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  1. Article ; Online: Maternal sepsis caused by

    Dunphy, Louise / Polkampali, Mamatha / Simmons, William / Fowler, Grace

    BMJ case reports

    2022  Volume 15, Issue 10

    Abstract: Improving maternal and child health is a global priority. Although infection ... ...

    Abstract Improving maternal and child health is a global priority. Although infection with
    MeSH term(s) Amoxicillin ; Child ; Female ; Humans ; Infant, Newborn ; Listeria monocytogenes ; Listeriosis/complications ; Listeriosis/diagnosis ; Listeriosis/drug therapy ; Obstetric Labor, Premature ; Penicillins ; Placenta ; Pre-Eclampsia ; Pregnancy ; Pregnancy Complications, Infectious/diagnosis ; Sepsis/complications
    Chemical Substances Penicillins ; Amoxicillin (804826J2HU)
    Language English
    Publishing date 2022-10-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2022-249989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Streptococcal pneumonia meningitis as an initial presentation of X-linked agammaglobulinemia: A case report and discussion.

    Kadden, Daniel / Fowler, Grace / Engel, Elissa / Logan, Casey / Marathe, Kalyani / Gosdin, Craig

    Journal of the American College of Emergency Physicians open

    2021  Volume 2, Issue 5, Page(s) e12553

    Abstract: X-linked agammaglobulinemia (XLA) is a primary immunodeficiency caused by mutations in the gene for Bruton's tyrosine ... ...

    Abstract X-linked agammaglobulinemia (XLA) is a primary immunodeficiency caused by mutations in the gene for Bruton's tyrosine kinase
    Language English
    Publishing date 2021-09-17
    Publishing country United States
    Document type Case Reports
    ISSN 2688-1152
    ISSN (online) 2688-1152
    DOI 10.1002/emp2.12553
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: DHA Supplementation Attenuates Inflammation-Associated Gene Expression in the Mammary Gland of Lactating Mothers Who Deliver Preterm.

    Adams, Joselyn M / Valentine, Christina J / Karns, Rebekah A / Rogers, Lynette K / Murase, Masahiko / Fowler, Grace N / Nommsen-Rivers, Laurie A

    The Journal of nutrition

    2022  Volume 152, Issue 6, Page(s) 1404–1414

    Abstract: Background: In a randomized trial of DHA supplementation to lactating mothers who delivered preterm, there were significant increases in DHA status in the mother and her infant.: Objectives: Our objective here was to characterize the mammary gland ... ...

    Abstract Background: In a randomized trial of DHA supplementation to lactating mothers who delivered preterm, there were significant increases in DHA status in the mother and her infant.
    Objectives: Our objective here was to characterize the mammary gland transcriptomes from the above study. We hypothesized that proinflammatory gene expression would be attenuated in the increased DHA group compared with the standard DHA group.
    Methods: In the original trial, mothers delivering at <29 wk gestation at the University of Cincinnati Medical Center and intending to express their milk were randomly assigned to supplementation with 200 mg/d DHA (standard group: STD) or 1000 mg/d DHA (experimental group: EXP) within 7 d of delivery. Here, we conducted RNA-seq transcriptome analysis of n = 5 EXP and n = 4 STD extracellular mammary mRNA samples extracted from the fat layer of milk samples obtained 4 wk postenrollment. Transcripts were assessed for differential expression (false discovery rate adjusted P value <0.05) and clustering between EXP compared with STD groups. Ontological analysis of all differentially expressed genes (DEGs) was performed with Toppcluster.
    Results: There were 409 DEGs. We observed 5 main groups of biological processes that were upregulated, including those associated with improved immune regulation and management of oxidative stress; and 3 main groups of biological processes that were downregulated, including 1 associated with immune dysregulation. For example, we observed upregulation of inflammation-inhibiting genes including NFKB inhibitor alpha (NFKBIA; fold-change (FC), adjusted P value: FC = 1.70, P = 0.007) and interleukin-18 binding protein (IL18BP: FC = 2.2, adjusted P = 0.02); and downregulation of proinflammatory genes including interleukin 7 receptor (IL7R: FC = -1.9, adjusted P = 0.02) and interleukin 1 receptor like 1 (IL1RL1: FC = -13.0, adjusted P = 0.02).
    Conclusions: Increased DHA supplementation during lactation can modulate the expression of inflammation-related genes within the mammary gland. This might translate to milk composition with a more optimal inflammasome profile. Future research with a larger clinical trial and greater interrogation of clinical outcomes is warranted.
    MeSH term(s) Female ; Humans ; Infant ; Infant, Newborn ; Dietary Supplements ; Docosahexaenoic Acids/metabolism ; Docosahexaenoic Acids/therapeutic use ; Gene Expression/drug effects ; Inflammation/diet therapy ; Inflammation/genetics ; Inflammation/metabolism ; Lactation ; Mammary Glands, Human/drug effects ; Mammary Glands, Human/metabolism ; Milk, Human/chemistry ; Mothers
    Chemical Substances Docosahexaenoic Acids (25167-62-8)
    Language English
    Publishing date 2022-02-23
    Publishing country United States
    Document type Clinical Trial ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 218373-0
    ISSN 1541-6100 ; 0022-3166
    ISSN (online) 1541-6100
    ISSN 0022-3166
    DOI 10.1093/jn/nxac043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.205: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Book: Psychodynamic Nursing

    Brown, Martha M. / Fowler, Grace R.

    a biosocial orientation

    1971  

    Author's details Martha Montgomery Brown ; Grace R. Fowler
    Language English
    Size X, 358 S. ; 8-o
    Edition 4. ed.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT008126195
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1972 A 976 order for loan Magazin

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  5. Book: Psychodynamic nursing;

    Brown, Martha Montgomery / Fowler, Grace R

    a biosocial orientation [by] Martha Montgomery Brown [and] Grace R. Fowler

    1971  

    MeSH term(s) Psychiatric Nursing ; Nurse-Patient Relations
    Language English
    Size x, 358 p.
    Edition 4th ed.
    Publisher Saunders
    Publishing place Philadelphia
    Document type Book
    ISBN 9780721621623 ; 0721621627
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Book: Psychodynamic nursing;

    Brown, Martha Montgomery / Fowler, Grace R

    a biosocial orientation [by] Martha Montgomery Brown [and] Grace R. Fowler

    1966  

    MeSH term(s) Nurse-Patient Relations ; Psychiatric Nursing
    Language English
    Size xvi, 323 p.
    Edition 3d ed.
    Publisher Saunders
    Publishing place Philadelphia
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  7. Book: Psychodynamic nursing;

    Brown, Martha Montgomery / Fowler, Grace R

    a biosocial orientation [by] Martha Montgomery Brown [and] Grace R. Fowler

    1961  

    MeSH term(s) Nurse-Patient Relations ; Psychiatric Nursing
    Language English
    Size xiv, 315 p.
    Edition 2d ed.
    Publisher Saunders
    Publishing place Philadelphia
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Book: Psychodynamic nursing,

    Brown, Martha Montgomery / Fowler, Grace R

    1954  

    Author's details by Martha Montgomery Brown and Grace R. Fowler
    Keywords Nursing / Psychiatric
    Language English
    Size xiv, 257 p., ill.
    Publisher Saunders
    Publishing place Philadelphia
    Document type Book
    Database Catalogue of the US National Library of Medicine (NLM)

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