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  1. Article ; Online: Prediction of Deoxynivalenol Contamination in Wheat via Infrared Attenuated Total Reflection Spectroscopy and Multivariate Data Analysis.

    Fomina, Polina / Femenias, Antoni / Tafintseva, Valeria / Freitag, Stephan / Sulyok, Michael / Aledda, Miriam / Kohler, Achim / Krska, Rudolf / Mizaikoff, Boris

    ACS food science & technology

    2024  Volume 4, Issue 4, Page(s) 895–904

    Abstract: The climate crisis further exacerbates the challenges for food production. For instance, the increasingly unpredictable growth of fungal species in the field can lead to an unprecedented high prevalence of several mycotoxins, including the most important ...

    Abstract The climate crisis further exacerbates the challenges for food production. For instance, the increasingly unpredictable growth of fungal species in the field can lead to an unprecedented high prevalence of several mycotoxins, including the most important toxic secondary metabolite produced by
    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ISSN 2692-1944
    ISSN (online) 2692-1944
    DOI 10.1021/acsfoodscitech.3c00674
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  2. Article ; Online: Laser-irradiating infrared attenuated total reflection spectroscopy of articular cartilage: Potential and challenges for diagnosing osteoarthritis.

    Krebs, P / Nägele, M / Fomina, P / Virtanen, V / Nippolainen, E / Shaikh, R / Afara, I O / Töyräs, J / Usenov, I / Sakharova, T / Artyushenko, V / Tafintseva, V / Solheim, J H / Zimmermann, B / Kohler, A / König, O / Saarakkala, S / Mizaikoff, B

    Osteoarthritis and cartilage open

    2024  Volume 6, Issue 2, Page(s) 100466

    Abstract: Objective: A prototype infrared attenuated total reflection (IR-ATR) laser spectroscopic system designed for : Methods: In vitro: Results: Amide and carbohydrate signal behavior was observed to be almost identical between the obtained sparse IR ... ...

    Abstract Objective: A prototype infrared attenuated total reflection (IR-ATR) laser spectroscopic system designed for
    Methods: In vitro
    Results: Amide and carbohydrate signal behavior was observed to be almost identical between the obtained sparse IR data and previously measured FTIR data used for sparse partial least squares discriminant analysis (SPLSDA) to identify the spectral regions relevant to cartilage condition. Contact pressures between 0.3 and 0.4 ​MPa seem to provide the best sparse IR spectra for cylindrical (d ​= ​3 ​mm) probe tips.
    Conclusion: Laser-irradiating IR-ATR spectroscopy is a promising analytical technique for future arthroscopic applications to differentiate healthy and osteoarthritic cartilage tissue. However, this study also revealed that the flexible connection between the laser-based analyzer and the arthroscopic ATR-probe via IR-transparent fiberoptic cables may affect the robustness of the obtained IR data and requires further improvements.
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article
    ISSN 2665-9131
    ISSN (online) 2665-9131
    DOI 10.1016/j.ocarto.2024.100466
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  3. Article ; Online: A Portable Infrared Attenuated Total Reflection Spectrometer for Food Analysis.

    Fomina, Polina / Femenias, Antoni / Hlavatsch, Michael / Scheuermann, Julian / Schäfer, Nicolas / Freitag, Stephan / Patel, Nageshvar / Kohler, Achim / Krska, Rudolf / Koeth, Johannes / Mizaikoff, Boris

    Applied spectroscopy

    2023  Volume 77, Issue 9, Page(s) 1073–1086

    Abstract: The analytical performance of a compact infrared attenuated total reflection spectrometer using a pyroelectric detector array has been evaluated and compared to a conventional laboratory Fourier transform infrared system for applications in food analysis. ...

    Abstract The analytical performance of a compact infrared attenuated total reflection spectrometer using a pyroelectric detector array has been evaluated and compared to a conventional laboratory Fourier transform infrared system for applications in food analysis. Analytical characteristics including sensitivity, repeatability, linearity of the calibration functions, signal-to-noise ratio, and spectral resolution have been derived for both approaches. Representative analytes of relevance in food industries (i.e., organic solvents, fatty acids, and mycotoxins) have been used for the assessment of the performance of the device and to discuss the potential of this technology in food and feed analysis.
    MeSH term(s) Spectroscopy, Fourier Transform Infrared ; Food Analysis ; Fatty Acids/analysis
    Chemical Substances Fatty Acids
    Language English
    Publishing date 2023-08-01
    Publishing country United States
    Document type Journal Article
    ISSN 1943-3530
    ISSN (online) 1943-3530
    DOI 10.1177/00037028231190660
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  4. Article ; Online: Preclassification of Broadband and Sparse Infrared Data by Multiplicative Signal Correction Approach.

    Rehman, Hafeez Ur / Tafintseva, Valeria / Zimmermann, Boris / Solheim, Johanne Heitmann / Virtanen, Vesa / Shaikh, Rubina / Nippolainen, Ervin / Afara, Isaac / Saarakkala, Simo / Rieppo, Lassi / Krebs, Patrick / Fomina, Polina / Mizaikoff, Boris / Kohler, Achim

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 7

    Abstract: Preclassification of raw infrared spectra has often been neglected in scientific literature. Separating spectra of low spectral quality, due to low signal-to-noise ratio, presence of artifacts, and low analyte presence, is crucial for accurate model ... ...

    Abstract Preclassification of raw infrared spectra has often been neglected in scientific literature. Separating spectra of low spectral quality, due to low signal-to-noise ratio, presence of artifacts, and low analyte presence, is crucial for accurate model development. Furthermore, it is very important for sparse data, where it becomes challenging to visually inspect spectra of different natures. Hence, a preclassification approach to separate infrared spectra for sparse data is needed. In this study, we propose a preclassification approach based on Multiplicative Signal Correction (MSC). The MSC approach was applied on human and the bovine knee cartilage broadband Fourier Transform Infrared (FTIR) spectra and on a sparse data subset comprising of only seven wavelengths. The goal of the preclassification was to separate spectra with analyte-rich signals (i.e., cartilage) from spectra with analyte-poor (and high-matrix) signals (i.e., water). The human datasets 1 and 2 contained 814 and 815 spectra, while the bovine dataset contained 396 spectra. A pure water spectrum was used as a reference spectrum in the MSC approach. A threshold for the root mean square error (RMSE) was used to separate cartilage from water spectra for broadband and the sparse spectral data. Additionally, standard noise-to-ratio and principle component analysis were applied on broadband spectra. The fully automated MSC preclassification approach, using water as reference spectrum, performed as well as the manual visual inspection. Moreover, it enabled not only separation of cartilage from water spectra in broadband spectral datasets, but also in sparse datasets where manual visual inspection cannot be applied.
    MeSH term(s) Animals ; Cattle ; Humans ; Light ; Principal Component Analysis ; Spectroscopy, Fourier Transform Infrared/methods ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2022-04-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27072298
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    Zs.MO 81: Show issues

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  5. Article ; Online: Optimizing extraction solvents for deoxynivalenol analysis in maize

    Femenias, Antoni / Fomina, Polina / Tafintseva, Valeria / Freitag, Stephan / Shapaval, Volha / Sulyok, Michael / Zimmermann, Boris / Marín, Sonia / Krska, Rudolf / Kohler, Achim / Mizaikoff, Boris

    Analytical methods : advancing methods and applications

    2022  Volume 15, Issue 1, Page(s) 36–47

    Abstract: Farmers, cereal suppliers and processors demand rapid techniques for the assessment of mould-associated contamination. Deoxynivalenol (DON) is among the most ... ...

    Abstract Farmers, cereal suppliers and processors demand rapid techniques for the assessment of mould-associated contamination. Deoxynivalenol (DON) is among the most important
    MeSH term(s) Animals ; Humans ; Zea mays/chemistry ; Zea mays/microbiology ; Chromatography, Liquid ; Food Contamination/analysis ; Solvents ; Methanol/analysis ; Chemometrics ; Tandem Mass Spectrometry ; Spectrophotometry, Infrared/methods ; Water
    Chemical Substances deoxynivalenol (JT37HYP23V) ; Solvents ; Methanol (Y4S76JWI15) ; Water (059QF0KO0R)
    Language English
    Publishing date 2022-12-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2515210-5
    ISSN 1759-9679 ; 1759-9660
    ISSN (online) 1759-9679
    ISSN 1759-9660
    DOI 10.1039/d2ay00995a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Preprocessing Strategies for Sparse Infrared Spectroscopy: A Case Study on Cartilage Diagnostics.

    Tafintseva, Valeria / Lintvedt, Tiril Aurora / Solheim, Johanne Heitmann / Zimmermann, Boris / Rehman, Hafeez Ur / Virtanen, Vesa / Shaikh, Rubina / Nippolainen, Ervin / Afara, Isaac / Saarakkala, Simo / Rieppo, Lassi / Krebs, Patrick / Fomina, Polina / Mizaikoff, Boris / Kohler, Achim

    Molecules (Basel, Switzerland)

    2022  Volume 27, Issue 3

    Abstract: The aim of the study was to optimize preprocessing of sparse infrared spectral data. The sparse data were obtained by reducing broadband Fourier transform infrared attenuated total reflectance spectra of bovine and human cartilage, as well as of ... ...

    Abstract The aim of the study was to optimize preprocessing of sparse infrared spectral data. The sparse data were obtained by reducing broadband Fourier transform infrared attenuated total reflectance spectra of bovine and human cartilage, as well as of simulated spectral data, comprising several thousand spectral variables into datasets comprising only seven spectral variables. Different preprocessing approaches were compared, including simple baseline correction and normalization procedures, and model-based preprocessing, such as multiplicative signal correction (MSC). The optimal preprocessing was selected based on the quality of classification models established by partial least squares discriminant analysis for discriminating healthy and damaged cartilage samples. The best results for the sparse data were obtained by preprocessing using a baseline offset correction at 1800 cm
    MeSH term(s) Animals ; Cartilage/chemistry ; Cattle ; Female ; Humans ; Male ; Signal Processing, Computer-Assisted ; Spectroscopy, Fourier Transform Infrared
    Language English
    Publishing date 2022-01-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27030873
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    In stock of ZB MED Cologne/Königswinter

    Zs.MO 81: Show issues

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  7. Article: Reaktsiia Takata-Ara u bol'nykh pri septicheskoi poslerodovoi infektsii.

    FOMINA, P I

    Akusherstvo i ginekologiia

    1954  Volume 2, Page(s) 85–87

    Title translation Takata-Ara reaction in puerperal infection.
    MeSH term(s) Female ; Humans ; Liver Function Tests ; Pregnancy ; Puerperal Infection/physiology
    Language Undetermined
    Publishing date 1954-03
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 127158-1
    ISSN 0300-9092 ; 0002-3906
    ISSN 0300-9092 ; 0002-3906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 66: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Izmeneniia antitoksicheskoi funktsii pecheni pri septicheskikh poslerodovykh zabolevaniiakh.

    FOMINA, P I

    Akusherstvo i ginekologiia

    1954  Volume 3, Page(s) 77–78

    Title translation Modification of antitoxic functions of the liver in septic diseases in puerperium.
    MeSH term(s) Female ; Humans ; Liver ; Liver Function Tests ; Postpartum Period ; Pregnancy ; Puerperal Infection/physiology
    Language Undetermined
    Publishing date 1954-05
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 127158-1
    ISSN 0300-9092 ; 0002-3906
    ISSN 0300-9092 ; 0002-3906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 66: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book: Moĭ opyt raboty zootekhnikom

    Fomina, P. P

    1955  

    Title translation Being a cattle farm manager.
    Keywords Dairy cattle. ; Collective farms
    Language Russian
    Size 1 folder
    Publisher Ministerstvo sel'skogo khozi︠a︡ĭstva SSSR
    Publishing place Moskva
    Document type Book
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Immunohistochemical Profile of Mucins and their Expression in Precancerous Changes of the Stomach

    Sergii V. Vernygorodskyi, PhD¹ / Lyudmila V. Fomina, PhD, ScD¹ / Maksim V. Mnikhovich, PhD² / Nila A. Kaminska PhD¹ / Galina V. Datsenko, PhD¹ / Arthur M. Berezovskiy, PhD¹ / Olena M. Shapoval, PhD¹ / Olena I. Bashynska, PhD¹ / Natalia V. Belik, PhD¹

    International Journal of Biomedicine, Vol 3, Iss 2, Pp 115-

    2013  Volume 118

    Abstract: The aim of this study was to assess the profile of mucins (MUC1, MUC2, MUC5AC) in the intestinal metaplasia (IM) of the gastric mucosa through the immunohistochemical method. Methods: To identify the metaplastic areas in the gastric mucosa, ... ...

    Abstract The aim of this study was to assess the profile of mucins (MUC1, MUC2, MUC5AC) in the intestinal metaplasia (IM) of the gastric mucosa through the immunohistochemical method. Methods: To identify the metaplastic areas in the gastric mucosa, chromoendoscopy was employed using 0.5% solution of methylene blue. The expression of the profile of the mucins was determined using immunohistochemistry with MUC1, MUC5AC, and MUC2 antibodies (clone Ma695, clone CLH2, Ccp58 and CLH5, "Novocastra "Great Britain). Results: In the regions adjacent to the adenocarcinoma and neoplastic modified cells, a visible weak expression of MUC2 and MUC5AC was observed. In the case of complete IM, a visibly maximum MUC2 expression was observed in the goblet cells; thus, the MUC5AC, MUC1, and MUC6 marking were absent in the columnar epitheliocytes with the brush border. In the case of incomplete IM, along with the positive MUC2 markings of the goblet cells, the presence of gastric mucin (MUC5AC) has been observed in 25% of such patients with chronic atrophic gastritis (CAG) having incomplete IM; however, in the columnar epitheliocytes the characteristic occurrence of gastric mucin (MUC5AC) was observed in 100% of the patients while a small amount of MUC2 was recorded in 15% of patients. Conclusion: The MUC5AC expression of the gastric mucins in the columnar epithelial cells and the goblet exocrinocytes marks the formation of the gastrointestinal phenotype viz., incomplete intestinal metaplasia, along with the simultaneous production of the MUC2 by the goblet cells. The decrease with further loss of the protective MUC5AC production by the columnar epithelial cells and goblet exocrinocytes that were found in the regions of severe dysplasia and IM, adjacent to the neoplastic altered cells, may serve as additional criteria of early malignancy of the gastric mucosa.
    Keywords mucins ; precancerous changes of the gastric mucosa. ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2013-06-01T00:00:00Z
    Publisher International Medical Research and Development Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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