Article ; Online: The molecular cytoarchitecture of the adult mouse brain.
2023 Volume 624, Issue 7991, Page(s) 333–342
Abstract: The function of the mammalian brain relies upon the specification and spatial positioning of diversely specialized cell types. Yet, the molecular identities of the cell types and their positions within individual anatomical structures remain incompletely ...
Abstract | The function of the mammalian brain relies upon the specification and spatial positioning of diversely specialized cell types. Yet, the molecular identities of the cell types and their positions within individual anatomical structures remain incompletely known. To construct a comprehensive atlas of cell types in each brain structure, we paired high-throughput single-nucleus RNA sequencing with Slide-seq |
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MeSH term(s) | Animals ; Mice ; Brain/anatomy & histology ; Brain/cytology ; Brain/metabolism ; Gene Expression Profiling/methods ; High-Throughput Nucleotide Sequencing ; Hypothalamus/cytology ; Hypothalamus/metabolism ; Mesencephalon/cytology ; Mesencephalon/metabolism ; Neuropeptides/metabolism ; Neurotransmitter Agents/metabolism ; Phenotype ; Rhombencephalon/cytology ; Rhombencephalon/metabolism ; Single-Cell Gene Expression Analysis ; Transcriptome/genetics |
Chemical Substances | Neuropeptides ; Neurotransmitter Agents |
Language | English |
Publishing date | 2023-12-13 |
Publishing country | England |
Document type | Journal Article |
ZDB-ID | 120714-3 |
ISSN | 1476-4687 ; 0028-0836 |
ISSN (online) | 1476-4687 |
ISSN | 0028-0836 |
DOI | 10.1038/s41586-023-06818-7 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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