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  1. AU="Forte, Florence"
  2. AU="Anika Nier"
  3. AU="Bar, Adi"
  4. AU="Alvarado Pinedo, María F."
  5. AU="Scarlett, Garry"
  6. AU="Carlos G. Vanoye"
  7. AU=Lohrmann Jens
  8. AU="Petersen, Moritz"
  9. AU="Giovanni, L."
  10. AU="Liu, Xingzheng"
  11. AU="Głód, Mateusz"
  12. AU=Teo Kelvin Yi Chong
  13. AU="Khatmi, Aysan"
  14. AU="Erculiani, M"
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  16. AU="Lisnic, Vanda Juranic"
  17. AU="Seabloom, Eric W"
  18. AU="Odvina, Clarita V"
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  21. AU="Nelson, Warrick"
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  24. AU="Barbera, Lauren"
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  26. AU="Shan, Qing-Hua"
  27. AU="Starko, S"
  28. AU="Lievre, Loïc"
  29. AU=Cammack N
  30. AU="Xia, Qin"
  31. AU="Ong, Ju Lynn"
  32. AU="Cullin, Christophe"
  33. AU="Georg K.S. Andersson"
  34. AU="Jeannel, Gaël-François"
  35. AU="Stuart Woods"
  36. AU="Shchegolev, A."
  37. AU="Nadeau, Pierre-Louis"
  38. AU="Gordon, David E A"
  39. AU="Shahid Mahmood"
  40. AU="Rosenblatt, Karin"
  41. AU="Dasgupta, Suvankar"
  42. AU=Nguyen Sylvain AU=Nguyen Sylvain

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  1. Artikel ; Online: Piège diagnostique : neurotoxicité au lithium avec lithémie normale.

    Tiv, Hugo / Vandelaer, Antoine / Delanaye, Pierre / Forte, Florence / Bouquegneau, Antoine

    Nephrologie & therapeutique

    2022  Band 18, Heft 7, Seite(n) 650–654

    Abstract: We describe here the case of a 54-year-old bipolar woman, followed in psychiatry and treated with lithium and a selective serotonin reuptake inhibitor (escitalopram) and lamotrigine, presenting a lithium poisoning with an altered state of consciousness ... ...

    Titelübersetzung Diagnostic trap: Lithium neurotoxicity with normal lithemia.
    Abstract We describe here the case of a 54-year-old bipolar woman, followed in psychiatry and treated with lithium and a selective serotonin reuptake inhibitor (escitalopram) and lamotrigine, presenting a lithium poisoning with an altered state of consciousness caused by a supposed mismanagement of her treatment. Lithium poisoning was suggested based on neurological clinical features, but the blood test brought out a lithium concentration within the therapeutic values at 1,2 mmol/L (N: 0,6-1,2 mmol/L). The classic biological complications related to lithium poisoning (hypercalcemia, diabetes insipidus) confirmed the diagnosis. The patient has been transferred to our nephrology department where she got two hemodialysis sessions conducting to clinical and biological improvement, confirming the diagnosis of lithium poisoning despite the normal blood levels. Later, she was transferred to the psychiatry department for follow-up and for treatment adjustment.
    Sprache Französisch
    Erscheinungsdatum 2022-09-23
    Erscheinungsland France
    Dokumenttyp English Abstract ; Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1016/j.nephro.2022.07.398
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Neuronal surface antibody-mediated encephalopathy as manifestation of chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.

    Pirotte, Michelle / Forte, Florence / Lutteri, Laurence / Willems, Evelyne / Duran, Unal / Belle, Ludovic / Baron, Frédéric / Beguin, Yves / Maquet, Pierre / Bodart, Olivier / Servais, Sophie

    Journal of neuroimmunology

    2018  Band 323, Seite(n) 115–118

    Abstract: Although it remained controversial for a long time, central nervous system (CNS) involvement of graft-versus-host disease (GVHD) is now becoming recognized as a real nosological entity. Previous case reports have suggested heterogeneous clinical ... ...

    Abstract Although it remained controversial for a long time, central nervous system (CNS) involvement of graft-versus-host disease (GVHD) is now becoming recognized as a real nosological entity. Previous case reports have suggested heterogeneous clinical presentations and it is not excluded that the whole spectrum of manifestations has not yet been fully described. Here, we report the case of a 58-year-old man with chronic GVHD who developed a rapidly ingravescent encephalopathy. There was no evidence for CNS immune-mediated lesions on conventional imaging nor for cellular infiltration in the cerebrospinal fluid. Serum analyses revealed the presence of anti-neuronal antibodies directed against anti-contactin-associated protein 2 (anti-Caspr2), a protein associated with voltage-gated potassium neuronal channels. Functional imaging with 2-deoxy-2-[fluorine-18] fluoro- d-glucose integrated with computed tomography (18F-FDG PET-CT) demonstrated diffuse cortical and subcortical hypometabolism. The patient was treated with a combination of immunosuppressive agents (corticosteroids, cyclophosphamide and rituximab) and progressively recovered normal neurocognitive functions. Taken together, these data suggest that CNS-GVHD may manifest as a reversible antibody-mediated functional encephalopathy. This report suggests for the first time the interest of screening for anti-neuronal antibodies and functional imaging with brain 18F-FDG PET-CT in diagnosing this severe complication of allogeneic hematopoietic cell transplantation (alloHSCT).
    Mesh-Begriff(e) Antibodies, Antineutrophil Cytoplasmic/cerebrospinal fluid ; Brain Diseases/cerebrospinal fluid ; Brain Diseases/diagnostic imaging ; Brain Diseases/etiology ; Chronic Disease ; Graft vs Host Disease/cerebrospinal fluid ; Graft vs Host Disease/diagnostic imaging ; Graft vs Host Disease/etiology ; Hematopoietic Stem Cell Transplantation/adverse effects ; Hematopoietic Stem Cell Transplantation/trends ; Humans ; Male ; Middle Aged ; Transplantation, Homologous/adverse effects ; Transplantation, Homologous/trends
    Chemische Substanzen Antibodies, Antineutrophil Cytoplasmic
    Sprache Englisch
    Erscheinungsdatum 2018-08-07
    Erscheinungsland Netherlands
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 8335-5
    ISSN 1872-8421 ; 0165-5728
    ISSN (online) 1872-8421
    ISSN 0165-5728
    DOI 10.1016/j.jneuroim.2018.08.003
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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