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  1. Article ; Online: A Two-Phase Stochastic Dynamic Model for COVID-19 Mid-Term Policy Recommendations in Greece: A Pathway towards Mass Vaccination.

    Rachaniotis, Nikolaos P / Dasaklis, Thomas K / Fotopoulos, Filippos / Tinios, Platon

    International journal of environmental research and public health

    2021  Volume 18, Issue 5

    Abstract: From 7 November 2020, Greece adopted a second nationwide lockdown policy to mitigate the transmission of SARS-CoV-2 (the first took place from 23 March to 4 May 2020), just as the second wave of COVID-19 was advancing, as did other European countries. To ...

    Abstract From 7 November 2020, Greece adopted a second nationwide lockdown policy to mitigate the transmission of SARS-CoV-2 (the first took place from 23 March to 4 May 2020), just as the second wave of COVID-19 was advancing, as did other European countries. To secure the full benefits of mass vaccination, which started in early January 2021, it is of utmost importance to complement it with mid-term non-pharmaceutical interventions (NPIs). The objective was to minimize human losses and to limit social and economic costs. In this paper a two-phase stochastic dynamic network compartmental model (a pre-vaccination SEIR until 15 February 2021 and a post-vaccination SVEIR from 15 February 2021 to 30 June 2021) is developed. Three scenarios are assessed for the first phase: (a) A baseline scenario, which lifts the national lockdown and all NPIs in January 2021; (b) a "semi-lockdown" scenario with school opening, partial retail sector operation, universal mask wearing, and social distancing/teleworking in January 2021; and (c) a "rolling lockdown" scenario combining a partial lifting of measures in January 2021 followed by a third nationwide lockdown in February 2021. In the second phase three scenarios with different vaccination rates are assessed. Publicly available data along with some first results of the SHARE COVID-19 survey conducted in Greece are used as input. The results regarding the first phase indicate that the "semi-lockdown" scenario clearly outperforms the third lockdown scenario (5.7% less expected fatalities); the second phase is extremely sensitive on the availability of sufficient vaccine supplies and high vaccination rates.
    MeSH term(s) COVID-19 ; Communicable Disease Control ; Europe ; Greece ; Humans ; Mass Vaccination ; Policy ; SARS-CoV-2
    Language English
    Publishing date 2021-03-03
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph18052497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Is Mandatory Vaccination in Population over 60 Adequate to Control the COVID-19 Pandemic in E.U.?

    Rachaniotis, Nikolaos P / Dasaklis, Thomas K / Fotopoulos, Filippos / Chouzouris, Michalis / Sypsa, Vana / Lyberaki, Antigone / Tinios, Platon

    Vaccines

    2022  Volume 10, Issue 2

    Abstract: Vaccine hesitancy, which potentially leads to the refusal or delayed acceptance of COVID-19 vaccines, is considered a key driver of the increasing death toll from the pandemic in the EU. The European Commission and several member states' governments are ... ...

    Abstract Vaccine hesitancy, which potentially leads to the refusal or delayed acceptance of COVID-19 vaccines, is considered a key driver of the increasing death toll from the pandemic in the EU. The European Commission and several member states' governments are either planning or have already directly or indirectly announced mandatory vaccination for individuals aged over 60, the group which has repeatedly proved to be the most vulnerable. In this paper, an assessment of this strategy's benefits is attempted by deriving a metric for the potential gains of vaccination mandates that can be used to compare EU member states. This is completed by examining the reduction in Standard Expected Years of Life Lost (SEYLL) per person for the EU population over 60 as a function of the member states' vaccination percentage in these ages. The publicly available data and results of the second iteration of the SHARE COVID-19 survey on the acceptance of COVID-19 vaccines, conducted during the summer of 2021, are used as inputs.
    Language English
    Publishing date 2022-02-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines10020329
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A two-phase stochastic dynamic model for COVID-19 mid-term policy recommendations in Greece: a pathway towards mass vaccination

    Rachaniotis, Nikolaos P. / Dasaklis, Tomas K. / Fotopoulos, Filippos / Tinios, Platon

    medRxiv

    Abstract: From November 7th, 2020, Greece adopted a second nationwide lockdown policy to mitigate the transmission of SARS-CoV-2 (the first took place from March 23rd till May 4th, 2020), just as the second wave of COVID-19 was advancing, as did other European ... ...

    Abstract From November 7th, 2020, Greece adopted a second nationwide lockdown policy to mitigate the transmission of SARS-CoV-2 (the first took place from March 23rd till May 4th, 2020), just as the second wave of COVID-19 was advancing, as did other European countries. In the light of the very promising voluntary mass vaccination, which will start in January 2021, it is of utmost importance for the country to plan to complement vaccination with mid-term Non-Pharmaceutical Interventions (NPIs). The objective is to minimize human losses and to limit social and economic costs. In this paper a two-phase stochastic dynamic network compartmental model (a pre-vaccination SEIR until February 15th, 2021 and a post-vaccination SVEIR from February 15th, 2021 to June 30th, 2021) is developed. Three scenarios are assessed in the first phase: (a) a baseline scenario, which lifts the national lockdown and all NPIs on January 2021, (b) a 9semi-lockdown9 scenario with school opening, partial retail sector operation, universal mask wearing and social distancing/teleworking on January 2021 and (c) a 9rolling lockdown9 scenario combining a partial lifting of measures in January 2021 followed by a third imposed nationwide lockdown in February 2021. In the second phase three scenarios with different vaccination rates are assessed. Publicly available data along with some preliminary first results of the SHARE COVID-19 survey conducted in Greece are used as input. The results regarding the first phase indicate that the 9semi-lockdown9 scenario outperforms the third lockdown scenario (5.7% less expected fatalities), whereas in the second phase it is of great importance to ensure a sufficient vaccine supply and high vaccination rates.
    Keywords covid19
    Language English
    Publishing date 2021-01-08
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2021.01.07.21249394
    Database COVID19

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  4. Article ; Online: Is mandatory vaccination in population over 60 adequate to control the COVID-19 pandemic in E.U.?

    Rachaniotis, Nikolaos / Dasaklis, Thomas / Fotopoulos, Filippos / Chouzouris, Michael / Georgiadis, Thomas / Lyberaki, Antigoni / Tinios, Platon

    medRxiv

    Abstract: Vaccine hesitancy, which potentially leads to refusal or delayed acceptance of COVID-19 vaccines, is considered a key driver for the increasing death toll from the pandemic in the E.U.. European Commission and several member states governments are either ...

    Abstract Vaccine hesitancy, which potentially leads to refusal or delayed acceptance of COVID-19 vaccines, is considered a key driver for the increasing death toll from the pandemic in the E.U.. European Commission and several member states governments are either planning or have already directly or indirectly announced mandatory vaccination for individuals aged over 60, the group repeatedly proved to be the most vulnerable. In this paper, an assessment of this strategy benefits is attempted. This is done by examining the reduction of Standard Expected Years of Life Lost (SEYLL) per person of the EU population over 60 as a function of their vaccination percentage. Publicly available data and some first results of the second iteration of the SHARE COVID-19 survey conducted during the summer of 2021 on acceptance of COVID-19 vaccines are used as input.
    Keywords covid19
    Language English
    Publishing date 2022-01-28
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2022.01.25.22269867
    Database COVID19

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