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  1. Book ; Online: "No Words for Feelings, yet!". Exploring Alexithymia, Disorder of Affect Regulation and "Mind-Body" Connection

    De Berardis, Domenico / Fornaro, Michele / Orsolini, Laura

    2020  

    Keywords Medicine ; Psychiatry ; Alexithymia ; Affect Regulation ; Neurobiology ; Interventions ; Treatment Models
    Size 1 electronic resource (153 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231352
    ISBN 9782889660346 ; 2889660346
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: There are no "side" effects, just "core" effects of antipsychotic pharmacotherapy.

    Fornaro, Michele

    Acta psychiatrica Scandinavica

    2021  Volume 143, Issue 2, Page(s) 99–100

    MeSH term(s) Antipsychotic Agents/adverse effects ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Schizophrenia/drug therapy
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 2021-01-16
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 103-x
    ISSN 1600-0447 ; 0001-690X
    ISSN (online) 1600-0447
    ISSN 0001-690X
    DOI 10.1111/acps.13271
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Editorial: Comorbidity in bipolar disorder and schizophrenia, volume III.

    Martinotti, Giovanni / Fornaro, Michele / De Berardis, Domenico

    Frontiers in psychiatry

    2024  Volume 14, Page(s) 1356817

    Language English
    Publishing date 2024-01-09
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1356817
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reply to Dr. Gentili' "Analysis of tolerance to antidepressant drugs in FDA Adverse Event Reporting System".

    Fornaro, Michele

    Pharmacological research

    2018  Volume 141, Page(s) 618

    MeSH term(s) Adverse Drug Reaction Reporting Systems ; Antidepressive Agents ; Depressive Disorder, Major ; Humans
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2018-12-15
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1003347-6
    ISSN 1096-1186 ; 0031-6989 ; 1043-6618
    ISSN (online) 1096-1186
    ISSN 0031-6989 ; 1043-6618
    DOI 10.1016/j.phrs.2018.12.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reply to Dr. Sharma' "Understanding antidepressant tachyphylaxis".

    Fornaro, Michele

    Pharmacological research

    2018  Volume 141, Page(s) 620

    MeSH term(s) Antidepressive Agents ; Depressive Disorder, Major ; Humans ; Tachyphylaxis
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2018-11-22
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1003347-6
    ISSN 1096-1186 ; 0031-6989 ; 1043-6618
    ISSN (online) 1096-1186
    ISSN 0031-6989 ; 1043-6618
    DOI 10.1016/j.phrs.2018.11.025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Choosing the appropriate pharmacotherapy for obsessive-compulsive disorder in adult patients with comorbid anxiety disorders: clinical and nosological considerations.

    Fornaro, Michele

    Expert opinion on pharmacotherapy

    2018  Volume 20, Issue 2, Page(s) 123–126

    Language English
    Publishing date 2018-11-29
    Publishing country England
    Document type Editorial
    ZDB-ID 2001535-5
    ISSN 1744-7666 ; 1465-6566
    ISSN (online) 1744-7666
    ISSN 1465-6566
    DOI 10.1080/14656566.2018.1549225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Editorial: Comorbidity in bipolar disorder, volume II.

    De Berardis, Domenico / Fornaro, Michele / Carmassi, Claudia

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1115357

    Language English
    Publishing date 2023-02-28
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1115357
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An update on the pharmacotherapeutic strategies for the treatment of dysthymic disorder: a systematic review.

    Quagliato, Laiana A / Primavera, Diego / Fornaro, Michele / Preti, Antonio / Carta, Mauro G / Nardi, Antonio E

    Expert opinion on pharmacotherapy

    2024  Volume 24, Issue 18, Page(s) 2035–2040

    Abstract: Introduction: Longer treatment times, more comorbidity, more severe impairments in social, psychological, and emotional functioning, increased healthcare use, and more hospitalizations are all factors that are related to dysthymia. Given the significant ...

    Abstract Introduction: Longer treatment times, more comorbidity, more severe impairments in social, psychological, and emotional functioning, increased healthcare use, and more hospitalizations are all factors that are related to dysthymia. Given the significant prevalence of dysthymia (including persistent depressive disorder) worldwide, its comorbidity with several mental disorders, and the detrimental effects of these comorbidities, it is important to conduct a systematic review to compare the effects of pharmacological acute and maintenance treatments for dysthymia with placebo and standard care in the last 10 years, based on the publication of DSM5.
    Areas covered: This systematic review was performed according to PRISMA guidelines. Databases, including PubMed and Cochrane Central Register of Controlled Trials, were searched to assess the effects of pharmacological acute and maintenance treatments for dysthymia in comparison with placebo and treatment as usual.
    Expert opinion: Our review shows that SSRIs and SNRIs present efficacy for dysthymia treatment, and L-Acetylcarnitine should be investigated further for this condition in elderly patients. The comparison of antidepressant medication versus placebo showed coherent results based on three studies favoring pharmacotherapy as an effective treatment for participants with dysthymia. However, the scarcity of research on continuation and maintenance therapy in people with dysthymia highlights the need for more primary research.
    MeSH term(s) Aged ; Humans ; Antidepressive Agents/therapeutic use ; Comorbidity ; Depressive Disorder/drug therapy ; Dysthymic Disorder/drug therapy ; Selective Serotonin Reuptake Inhibitors/therapeutic use ; Serotonin and Noradrenaline Reuptake Inhibitors/therapeutic use
    Chemical Substances Antidepressive Agents ; Selective Serotonin Reuptake Inhibitors ; Serotonin and Noradrenaline Reuptake Inhibitors
    Language English
    Publishing date 2024-01-05
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 2001535-5
    ISSN 1744-7666 ; 1465-6566
    ISSN (online) 1744-7666
    ISSN 1465-6566
    DOI 10.1080/14656566.2023.2265809
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A bitter pill to swallow? Impact of affective temperaments on treatment adherence: a systematic review and meta-analysis.

    Szabo, Georgina / Fornaro, Michele / Dome, Peter / Varbiro, Szabolcs / Gonda, Xenia

    Translational psychiatry

    2022  Volume 12, Issue 1, Page(s) 360

    Abstract: Background: Predominant affective temperament may affect adherence to prescribed pharmacotherapeutic interventions, warranting systematic review and meta-analysis.: Methods: The Scopus, Web of Science, PubMed, and OVID MedLine databases were inquired ...

    Abstract Background: Predominant affective temperament may affect adherence to prescribed pharmacotherapeutic interventions, warranting systematic review and meta-analysis.
    Methods: The Scopus, Web of Science, PubMed, and OVID MedLine databases were inquired since inception up to 31st of March 2022 for records of any study design documenting quantitative evidence about affective temperaments as measured by the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego (TEMPS-A) questionnaire and treatment adherence measured by the means of major rating scales on the matter. People with low vs. high levels of treatment adherence, matched for otherwise clinically relevant variables, were deemed as cases and controls, respectively, using standardized mean differences (SMDs) in pertinent scores under random-effects meta-analysis.
    Results: Nine studies encompassing 1138 subjects pointed towards significantly higher cyclothymic (SMD = -0.872; CI: [-1.51 to -0.24]; p = 0.007), irritable (SMD = -0.773; CI: [-1.17 to -0.37]; p < 0.001) and depressive (SMD = -0.758; CI: [-1.38 to -0.14]; p = 0.017) TEMPS-A scores both for psychiatric and nonpsychiatric samples with poorer adherence.
    Limitations: Intrinsic limitations of the present report include the heterogeneity of the operational definitions documented across different primary studies, which nonetheless reported on the sole medication-treatment adherence, thus limiting the generalizability of the present findings based on a handful of comparisons.
    Conclusions: Though further primary studies need to systematically account for different clinical and psychosocial moderators across different clinical populations and operational definitions, cyclothymic, depressive, and irritable temperament scores may nonetheless predict treatment adherence and, thus, overall treatment outcomes.
    MeSH term(s) Humans ; Irritable Mood ; Personality Inventory ; Surveys and Questionnaires ; Temperament ; Treatment Adherence and Compliance
    Language English
    Publishing date 2022-09-02
    Publishing country United States
    Document type Meta-Analysis ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2609311-X
    ISSN 2158-3188 ; 2158-3188
    ISSN (online) 2158-3188
    ISSN 2158-3188
    DOI 10.1038/s41398-022-02129-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Dynamic Environmental Physical Cues Activate Mechanosensitive Responses in the Repair Schwann Cell Phenotype.

    Fornaro, Michele / Marcus, Dominic / Rattin, Jacob / Goral, Joanna

    Cells

    2021  Volume 10, Issue 2

    Abstract: Schwann cells plastically change in response to nerve injury to become a newly reconfigured repair phenotype. This cell is equipped to sense and interact with the evolving and unusual physical conditions characterizing the injured nerve environment and ... ...

    Abstract Schwann cells plastically change in response to nerve injury to become a newly reconfigured repair phenotype. This cell is equipped to sense and interact with the evolving and unusual physical conditions characterizing the injured nerve environment and activate intracellular adaptive reprogramming as a consequence of external stimuli. Summarizing the literature contributions on this matter, this review is aimed at highlighting the importance of the environmental cues of the regenerating nerve as key factors to induce morphological and functional changes in the Schwann cell population. We identified four different microenvironments characterized by physical cues the Schwann cells sense via interposition of the extracellular matrix. We discussed how the physical cues of the microenvironment initiate changes in Schwann cell behavior, from wrapping the axon to becoming a multifunctional denervated repair cell and back to reestablishing contact with regenerated axons.
    MeSH term(s) Cues ; Humans ; Myelin Sheath/metabolism ; Nerve Regeneration/physiology ; Peripheral Nerve Injuries/metabolism ; Phenotype ; Schwann Cells/cytology
    Language English
    Publishing date 2021-02-17
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells10020425
    Database MEDical Literature Analysis and Retrieval System OnLINE

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