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  1. Article ; Online: Bhlhe40 limits early IL-10 production from CD4

    O'Neal, Kara A / Zeltner, Sheldon L / Foscue, Camille L / Stumhofer, Jason S

    Infection and immunity

    2023  Volume 91, Issue 11, Page(s) e0036723

    Abstract: The cytokine IL-10 suppresses T-cell-mediated immunity, which is required to control infection ... ...

    Abstract The cytokine IL-10 suppresses T-cell-mediated immunity, which is required to control infection with
    MeSH term(s) Mice ; Animals ; Interleukin-10 ; Plasmodium yoelii ; Cytokines ; Interferon-gamma ; T-Lymphocytes, Regulatory/metabolism ; Mice, Inbred C57BL ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Basic Helix-Loop-Helix Transcription Factors/genetics
    Chemical Substances Interleukin-10 (130068-27-8) ; Cytokines ; Interferon-gamma (82115-62-6) ; Bhlhe40 protein, mouse ; Homeodomain Proteins ; Basic Helix-Loop-Helix Transcription Factors
    Language English
    Publishing date 2023-10-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/iai.00367-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection.

    O'Neal, Kara A / Latham, Leah E / Ntirandekura, Enatha / Foscue, Camille L / Stumhofer, Jason S

    Infection and immunity

    2022  Volume 90, Issue 3, Page(s) e0046821

    Abstract: Inducible T cell costimulator (ICOS) plays a key role in the differentiation and maintenance of follicular helper T (Tfh) cells and, thus, germinal center (GC) formation. Previously, our laboratory showed in a Plasmodium chabaudi infection model ... ...

    Abstract Inducible T cell costimulator (ICOS) plays a key role in the differentiation and maintenance of follicular helper T (Tfh) cells and, thus, germinal center (GC) formation. Previously, our laboratory showed in a Plasmodium chabaudi infection model that
    MeSH term(s) Animals ; B-Lymphocytes ; Germinal Center/metabolism ; Inducible T-Cell Co-Stimulator Protein/metabolism ; Malaria ; Mice ; Mice, Inbred C57BL ; Plasmodium yoelii ; Spleen/metabolism ; T-Lymphocytes, Helper-Inducer
    Chemical Substances Icos protein, mouse ; Inducible T-Cell Co-Stimulator Protein
    Language English
    Publishing date 2022-01-10
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 218698-6
    ISSN 1098-5522 ; 0019-9567
    ISSN (online) 1098-5522
    ISSN 0019-9567
    DOI 10.1128/IAI.00468-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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