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  1. Article: Neurothekeoma in the Axilla Causing Persistent Shoulder Pain: Case Report.

    Silva, Christine Maria Muniz / Fontenele, João Paulo Uchoa / Lopes, Jailson Rodrigues / de Brito, Gabriella Cristina Coelho / Teixeira, Manuel Joaquim Diógenes / Rocha, Francisco Airton Castro

    Revista brasileira de ortopedia

    2020  Volume 55, Issue 6, Page(s) 804–807

    Abstract: Neurothekeomas, also known as neural sheath myxomas, are rare benign tumors of the neural sheath affecting most commonly the head, arms and shoulder of women in their ... ...

    Abstract Neurothekeomas, also known as neural sheath myxomas, are rare benign tumors of the neural sheath affecting most commonly the head, arms and shoulder of women in their 2
    Language English
    Publishing date 2020-09-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2411301-3
    ISSN 1982-4378 ; 0102-3616
    ISSN (online) 1982-4378
    ISSN 0102-3616
    DOI 10.1055/s-0040-1712135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Misdiagnosis of Paget's Disease of Bone in a Congenital Generalized Lipodystrophy Patient: Case Report.

    Freire, Erika Bastos Lima / Madeira, Mayara Ponte / Lima, Grayce Ellen da Cruz Paiva / Fernandes, Virginia Oliveira / Aguiar, Lindenberg Barbosa / Fontenele, João Paulo Uchoa / Montenegro, Ana Paula Dias Rangel / Marques, Thyciara Fontenele / Ozório, Renan Galvão / d'Alva, Catarina Brasil / Montenegro, Renan Magalhães

    Frontiers in endocrinology

    2021  Volume 12, Page(s) 683697

    Abstract: Paget's disease of bone (PDB) is a common skeleton disorder in which the diagnosis is suggested by radiological analyses. Congenital generalized lipodystrophy (CGL) is a rare, but a radiologic differential diagnosis of Paget's disease. Patients present ... ...

    Abstract Paget's disease of bone (PDB) is a common skeleton disorder in which the diagnosis is suggested by radiological analyses. Congenital generalized lipodystrophy (CGL) is a rare, but a radiologic differential diagnosis of Paget's disease. Patients present total or almost total lack of subcutaneous adipose tissue, leptin deficiency, and precocious ectopic lipid accumulation, which lead to intense insulin resistance, poorly controlled diabetes mellitus, and hypertriglyceridemia. CGL subtypes 1 and 2 present sclerosis and osteolytic lesions that can resemble "pagetic" lesions. The clinical correlation is, therefore, essential. We report a CGL patient with bone lesions in which the radiographic findings led to a misdiagnosis of PDB. This case report brings awareness to CGL, a life-threating condition. Its early recognition is essential to avoid clinical complications and premature death. Therefore, it is important to consider CGL as PDB's differential diagnosis, especially in countries with high prevalence of this rare disease, such as Brazil.
    MeSH term(s) Adult ; Diagnosis, Differential ; Diagnostic Errors ; Humans ; Lipodystrophy, Congenital Generalized/diagnosis ; Male ; Osteitis Deformans/diagnosis
    Language English
    Publishing date 2021-06-28
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2021.683697
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Neurotecoma na axila causando dor persistente no ombro: Relato de caso

    Silva, Christine Maria Muniz / Fontenele, João Paulo Uchoa / Lopes, Jailson Rodrigues / de Brito, Gabriella Cristina Coelho / Teixeira, Manuel Joaquim Diógenes / Rocha, Francisco Airton Castro

    Revista Brasileira de Ortopedia

    2020  Volume 55, Issue 06, Page(s) 804–807

    Abstract: Neurotecomas, também conhecidos como mixomas da bainha neural, são tumores benignos raros da bainha neural afetando mais comumente a cabeça, braços e ombros de mulheres entre 20 e 40 anos de idade. Devido à baixa prevalência e quadro clínico mal definido, ...

    Abstract Neurotecomas, também conhecidos como mixomas da bainha neural, são tumores benignos raros da bainha neural afetando mais comumente a cabeça, braços e ombros de mulheres entre 20 e 40 anos de idade. Devido à baixa prevalência e quadro clínico mal definido, essas lesões são raramente consideradas no diagnóstico diferencial de tumores cutâneos. Relatamos o caso de uma mulher de 24 anos de idade que procurou atendimento em 2016 relatando dor moderada por mais de um ano e limitação dos movimentos do ombro esquerdo. Ao exame, foi constatada restrição da mobilidade dessa articulação e uma ressonância magnética revelou imagem multilobular com aumento de sinal em T2 na região quadrilateral, aparentando invasão da região cortical do úmero subjacente. A histopatologia de uma biópsia incisional mostrou lesão composta por tecido conjuntivo frouxo, sem sinais de invasão, figuras de mitose ou atipias. Foi realizada excisão completa da lesão e o diagnóstico de neurotecoma foi confirmado após análise histopatológica que incluiu painel imunohistoquímico. À revisão de 18 meses, a paciente estava assintomática com recuperação completa do movimento e sem evidência de recidiva da lesão.

    Neurothekeomas, also known as neural sheath myxomas, are rare benign tumors of the neural sheath affecting most commonly the head, arms and shoulder of women in their 2 nd and 3 rd decades of life. Due to the low prevalence and undefined clinical picture, they are hardly considered in the initial differential diagnosis of skin tumors. We report the case of a 24 year-old woman who was seen in 2016 reporting > 1 year of moderate pain and limited mobility of her left shoulder. Clinical evaluation revealed restricted mobility of the affected shoulder and nuclear magnetic resonance imaging showed a T2-weighted contrast-enhanced multilobular mass in the quadrilateral area apparently invading the adjacent humeral cortical region. Histopathology of a needle sample material revealed loose fibroconnective tissue with no signs of invasion, mitosis or atypical figures. Successful surgical excision was performed and the diagnosis of neurothekeoma was confirmed after detailed histopathology, including immunohistochemistry. The patient was asymptomatic at 18 months of follow-up, with full recovery of shoulder movement and no signs of relapse.
    Keywords neurotecoma ; ombro ; tumor ; neurothekeoma ; shoulder ; tumors
    Language Portuguese
    Publishing date 2020-09-22
    Publisher Thieme Revinter Publicações Ltda.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2411301-3
    ISSN 1982-4378 ; 0102-3616 ; 1982-4378
    ISSN (online) 1982-4378
    ISSN 0102-3616 ; 1982-4378
    DOI 10.1055/s-0040-1712135
    Database Thieme publisher's database

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  4. Article: Diffuse Gastric Cancer During Pregnancy: Report of a Rare Association.

    Barbosa, Orivaldo Alves / de Souza, Anna Dorotheia Bezerra / Moura, Mayna Raphaela de Carvalho / Junior, Elson Jose de Almeida / Fontenele, Joao Paulo Uchoa / Chaves, Fabio de Figuereido / Correia, Jose Walter

    World journal of oncology

    2015  Volume 6, Issue 5, Page(s) 456–458

    Abstract: Gastric cancer during pregnancy is a rare event and difficult to diagnose, as the symptoms can be confused with those of an ordinary pregnancy. We report a case of a 25-year-old patient with a 29-week gestation, with asthenia complaint, vomiting and ... ...

    Abstract Gastric cancer during pregnancy is a rare event and difficult to diagnose, as the symptoms can be confused with those of an ordinary pregnancy. We report a case of a 25-year-old patient with a 29-week gestation, with asthenia complaint, vomiting and weight loss. During the investigation of wasting syndrome endoscopy was performed with infiltrative ulcerative lesions in pre-pyloric region with biopsy revealing carcinoma with signet ring, undifferentiated type. It was held on a strict control of fetal vitality, and pregnancy was interrupted via the abdominal delivery at 34 weeks. Soon after the cesarean section was performed, exploratory laparotomy was performed to perform inventory of the abdominal cavity, being observed the presence of carcinomatous implants in the peritoneum. In the face of irresectability clinical conduct was adopted and the patient was sent to chemotherapy, ensuring nutrition via a jejunostomy. The article reviews the gastric carcinoma association with pregnancy, discussing the initiation of treatment and continuity of pregnancy.
    Language English
    Publishing date 2015-10-26
    Publishing country Canada
    Document type Case Reports
    ZDB-ID 2548989-6
    ISSN 1920-454X ; 1920-4531
    ISSN (online) 1920-454X
    ISSN 1920-4531
    DOI 10.14740/wjon945w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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