Article ; Online: Torsade de pointe due to QT prolongation following erythromycin administration in a preterm infant.
2021 Volume 77, Issue 7, Page(s) 597–601
Abstract: Background: Neonatal sepsis is a major cause of morbidity and mortality in preterm infants. Chorioamnionitis is an important risk factor for the development of sepsis, therefore neonates born to mothers developing signs of amnionitis need to be treated ... ...
| Abstract | Background: Neonatal sepsis is a major cause of morbidity and mortality in preterm infants. Chorioamnionitis is an important risk factor for the development of sepsis, therefore neonates born to mothers developing signs of amnionitis need to be treated with antibiotics immediately after birth. Case presentation: We describe the case of a 29 weeks preterm infant born to a mother with Conclusions: Erythromycin should be administered in neonates only if no other choice is available, as although generally well tolerated, its administration can be associated with QTc interval prolongation. When no other option is available, paediatricians should be aware to perform cardiac monitoring or at least serial ECGs before and during erythromycin administration. |
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| MeSH term(s) | Pregnancy ; Female ; Infant, Newborn ; Humans ; Torsades de Pointes ; Infant, Premature ; Erythromycin/adverse effects ; Long QT Syndrome/chemically induced ; Long QT Syndrome/diagnosis ; Ureaplasma Infections/drug therapy ; Anti-Bacterial Agents/adverse effects ; Tachycardia | |||||
| Chemical Substances | Erythromycin (63937KV33D) ; Anti-Bacterial Agents | |||||
| Language | English | |||||
| Publishing date | 2021-08-23 | |||||
| Publishing country | England | |||||
| Document type | Case Reports ; Journal Article | |||||
| ZDB-ID | 390197-x | |||||
| ISSN | 1784-973X ; 0001-5385 | |||||
| ISSN (online) | 1784-973X | |||||
| ISSN | 0001-5385 | |||||
| DOI | 10.1080/00015385.2021.1968153 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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