There were no differences found in the safety databases, registries or insurance claims data indicating jakinibs are more likely to cause major adverse cardiac events, malignancy, venous thrombotic episodes, infections, and mortality compared to other medications. The head-to-head trial found that there were numerically more of these events with the jakinib compared to tumor necrosis factor inhibitors.
    Expert opinion: Cardiac events and malignancy occur more frequently in rheumatoid patients with active disease. Although the safety databases, claims data, and registries suggest that there is no difference in the risks with a jakinib versus biologics, the prospective safety study showed these events occur numerically higher in patients at the highest risk for these events. In this population, one should consider using a biologic before a jakinib.
    MeSH term(s) Antirheumatic Agents/adverse effects ; Arthritis, Rheumatoid/drug therapy ; Humans ; Janus Kinase Inhibitors/adverse effects ; Prospective Studies ; Tumor Necrosis Factor Inhibitors/adverse effects
    Chemical Substances Antirheumatic Agents ; Janus Kinase Inhibitors ; Tumor Necrosis Factor Inhibitors
    Language English
    Publishing date 2022-02-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1080/1744666X.2022.2039122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Results of Well-conducted Negative Clinical Trials Should Be Reported in a Peer-reviewed Journal.

    Fleischmann, Roy

    The Journal of rheumatology

    2021  Volume 48, Issue 7, Page(s) 957–959

    MeSH term(s) Humans ; Publishing
    Language English
    Publishing date 2021-04-15
    Publishing country Canada
    Document type Editorial ; Comment
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.201622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Biologic disease-modifying anti-rheumatic drugs and kinase inhibitors: differences in efficacy and safety in rheumatoid arthritis.

    Fleischmann, Roy

    Clinical rheumatology

    2021  Volume 40, Issue 11, Page(s) 4369–4372

    MeSH term(s) Antirheumatic Agents/adverse effects ; Arthritis, Rheumatoid/drug therapy ; Biological Products/adverse effects ; Humans
    Chemical Substances Antirheumatic Agents ; Biological Products
    Language English
    Publishing date 2021-09-24
    Publishing country Germany
    Document type Editorial
    ZDB-ID 604755-5
    ISSN 1434-9949 ; 0770-3198
    ISSN (online) 1434-9949
    ISSN 0770-3198
    DOI 10.1007/s10067-021-05933-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Tofacitinib monotherapy in psoriatic arthritis-what is missing?

    Fleischmann, Roy

    The Lancet. Rheumatology

    2020  Volume 3, Issue 1, Page(s) e3–e5

    Language English
    Publishing date 2020-11-16
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(20)30395-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: 2019 update of the American College of Rheumatology- recommended rheumatoid arthritis disease activity measures: comment on the article by England et al.

    Fleischmann, Roy

    Arthritis care & research

    2020  Volume 72, Issue 5, Page(s) 736

    MeSH term(s) Antirheumatic Agents ; Arthritis, Rheumatoid ; Humans ; Rheumatology ; United States ; Universities
    Chemical Substances Antirheumatic Agents
    Language English
    Publishing date 2020-02-11
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 645059-3
    ISSN 2151-4658 ; 0893-7524 ; 2151-464X
    ISSN (online) 2151-4658
    ISSN 0893-7524 ; 2151-464X
    DOI 10.1002/acr.24153
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Jack pot! What can we learn about registries with respect to treatment cycling in rheumatoid arthritis?

    Pope, Janet E / Fleischmann, Roy M

    Annals of the rheumatic diseases

    2023  Volume 82, Issue 2, Page(s) 161–163

    MeSH term(s) Humans ; Arthritis, Rheumatoid/drug therapy ; Registries ; Antirheumatic Agents/therapeutic use
    Chemical Substances Antirheumatic Agents
    Language English
    Publishing date 2023-01-06
    Publishing country England
    Document type Editorial
    ZDB-ID 7090-7
    ISSN 1468-2060 ; 0003-4967
    ISSN (online) 1468-2060
    ISSN 0003-4967
    DOI 10.1136/ard-2022-223071
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A Summary of 2018 and What Lies Ahead for Rheumatology and Therapy in 2019.

    Fleischmann, Roy

    Rheumatology and therapy

    2019  Volume 6, Issue 1, Page(s) 1–3

    Language English
    Publishing date 2019-01-05
    Publishing country England
    Document type Editorial
    ZDB-ID 2783278-8
    ISSN 2198-6584 ; 2198-6576
    ISSN (online) 2198-6584
    ISSN 2198-6576
    DOI 10.1007/s40744-018-0136-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Looking Back on 2019 in Rheumatology and What to Expect from 2020.

    Fleischmann, Roy

    Rheumatology and therapy

    2019  Volume 7, Issue 1, Page(s) 1–3

    Language English
    Publishing date 2019-12-10
    Publishing country England
    Document type Editorial
    ZDB-ID 2783278-8
    ISSN 2198-6584 ; 2198-6576
    ISSN (online) 2198-6584
    ISSN 2198-6576
    DOI 10.1007/s40744-019-00188-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Dr. Fleischmann replies.

    Fleischmann, Roy

    The Journal of rheumatology

    2019  Volume 46, Issue 12, Page(s) 1642

    Language English
    Publishing date 2019-07-15
    Publishing country Canada
    Document type Letter ; Comment
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.190603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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