Artikel ; Online: A Case Report of Acute Renal Failure as a Result of Light-Chain-Mediated Acute Tubular Interstitial Nephritis in a 30-Year-Old Combat Veteran.
2017 Band 182, Heft 11, Seite(n) e2099–e2103
Abstract: We present a 30-year-old combat veteran with an unclear exposure history, with multiple deployments who was later diagnosed with acute renal failure as a result of light-chain deposition disease. Despite a drastic decline in kappa light chains following ... ...
Abstract | We present a 30-year-old combat veteran with an unclear exposure history, with multiple deployments who was later diagnosed with acute renal failure as a result of light-chain deposition disease. Despite a drastic decline in kappa light chains following chemotherapy; his renal function worsened, and he progressed to end-stage renal disease, requiring hemodialysis. Light-chain-mediated acute tubular interstitial nephritis is an uncommon type of monoclonal gammopathy of renal significance presenting with acute renal failure without significant glomerular disease. Our case illustrates that light-chain-mediated acute tubular interstitial nephritis may present clinically like acute interstitial nephritis and that renal biopsy is critical for diagnosis. We also explore possible links between various environmental and occupational exposures that could have precipitated his disease process at such a young age. |
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Mesh-Begriff(e) | Acute Kidney Injury/etiology ; Adult ; African Americans ; Hepatitis C ; Humans ; Immunoglobulins/deficiency ; Immunologic Deficiency Syndromes/complications ; Kidney/anatomy & histology ; Kidney/injuries ; Male ; Nephritis, Interstitial/complications ; Risk Factors ; United States ; United States Department of Veterans Affairs/organization & administration ; Veterans |
Chemische Substanzen | Immunoglobulins |
Sprache | Englisch |
Erscheinungsdatum | 2017-11-02 |
Erscheinungsland | England |
Dokumenttyp | Case Reports ; Journal Article |
ZDB-ID | 391061-1 |
ISSN | 1930-613X ; 0026-4075 |
ISSN (online) | 1930-613X |
ISSN | 0026-4075 |
DOI | 10.7205/MILMED-D-17-00164 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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