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Article: Management of acute aortic dissection in critical care.

Flower, Luke / Arrowsmith, Joseph E / Bewley, Jeremy / Cook, Samantha / Cooper, Graham / Flower, Jake / Greco, Renata / Sadeque, Syed / Madhivathanan, Pradeep R

Journal of the Intensive Care Society

2023  Volume 24, Issue 4, Page(s) 409–418

Abstract: Aortic dissections are associated with significant mortality and morbidity, with rapid treatment paramount. They are caused by a tear in the intimal lining of the aorta that extends into the media of the wall. Blood flow through this tear leads to the ... ...

Abstract Aortic dissections are associated with significant mortality and morbidity, with rapid treatment paramount. They are caused by a tear in the intimal lining of the aorta that extends into the media of the wall. Blood flow through this tear leads to the formation of a false passage bordered by the inner and outer layers of the media. Their diagnosis is challenging, with most deaths caused by aortic dissection diagnosed at post-mortem. Aortic dissections are classified by location and chronicity, with management strategies depending on the nature of the dissection. The Stanford method splits aortic dissections into type A and B, with type A dissections involving the ascending aorta. De Bakey classifies dissections into I, II or III depending on their origin and involvement and degree of extension. The key to diagnosis is early suspicion, appropriate imaging and rapid initiation of treatment. Treatment focuses on initial resuscitation, transfer (if possible and required) to a suitable specialist centre, strict blood pressure and heart rate control and potentially surgical intervention depending on the type and complexity of the dissection. Effective post-operative care is extremely important, with awareness of potential post-operative complications and a multi-disciplinary rehabilitation approach required. In this review article we will discuss the aetiology and classifications of aortic dissection, their diagnosis and treatment principles relevant to critical care. Critical care clinicians play a key part in all these steps, from diagnosis through to post-operative care, and thus a thorough understanding is vital.
Language English
Publishing date 2023-03-29
Publishing country England
Document type Journal Article ; Review
ZDB-ID 2701626-2
ISSN 1751-1437 ; 1751-1437
ISSN (online) 1751-1437
ISSN 1751-1437
DOI 10.1177/17511437231162219
Database MEDical Literature Analysis and Retrieval System OnLINE

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